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초등학교 아동의 비만 진단에 있어서 생체 전기저항 분석법의 의의
최기철,안영준,양은석,박상기,박종,문경래,Choi, Ki-Cheol,Ahn, Young-Jun,Yang, Eun-Seok,Park, Sang-Kee,Park, Jong,Moon, Kyung-Rye 대한소아소화기영양학회 1998 Pediatric gastroenterology, hepatology & nutrition Vol.1 No.1
목 적: 소아 비만의 평가에 이용되는 측정방법들 간의 상관관계와 생체 전기저항 분석법의 유용성을 알아보고자 한다. 대상 및 방법: 1997년 5월부터 7월까지 광주시내 초등학교 남.여 학생 206명을 대상으로 하여 신장, 체중, 허리둘레, 둔부둘레, 피지두께를 계측한 후, 생체전기저항 법에 신체조성을 측정하여 각 측정방법들 간의 상관관계를 비교하였다. 피지 두께치로 계산한 체지방률과 생체전기저항 법으로 측정한 체지방률의 상관관계를 비교 분석하였다. 결 과: 1) 남아에서 비만 측정방법들 간의 상관 관계; 상완 배측부 피지두께는 체질량 지수(r=0.74)와 가장 높은 상관관계가 있었고, 다음으로 체지방률(r=0.59)과 높은 상관관계가 있었으며 체중, 뢸러지수, 체지방량 순서로 비교적 높은 상관 관계가 있었다. 허리/둔부의 둘레 비, 신장, 체지방체중과는 낮은 상관 관계가 있었다(p<0.001). 견갑골하부 피지두께는 체질량 지수(r=0.64)와 가장 높은 상관관계가 있었으며 뢸러 지수, 체중, 체지방률, 체지방량 순서로 비교적 높은 상관관계가 있었으나(p<0.001), 허리/둔부의 둘레비, 신장, 체지방체중 등과는 낮은 상관관계가 있었다(p<0.01). 생체전기저항법으로 측정한 체지방률은 체질량지수(r=0.62)와 가장 높은 상관관계가 있었으며 상완 배측부 피지두께, 뢸러 지수, 체지방량, 견갑골하부 피지 두께, 체중의 순서로 비교적 높은 상관관계가 있었다(p<0.001). 제지방체중, 신장과는 유의한 상관관계가 없었다. 2) 여아에서 비만 측정방법들 간의 상관관계; 상완 배측부 피지두께는 체질량 지수와 가장 높은 상관관계가 있었고(r=0.70), 다음으로 체중, 제지방체중, 신장, 체지방률 순서로 높은 상관 관계가 있었다(p<0.001). 그러나 뢸러 지수, 허리/둔부의 둘레 비, 체지방량과는 상대적으로 낮은 상관 관계가 있었다(p<0.05). 견갑골하부 피지두께는 체질량 지수, 체중, 제지방체중의 순서로 비교적 높은 상관관계가 있었으며(p<0.001), 뢸러 지수, 신장과는 낮은 상관관계가 있었다(p<0.01). 그러나 체지방률, 허리/둔부 둘레 비, 체지방량과는 유의한 상관관계가 없었다. 생체전기저항법으로 측정한 체지방률은 체질량지수, 뢸러지수, 상완 배측부 피지두께와의 순서로 비교적 높은 상관관계를 보였으며(p<0.001), 체지방량, 체중과는 상대적으로 낮은 상관 관계를 보였다. 그러나 견갑골 하부 피지두께, 신장, 제 지방체중, 허리/둔부의 둘레 비와는 유의한 상관 관계가 없었다. 3) 생체전기저항 법과 피하지방 두께치에 의한 체지방률; 피지두께로 계산한 체지방률과 생체 전기저항 법으로 측정한 체지방률은 유의한 상관 관계가 있었으며(p<0.01), 특히 여아보다 남아에서 더 높은 상관관계가 있었다. 결 론: 피지두께치 및 생체전기저항 법으로 측정한 체지방률을 소아의 비만 판정 및 추적 관찰에 유용하게 사용할 수 있다. Purpose: The purpose of our study is to provide useful information for me-asurement methods of childhood obesity and to provide clinical significance of bioelectrical impedance analysis. Methods: We measured height, weight, waist to hip ratio, skinfold thickness and bioelectrical impedance from 206 elementary students in Kwangju from May to July 1997. Results: In males; 1) There were statistically high correlations between tri-ceps skinfold thickness and body mass index (BMI), percentage of body fat (%BF), weight, Rohler index (RI), total fat weight (TFW), waist to hip (W/H) ratio, height, lean body mass (LBM) (all, p<0.001). 2) There were statistically high correlations between subscapular skinfold thickness and BMI, RI, weig-ht, %BF, TBW (all, p<0.001). 3) There were statistically high correlations between %BF and BMI, triceps skinfold thickness, RI, TFW, subscapular skinfold thickness, weight (all, p<0.001). In females; 4) There were statistically high correlations between triceps skinfold thickness and BMI, weight, LBM, height, %BF (all, p<0.001). 5) There were statistically significant correlations between subscapular skinfold thickness and BMI, weight, LBM, RI, height. 6) There were statistically high correlations between percentage of body fat and BMI, RI, triceps skinfold thickness. The percentage of body fat according to the bioelectrical impedance analysis highly correlated with that calculated by skinfold thickness in males (r=0.57, p<0.01) and in females (r=0.30, p<0.01). Conclusion: The results of our study suggests that bioelectrical impedance analysis is a useful method of estimating body fat in the childhood obesity.
김기영(Ki Young Kim),정택균(Taek Kyun Jeong),정권(Kwon Jung),하정훈(Jeong Hoon Ha),이성철(Seong Cheol Lee),김수완(Soo Wan Kim),김남호(Nam Ho Kim),최기철(Ki Chul Choi),강영준(Young Joon Kang) 대한내과학회 1998 대한내과학회지 Vol.54 No.4
N/A Objectives: The peritoneal equilibration test(PET) is routinely performed in adults treated with chronic peritoneal dialysis to assess the peritoneal transport rate and to optimize treatment prescription. This study focuses on the evaluation of characteristics of peritoneal solute transport rates and physical and serological factors affecting peritoneal transport rate performed in our continuous ambulatory peritoneal dialysis(CAPD) patients due to guide adequate peritoneal dialysis form. Methods: We analyzed 95 PET results which had been tested on the 28th day of CAVD and physical and serological values, such as age, sex, diabetes mellitus, height, weight, body surface area, arterial blood pressure, blood urea nitrogen, creatinine, glucose, cholesterol, triglyceride, total protein, albumin, hematocrit, hemoglobin, sodium, potassium, phosphate which had been obtained on the day of PET. Results: 1) According to transport rate, high transport rate group was 9 cases(9.5%), high average transport group 26 cases(27.4%), low average transport rate group 32 cases(33.6%), and low transport rate group 28 cases (29.5%) respectivly. 2) The average of 4hour D/Pcr was 0.60, 4hour D/Do glucose was 0.46, and drain volume was 2480ml. Thus the average of peritoneal solute transport rate of total patients was low average transport rate. 3) Factors affecting peritoneal solute transport rate were age, body surface area, plasma albumin, serum creatinine and triglyceride level. Conclusion: These findings suggest that high dose peritoneal dialysis form should be used in our CAPD patients because most of them have low average peritoneal transport rate, and age, body surface area, plasma albumin, serum creatinine, and triglyceride level should be considered when select the adequate peritoneal dialysis form.
Mycolasma pneumoniae 감염에 의한 뇌경색증 1례
안영준,최기철,양은석,박영봉,박상기,문경래,김영숙,Ahn, Young Joon,Choi, Ki Cheol,Yang, Eun Seok,Park, Yeong-Bong,Park, Sang-Gi,Moon, Kyung Rye,Kim, Young Sook 대한소아감염학회 1998 Pediatric Infection and Vaccine Vol.5 No.2
Mycoplasma pneumoniae infection is usually confined to the respiratory tract but it can cause a variety of extrapulmonary manifestations such as rashes, myalgia, hemolytic anemia, cerebral infarction, transverse myelitis, cerebellar ataxia, Guillain-Barre syndrome and meningoencephalitis. Neurologic complications of Mycoplasma pneumonia have been rarely reported until now. Cerebral infarction as a complication of mycoplasma infection in children has been very rarely reported. In our case, in a young girl with M. pneumoniae infection, a cerebral infarct resulted in persistent and significant neurological dysfunction. We report a 11-year-old girl with cerebral infarction associated with clinical and serologic evidence of Mycoplasma infection.
권형철(Hyoung Cheol Kwon),김정수(Jung Soo Kim),최기철(Ki Chul Choi),최동성(Dong Seong Choi),송창원(Chang Won Song) 대한방사선종양학회 1994 Radiation Oncology Journal Vol.12 No.3
Purpose : To investigate the effect of aqueous extract of Ganoderma lucidum(G.I.) on the survival of tumor cells in vitro and on the growth of tumors in vivo. Materials and Methods : Dried G.I. was made into powder extracted with distilled water filtered and diluted from a maximum concentration of 100mg/ml in sequence. The cytotoxicity of G.I. in vitro was evaluated from its ability to reduce the clonogenicity of SCK tumor cells. For the tumor growth delay study, about 2X10⁵ of SCK tumor cells were subcutaneously inoculated in the legs of a/J mice. The first experimental group of mice were injected i.p. with 0.2ml of 250mg/kg of G.I. from the first day after tumor inoculation for 10 days. The second experimental group of mice were injected i.p. with 0.2ml of 250mg/kg of G.I. either once a day for 10 days or twice a day for 5 days beginining from the 7th day after tumor inoculation Results : 1. Cytotoxicity in vitro; survival fraction, as judged from the curve, at G.I. concentration of 0.5, 1, 5, 10, 25, 50 and 100mg/ml were 1.0, 0.74±0.03, 0.18±0.03, 0.15±0.02, 0.006±0.002, 0.015 and 0.0015 repectively. 2. Tumor growth delay in vivo; a) the time required for the mean tumor volume to grow to 1,000mm³ was 11days in the control group and 14days in the experimental group. b) the time required for tumor volume to increase 4 times was 11 days in the control group while it was 10,5 and 12 days in the groups injected with G.I. once a day and twice a day from the 7th day after tumor inoculation respectively. Conclusion : Aqueous extracts of G.I. showed a marked cytotoxicity on the SCK mammary cells in vitro. Tumor growth delay was statistically significant when G.I. injection was started soon after tumor inoculation but it was not significant when injection was started after the tumors were firmly established.