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투석용 동정맥루의 개통율과 이에 영향을 주는 인자의 분석: 자가혈관 동정맥루와 인조혈관 동정맥루의 비교, 단일기관 연구
정혜원 ( Hae Won Jung ),임영환 ( Young Hwan Lim ),이유지 ( Yu Ji Lee ),강나리 ( Na Ree Kang ),이정은 ( Jung Eun Lee ),허우성 ( Woo Seong Huh ),오하영 ( Ha Young Oh ),김윤구 ( Yoon Goo Kim ),김대중 ( Dae Joong Kim ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.1
목적: 당뇨병과 고령의 환자들이 증가함에 따라 인조혈관을 이용한 동정맥루 수술이 점차 증가하고 있다. 그러나 자가혈관 동정맥루와 인조혈관 동정맥루의 개통율의 비교에 대한 국내 자료는 미미한 실정이다. 저자들은 자가혈관 동정맥루와 인조혈관 동정맥루의 개통율을 비교하고, 동정맥루의 개통율에 영향을 미치는 인자에는 어떤 것들이 있는지 알아보고자 하였다 방법: 2003년 1월 1일부터 2003년 12월 31일까지 대학병원에서 자가 또는 인조혈관 동정맥루 수술을 받은 환자들을 대상으로 후향적 연구를 진행하였다. 동정맥루의 일차, 이차 개통율을 분석하였고, 개통율에 관련된 인자를 성별, 연령 및 기저 질환을 보정하여 분석하였다. 또한 일차 혈로 부전 발생율도 조사하였다. 결과: 2003년에 총 196건의 동정맥루 수술이 시행되었다. 이중 추적 되지 않은 14건을 제외한 182건을 대상으로 연구를 진행하였다. 자가혈관 동정맥루 수술은 142건 (78%)이었고, 인조혈관 동정맥루 수술은 40건 (22%)이었다. 수술 후 일차 혈관 부전 발생율은 자가혈관 동정맥루와 인조혈관 동정맥루 사이에 통계적으로 차이가 없었다. 일차 개통율 (1, 2, 3년 째 78%, 72%. 68% vs. 62%, 41%, 22%; p<0.001)과 이차 개통율 (1, 2, 3년 째 93%, 88%, 85% vs. 84%, 74%, 73%; p=0.087)은 자가혈관 동정맥루가 인조혈관 동정맥루보다 우수하였다. 동정맥루의 종류와 계획된 수술로 만들었는지 여부가 동정맥루의 개통율에 영향을 미치는 인자였다. 결론: 자가혈관 동정맥루가 인조혈관 동정맥루보다 개통율이 우수하였다. 또한 계획적으로 만들어진 혈관 통로일수록 개통율이 우수하였다. Purpose: As the proportion of patients with diabetes and old age increases, the use of arteriovenous graft (AVG) is increasing. However, there are few data about the comparison of the patency rate of native arteriovenous fistula (AVF) to that of AVG in Korea. We compared the outcome of native AVF to that of AVG with analysis of the factors affecting the patency of the permanent vascular access in use. Methods: A retrospective database of all vascular access related procedures performed from January 1, 2003 to December 31, 2003 was established. We evaluated the primary unassisted and cumulative access patency rate with analysis of patency-related factors. We also evaluated the primary failure rate of AVF and AVG. Results: 196 new vascular access surgeries were performed during the period. 14 cases were excluded due to loss of follow-up. 142 native arteriovenous fistulas (78%) and 40 grafts (22%) were constructed. The primary failure rate was similar between AVF and AVG group. The primary unassisted (78%, 72%, 68% vs. 62%, 41%, 22% at 1, 2, 3 year; p<0.001) and cumulative patency rate (93%, 88%, 85% vs. 84%, 74%, 73% at 1, 2, 3 year; p=0.087) were better in AVF group than in AVG group. The factors affecting the patency of vascular access were the type of vascular access and planned construction of permanent vascular access. Conclusion: Patency of native AVF as the permanent vascular access was better than that of AVG. Planned construction of permanent vascular access improved the patency of the access.
Severely Active Class 4 Lupus Nephritis: the Prognostic Significance to Clinical Outcome
정혜원 ( Hae Won Jung ),오하영 ( Ha Young Oh ),김대중 ( Dae Joong Kim ),김윤구 ( Yoon Goo Kim ),이정은 ( Jung Eun Lee ),고은미 ( Eun Mi Koh ),차훈석 ( Hoon Suk Cha ),서진원 ( Jin Won Seo ),권기영 ( Gee Young Kwon ),허우성 ( Woo Se 대한신장학회 2008 춘계학술대회 초록집 Vol.28 No.1
증례 : 심한 증식성 루푸스 신염과 혈전성 혈소판 감소성 자반증이 병발한 남성 환자에서 cyclophosphamide 치료 경험 1예
정혜원 ( Hae Won Jung ),신준암 ( Jun Am Shin ),이유지 ( Yu Ji Lee ),강나리 ( Na Ree Kang ),권기영 ( Ghee Young Kwon ),한봉준 ( Bong Jun Han ),김윤구 ( Yoon Goo Kim ) 대한내과학회 2006 대한내과학회지 Vol.71 No.2
TTP가 병발한 SLE에서 조기에 신선 냉동 혈장 투여와 혈장 교환술을 적극적으로 시행해야 한다. 이러한 적극적인 초기 치료에도 불구하고 병이 진행하거나, 루푸스 신염이 동반된 경우에 cyclophosphamide의 병합 요법이 치료에 도움이 됨을 저자들은 경험하여 보고하는 바이다. Thrombotic thrombocytopenic purpura is a rare but fatal complication of systemic lupus erythematosus. The diagnosis of thrombotic thrombocytopenic purpura as a syndrome distinct from systemic lupus erythematosus may be challenging particularly when thrombotic thrombocytopenic purpura is presented concomitantly with systemic lupus erythematosus. Early diagnosis and aggressive treatment including plasmapheresis would be required. However, recent reports have suggested that the use of cyclophosphamide may have a role. We describe a patient with systemic lupus erythematosus who was first presented with severe thrombotic thrombocytopenic purpura. Diagnosis was based on typical clinical features of thrombotic thrombocytopenic purpura and laboratory findings of active lupus nephritis. Renal biopsy also confirmed the coexistence of thrombotic thrombocytopenic purpura and diffuse proliferative lupus nephritis. Although prompt extensive plasmapheresis and high dose steroid therapy were performed, oliguric renal failure and thrombocytopenia persisted. After addition of cyclophosphamide to the treatment with plasmapheresis and steroid, clinical manifestations of thrombotic thrombocytopenic purpura and lupus nephritis were markedly improved. (Korean J Med 71:214-218, 2006)
여성 결혼이민자의 양육 스트레스와 자기효능감 수준에 따른 PPAT 그림검사 반응 특성
정혜원 ( Jung Hye-won ),박성혜 ( Park Sung-hae ) 한국미술심리치료연구학회 2023 미술심리치료연구 Vol.2 No.2
본 연구는 여성 결혼이민자의 양육 스트레스와 자기효능감 수준에 따른 PPAT 그림검사 반응 특성을 분석하여 여성 결혼이민자의 심리 진단 및 양육 스트레스와 자기효능감을 예측하는 보완 도구로서 PPAT 그림검사의 활용 가능성을 알아보고자 하였다. 이에 인천광역시에 거주하는 여성 결혼이민자 155명을 대상으로 양육 스트레스와 자기효능감 수준을 측정하고 PPAT 그림검사를 시행하였다. 본 연구에서 밝혀진 결과를 요약하면 다음과 같다. 첫째, 여성 결혼이민자의 양육 스트레스와 자기효능감 간의 상관분석을 실시한 결과 양육 스트레스와 자기효능감 간에는 부적 상관이 나타났다. 둘째, 여성 결혼이민자의 양육 스트레스 상·하위집단 간에 PPAT 그림검사에 대한 반응 특성 차이를 검증한 결과 형식척도 항목 중 공간, 논리성, 선의 질, 사람, 회전에서 유의한 차이가 검증되었다. 내용척도에서는 사람에 사용된 색의 수, 인물의 실제에너지 ‘사과에 손을 뻗은’, 인물의 얼굴 방향 ‘뒷면’, 환경과 세부묘사 ‘새’에서 유의미한 차이가 있었다. 셋째, 여성 결혼이민자의 자기효능감 수준에 따른 PPAT 그림검사에 대한 반응 특성 차이를 검증한 결과형식척도 항목 중 내적에너지, 문제해결력에서 유의한 차이가 검증되었다. 내용척도에서는 인물의 성별 ‘평가 못 함, 여성’, 인물의 얼굴 방향 ‘뒷면’, 인물의 나이 ‘유아 아동’, 사과나무, 환경과 세부묘사 ‘꽃, 울타리’에서 유의미한 차이가 있었다. 본 연구는 여성 결혼이민자의 양육 스트레스와 자기효능감 간의 관계에서 PPAT 그림검사 반응 특성 차이를 검증하였고, 이를 통해 PPAT 그림검사가 여성 결혼이민자의 심리진단 및 양육 스트레스와 자기효능감을 예측하는 보완 도구로 활용될 수 있음을 확인하였다. The purpose of this study is to investigate the applicability of the PPAT test as a supplementary tool for psychological diagnosis and for predicting parenting stress and self-efficacy of female marriage immigrants by analyzing the PPAT response characteristics depending on parenting stress and self-efficacy level. Parenting stress and self-efficacy levels were examined and the PPAT test was conducted for 155 female marriage immigrants living in Incheon Metropolitan City. The result of this study is as follow. First, a correlation analysis of parenting stress and self-efficacy in female marriage immigrants indicated a negative correlation between the two. Second, significant differences in space, logic, line quality, person, and rotation in terms of the formal elements art therapy scale were verified as a result of examining the difference in response characteristics to the PPAT test between the group with high parenting stress and the group with low parenting stress among female marriage immigrants. In terms of content scale, there were significant differences in color used for person, actual energy of the person ‘reaching out for the apple’, the face direction of the character ‘back’ and the description of environment and detail ‘animal-bird’. Third, substantial disparities in implied energy and problem-solving were verified in terms of the formal elements art therapy scale as a result of studying the difference in response characteristics to the PPAT depending on the self-efficacy level of female marriage immigrants. There were significant differences in the gender of the character, the character’s face orientation ‘back side’, age, apple tree, and the description of environment and detail ‘flower, fence’ on the content scale. This study validated the difference in response characteristics of the PPAT test in the association between parenting stress and self-efficacy of female marriage immigrants, and the findings suggest that the PPAT could be used as a complementary tool for psychological diagnoses and predicting parenting stress and self-efficacy in female marriage immigrants.
한호정 ( Ho Jung Han ),정혜원 ( Hae Won Chung ) 한국의류학회 2014 한국의류학회지 Vol.38 No.6
Winter outerwear includes various clothes such as classical jackets/coats, padded jackets/coats, wind breakers, leather and fur jackets/coats. This research surveyed care-label instructions attached to 100 jackets/coats dropped off at five drycleaners in the Gyungin area. University students`` perception and attitudes towards care labels and management of winter outerwear were examined using a questionnaire. Data collected from230 respondents were analyzed by frequency analyses, t-tests, ANOVAs and Duncan tests with PASW20.0. Half of the padding jackets/coats were labelled to be dry cleaned and dry cleaning was more excessivelylabelled than necessary. University students confirmed more care symbols than fiber compositions such as more at time of cleaning than at purchasing. Clothing-related major students understood care label symbols better than non-clothing major students. Consumers laundered some winter outerwear at home, even though they thought dry cleaning was a proper cleaning method. The appropriate cleaning method for padded jackets/coats is laundering; however, consumers who answered dry cleaning as an appropriate method were three times as those who answered washing, and those performed dry cleaning were two times as those who performed washing. Winter outerwear manufacturers should provide adequate and more specified care-information to consumers in order to maintain initial appearance and performance over longer periods.
한선남,김향미,정혜원,오승은,손영수,유한기,안정자,우복희,Han, Sun-Nam,Kim, Hyang-Mee,Jung, Hae-Won,Oh, Seung-Eun,Son, Young-Soo,Yu, Han-Ki,Ahn, Jung-Ja,Woo, Bock-Hee 대한생식의학회 1993 Clinical and Experimental Reproductive Medicine Vol.20 No.2
These studies were carried out to investigate the optimal freezing protocol for 2 cell mouse embryos and to find the probability of quality control with 2-cell embryos frozen. The embryos showed the best survival by the protocol composed of a freezing solution with the cryoprotectants(1.5M propanediol + 0.1M sucrose), and a 2-steop thawing method(room temperature, 20 sec-37$^{\circ}C$, 20 sec). The developmental ability of frozen-thaw 2-cell embryos did not differ from that of fresh 2-cell embryos in m-KRB medium with 0.4% bovine serum albumin. But development of frozen-thaw embryos was depended on the supplements of the medium. In the albumin-free medium, the developmental rate(rate of blastocysts) was significantly reduced, compared with that in the medium with 0.4% BSA. Also, when frozen-thaw embryos were cultured in the meduim with human fetal cord serum(HCS), the developmental rate of frozen-thaw embryos was sligtly reduced, compared with that of fresh 2-cell embryos. Finally, frozen-thaw 2-cell mouse embryos were more sensitive to the toxic agent of disposable-plastic syringe. Therefore, toxicity of medium could be effectively detected by frozen-thaw 2-cell mouse embryos.