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Zahra Alizadeh Tabari,Abbas Azadmehr,Mohammad Amir Alizadeh Tabrizi,Jalaloddin Hamissi,Fatemeh Baharak Ghaedi 대한치주과학회 2013 Journal of Periodontal & Implant Science Vol.43 No.5
Purpose: The receptor activator of nuclear factor kappa B (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system plays a significant role in osteoclastogenesis, activation of osteoclasts, and regulation of bone resorption. This study aimed to evaluate the use of the salivary soluble RANKL (sRANKL)/OPG ratio as a diagnostic marker for periodontitis in nonsmokers. Methods: Twenty-five patients with chronic periodontitis and 25 individuals with a healthy periodontium were enrolled in this study. Samples containing 5 mL of unstimulated saliva were obtained from each subject. Salivary sRANKL and OPG concentrations were determined using a standard enzyme-linked immunosorbent assay. Statistical analysis was performed using SPSS ver. 18.0. Results: The levels of sRANKL and OPG were detectable in all of the samples. Positive relationships were found between the plaque index and clinical attachment level and both the salivary concentration of sRANKL and the salivary sRANKL/OPG ratio (P<0.05). The salivary concentration of sRANKL and the sRANKL/OPG ratio were significantly higher in the periodontitis group than in the healthy group (P=0.004 and P=0.001, respectively). In contrast, the OPG concentration showed no significant differences between the groups (P=0.455). Conclusions: These findings suggest that the salivary sRANKL/OPG ratio may be helpful in the screening and diagnosis of periodontitis. However, longitudinal studies with larger populations are needed to confirm these results. Purpose: The receptor activator of nuclear factor kappa B (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system plays a significant role in osteoclastogenesis, activation of osteoclasts, and regulation of bone resorption. This study aimed to evaluate the use of the salivary soluble RANKL (sRANKL)/OPG ratio as a diagnostic marker for periodontitis in nonsmokers. Methods: Twenty-five patients with chronic periodontitis and 25 individuals with a healthy periodontium were enrolled in this study. Samples containing 5 mL of unstimulated saliva were obtained from each subject. Salivary sRANKL and OPG concentrations were determined using a standard enzyme-linked immunosorbent assay. Statistical analysis was performed using SPSS ver. 18.0. Results: The levels of sRANKL and OPG were detectable in all of the samples. Positive relationships were found between the plaque index and clinical attachment level and both the salivary concentration of sRANKL and the salivary sRANKL/OPG ratio (P<0.05). The salivary concentration of sRANKL and the sRANKL/OPG ratio were significantly higher in the periodontitis group than in the healthy group (P=0.004 and P=0.001, respectively). In contrast, the OPG concentration showed no significant differences between the groups (P=0.455). Conclusions: These findings suggest that the salivary sRANKL/OPG ratio may be helpful in the screening and diagnosis of periodontitis. However, longitudinal studies with larger populations are needed to confirm these results.
Tabari, Zahra Alizadeh,Azadmehr, Abbas,Tabrizi, Mohammad Amir Alizadeh,Hamissi, Jalaloddin,Ghaedi, Fatemeh Baharak Korean Academy of Periodontology 2013 Journal of Periodontal & Implant Science Vol.43 No.5
Purpose: The receptor activator of nuclear factor kappa B (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system plays a significant role in osteoclastogenesis, activation of osteoclasts, and regulation of bone resorption. This study aimed to evaluate the use of the salivary soluble RANKL (sRANKL)/OPG ratio as a diagnostic marker for periodontitis in nonsmokers. Methods: Twenty-five patients with chronic periodontitis and 25 individuals with a healthy periodontium were enrolled in this study. Samples containing 5 mL of unstimulated saliva were obtained from each subject. Salivary sRANKL and OPG concentrations were determined using a standard enzyme-linked immunosorbent assay. Statistical analysis was performed using SPSS ver. 18.0. Results: The levels of sRANKL and OPG were detectable in all of the samples. Positive relationships were found between the plaque index and clinical attachment level and both the salivary concentration of sRANKL and the salivary sRANKL/OPG ratio (P<0.05). The salivary concentration of sRANKL and the sRANKL/OPG ratio were significantly higher in the periodontitis group than in the healthy group (P=0.004 and P=0.001, respectively). In contrast, the OPG concentration showed no significant differences between the groups (P=0.455). Conclusions: These findings suggest that the salivary sRANKL/OPG ratio may be helpful in the screening and diagnosis of periodontitis. However, longitudinal studies with larger populations are needed to confirm these results.
Shape and Orifice Optimization of Airbag Systems for UAV Parachute Landing
Alizadeh, Masoud,Sedaghat, Ahmad,Kargar, Ebrahim The Korean Society for Aeronautical and Space Scie 2014 International Journal of Aeronautical and Space Sc Vol.15 No.3
An airbag is an important safety system and is well known as a safety system in cars during an accident. Airbag systems are also used as a shock absorber for UAVs to assist with rapid parachute landings. In this paper, the dynamics and gas dynamics of five airbag shapes, cylindrical, semi-cylindrical, cubic, and two truncated pyramids, were modelled and simulated under conditions of impact acceleration lower than $4m/s^2$ to avoid damage to the UAV. First, the responses of the present modelling were compared and validated against airbag test results under the same conditions. Second, for each airbag shape under the same conditions, the responses in terms of pressure, acceleration, and emerging velocity were investigated. Third, the performance of a pressure relief valve is compared with a fixed-area orifice implemented in the air bag. For each airbag shape under the same conditions, the optimum area of the fixed orifice was determined. By examining the response of pressure and acceleration of the airbag, the optimum shape of the airbag and the venting system is suggested.
Effect of First Line Gastric Cancer Chemotherapy Regime on the AGS Cell Line - MTT Assay Results
Alizadeh-Navaei, Reza,Rafiei, Alireza,Abedian-Kenari, Saeid,Asgarian-Omran, Hossein,Valadan, Reza,Hedayatizadeh-Omran, Akbar Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.1
Background: Combination chemotherapy regimes are common treatments for cancer. The aim of this study was to evaluation the effect of individual chemotherapeutic agents in comparison with a first line chemotherapy regime treatment in the AGS gastric cancer cell line by MTT assay. Materials and Methods: In this experimental study, AGS cells were grown in RPMI-1640 supplemented with 10% fetal calf serum and 100 IU/ml penicillin, and $10{\mu}g/ml$ streptomycinin, under a humidified condition at $37^{\circ}C$ with 5% CO2. All cells were washed with PBS and detached with trypsin, centrifuged and 8000 cells re-plated on to 96- well plates. LD50 doses of Epirubicin, Cisplatin and 5-fluorouracil were added to each well in mono or triple therapy. Anti-proliferative activities were determined by MTT assay after 24, 48 or 72 h. Results: Results of MTT assays showed that there were no significant differences among 3 drugs in monotherapy (p=0.088), but there was significant difference between combination therapy with epirubicin (P=0.031) and 5FU (p=0.013) on cell survival at 24 h. After 48 and 72 hours, cell viability showed significant differences between the 3 drugs (p=0.048 and P=0.000 for 48 and 72 h, respectively) and there was significant difference between combination therapy with epirubicin (P=0.035 and P=0.002 for 48 and 72 h, respectively). Conclusions: The results showed no significant differences between these chemotherapy drugs each given alone, but combination therapy with 3 drugs had significant effects on cell viability in comparison with epirubicin alone.
ON FRAMES FOR COUNTABLY GENERATED HILBERT MODULES OVER LOCALLY C<sup>*</sup>-ALGEBRAS
Alizadeh, Leila,Hassani, Mahmoud Korean Mathematical Society 2018 대한수학회논문집 Vol.33 No.2
Let $\mathcal{X}$ be a countably generated Hilbert module over a locally $C^*$-algebra $\mathcal{A}$ in multiplier module M($\mathcal{X}$) of $\mathcal{X}$. We propose the necessary and sufficient condition such that a sequence $\{h_n:n{{\in}}\mathbb{N}\}$ in M($\mathcal{X}$) is a standard frame of multipliers in $\mathcal{X}$. We also show that if T in $b(L_{\mathcal{A}}(\mathcal{X}))$, the space of bounded maps in set of all adjointable maps on $\mathcal{X}$, is surjective and $\{h_n:n{{\in}}\mathbb{N}\}$ is a standard frame of multipliers in $\mathcal{X}$, then $\{T{\circ}h_n:n{\in}\mathbb{N}}$ is a standard frame of multipliers in $\mathcal{X}$, too.
Alizadeh, Alireza,Javan-Nikkhah, Mohammad,Fotouhifar, Khalil-Berdi,Motlagh, Elahe Rabiee,Rahjoo, Vahid The Korean Society of Plant Pathology 2010 Plant Pathology Journal Vol.26 No.3
Fusarium proliferatum is the causal agent of stalk and root rot disease of maize, foot rot disease of rice, basal and root rot disease of onion and knife cut disease of sugarcane in Iran. In recent years, incidence and severity of these diseases have been increased in Iran. Fifty seven F. proliferatum single-spore isolates collected from diseased maize, rice, onion and sugarcane plants at different areas were used to study genetic diversity by determination of vegetative compatibility groups (VCGs). Chlorate-resistant nitrate non-utilizing (nit) mutants were recovered from selected isolates of F. proliferatum and used in complementation tests. All isolates in which both nit1 and NitM (or nit3) mutants were recovered, demonstrated self-compatibility. Vegetative compatibility tests by pairing nit mutants identified 30 VCGs among 57 isolates. Twenty-three isolates belonged to singlemember VCGs and the remaining 34 isolates, belonged to other seven multimember VCGs. Segregation of F. proliferatum isolates obtained from various area and host plants into different VCGs in Iran is reported for the first time. In this study, none of isolates obtained from rice complemented with any other isolates from onion and sugarcane and, non complementation occurred between onion and sugarcane isolates. Also, only one complementation occurred between one isolate of maize and one isolate of sugarcane and rice. Thus, a correlation between VCGs grouping and host preferences was founded. It is concluded that natural populations of F. proliferatum in Iran are probably genetically divergent and include isolates representing a potential risk for disease development.
A new hydrogen cyanide chemiresistor gas sensor based on graphene quantum dots
Alizadeh, Taher,Shokri, Mahrokh,Hanifehpour, Younes,Joo, Sang Woo Taylor Francis 2016 International journal of environmental analytical Vol.96 No.8
<P>Graphene quantum dot (GQDs), synthesised via controlled carbonisation of citric acid, were reduced by hydrazine hydrate and then used as hydrogen cyanide (HCN) gas sensors. Checking of the reduction step by Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) techniques revealed that most of the oxygen-containing functional groups were removed from the GQDs. It was observed the reduction process is necessary for sensitising of GQDs for HCN gas. The electrical resistance of the reduced GQDs was increased as a result of their exposure to HCN gas. Accepting a p-type semiconducting characteristic for GQD material, he above-mentioned behaviour suggested electron donation from HCN to GQD. The sensor response to HCIsil gas was reversible, suggesting a reversible adsorption/desorption phenomenon of HCN to the GQDs. The response as well as the recovery time of the sensor was different depending on the HCN concentration tested. The developed sensor showed linear HCN response from 1 to 100 ppm. The detection limit of the sensor was estimated to be 0.6 ppm (SIN). Relative standard deviation f HCN determination by the developed sensor was calculated to be 5.7% (n = 4, [HCN]= 50 ppm). The sensor response was did not vary significantly within 6 months</P>
A Ca<sup>2+</sup> selective membrane electrode based on calcium-imprinted polymeric nanoparticles
Alizadeh, Taher,Shamkhali, Amir Naser,Hanifehpour, Younes,Joo, Sang Woo CNRS 2016 NEW JOURNAL OF CHEMISTRY Vol.40 No.10
<P>In this work, a Ca2+ selective PVC-membrane electrode, utilizing nano-sized Ca2+ imprinted polymers as the ionophore, was introduced. The imprinted polymer was prepared by precipitation polymerization in acetonitrile. Various types of commercially available functional monomers including methacrylic acid, acrylic acid and itaconic acid were tested for the synthesis of Ca2+-imprinted polymers. The networked polymers obtained were used as the ionophore of PVC membrane electrodes. The potentiometric responses of the electrodes, prepared using different imprinted polymers, showed that the type of functional monomers used had a crucial effect on the analytical characteristics of the related membrane electrode. The membrane electrode composed of itaconic acid based imprinted polymers showed better Nernstian slope and particularly better selectivity for Ca2+ determination. The effectiveness of itaconic acid for complex formation with Ca2+, in comparison to two other monomers (methacrylic acid and acrylic acid), was demonstrated by density functional theory-based calculations. The type of crosslinker agent had a definitive role in the performance of the related electrode. Divinyl benzene based imprinted polymers led to an electrode with no significant sensitivity for Ca2+; whereas, the utilization of ethylene glycol dimethacrylate led to a sensor with ideally Nernstian response. Other components of the membrane such as the plasticizer and ionic additive as well as the solution pH were evaluated and appropriate conditions were selected. The electrode showed a response time of 10 s with no memory effect. A dynamic linear range of 1 x 10(-6)-1 x 10(-1) mol L-1, a Nernstian slope of 30.3 (+/-0.4) mV decade(-1) and a detection limit of 7.5 x 10(-7) mol L-1 were obtained for the electrode. The utility of the electrode was checked by its use as an indicator electrode in the determination of Ca2+ ions via complexometric titration by EDTA.</P>