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Correlation between Acupuncture Stimulation and Cortical Activation - Further Evidence
조장희,김경요,김형균,이병렬,강창기,나창수,Cho, Zang-Hee,Kim, Kyung-Yo,Kim, Hyeong-Kyun,Lee, Byung-Ryul,Wong, E.K.,Kang, Chang-Ki,Na, Chang-Su The Korean Acupuncture Moxibustion Medicine Societ 2001 대한침구의학회지 Vol.18 No.3
목적 : 이 실험의 목적은 경혈에 대한 침자극이 대뇌피질에 어떠한 영향을 미치는가에 대하여 체계적이고 객관적으로 증명하는 것이다. 방법 : 시각과 관련이 있는 광명(GB37), 청각과 관련이 있는 협계(GB43) 및 외관(SJ5)을 자극하고 fMRI를 통하여 대뇌피질의 활성정도를 관찰하였다. 결과 : 이들 경혈의 자극으로 시각과 청각과 관련된 피질의 활성이 나타났다. 자극에 의한 대뇌피질 활성을 fMRI를 통하여 고찰한 결과 특정한 경혈의 자극이 대뇌피질을 활성화시킨다는 사실을 알 수 있었다. 결론 : 치료 효과는 그 경혈의 자극에 의한 대뇌피질의 활성과 관련이 있음을 말하는 것으로, 경혈지극과 대뇌와의 상관성을 증명하는 것이다.
침의 진통효과: 체성감각신경자극으로 유도된 진통작용에 대한 기능성자기공명영상장치를 이용한 연구
조장희,황선출,손영돈,강창기,배선준,이언정,성강경,박태석,김영보,민훈기,Cho, Zang-hee,Hwang, Seon-chool,Son, Young-don,Kang, Chang-ki,Wong, Edward K.,Bai, Sun-joon,Lee, Un-jung,Sung, Kang-kyung,Park, Tae-seok,Kim, Young-bo,Min, Hoon 대한침구의학회 2004 대한침구의학회지 Vol.21 No.2
Objective : Physiological evidence regarding acupuncture's effect in human patients is not yet well established, despite considerable evidence for its therapeutic efficacy. Besides target or disease specificity of acupuncture, acupuncture analgesia (AA) appears to be another large subclass that poses many questions, such as whether there is point specificity with respect to which acupoint is most effective for a particular condition. Methods : We observed brain activation with functional magnetic resonance imaging (fMRI) using a set of stimuli that consist of pain, pain following Meridian acupuncture, and pain following Sham acupuncture. Results : Among the new observations, the most interesting fact is that data sets of both Meridian acupuncture and Sham acupuncture show decreased activation of the same brain areas related to the pain processing signals. Present functional MRI study demonstrate two important biological observations that could elucidate AA mechanism in human participants: the effects of acupuncture occur through mediation of the higher brain areas. Sham acupuncture stimulation appears to be almost as effective as traditional Meridian acupoint stimulation, suggesting that acupuncture is not entirely point specific. Decreased activation in the limbic paleo cortical areas appears to be the probable neurological manifestation of AA and strongly implies that acupuncture stimulation inhibits the transmission of ascending pain signals to the higher cortical areas by the previously known descending pain inhibitory circuit. Conclusion : We, therefore, a hypothesized that this pain inhibitory circuit is initiated and mediated via the broad sense Hypothalamus Pituitary Adrenal (BS HPA) axis in conjunction to the "sensory stimulation."
간장 및 담도 : 간종괴의 (肝腫塊) 자기공명영상 ( 磁氣共鳴影像)
윤용범(Yong Bum Yoon),송인성(In Sung Song),김정룡(Chung Yong Kim),최병인(Byung Ihn Choi),한만청(Man Chung Han),김주완(Chu Wan Kim),박현욱(Hyun Wook Park),조장희(Zang Hee Cho) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.2
N/A Seventeen liver masses including eight hepatocellu]ar carcinomas, eight hemangiomas and one simple cyst were studied by magnetic resonance imaging (MRI) with 2.0 Tesla superconductive magnet in order to evaluate the possibility of differential diagnosis between the liver masses by MRI and to analyze the optimal pulse sequence in high field magnet. Identical multislice/multiecho techniques were used in all patients of obtain Tl-and T2-weighted spin echo using TR 500, 1500, 2000 msec and TE 30, 60, 90, 120 msec. MRI could detect liver mass in all cases. Hepatocellular carcinoma tended to have ill-defined margin, inhomogeneous signal intensity, central high signal intensity area and capsule sometimes and showed iso- or high signal intensity on SE 500/30 images and high signal intensity on T2 weighted images obtained with 2000 msec TR and 30, 60, 90 msec TE. Hemangioma tended to have sharp margin, homogeneous signal intensity and no central high signal intensity area or capsule and showed iso- or low signal intensity on SE 500/30 images. Hemangioma also has high signal intensity with prolongation of TR and TE. On T2-weighted images obtained with 2000 msec TR and 60, 90, 120 msec TE, hemangiomas had significantly greater contrast between mass and surrounding liver than hepatocel]ular carcinoma. Simple cyst showed well-marginated homogeneous low signal intensity on SE 500/30 image and increased signal intensity with prolongation of TR and TE. Differentiaion between hemangioma and hepatocellulor carcinoma could possible in 17 cases and MRI may become the procedure of choice for distinguishing hemangioma from hepatocellular carcinoma and may replace the angiography for the diagnosis of hemangioma.