젖소의 유방염대책

한홍율,Han Hong Ryul 대한수의사회 1980 대한수의사회지 Vol.16 No.1

Today 100 thousand dairy cows will be milked in Korea. A reasonable estimate of the prevelence of mastitis today in Korea is approximately $60\%$ of the cows infected-in an average of two quarters per cow. The greater part of the mastitis infec

개의 바이러스성(性) 장염(腸炎)의 국내발생례(國內發生例) 보고(報告)

한홍율,황의경,유규연,이영옥,Han, Hong-Ryul,Hwang, Eui-Kyung,Yoo, Gyu-Yeon,Rhee, Young-Ok 대한수의학회 1982 大韓獸醫學會誌 Vol.22 No.2

An acute enteric diseases accompanied with vomiting, diarrhea, anorexia, pyrexia, dehydration and high mortality has occured in dogs throughout the country since June, 1981 in Korea. According to epidemiological and clinico-pathological studies on the total of 44 dogs admitted to the animal clinic in the college, the cases were tentatively diagnosed as a viral enteritis and the possibility of canine parvovirus as the etiological agent for the cases was discussed.

젖소에서 우군건강관리의 지표

한홍율,정순옥,Han Hong-Ryul,Jeong Soon-Wuk 대한수의사회 1994 대한수의사회지 Vol.30 No.4

For the establishment of goals of herd management in cows index of feeding's program, nutrional status, fertility, mastitis and foot lameness is mentioned, respectively. Status of he feeding's program is controlled by consistence of feces, cud chewing, ab

유우유방의 유방염에 대한 자연방어기전

한홍율,Han Hong-Ryul 한국임상수의학회 1986 한국임상수의학회지 Vol.3 No.1

This paper reviews the mechanisms effecting host defense in the mammary gland and assesses their possible in preventing of bovine mastitis. The streak canal is the first line of defense against invading mastitis pathogens, providing a physical barrier and antibacterial substances. The milk leukocytes are a second defense line by ingesting pathogens breached the streak canal by multiplication, physical passage, and propulsion during milking. Leukocytosis in milk and enhancement of the phagocytic defense machanisms of the udder were accomplished by inserting intramammary devices. Milk antibodies serum derived and synthesized in mamma tissue aggregate and opsonise bacteria, agglutinate and neutralise toxins, and inhibit. binding of bacteria to epitherial surfaces. Vaccination generally has been unsuccessful because protection is not absolute, but immunization is useful in controlling specific pathogens. Immunostimulant to enhance locally the protective nature of antibody-producing plasma cells concentrated in internal teat end tissue may be effective in reducing the occurrence of infection, but ineffective in preventing intramammary infections.

서울지역에서 문제되고 있는 강아지의 급성설사증에 관한 병인학적 연구

한홍율,박희명,이진희,오태호,정순욱,윤신근,박철만,Han Hong-Ryul,Park Hee-Myung,Lee Jin-Hee,Oh Tae-Ho,Jeong Soon-Wuk,Youn Sin-Keun,Park Cheol-Man 한국임상수의학회 1993 한국임상수의학회지 Vol.10 No.2

In Seoul area, there are so many kennel clubs, veterinary hospital, pet establishment and breeding confers that various problems have occurred. They are crowed pet houses, poor sanitation, stress to puppies, sudden environmental changes to puppies and unvaccination against parvovirus, canine distemper virus, parainfluenza virus, infectious hepatitis caused by Adenovirus type I and Leptospira. Several studies were made to survey the infectious agents involved in acute diarrhea of poppies in Seoul are, such as history taking, physical examination, complete blood count and serum chemistry, histopathological finding, bacterial isolation and identification, and hemagglutination test in feces and hemagglutination inhibition test in serum against parvovirus, respectively. The results obtained are summarized as followed. 1. The percent of PCV (30.5$\pm$5.6) and concentration of Total protein(5.0$\pm$0.8) resulted from statistical analysis are significantly lower than normal values (p<0.05), respectively. In addition, fibrinogen (505$\pm$326) was significantly higher an normal value (p<0.001), Band neutrophil (22.9$\pm$12.7) showed signifiant difference (P<0.01). decreased monocyte (3.2$\pm$2.1) and eosinophil (0.7$\pm$0.8) values appeared statistically significant (p<0.001), lymphocyte (16.7$\pm$9), as well. 2. The concentrations of calcium .(8.0$\pm$2.8), glucose (40.1$\pm$31.4), and albumin (2.0$\pm$0.39) were lower than normal values (p<0.01, p<0.01, p<0.001), respectively. Also Inorganic phosphate (7.1$\pm$2.4), pH (p<7.9f:0.2), and Blood Urea Nitrogen (40.41=37.1) were significantly higher than normal values (p<0.001, p(0.001, p<0.05), respectively. 3. Simple and mixed infections occupied 18% and 82% in the distribution of causes in puppies with acute diarrhea, respectively. 4. As puppies got older, incidence of acute diarrhea caused by Staphylococcus aureus was decreased to 13% and infection of canine distemper virus was increased to 53%, but E coli and canine parvovirus always showed high frequency of outbreak in the body weight ranged from 35g to 7.8Kg. 5. As showed in table 5, infections of E coli and Canine Parvovirus showed high outbreak regardless of the age which is classified into three stages, 35~50 day, 60 day and 75~day to 1 year, canine distemper virus appeared increased, but in case of Staphylococcus aureus, visa versa. 6. In comparison wi methods for the laboratory diagnosis diagnosis parvovirus, Hemagglutination test showed positive reaction in 25% and mean serum antibody titer measured by Hemagglutination inhibition test showed 2779 (n=20). In addition, positive reaction was 90% (18/20). 7. In histopathological studies, enteritic and pneumonic lesions were indicated in 53.7% and 39.5% of samples, respectively. 8. Etiologic diagnosis based on the history taking, clinical signs and histopathological findings in puppies with acute diarrhea and vomiting indicated that 50% of puppies were infected by canine parvovirus and distemper virus. 9. In the parasitological examination made by simple flotation with saturated zinc sulfate tour parasites found were Isospora canis, Toxocara canis, Ancylostoma spp and Toxocara spp. Isospora canis and Toxocara canis were more frequently found among those parasites of diarrhoeic causes in puppies ranged from 35 days to 1 year. Their infestation rates were 15% and 13% respectively.

한우(韓牛)의 관절골액(關節滑液)에 관한 연구(硏究) 1. 경부관절골액(脛부關節滑液)의 성상(性狀)과 세포조성(細胞組成)에 관하여

한홍율,Han, Hong Ryul 대한수의학회 1976 大韓獸醫學會誌 Vol.16 No.2

The gross appearance, cellular constituents, and quality of mucin clot of synovial fluid from the normal tibiotarsal joints of 57 healthy Korean cattle were investigated. The results obtained were summarized as followings. 1. The gross appearance of the synovial fluid were quite clear without any minute particles of flocculent, colourless (78.95%) or slightly yellowish (21.05%), and it did not coagulate within the 24 hours after sampling. 2. The mean number of leucocytes for the entire group was $127.68{\pm}13.84/mm^3$ (SE) with a range of 0 to $627/mm^3$ for individual samples. In the total cell count no significance among the investigated age and sex categories was found. 3. The mean differential values for the groups ware: neutrophil, $9.36{\pm}1.67%$; lymphocyte, $57.66{\pm}8.34%$; monocyte, $24.70{\pm}2.22%$; eosinophil, $1.45{\pm}0.27%$; and macrophage, $5.83{\pm}1.13%$. No basophils were observed in stained smears of synovial fluid. 4. Normal mucin clot quality was recorded for 94.7% of the animals, but 5.3% were observed to have fair mucin clot quality. Quality of mucin clot was approximately equal for bulls, cows, and calves.

국내 사육 유우군의 마이코플라스마균 유방감염에 관한 연구

한홍율,황철용,손대호,김미경,유종현,박선일,오태호,Han, Hong-ryul,Hwang, Cheol-yong,Sohn, Dae-ho,Kim, Mi-kyung,Ryu, Jong-hyun,Pak, Son-il,Oh, Tae-ho 대한수의학회 2000 大韓獸醫學會誌 Vol.40 No.3

This study was performed to investigate Mycoplasma (M) spp. infection status of dairy cow in South Korea. Among 8,485 bulk tank milk collected from dairy farms of the 5 areas, 26 samples (0.30%) were positive for Mycoplasma by direct culture method. The isolation rates of Mycoplasma spp. according to the areas were 0.51% in Kyonggi, 0.16% in Cholla, 0.23% in Gyoungsang, 0.12% in Chungchong, and 0.08% in Kangwon. In the species identification test by indirect immunoperoxidase test, 16 out of 26 isolates were identified as M bovis (61.53%), M bovigenitalium (23.07%), M californicum (7.69%), M alkalescens and Acholeplasma laidlawii (3.84%), respectively. The isolation rate of Mycoplasma spp. from 208 quarter milk samples in culling cows due to severe clinical mastitis was 3.0%. These Mycoplasma spp. were identified as M bovis (62.0%), M bovigenitalium (12.0%), M californicaum (12.0%), and M alkalescens (12.0%). This study shows that the bovine mammary gland infected by Mycoplasma spp. is present in some dairy farms and the routine culture test of bulk tank milk samples for Mycoplasma is needed for a high quality milk promotion services.

뇨중 trypsinogen-2 검출을 이용한 개의 급성 췌장염 진단

한홍율,황철용,박선일,오태호,Han, Hong-ryul,Hwang, Cheol-yong,Pak, Son-il,Oh, Tae-ho 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.5

We performed this study to evaluate the potential clinical marker of urinary trypsinogen-2 together with amylase, lipase and urinary amylase creatinine clearance ratio (ACCR) for the diagnosis of acute pancreatitis in dogs. In the experiment on daily changing patterns of amylase, lipase and ACCR measurements in experimentally induced pancreatitis dogs, compared to values measured in pre-induction state, significant difference was seen in amylase until 5th day of induction, and for lipase significant difference was found during the 7th day of observation period (p < 0.05). No significant difference was found in ACCR for the study period (p > 0.05). On SDS-PAGE analysis of urine from experimentally induced pancreatitis dog, The 26kd band was markedly increased compared with that of normal state and that band was confirmed trypsinogen-2 using substrate interaction and isoelectric focusing assay after being eluted. When assessing the appearance of 26kd band on urine SDS-PAGE 87.1% (range: 50~100%) of experimentally induced pancreatitis dogs showed positive results, whereas no corresponding band was seen in dog without pancreatic disorders. With this result, determination of urinary trypsinogen-2 assay was found to have a high diagnostic value with a 70% of sensitivity and 100% of specificity as a routine test for pancreatitis, although the detection of trypsinogen-2 in urine can be varied on the progression stage of pancreatitis at the initial visit to animal clinic. We therefore suggest that the promising results in this study be used for the development of dipstick test for detecting acute pancreatitis in the future research.

개$\cdot$고양이 귀질병의 임상적 고찰

한홍율,오태호,Han Hong-Ryul,Oh Tae-Ho 대한수의사회 1991 대한수의사회지 Vol.27 No.11

Preventive ear management, early detection and treatment of ear diseases, and effective follow-up evaluations are the best approach to eradicating ear diseases. Up to 50$\%$ of dogs with chronic otitis externa may have concurrent otitis media d

濟州道産 돼지의 有鉤囊虫 感染狀態調査

韓弘栗(Hong Ryul Han) 서울대학교 보건환경연구소 1969 보건학논집 Vol.6 No.1