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Objectives: This study was conducted to investigate the relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) index, waist-to-height ratio (WHtR) which were evaluated as cardiometabolic risk factors and components of heart rate variability (HRV). Methods: This study was conducted on 2,008 subjects who underwent HRV test among those who had health-check up at a university hospital in Korea during 2016. The presence of metabolic syndrome in the subjects was identified. TG/HDL and WHtR were calculated and blood level of leukocyte, erythrocyte, amino transferase, uric acid were used for analysis. Standard deviation of the NN interval (SDNN), low frequency (LF), high frequency (HF), and LF/HF were used for the components of HRV. Results: Among the total subjects, 330 (16.4%) had metabolic syndrome. The mean SDNN in the subjects with metabolic syndrome was 32.78±16.49 (ms), which was significantly lower than that (36.16±18.75 ms) of the control group (p<0.01). The HF values were also significantly different between the two groups (162.77±278.08 ms<sup>2</sup> vs. 225.74±330.99 ms2, p<0.05). Except HDL, waist circumference, blood pressure, fasting blood glucose, and triglyceride concentration among metabolic syndrome components were negatively correlated with SDNN and HF. Significant negative correlations were found in SDNN (p<0.01) and HF (p<0.05) with WHtR and only SDNN (p<0.05) with TG/HDL. Conclusions: TG/HDL and WHtR, including the metabolic syndrome, showed a negative correlation between SDNN indicating left ventricular function and HF indicating activation of parasympathetic nerve.
Objectives: Behaviors of weight control for obesity, which is closely related to all causes death, are affected by the subjective perception of obesity, degree of body mass index (BMI), and the state of multiple chronic diseases. The purpose of this study was to identify factors related to successful weight reduction among subjects who tried to reduce their weight. Methods: This study was conducted using data of the Korea National Health and Nutrition Examination Survey (2015). Among 1,687 subjects who answered “I tried to reduce my weight for 1 years.”, the subjects who answered “I have lost weight” in the question of change in weight were the group of successful weight reduction. We compared gender, demographics, lifestyle, obesity, morbidity, and weight control methods between successful weight reduction group and control group. Results: Two hundreds sixty (15.4%) among total subjects reported successful weight reduction. Young age (odds ratio=1.02, 95% confidence interval=1.00-1.04), aerobic exercise activity (1.36, 1.01- 1.81), subjective perception of obesity (0.68, 0.47-0.97), obesity by BMI (0.62, 0.43-0.89), history of diabetes (2.35, 1.28-4.32) and prescriptive anti-obesity agents (3.44, 1.80-6.57) were associated with successful weight reduction. Conclusions: In order to achieve successful weight reduction, intervention strategies based on this results will be needed.
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고혈압이나 당뇨와 같은 만성질환은 흡연자들에서 금연시도 및 금연유지와 관련된 요인 중 하나이다. 본 연구는 고혈압, 당뇨, 이상지질혈증 등의 만성질환 인지와 금연시도 및 금연유지와의 연관성을 확인하기 위하여 지역사회 건강조사 자료를 이용하여 수행되었다. 평생 흡연력을 가진 19세 이상 성인 남성 76,065명 중 현재 흡연자는 41,509(54.6%)명, 금연자는 34,556(45.4%)명이었다. 현재 흡연자 중 금연 미시도자는 14,206(34.2%)명, 금연 시도자는 27,303(65.8%)명이었다. 평생 흡연력을 가진 성인 남성들 중 고혈압, 고지혈증, 심장질환의 질병력이 있을 때 금연 시도의 교차비는 각각 1.100(95% 신뢰구간, 1.019∼1.187), 1.284(1.173∼1.406), 1.499(1.277∼1.833)이었다. 금연유지에 대해서는 고혈압, 고지혈증, 뇌졸중, 심장질환 질병력이 있는 경우 교차비가 각각 1.364(1.270∼1.465), 1.426(1.306∼1.557), 1.362(1.097∼1.690), 1.590(1.319∼1.915)이었다. 당뇨 병력은 금연 시도 및 금연유지와 관련이 없었다. 향후 금연 상담 시 각각의 만성질환을 가진 흡연자들에서 금연시도 및 유지에 영향을 주는 요인을 확인하고 이를 바탕으로 질환별로 맞춤형 금연중재에 대한 연구를 실시할 것을 제언한다. Chronic diseases as hypertension or diabetes are known to be one of the related factors for quit smoking attempt and smoking cessation. This study was conducted to confirm the association between smoking cessation and chronic diseases such as hypertension, diabetes, and dyslipidemia using community health survey data. There were 41,509 (54.6%) current smokers and 34,556 (45.4%) former smokers among 76,065 who were 19 years old and older male adults with lifetime smoking habits. Among current smokers, 14,206 (34.2%) were no-quit smoking attempt and 27,303 (65.8%) were quit smoking attempt. The odds ratio for quit smoking attempt was 1.100 (95% confidence interval, 1.019 ∼ 1.187), 1.284 (1.173 ∼ 1.406) and 1.499 (1.277 ∼ 1.833), respectively, when the patients were diagnosed with hypertension, dyslipidemia and heart disease. The odds ratios for smoking cessation were 1.364 (1.270 ∼ 1.455), 1.426 (1.306 ∼ 1.557), 1.362 (1.097 ∼ 1.990) and 1.590 (1.319 ∼ 1.915) for hypertension, dyslipidemia, stroke and heart disease. Diabetes was not associated with quit smoking attempt and smoking cessation. Smoking cessation counselors identify the factors for smoking cessation in smokers with chronic diseases. It is suggested to conduct a study on customized smoking cessation intervention for each disease.
문성욱(Sung Uk Mun),전형진(Hyeong Jin Jeon),정기훈(Ki Hoon Jung),하동엽(Dong Yeop Ha),정병욱(Byung Ook Chung),정호근(Ho Geun Jung),안우섭(Woo Sup Ahn),하경임(Gyoung Yim Ha),배종대(Jong Dae Bae),강선희(Seon Hui Kang) 대한외과학회 2007 Annals of Surgical Treatment and Research Vol.72 No.5
Purpose: Central venous catheterization is widely used to supply substantial amounts of fluids, total parenteral nutrition and hemodialysis in renal failure patients, as well as for measuring the central venous pressure. The most common complications encountered during central venous catheterization include catheter-related infections and subsequent sepsis. Therefore, when fever exists in patients with a central venous catheter, an immediate blood culture should be performed, and if the fever persists, an infection must be suspected and the catheter immediately removed; a culture of the catheter tip should also be performed. To date, no definite clinical details relating to this matter have been reported. Methods: Between December 2002 and March 2005, a retrospective study was undertaken using the medical records of 85 patients. In those patients where a fever lasted for more than 8 hours, or when catheterization was no longer needed, the catheter tip cultures were sent to the microbiology laboratory. Blood cultures were also performed on 49 patients with a fever. The Chi-square method using the PC SPSS program, with P value less than 0.05 as statically significant. Results: Of the 85 patients where the catheters were removed, significant microorganisms were detected 20 of the 49 with a fever. Only 5 of the remaining 36 patients had their catheters spontaneously removed. Moreover, 14 of the 20 patients with significant microorganisms were found to have kept their catheter in place for more than 14 days. Of the 49 patients with a fever, in who blood cultures were undertaken, 13 showed specific microorganisms, with 6 of these showing the same results for both their blood and catheter tip cultures, which enabled the definite diagnosis of the catheter-related infection and underlying sepsis. Various microorganisms were detected from the catheter tip cultures, including Staphylococcus species the CNS, with S. aureus being the most common, at 61.6%. Conclusion: A central venous catheter should be removed immediately when an infection is suspected, but early broad-spectrum antibiotics therapy should be commenced due to the time required to obtain the culture results. Moreover, even if a fever does not exist in patients with a catheter inserted for more than 14 days, infection and sepsis from the catheter should be of concern, with a more cautious approach being mandatory.
Purpose: Carcinoembryonic antigen (CEA) is the most widely used tumor marker for detecting colorectal cancer. This study was designed to evaluate the level of serum CEA that is associated with recurrence after potentially curative surgery for colorectal cancer. Methods: We retrospectively investigated the pre- and post-operative levels of serum CEA in 246 patients with colorectal cancer and they had undergone potentially curative surgery from 1996 through 2005. Results: The pre-operative CEA level was significantly associated with the number of metastatic lymph nodes, the tumor size and the recurrence rate. The feature that was associated with recurrent disease on multivariate analysis was the pre-operative level of serum CEA. Conclusion: In order to detect the recurrence of colorectal cancer, we should closely follow up with frequent checks of the CEA level after surgery for those patients who had a high preoperative CEA level.