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젊은 여성에서 물 섭취량에 따른 혈청 High-Sensitivity C-Reactive Protein 농도 변화
김현경(Kim, Hyun-Kyung),김병원(Kim, Byung-Won),이형선(Lee, Hyeong-Seon),조장은(Cho, Jang-Eun),권창오(Kweon, Chang-Oh),류재기(Ryu, Jae-Ki) 한국보건기초의학회 2021 한국보건기초의학회지 Vol.14 No.2
Water is essential for life; however, little is known about the precise amount of water intake that is beneficial for cardiovascular health. This study aimed to determine the impact of water intake amounts on cardiovascular disease (CVD) predictors. We reviewed 40 healthy women and divided them into four groups as follows: control, 1-L, 1.5-L, and 2-L water intake. The participants consumed the indicated amount of water daily. After 2 weeks, we evaluated the participants for changes in physiological conditions and CVD predictors. There was a significant decrease in waist circumference (WC) in all water intake groups except control group. The experiment showed no significant difference in the participants’ blood cell count; however, reduced mean platelet volume was observed in the 2-L intake group. Regarding lipid profiles, high-density lipoprotein cholesterol levels increased significantly in the 2-L intake group. High-sensitivity C-reactive protein levels decreased significantly in the 2-L intake group. Consuming >2 L of water daily may be more effective than consuming <2 L of water daily to reduce the risk of CVD. Therefore, this study suggests that drinking 2 L of water or more daily can help maintain a healthy life and prevent the onset of diseases in adults.
고강도 금속 중공사막을 이용한 음식물 쓰레기 폐수 처리
백귀찬(Gwi-Chan Paik),권창오(Chang-Oh Kweon) 한국환경관리학회 2007 環境管理學會誌 Vol.13 No.4
금속 정밀여과 분리막은 산화금속과 탄소입자를 이용하여 쉽게 제조 될 수 있으며, 제조된 금속막은 중공사 형태로 직경 2㎜, 내경 1㎜, 평균기공 크기는 0.8㎝이며 기공률은 40%인 것으로 측정되었다. 또한, 화학적 안정성과 역세척에서 뛰어난 강도를 보이고 있어 음식물폐수 처리시 역삼투 공정의 전처리 단계로 사용이 적합하며, 금속막의 4종류의 음식물폐수 처리 결과 생물화학적 산소 요구량 (BOD), 화학적 산소 요구량(COD), 총고형물 (SS), 총질소 (T-N), 총인 (T-P)의 제거율은 각각 24~71, 32~72, 86~90, 32~73, 24~82%로 측정되었다. 역삼투 공정까지 처리한 음식물폐수의 최종 처리 수질은 BOD, COD, SS, T-N, T-P의 농도는 각각 76~645, 68~212, 0~21, 110~6.37, 0.02~0.14 ppm으로 측정되었다. A metallic microfiltration (MF) membrane was prepared by using metal oxide and carbon particles. The prepared metallic membrane was hollow fiber type and the outer diameter, inner diameter, mean pore size and porosity of the metallic hollow fiber membrane are 2㎜, 1㎜, 0.8㎜ and 40% respectively. And metallic membranes had good chemical and backwashing resistance so that the they could use a pretreatment of a Reverse Osmosis (RO) system. The results of pretreatment show that average rejections of Biochemical Oxygen Demand (BOD). Chemical Oxygen Demand (COD), Suspended Solids (SS), Total Nitrogen (T-N) and Total phosphorus (T-P) were 24~71, 32-72, 86~90, 32~73 and 24~82% respectively. The last water quality of the RO treatment show that average concentrations of BOD, COD, SS, T-N, T-P were 76~645, 68~212, 0~21, 110~6.37 and 0.02~0.14 ppm respectively.
Plateletpheresis: the Process, Devices, and Indicators of Product Quality
Chul-Soo Jang(장철수),Sung-In Kim(김성인),Hyun-Kyung Kim(김현경),Chang-Oh Kweon(권창오),Byung-Won Kim(김병원),Dong-Chan Kim(김동찬),Yoon Suk Kim(김윤석),Ki-Jong Rhee(이기종),Jae-Ki Ryu(류재기) 한국생명과학회 2014 생명과학회지 Vol.24 No.9
혈소판제제는 출혈질환이나 혈소판의 기능장애 치료를 위해 사용되고 있다. 혈소판성분채집술은 혈액성분채집기를 사용하여 혈소판 성분을 채집하는 방법으로, 성분채집혈소판의 질 평가에는 다양한 지표들이 이용되고 있다. 채집된 혈소판의 생산성은 채집효율(collection efficiency)과 채집률(collection rates)로 평가되고 보관된 혈소판의 질은 in vitro 상에서 시각적 외양, 대사활성도, 양, 혈소판 수, 백혈구 수, 미세입자(microparticles), 그리고 다양한 혈소판 활성 표지자들로 평가된다. 혈소판 활성 표지자들은 여러 연구분야에서도 이용되고 있다. 수혈된 후의 혈소판의 질은 교정증가치(corrected count increment)와 혈소판회복퍼센트(percentage platelet recovery)로 평가된다. 본 논문은 혈소판성분채집술의 채집과정, 사용되는 장비, 성분채집혈소판의 질, 전반적인 효율성, 그리고 질평가 지표들에 대한 리뷰(review)와 함께 다른 혈액성분채집기 간의 기능의 차이점을 비교하였고, 또한 혈소판성분채집술은 구연산염 항응고제에 의한 부작용을 일으킬 수는 있지만 전혈 헌혈시에 실신의 전구증상이나 실신을 일으킬 위험이 있는 헌혈자들에게는 더 안전한 방법임을 보여주고 있다. Platelet products are used to treat hemorrhagic or platelet dysfunction diseases. Plateletpheresis involves collecting the platelet components of blood using an apheresis blood-collection system. Various indicators are available for evaluating the qualities of the apheresis platelets. The productivity of platelet collection is evaluated through both the collection efficiency and collection rates. Platelet storage quality can be evaluated in vitro using several indicators, including visual appearance, metabolic activities, volume, platelet count, white blood cell count, microparticles, and various platelet activation markers. Platelet activation markers have been used as indicators of storage quality in various studies. Post-transfusion platelet quality can be evaluated based on the corrected count increment and the percentage of platelet recovery. Although various studies have investigated the aspects of plateletpheresis, no article has systemically presented assessments of the platelet products obtained from different plateletpheresis devices. The present study provides a review of plateletpheresis, including the specifics of the process, the types of devices employed, the platelet quality, the overall efficacy, and the evaluation indicator qualities. Furthermore, the differences in functionality among the different apheresis devices are discussed. Although adverse reactions to the citrate anti-coagulant have been reported, apheresis processing may provide a safer option for donors who are at a high risk for presyncopal or syncopal reactions related to whole blood collection.