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      • SCOPUSKCI등재

        Use of the Anterolateral Thigh and Vertical Rectus Abdominis Musculocutaneous Flaps as Utility Flaps in Reconstructing Large Groin Defects

        Aslim, Edwin Jonathan,Rasheed, Mohamed Zulfikar,Lin, Fangbo,Ong, Yee-Siang,Tan, Bien-Keem Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.5

        Background Groin dissections result in large wounds with exposed femoral vessels requiring soft tissue coverage, and the reconstructive options are diverse. In this study we reviewed our experience with the use of the pedicled anterolateral thigh and vertical rectus abdominis musculocutaneous flaps in the reconstruction of large groin wounds. Methods Groin reconstructions performed over a period of 10 years were evaluated, with a mean follow up of two years. We included all cases with large or complex (involving perineum) defects, which were reconstructed with the pedicled anterolateral thigh musculocutaneous or the vertical rectus abdominis musculocutaneous (VRAM) flaps. Smaller wounds which were covered with skin grafts, locally based flaps and pedicled muscle flaps were excluded. Results Twenty-three reconstructions were performed for large or complex groin defects, utilising the anterolateral thigh (n=10) and the vertical rectus abdominis (n=13) pedicled musculocutaneous flaps. Femoral vein reconstruction with a prosthetic graft was required in one patient, and a combination flap (VRAM and gracilis muscle flap) was performed in another. Satisfactory coverage was achieved in all cases without major complications. No free flaps were used in our series. Conclusions The anterolateral thigh and vertical rectus abdominis pedicled musculocutaneous flaps yielded consistent results with little morbidity in the reconstruction of large and complex groin defects. A combination of flaps can be used in cases requiring extensive cover.

      • KCI등재

        Phenolic Composition and Antimicrobial and Antioxidant Activities of Leucoagaricus leucothites (Vittad.) Wasser

        Belma Aslim,Sahlan Ozturk 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.11

        Leucoagaricus leucothites (Vittad.) Wasser is an edible macrofungus found limitedly in Turkey. The ethanolic extract of L. leucothites has shown strong antimicrobial activity against some foodborne and spoilage bacteria. Therefore, the phenolic composition of L. leucothites ethanolic extract was analyzed by using high-performance liquid chromatography. Catechin (288 mg/L) was found to be the major component in the extract. Antioxidant activity of the extract was evaluated by studying the scavenging ability of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, and chelating ability of the extract was assessed in a ferrous ion assay. The scavenging effect on DPPH radicals was 71% at 10 mg/mL, whereas the chelating effect on ferrous ions was 82% at 15 mg/mL. The total contents of phenol (3.40±0.5 mg/g), ascorbic acid (2.10±0.3 mg/g), β-carotene (0.02±0.0 mg/g), and lycopene (0.01±0.0 mg/g) in the macrofungi ethanolic extract were also determined.

      • KCI등재

        Use of the Anterolateral Thigh and Vertical Rectus Abdominis Musculocutaneous Flaps as Utility Flaps in Reconstructing Large Groin Defects

        Edwin Jonathan Aslim,Mohamed Zulfikar Rasheed,Fangbo Lin,Yee-Siang Ong,Bien-Keem Tan 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.5

        Background: Groin dissections result in large wounds with exposed femoral vessels requiringsoft tissue coverage, and the reconstructive options are diverse. In this study we reviewed ourexperience with the use of the pedicled anterolateral thigh and vertical rectus abdominismusculocutaneous flaps in the reconstruction of large groin wounds. Methods: Groin reconstructions performed over a period of 10 years were evaluated, with amean follow up of two years. We included all cases with large or complex (involving perineum)defects, which were reconstructed with the pedicled anterolateral thigh musculocutaneous orthe vertical rectus abdominis musculocutaneous (VRAM) flaps. Smaller wounds which werecovered with skin grafts, locally based flaps and pedicled muscle flaps were excluded. Results: Twenty-three reconstructions were performed for large or complex groin defects,utilising the anterolateral thigh (n=10) and the vertical rectus abdominis (n=13) pedicledmusculocutaneous flaps. Femoral vein reconstruction with a prosthetic graft was required inone patient, and a combination flap (VRAM and gracilis muscle flap) was performed inanother. Satisfactory coverage was achieved in all cases without major complications. No freeflaps were used in our series. Conclusions: The anterolateral thigh and vertical rectus abdominis pedicled musculocutaneousflaps yielded consistent results with little morbidity in the reconstruction of large and complexgroin defects. A combination of flaps can be used in cases requiring extensive cover.

      • SCIESCOPUSKCI등재

        ON STRONGLY θ-e-CONTINUOUS FUNCTIONS

        Ozkoc, Murad,Aslim, Gulhan Korean Mathematical Society 2010 대한수학회보 Vol.47 No.5

        A new class of generalized open sets in a topological space, called e-open sets, is introduced and some properties are obtained by Ekici [6]. This class is contained in the class of $\delta$-semi-preopen (or $\delta-\beta$-open) sets and weaker than both $\delta$-semiopen sets and $\delta$-preopen sets. In order to investigate some different properties we introduce two strong form of e-open sets called e-regular sets and e-$\theta$-open sets. By means of e-$\theta$-open sets we also introduce a new class of functions called strongly $\theta$-e-continuous functions which is a generalization of $\theta$-precontinuous functions. Some characterizations concerning strongly $\theta$-e-continuous functions are obtained.

      • KCI등재

        In Vitro Antimicrobial Effect of Satureja wiedemanniana Against Bacillus Species Isolated from Raw Meat Samples

        Yuce, Nihal,Aslim, Belma,Ozdogan, Hakan The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.4

        In this study a total of 30 raw meat samples obtained from Ankara, Turkey were screened for the presence of Bacillus species. Among the meat samples analyzed, the predominant species isolated was Bacillus circulans; other Bacillus species were identified as Bacillus firmus, Bacillus lentus, Bacillus megaterium, Bacillus licheniformis, Bacillus mycoides, Bacillus sphaericus, and Bacillus cereus. Minced meat samples were more contaminated with Bacillus species than sliced beef sample. From these samples, 242 Bacillus species isolates were obtained, which were investigated for proteolytic and lipolytic activity, associated with meat spoilage. Interestingly, some Bacillus strains produced the highest values of proteolytic/lipolytic activities. Nineteen Bacillus strains were selected among the 242 isolates according to their proteolytic/lipolytic activity with a clear zone diameter of ${\geq}6\;mm$. The essential oil of Satureja wiedemanniana (Lalem) Velen was also tested against these 19 Bacillus species that had proteolytic and lipolytic activity. The essential oil yield obtained from the aerial parts of the plant was 0.35% (vol/wt). The inhibition zones of the essential oil obtained against all the Bacillus species were in the range of 5.0.12.0 mm. The oil showed high antimicrobial activities against B. licheniformis M 6(26), M 11(16), and M 12(1) strains. B. licheniformis 12(1) showed high lipolytic activity (18.0 mm). Also, B. licheniformis M 6(26) and M 11(16) showed high proteolytic activity (16.0 and 14.0 mm). These results may suggest that an essential oil of S. wiedemanniana can be used as a natural preservative in meat against spoilage bacteria.

      • KCI등재

        In Vitro Antimicrobial Effect of Satureja wiedemanniana Against Bacillus Species Isolated from Raw Meat Samples

        Nihal Yucel,Belma Aslim,Hakan Özdoğan 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.4

        the presence of Bacillus species. Among the meat samples analyzed, the predominant species isolated was Bacillus circulans; other Bacillus species were identified as Bacillus firmus, Bacillus lentus, Bacillus megaterium, Bacillus licheniformis, Bacillus mycoides, Bacillus sphaericus, and Bacillus cereus. Minced meat samples were more contaminated with Bacillus species than sliced beef sample. From these samples, 242 Bacillus species isolates were obtained, which were investigated for proteolytic and lipolytic activity, associated with meat spoilage. Interestingly, some Bacillus strains produced the highest values of proteolytic/lipolytic activities. Nineteen Bacillus strains were selected among the 242 isolates according to their proteolytic/lipolytic activity with a clear zone diameter of ≥6mm. The essential oil of Satureja wiedemanniana (Lalem) Velen was also tested against these 19 Bacillus species that had proteolytic and lipolytic activity. The essential oil yield obtained from the aerial parts of the plant was 0.35% (vol/wt). The inhibition zones of the essential oil obtained against all the Bacillus species were in the range of 5.0–12.0mm. The oil showed high antimicrobial activities against B. licheniformis M 6(26), M 11(16), and M 12(1) strains. B. licheniformis 12(1) showed high lipolytic activity (18.0mm). Also, B. licheniformis M 6(26) and M 11(16) showed high proteolytic activity (16.0 and 14.0mm). These results may suggest that an essential oil of S. wiedemanniana can be used as a natural preservative in meat against spoilage bacteria.

      • KCI등재

        ON STRONGLY θ-e-CONTINUOUS FUNCTIONS

        Murad Özkoc,Gülhan Aslim 대한수학회 2010 대한수학회보 Vol.47 No.5

        A new class of generalized open sets in a topological space,called e-open sets, is introduced and some properties are obtained by Ekici [6]. This class is contained in the class of δ-semi-preopen (or δ-β-open) sets and weaker than both δ-semiopen sets and δ-preopen sets. In order to investigate some different properties we introduce two strong form of e-open sets called e-regular sets and e-θ-open sets. By means of e-θ-open sets we also introduce a new class of functions called strongly θ-e-continuous functions which is a generalization of θ-precontinuous functions. Some characterizations concerning strongly θ-e-continuous functions are obtained.

      • KCI등재

        Comparison of Antioxidant Capacities of Ganoderma lucidum (Curtis) P. Karst and Funalia trogii (Berk.) Bondartsev & Singer by Using Different In Vitro Methods

        Hande Yegenoglu,Belma Aslim,Feyza Oke 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.5

        The aim of the study was to investigate antioxidant activities of Ganoderma lucidum and Funalia trogii. Ethanol and water crude extracts from G. lucidum and F. trogii were investigated for their antioxidant capacity in some different assays, namely, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, metal chelating activity against ferrous ions, and plasma lipid peroxidation inhibitory. In addition, the amounts of total phenol, ascorbic acid, β-carotene, and lycopene components in the extracts were determined. Among the four mushroom extracts, G. lucidum water extract and G. lucidum ethanol extract showed the highest scavenging activity against DPPH radicals (50% inhibitory concentration = 0.055 ± 0.001 mg/mL). Total phenol was the major antioxidant component found in the mushroom extracts. These results showed that G. lucidum may be used in pharmaceutical applications because of its effective antioxidant properties.

      • SCIESCOPUSKCI등재

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