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- 저자 : Antonio Nieto (검색결과 2 건)
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Software for Simulating Open-pit Truck/Shovel Haulage Systems using Google Earth and GPSS/H
최요순,Antonio Nieto 한국자원공학회 2011 한국자원공학회지 Vol.48 No.6
This study presents new software, named Google Earth-based MIning SIMulation System(GEMISIMS), to simulate a truck/shovel haulage system in open-pit mines. System architecture using Google Earth, Keyhole Markup Language (KML), a modified least-cost path algorithm and the GPSS/H simulation language was suggested and used for the implementation of GEMISIMS. GEMISIMS allows users: (1) to determine optimal haulage routes of trucks between shovels and dumps(or ore stockpiles), (2) to optimize the number of trucks which will be allocated to each route and (3) to animate the movements of trucks using the 3D render window of Google Earth. This paper reports the concept and details of the software development and its application to an open-pit coal mine in Indonesia which revealed that GEMISIMS can support the better understanding of an open-pit truck/shovel haulage system.
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Ángel Aragón,María Cebro-Márquez,Eliseo Perez,Antonio Pazos,Ricardo Lage,José Ramón González-Juanatey,Isabel Moscoso,Carmen Bao-Varela,Daniel Nieto 한국생체재료학회 2020 생체재료학회지 Vol.24 No.3
Background: Cardio myoblast generation from conventional approaches is laborious and time-consuming. We present a bioelectronics on-a-chip for stimulating cells cardio myoblast proliferation during culture. Method: The bioelectronics chip fabrication methodology involves two different process. In the first step, an aluminum layer of 200 nm is deposited over a soda-lime glass substrate using physical vapor deposition and selectively removed using a Q-switched Nd:YVO4 laser to create the electric tracks. To perform the experiments, we developed a biochip composed of a cell culture chamber fabricated with polydimethylsiloxane (PDMS) with a glass coverslip or a cell culture dish placed over the electric circuit tracks. By using such a glass cover slip or cell culture dish we avoid any toxic reactions caused by electrodes in the culture or may be degraded by electrochemical reactions with the cell medium, which is crucial to determine the effective cell-device coupling. Results: The chip was used to study the effect of electric field stimulation of Rat ventricular cardiomyoblasts cells (H9c2). Results shows a remarkable increase in the number of H9c2 cells for the stimulated samples, where after 72 h the cell density double the cell density of control samples. Conclusions: Cell proliferation of Rat ventricular cardiomyoblasts cells (H9c2) using the bioelectronics-on-a-chip was enhanced upon the electrical stimulation. The dependence on the geometrical characteristics of the electric circuit on the peak value and homogeneity of the electric field generated are analyzed and proper parameters to ensure a homogeneous electric field at the cell culture chamber are obtained. It can also be observed a high dependence of the electric field on the geometry of the electrostimulator circuit tracks and envisage the potential applications on electrophysiology studies, monitoring and modulate cellular behavior through the application of electric fields.
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