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        Combinatorial and geometric optimization of a parabolic trough solar collector

        Anubhav Goel,Gaurav Manik,Om Prakash Verma 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.2

        The current investigation reveals the need for combinatorial and geometric optimization for parabolic trough solar collectors (PTSCs) and proposes methods to perform them. An analytical model of PTSC was drafted, which emerged to be quite accurate when exhaustively validated using experimental results. The analysis reveals that superior properties of design components (solar selective absorber coatings (SSACs), heat transfer fluids (HTFs), etc.) cannot guarantee better performance, as there are many interacting factors. Also, a particular combination of components can perform better at a certain temperature while lagging at another. To acquire an optimal combination of components, combinatorial optimization is introduced and carried out for PTSCs, using genetic algorithm (GA). Six SSACs, three absorber materials, and five HTFs are considered, significant efficiency improvements of 8% at 150 oC and 6% at 300 oC are observed. This study discloses that geometrical parameters (length and width of collector, focal length, etc.) possess positive as well negative impacts on efficiency. By varying these in a reasonable range, optimal values that lead to improved efficiency can be obtained. Particle swarm optimization (PSO) is used to attain this geometric optimization, and improvement of 3% in efficiency is noticed by only ±5% variation in dimensions.

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        Evaluation of commercial probiotic lactic cultures against biofilm formation by Cronobacter sakazakii

        ( Anubhav Jamwal ),( Kavita Sharma ),( Rajni Chauhan ),( Saurabh Bansal ),( Gunjan Goel ) 대한장연구학회 2019 Intestinal Research Vol.17 No.2

        Background/Aims: Cronobacter sakazakii, an emergent pathogen is considered as a major concern to infants and neonates fed on reconstituted powdered infant milk formula. In conjunction with many other factors, biofilm forming capacity adds to its pathogenic potential. In view of the facts that infants are at highest risk to C. sakazakii infections, and emerging antibiotic re-sistance among pathogens, it is imperative to evaluate probiotic cultures for their efficacy against C. sakazakii. Therefore, pure probiotic strains were isolated from commercial probiotic products and tested for their antimicro-bial and anti-biofilm activities against C. sakazakii. Methods: A total of 6 probiotic strains were tested for their antibiotic susceptibility followed by antimicrobial activity using cell-free supernatant (CFS) against C. sakazakii. The inhibitory activity of CFS against biofilm formation by C. sakazakii was determined using standard crystal violet assay and microscopic observations. Results: All the probiotic strains were sensitive to ampicillin, tetracycline, vancomycin and carbenicillin whereas most of the strains were resistant to erythro-mycin and novobiocin. Four of the 6 probiotic derived CFS possessed antimicrobial activity against C. sakazakii at a level of 40 μL. A higher biofilm inhibitory activity (>80%) was observed at initial stages of biofilm formation with weaker activity during longer incubation upto 48 hours (50%.60%). Conclusions: The study indicated the efficacy of isolated commercial probiotics strains as potential inhibitor of biofilm formation by C. sakazakii and could be further explored for novel bioactive molecules to limit the emerging infections of C. sakazakii. (Intest Res 2019;17:192-201.)

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