Fe계 나노결정 분말코아의 연자성특성에 미치는 입도제어 및 바인더 첨가의 영향

조은경,조현정,권훈태,조은민,류혁현,손근용,박원욱,Cho E.K.,Cho H.J.,Kwon H.T.,Cho E.M.,Ryu H.H.,Sohn K.Y.,Park W.W. 한국분말야금학회 2006 한국분말재료학회지 (KPMI) Vol.13 No.4

The amorphous $Fe_{73}Si_{16}B_7Nb_3Cu_1$ alloy strip was pulverized to get a flake-shaped powder after annealing at $425^{\circ}C$ for 90 min and subsequently ground to obtain finer flake-shaped powder by using a ball mill. The powder was mixed with polyimide-based binder of $0.5{\sim}3wt%$, and then the mixture was cold compacted to make a toroidal powder core. After crystallization treatment for 1 hour at $380{\sim}600^{\circ}C$, the powder was transformed from amorphous to nanocrystalline with the grain size of $10{\sim}15nm$. Soft magnetic characteristics of the powder core was optimized at $550{\sim}600^{\circ}C$ with the insulating binder of 3wt%. As a result, the powder core showed the outstanding magnetic properties in terms of core loss and permeability, which were originated from the optimization of the grain size and distribution of the insulating binder.

변형성장인자-${\beta}_1$이 치주인대세포와 치은섬유아세포의 증식에 미치는 영향

조은경,이재목,서조영,Cho, Eun-Kyeung,Lee, Jae-Mok,Suh, Jo-Young 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.3

미분화중배엽세포의 분화에 관여한다고 알려진 변형성장인자-${\beta}1$이 초기배양한 치주인대세포와 치은섬유아세포에 각기 다른 농도와 시간에 따라 변형성장인자-${\beta}1$을 주입했을때 두 세포의 세포증식능에 미치는 영향을 알아보고 각 조건에 따른 두 세포간의 증식능을 상호 비교해 보고자 본 실험을 실시하였다. 교정치료를 목적으로 내원한 환자의 제 1 소구치 부위의 정상치은을 절제하고, 건강한 제 1 소구치를 발거하여 치은섬유아세포와 치주인대세포를 분리, 배양하여 변형성장인자-${\beta}1$을 주입시키지 않은 군을 대조군으로 하고, 변형성장인자-${\beta}1$을 각각 0.25, 0.5, 1, 2.5, 5ng/ml로 주입시킨 군을 실험군으로하여 24시간, 48시간, 72시간 동안 배양하였으며, 각 시간별 배양 24시간 전에 $1{\mu}Ci/ml$ $[^3H]-thymidine$을 첨가하여 $[^3H]-thymidine$이 DNA내로 편재되는 속도로써 두세포군의 증식능을 측정하여 다음과 같은 결과를 얻었다. DNA합성능에 미치는 변형성장인자-${\beta}1$의 효과는 치주인대세포와 치은섬유아세포 모두에서 투여한 변형성장인자-${\beta}1$의 효과는 치주인대세포와 치은섬유아세포 모두에서 투여한 변형성장인자에 대하여 농도의존적으로 세포가 증식 하는 것으로 나타났다. 치은섬유아세포에 변형성장인자-${\beta}1$을 투여한 군에서는 24, 48, 72시간 모두에서 각 대조군에 비하여 농도의존적으로 증가하는 경향을 보였다. 24시간 적용시 대조군에 비해 1,2.5, 5 ng/ml투여군에서 통계적으로 유의한 차이(P<0.05)를 나타내었고, 48시간 적용시에는 대조군에 비해 1, 2.5, 5 ng/ml 투여군에서 통계적으로 유의한 차이(P<0.05)를 나타내었다. 48시간 적용시에 가장 높은 증식능을 보였으며 72시간 적용시에는 48시간 적용에 비해 전반적으로 증식능이 감소하는 경향을 보였다. 치주인대세포의 DNA 합성능에 미치는 변형성장인자-${\beta}$의 효과는, 변형성장인자-${\beta}$를 각각 24시간, 48시간 적용하였을?? 각 대조군에 비하여 농도의존적으로 증가하는 경향을 보였으며, 24시간 적용시에 대조군에 비해 1, 2.5, 5ng/ml 투여군에서 통계적으로 유의한 차이(P<0.05)를 나타내었고, 48시간 적용시에 대조군에 비해 2.5, 5ng/ml 투여군에서 통계적으로 유의한 차이(P<0.05)를 나타애었다. 72시간 적용시에는 5ng/ml의 농도에서 증식능이 감소하는 경향을 보였다. 48시간 적용시에 역시 가장 높은 증식능을 보였으며 72시간 적용에서는 48시간 적용에 비해 전반적으로 증식능이 감소되는 경향을 나타내었다. 변형성장인자-${\beta}1$의 적용에 따른 치주인대세포와 농도별 비교에서 치은섬유아세포군이 치주인대세포군보다 더 높은것으로 나타났다. The use of transforming growth $factor-{\beta}1$ which functions as a potent biologic mediator regulating numerous activities of wound healing has been suggested for the promotion of periodontal regeneration. The mitogenic effects of transforming growth $factor-{\beta}1$ on human periodontal ligament cells and human gingival fibroblasts were evaluated by determining the incorporation of $[^3H]-thymidine$ into DNA of the cells dose-dependently. Cells were prepared with primary cultured fibroblasts and periodontal ligament cells from humans, and used in experiments were the fourth or sixth subpassage. Cells were seeded with serum free Dulbecco's modified Eagle medium containing 0.1% bovine serum albumine. The added concentrations of transforming growth $factor-{\beta}1$ were 0.25, 0.5, 1, 2.5, 5ng/ml and transforming growth $factor-{\beta}1$ were added to the quiescent cells for 24hours, 48hours, 72hours. They were labeled with lnCi/ml $[^3H]$ thymidine for the last 24hour of the each culture. The results were presented as the mean counts per minute (CPM) per well and S.D. of four determinations. The results were as follows. : The DNA synthetic activity of human gingival fibroblasts was increased dose-dependently by transforming growth $factor-{\beta}1$ at 24 hours, 48 hours and 72 hours. The maximum mitogenic effects were at the 48 hour application of transforming growth $factor-{\beta}1$. The DNA synthetic activity was generally more decreased at the 72 hour application than at the 48 hour the application of transforming growth $factor-{\beta}1$. The DNA synthetic activity of human periodontal ligament cells was increased dose-dependently by transforming growth $factor-{\beta}1$ at 24 hours and 48 hours. But the DNA synthetic activity was decreased at 5ng/ml of the 72 hour application. The maximum mitogenic effects were also at the 48 hour application of transforming growth $factor-{\beta}1$. The DNA synthetic activity of human periodontal ligament cells was generally more decreased at the 72 hour application than at the 48 hour application of transforming growth $factor-{\beta}1$. In the comparision of DNA synthetic activity between the human gingival fibroblasts and human periodontal ligament cells, the human gingival fibroblasts had more activity than the human periodontal ligament cells at all time application with the concentration of transforming growth $factor-{\beta}1$. In conclusion, transforming growth $factor-{\beta}1$ has an important roles in the stimulation of DNA synthesis in human periodontal ligament cells and human gingival fibroblasts, which means an increase in collagen synthesizing cells and thus, may be useful for clinical application in periodontal regenerative procedures.

서울 지역 장염환아에서 분리되는 아데노바이러스 형별

조은경,이규만,정용훈,조양자,김경희,Cho, Eun-Kyung,Lee, Kyu-Man,Chung, Yong-Hoon,Cho, Yang-Ja,Kim, Kyung-Hee 대한소아감염학회 1996 Pediatric Infection and Vaccine Vol.3 No.1

Adenoviruses(Ad) are considered to be second only to rotaviruses as the most significant cause of gastroenteritis in young children in Korea and thus it is essential to know the full spectrum of Ad serotypes routinely present in stool specimens from symptomatic patients. Sixty-six Ad isolates and three questionable ones collected over a 2-year peiord were typed by standard microneutralization, restriction endonuclease digestion and PCR of viral DNA to be able to evaluate these assays comprehensively for their ability to identify Ad associated with gastroenteritis. A total of sixty-one isolates(88.4%) were typed: the predominant types were Ad type 41(Ad41)(26.2%), Ad2(19.7%), Ad40(14.8%), Ad5(9.8%), and Ad7(9.8%) which together accounted for almost 80% of the isolates. The remaining virus isolates were typed as Ad1, 31, 34, 3, 25 and a mixture of 40/41. The incidence of Ad31(4.9%) or Ad3(1.6%) was relatively insignificant. DNA restriction analysis(77.5%) proved to be better than serum neutralization but not so when compared to a PCR-based assay for identification of the enteric Ad serotypes(90%) in stool specimens. In this work, the PCR-based assay was evaluated as a tool for the rapid, yet highly sensitive identification of adenoviral DNA sequences in fresh clinical stool specimens.

고대 동아시아 불탑 구조체계를 통해 본 미륵사지석탑

조은경,박언곤,Cho, Eun-Kyung,Park, Eon-Kon 한국건축역사학회 2011 건축역사연구 Vol.20 No.5

This research was to suggest the types according to structural system of the pagoda in ancient East-Asia and analyze the pagoda to the west of Mireuksaji temple site by these types. It will be possible to understand consistently the relation of the various form of the pagoda. The results of this research were described separately as follows. 1. The Buddhist pagodas founded in the ancient East Asia can be categorized according to their structural system, which provide us with insight to understand the interrelationship of categories. The pagoda is mainly classified into three categories. The first consists of two structures, an internal and an external structure. The second exposes its internal structure to the outside, and the third has the external components changing into the internal ones. 2. Although the pagoda to the west of Mireuksaji Temple Site have an internal and an external structures, it actually solves the structural problem by adopting the masonry structure in the outside as well as in the inside. Especially in this structural consideration can be found in the stylobate and the foundation structure of the pillar. The plan of the pagoda to the west of Mireuksaji Temple Site was intended to reveal the plane of the post-lintel layered construction which has a member, a main pillar, and the inner space in the cube with stones.

파킨슨병 환자의 정량적 뇌파분석 -비선형분석을 이용한 정상인 및 본태성 진전 환자와의 비교

조은경,최병옥,김용재,박기덕,김응수,최경규,Cho, Eun-Kyoung,Choi, Byung-Ok,Kim, Yong-Jae,Park, Ki-Duck,Kim, Eung-Su,Choi, Kyoung-Gyu 대한임상신경생리학회 2006 Annals of Clinical Neurophysiology Vol.8 No.2

Background: Parkinson's disease is movement disorder due to dopaminergic deficiency. It has been noted that cognitive dysfunction also presented on Parkinson's disease patients. But, it is not clear whether such a cognitive dysfunction was a dopaminergic dysfunction or cholinergic dysfunction. Using linear and non-linear analyses, we analysed the effect of cognitive and motor symptom on EEG change. Methods: EEGs were recorded from patients with Parkinson's disease and essential tremor, and normal controls during rest. We calculated the power spectrum, correlation dimension and Lyapunov exponent by using 'Complexity'program. The power spectrum, correlation dimension, and Lyapunov exponent were compared between Parkinson's disease patients and essential tremor patients. Results: Theta power was increased in Parkinson's disease patient group. Correlation dimension was increased in Parkinson's disease patients. Positive correlation was noted between MMSE and correlation dimension, and negative correlation was noted between MMSE and Lyapunov exponent. Lyapunov exponent was decreased in Parkinson's disease patient. Conclusions: We conclude that the state of Parkinson's disease patient is characterized by increased correlation dimension and decreased Lyapunov exponent.

$(ZrO_2)_x-(Tm_2O_3)_y$계의 전기전도도

조은경,정원양,김규홍,조승구,최재시,Eun Kyung Cho,Won Yang Chung,Keu Hong Kim,Seung Koo Cho,Jae Shi Choi 대한화학회 1987 대한화학회지 Vol.31 No.6

$ZrO_2$가 1,3 및 5mol%로 각각 도프된 $(ZrO_2)_x-(Tm_2O_3)_y$계의 전기전도도가 600~1,100$^{\circ}$C 및 $10^{-5}-2{\times}10^{-1}atm$의 산소분압하에서 연구되었다. 전기전도도를 온도의 함수로 도시한 결과, log ${\sigma}$ vs. 1/T의 기울기로 부터 구한 활성화에너지의 평균치는 1.51eV이다. 전기전도도의 산소분압의존성은 두 온도 영역에서 각각 다르며 고온영역에서 ${\sigma}{\alpha}PO_2^{1/5.3}$, 저온 영역에서 ${\sigma}{\alpha}PO_2^{1/10.7}$이다. 전기전도도의 온도 및 산소분압의존성으로 부터 고온영역에서 $(ZrO_2)_x-(Tm_2O_3)_y$계의 결함이 $V_{Tm}^{'''}$이며, electron hole이 전하운반체로 제안되었다. 저온영역에서는 이온과 hole이 전하운반체인 mixed conduction이 가능할 것으로 사료된다. Electrical conductivities of $(ZrO_2)_x-(Tm_2O_3)_y$ systems containing 1, 3 and 5mol% of $ZrO_2$ have been measured as a function of temperature and of oxygen partial pressure at temperatures from 600 to 1,100$^{\circ}$C and oxygen partial pressures from $10^{-5}$ to $2{\times}10^{-1}atm$. Plots of log conductivity vs. 1/T are found to be linear and average activation energy is 1.51 eV. The electrical conductivity dependences on PO$_2$ are different at two temperature regions, indicating ${\sigma}{\alpha}PO_2^{1/5.3}$ and ${\sigma}{\alpha}PO_2^{1/10.7}$ at high-and low-temperature regions, respectively. The defect of $(ZrO_2)_x-(Tm_2O_3)_y$ system is $V_{Tm}^{'''}$ and an electron hole is suggested as a carrier at high temperature region. At low temperature region, a mixed ionic and hole conduction is reasonable.

대두 전처리 공정 및 식물 유래 유산균 혼합 배양에 의한 기능성 유산균 음료 생산기술 개발

조은경 ( Eun Kyung Cho ),조형용 ( Hyung Yong Cho ),김병철 ( Byeong Cheol Kim ),신해헌 ( Hae Hun Shin ),조석철 ( Seok Cheol Cho ),국무창 ( Moo Chang Kook ),변유량 ( Yu Ryang Pyun ) 한국식품영양학회 2011 韓國食品營養學會誌 Vol.24 No.1

This study was conducted to establish process conditions for plant-originated lactic acid production using a mixed culture of plant originated lactic acid bacteria, Lactobacillus sakei B2-16, and Lactobacillus plantarum P23, which were isolated from kimchi, and Bacillus subtilis, which was TP6 isolated from Denjang. Soybean medium was pretreated for 10 minutes at 110℃ and hydrolyzed with 0.2%(w/v) cellulase at 55~60℃ for at least 2 hrs. The quality of the final fermentation product was influenced by the inoculation ratio of the Lactobacillus sakei B2-16, Lactobacillus plantarum P23, and Bacillus subtilis TP6. The optimum microorganism inoculation ratio was 1:0.7:0.3, Lactobacillus sakei B2-16: Lactobacillus plantarum P23: Bacillus subtilis TP6, respectively. The sensory characteristics of the product were a refreshing sourness and a soft flavor.

현대 중국어 부정 초점 표지사 ‘不是’

趙恩瓊(Cho Eun-kyung) 중국어문학연구회 2008 중국어문학논집 Vol.0 No.49

‘Bushi’ is the negative form of the focus marker ‘shi’ in Mandarin Chinese. Instances containing the negative form ‘bushi’ are often described as ‘sentence of refutation’. This paper attempts to show that the negative form ‘bushi’ is used in such a way that it not only signals an objection to a prior utterance but has to be associated with a focused constituent of a sentence. Furthermore this paper attempts to show sometimes ‘bushi’ as negative focus marker is unable to be used as a metalinguistic negation, while ‘bushi’ as contrast negative form enable to be used as a metalinguistic negation.

스트림 제어 전송 프로토콜의 보안에 관한 연구

조은경(Eun Kyung Cho),권영희(Young Hee Kwon) 대한전자공학회 2002 대한전자공학회 학술대회 Vol.2002 No.6

한ㆍ중 항일기념관의 전시 내러티브와 동아시아 역사인식

조은경(Cho, Eun-Kyung) 독립기념관 한국독립운동사연구소 2014 한국독립운동사연구 Vol.0 No.47

이 연구에서는 한국과 중국의 대표적인 항일기념관인 독립기념관과 중국인민항일전쟁기념관을 중심으로 건립과정과 전시 내러티브를 비교검토하고 전시에서 재현된 동아시아 역사인식을 살펴보았다. 두 기념관은 1982년 일본의 역사교과서 파동을 계기로 1987년 건립하였으며 항일투쟁사를 주제로 전시 내러티브가 구성되었다. 이를 통해 일제의 침략만행을 고발하고 민족단결의 통합가치를 강조한다는 점에서 공통된 특성이 있었다. 동아시아 역사인식에 대한 검토 결과 두 기념관 모두 일제의 침략만행을 고발하고 있으나 오늘날 일본에 대한 인식은 차이가 있었다. 독립기념관은 일본의 역사왜곡과 영토분쟁을 규탄한데 반해 항전관은 중일우호관계를 강조하였다. 한국과 중국의 상호인식, 한중공동항일투쟁에 대한 인식은 충분치 않았다. 동북항일연군, 조선의용대(군), 일본군‘위안부’ 등 공통된 전시주제가 확인되었지만 두 기념관 전체 전시 속에서 차지하는 비중이 극히 적고 역사해석에서 차이가 있었다. 두 기념관의 전시 내러티브를 구체적으로 검토해볼수록 양국 간 역사인식차가 더욱 커진 원인은 두 기념관 모두 각국에서 공식적으로 공유되는 집단기억을 전시 내러티브로 삼았기 때문이다. 역사인식의 주체와 목적이 달랐기 때문에 전시되는 내용 또한 다를 수밖에 없었던 것이다. 이는 한국과 중국이 일본제국주의에 의해 피해를 입었고 항일투쟁을 전개한 유사한 역사경험을 했기 때문에 역사인식 또한 크게 다르지 않을 것이라는 예상과는 다른 결과였다. 두 기념관이 한국과 중국에서 차지하는 위상을 염두에 두어볼 때 기념관에서 확인되는 역사인식과 내러티브의 차이는 한·중 양국의 근현대사 인식을 대변한다고 볼 수 있다. 일본의 역사왜곡이 확대 강화되는 현재 독립기념관과 항전관의 역할은 더욱 중요하다. 두 기념관은 철저한 고증을 거쳐 일본의 역사왜곡을 실증적으로 반박하는데 주력해야 할 것이다. 또한 지속적인 교류로 한중 양국의 역사해석을 공유하고 상호 인식을 확대하여 한중 역사공조의 토대가 될 수 있도록 역할을 담당해야한다. 두 기념관의 활동을 통해 동아시아 공동의 역사인식을 형성하고 반침략 평화주의를 후손에게 전승할 수 있기를 기대한다.