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한대석(D. S. Han),조희제(H. J. Jo) 한국생약학회 1982 생약학회지 Vol.13 No.1
Besides the emodin, three anthraquinone derivatives were isolated from the roots of Polygonum cillinerve (Nakai) Owi. which is indigenous exclusively to Korea. Two of them were identified as physcion and emodin-8-O-β-D-glucoside by m.p., UV, IR and NMR spectra. And the third was converted to physcion and sugar by hydrolysis. The quantitative analysis of free and combined form of emodin and physcion was done by the spectrophotometry.
한냉자극(寒冷刺戟)에 대한 한국해녀의 혈관계 반응(血管系反應)에 관한 연구
백광세,김진경,한대석,강복순,홍석기,Paik, K.S.,Kim, C.K.,Han, D.S.,Kang, B.S.,Hong, S.K. 대한생리학회 1969 대한생리학회지 Vol.3 No.1
Experiments on thermoregulatory responses to cold immersion stimulus were carried out in September, 1968 (summer studies) and February, 1969 (winter studies). Eight each of ama and control subject were selected at random from a same community in Yong-Do Island, Pusan. The results obtained are summarized as follows: 1) The rate of fall in muscle temperature of forearm during a 30 min-immersion in $6^{\circ}C$ water bath was significantly slower in the ama in winter and was about the same in the two groups in summer. However, the magnitude of change in the skin temperature and the heat fluxes observed during immersion period was not significantly different either between groups or between seasons. 2) Both finger blood flow and skin temperature during one hr-immersion in $6^{\circ}C$ water bath decreased significantly in the ama as compared to the control. The magnitude of cold-induced vasodilatation during immersion period was significantly greater in the control in winter. However, the time of onset and blood flow at onset showed no significant relation between groups. 3) The magnitude of reactive hyperemia after a 5 min-arterial occlusion in both air and $15^{\circ}C$ water bath was significantly lower in the ana than in the control. In control subjects, post-occluded blood flow in water was significantly greater than in air, while in the ama it decreased to 1/2 of control values. The time required for the return of blood flow to resting values in the air was faster in the ama than in the control but was the same in water in the two groups. 4) The results suggest that vasoconstrictor tone increased in the ama in winter, indicating the development of vascular adaptation as a part of cold acclimatization.