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Hidrotic Ectodermal Dysplasia 1 예
조성호,김진택 대한피부과학회 1979 大韓皮膚科學會誌 Vol.17 No.4
Congenital ectodermal dysplasia are a group of familial disorders that affect tissues and organs of ectodermal origin to varying degrees. It devided hidrotic type and anhidrotic type by geneologic origin and distinct clinical manifestationa. The hidrotic type usually trait by autosomal dominant gene and manifested dystrofic nails, defect of hair and eyebrow and palmoplantar hyperkeratosis. This patient is 16 year oId male. He had been dystrophic nails, alopecia since at birth, thereafter palmoplantar hyperkeratosis, clubbing fingers noted. C.B.C. Urinalysis, stool examination, chest x-ray were within normal limit. Biopsy specimen from palm revealed hyperkeratosis, hypergranulosis, acanthosis and, mild inflamrnatory cell infiltrate on upper dermis. Biopsy speeimen from the scalp revealed norrriaI findings except slight hypoplasia of ebaceaus gland.
조성호,정순관 재단법인 경기연구원 2018 GRI 연구논총 Vol. No.
본 연구에서는 합의제 기관구성에 대한 이론적 검토와 선행연구를 검토하여 합의제 기관구성(각료회의, 지방장관제) 도입의 분석틀을 설정하였다. 이러한 합의제 기관구성 도입의 분석틀을 토대로, 경기도의 연합정치에서 추진한ⅰ) 합의제 기관구성의 추진현황, ⅱ) 합의제 기관구성의 실효성 평가, ⅲ) 원활한 합의제 기관구성을 위한 법적·제도적 개편방안을 제시하였다. 경기도는 합의제 기관구성의 추진을 위해, 각료회의 기능으로서 경기도 연정 실행위원회를 설치·운영하였고, 지방장관제 기능으로서 연정위원장제를 도입, 운영하였다. 이러한 경기도의 합의제 기관구성의실효성을 평가하면, 합의제 기관구성의 도입으로 한국정치의 최대 문제점인 승자독식의 정치에서 벗어나 권력공유를통한 화합의 정치를 구현하고 있는 것으로 평가된다. 그러나 지방정부의 합의제 기관구성에 대한 법적·제도적 제약으로, 합의제 기관구성의 효율성이 미약한 것으로 평가되었다. 앞으로 헌법 및 지방자치법 개정을 통하여 지방의 합의제 기관구성을 허용해야 할 것이다. In this study, the analysis of theoretical review and precedent studies on the composition of the consensus system and the analysis framework of the adoption of consensus-making bodies (ministerial meetings, local ministers) were set up. Based on the analytical framework of the introduction of the consensus-based institutional structure, it is suggested that the unified government of Gyeonggi Province should be able to: (i) review the status of the composition of the consensus-based agency; (ii) evaluate the effectiveness of the consensus-based organization; and iii) promote the composition of the consensus system with the help of Gyeonggi-do’s Executive Committee as a function of the ministerial meeting. In order to assess the effectiveness of the Gyeonggi-do Consensus-making Institution, the adoption of the consensus-based institutional structure is considered to be implementing the politics of unity through the sharing of power by escaping from the politics of the winner, which is the biggest problem of Korean politics. However, due to legal and institutional constraints on the composition of the local government, the effectiveness of the consensus-making institution was evaluated to be weak. From now on, the amendment of the Constitution and the Local Autonomy Law should allow the formation of local consensus institutions.
기관절개술 후 발생한 기관무명동맥루에서 연골막을 포함한 늑연골을 이용한 기관성형술 -수술치험 1예-
조성호,조성래,계여곤,김종인 대한흉부외과학회 2007 Journal of Chest Surgery (J Chest Surg) Vol.40 No.9
기관무명동맥루는 매우 드물지만 높은 사망률을 보이는 질환으로, 장기간의 기관절개술이나 기관내 삽관후 합병증으로 발생한다. 대량 출혈로 인해 기도폐쇄 및 출혈성 쇼크로 생명의 위협이 초래되기 때문에 조기 진단과 즉각적인 치료가 반드시 필요하다. 후두 협착에 대한 수술을 위해 가능한 한 기관의 보존이 필요한 환자에 발생한 기관무명동맥루 환자에서 연골막을 포함한 늑연골을 이용한 기관성형술을 시행하였기에 보고하는 바이다.
Normothermic Cardiac Surgery with Warm Blood Cardioplegia in Patient with Cold Agglutinins
조성호,김대현,곽영태 대한흉부외과학회 2014 Journal of Chest Surgery (J Chest Surg) Vol.47 No.2
Cold agglutinins are predominately immunoglobulin M autoantibodies that react at cold temperatures with surface antigens on the red blood cell. This can lead to hemagglutination at low temperatures, followed by complement fixation and subsequent hemolysis on rewarming. Development of hemagglutination or hemolysis in patients with cold agglutinins is a risk of cardiac surgery under hypothermia. In addition, there is the potential for intracoronary hemagglutination with inadequate distribution of cardioplegic solutions, thrombosis, embolism, ischemia, or infarction. We report a patient with incidentally detected cold agglutinin who underwent normothermic cardiac surgery with warm blood cardioplegia.
The Right Ventricular Myxoma Which Attached to the Tricuspid Valve: Sliding Tricuspid Valvuloplasty
조성호,김욱성,심만식 대한흉부외과학회 2015 Journal of Chest Surgery (J Chest Surg) Vol.48 No.3
We report a rare case of an extremely large right ventricular myxoma involving the ventricular side of the tricuspid valve. The tumor was excised along with the entire posterior leaflet and part of the anterior leaflet. The tricuspid valve was repaired by sliding valvuloplasty combined with ring annuloplasty.
Anticoagulant Therapy-Induced Gallbladder Hemorrhage after Cardiac Valve Replacement
조성호,이해영,김현수 대한흉부외과학회 2015 Journal of Chest Surgery (J Chest Surg) Vol.48 No.6
Anticoagulation therapy is essential after cardiac valve surgery. However, spontaneous bleeding remains a major concern during anticoagulation therapy. Spontaneous gallbladder (GB) hemorrhage (hemobilia) is a rare occurrence during standard anticoagulation therapy. This report presents a case of GB hemorrhage that occurred shortly after initiating oral anticoagulant therapy in a patient who had undergone mitral valve replacement surgery.
폐구역절제술로 제거된 기관지 내 연골성 과오종 -수술치험 1예-
조성호,박성달 대한흉부외과학회 2005 Journal of Chest Surgery (J Chest Surg) Vol.38 No.9
In comparison to parenchymal hamartoma, endobronchial hamartoma is rare benign neoplasm of the lung. Most parenchymal hamartomas are asymptomatic and are found incidentally. However, endobronchial hamartomas are frequently discovered through respiratory symptoms as a result of bronchial irritation or obstruction. A 47-year-old male patient was admitted to our hospital due to dry cough 1 month prior to admission. On bronchoscopic examination, a polypoid mass was found completely obliterating the anterior segmental bronchus of the left upper lobe. We report a case of endobronchial chondroid hamartoma, which was resected by anterior segmentectomy of the left upper lobe. 폐실질내 과오종에 비해 기관지 내 과오종은 드문 질환으로 폐실질 내 과오종이 우연히 발견되는것에 비해 기관지 내 과오종은 기관지 폐색에 의한 증상이 유발되어 발견되는 경우가 많다. 47세 남자가 한 달간의 기침을 주소로 내원하였다. 기관지 내시경에서 좌상엽 전구역을 폐쇄하고 있는 과오종이 발견되었으며 좌상엽전구역 절제술로 제거되었다. 저자들은 좌상엽 전구역 절제술로 제거된 기관지내 과오종을 경험하여 보고하는 바이다
조성호,김종인,김현수,박성달,장강원 대한흉부외과학회 2017 Journal of Chest Surgery (J Chest Surg) Vol.50 No.3
Background: The mesenchymal-epithelial transition factor (MET) receptor can be overexpressed in solid tumors, including small cell lung cancer (SCLC). However, the molecular mechanism regulating MET stability and turnover in SCLC remains undefined. One potential mechanism of MET regulation involves the C-terminus of Hsp70-interacting protein (CHIP), which targets heat shock protein 90-interacting proteins for ubiquitination and proteasomal degradation. In the present study, we investigated the functional effects of CHIP expression on MET regulation and the control of SCLC cell apoptosis and invasion. Methods: To evaluate the expression of CHIP and c-Met, which is a protein that in humans is encoded by the MET gene (the MET proto-oncogene), we examined the expression pattern of c-Met and CHIP in SCLC cell lines by western blotting. To investigate whether CHIP overexpression reduced cell proliferation and invasive activity in SCLC cell lines, we transfected cells with CHIP and performed a cell viability assay and cellular apoptosis assays. Results: We found an inverse relationship between the expression of CHIP and MET in SCLC cell lines (n=5). CHIP destabilized the endogenous MET receptor in SCLC cell lines, indicating an essential role for CHIP in the regulation of MET degradation. In addition, CHIP inhibited MET-dependent pathways, and invasion, cell growth, and apoptosis were reduced by CHIP overexpression in SCLC cell lines. Conclusion: C HIP is c apable of regulating SCLC cell apoptosis and invasion by inhibiting MET-mediated cytoskeletal and cell survival pathways in NCI-H69 cells. CHIP suppresses MET-dependent signaling, and regulates MET-mediated SCLC motility.