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- 저자 : Arnon Lambroza (검색결과 2 건)
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The Learning Curve for Peroral Endoscopic Myotomy in Latin America: A Slide to the Right?
Michel Kahaleh,Amy Tyberg,Supriya Suresh,Arnon Lambroza,Fernando Rodriguez Casas,Mario Rey,Jose Nieto,Guadalupe Ma Martínez,Felipe Zamarripa,Vitor Arantes,Maria G Porfilio,Monica Gaidhane,Pietro Fami 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.5
Background/Aims: Peroral endoscopic myotomy (POEM) has been increasingly used for achalasia in Latin America, where Chagasdisease is prevalent, and this makes POEM more challenging. The aim of this study was to determine the learning curve for POEMin Latin America. Methods: Patients undergoing POEM in Latin America with a single operator were included from a prospective registry over 4 years. Non-linear regression and cumulative sum control chart (CUSUM) analyses were conducted for the learning curve. Results: A total of 125 patients were included (52% male; mean age, 59 years), of which 80 had type II achalasia (64%), and 38 hadChagas disease (30%). The average pre-procedure and post-procedure Eckardt scores were 6.79 and 1.87, respectively. Technicalsuccess was achieved in 93.5% of patients, and clinical success was achieved in 88.8%. Adverse events occurred in 27 patients (22%)and included bleeding (4 patients), pneumothorax (4 patients), mucosal perforation (13 patients), mediastinitis (2 patients), andleakage (4 patients). The CUSUM chart showed a median procedure time of 97 min (range, 45-196 min), which was achieved at the 61st procedure. Procedure duration progressively decreased, with the last 10 procedures under 50 min approaching a plateau (p-value <0.01). Conclusions: Mastering POEM in Latin America requires approximately 61 procedures for both POEM efficiency and to accomplishthe procedure within 97 minutes.
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Peroral Endoscopic Myotomy: Establishing a New Program
Nikhil A. Kumta,Shivani Mehta,Prashant Kedia,Kristen Weaver,Reem Z. Sharaiha,Norio Fukami,Hitomi Minami,Fernando Casas,Monica Gaidhane,Arnon Lambroza,Michel Kahaleh 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.5
Achalasia is an esophageal motility disorder characterized by incomplete relaxation of the lower esophageal sphincter (LES) and aperistalsis of the esophageal body. Treatment of achalasia is aimed at decreasing the resting pressure in the LES. Peroral endoscopic myotomy (POEM), derived from natural orifice transluminal endoscopic surgery (NOTES) and advances in endoscopic submucosal dissection (ESD), presents a novel, minimally invasive, and curative endoscopic treatment for achalasia. POEM involves an esophageal mucosal incision followed by creation of a submucosal tunnel crossing the esophagogastric junction and myotomy before closure of the mucosal incision. Although the procedure is technically demanding and requires a certain degree of skill and competency, treatment success is high (90%) with low complication rates. Since the first described POEM in humans in 2010, it has been used increasingly at centers worldwide. This article reviews available published clinical studies demonstrating POEM efficacy and safety in order to present a proposal on how to establish a dedicated POEM program and reach base proficiency for the procedure.
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