선천성 풍진 증후군 1 예

정진호,이혜진,이선호,김성곤.Jin Ho Jeong. MD. PhD. Hye Jin Lee. MD. Sun Ho Lee. MD. Sung Gon Kim. MD 대한안과학회 2013 대한안과학회지 Vol.54 No.7

Purpose: We report a case of congenital rubella syndrome with bilateral zonular cataracts. Case summary: A 69-year-old man visited the hospital with visual disturbance in both eyes. His mother had been diagnosed with rubella during pregnancy, exhibiting typical fever and rashes. His visual acuity and hearing ability had been poor since birth. Corrected visual acuity was 0.3 in the right eye and 0.4 in the left eye. Slit lamp examination revealed bilateral zonular cataracts. On pure tone audiometry test, pure tone hearing threshold was 73 dB in the right ear and 72 dB in the left ear, corresponding to severe hearing loss in both ears. Echocardiogram showed a 1.5 cm-sized ostium secundum atrial septal defect, causing atrial fibrillation. Laboratory workup revealed an extremely high level of IgG antibody (titer = 1:301), and negative IgM antibody. A rubella IgG avidity test was 95.5%, suggesting remote rubella infection. Chromosomal analysis from peripheral blood did not show any abnormalities. The patient was diagnosed with congenital rubella syndrome with bilateral zonular cataracts. Two months after cataract surgery on both eyes, visual acuity steadily improved to 1.0 in both eyes. Conclusions: Congenital rubella syndrome is comprised of physical abnormalities such as sensorineural hearing loss, eye defects including congenital cataract, and cardiovascular defects due to gestational rubella infection. The possibility of congenital rubella syndrome should be considered even in old age, and a systemic multi-organ approach is necessary for therapeutic planning.

2.2 mm 및 2.8 mm 절개 백내장 수술에서 초음파 동역학이 술후 각막부종에 미치는 영향 비교

정진호,이혜진,이선호,Jin Ho Jeong,Hye Jin Lee,Sun Ho Lee 대한안과학회 2013 대한안과학회지 Vol.54 No.5

Purpose: To compare the effects of phacodynamic parameters on postoperative corneal edema between 2.8 mm and 2.2 mm microincisional coaxial cataract surgery. Methods: A prospective randomized study design was conducted and included 144 cases randomly divided into 2 coaxial cataract surgery groups based on incision size, a 2.8 mm incision (n = 72) or a 2.2 mm microincision (n = 72). The cataract was graded using the lens opacity classification system (LOCS III). The total ultrasound time (TUT), cumulative dispersed energy (CDE), average torsional amplitude (ATA), fluid amount, and case time were measured for each surgery. Central corneal thickness (CCT) was measured preoperatively, and 1 day and 1 month postoperatively. Intraoperative parameters were correlated with postoperative corneal edema. Results: The average nuclear opacity, intraoperative parameters, and postoperative corneal edema did not differ significantly between the 2 surgical groups. Regression analysis showed corneal edema to be significant in ATA (p = 0.028) in the standard (2.8-mm incision) coaxial group, whereas edema was significantly different with TUT (p = 0.001), CDE (p = 0.001), fluid amount (p = 0.021), and case time (p = 0.027) in the microcoaxial (2.2-mm microincision) group. CCT returned to baseline with an increase of 1.8% at 1 month. Conclusions: In the microcoaxial group, sustained ultrasound exposure and prolonged case time caused moderate postoperative corneal edema, while ATA was a significant factor in the standard coaxial group. These data can be used to devise an effective surgical strategy for cataract treatment.

Hoffer Q와 SRK/T 인공수정체 도수 계산 공식의 이론적 임상적 비교

정진호,김성곤,이혜진,이선호,차동민,Jin Ho Jeong,Sung Gon Kim,Hye Jin Lee,Sun Ho Lee,Dong Min Cha 대한안과학회 2014 대한안과학회지 Vol.55 No.1

Purpose: To evaluate the biometric conditions causing increased disparity in the calculation of intraocular lens (IOL) power between the Hoffer Q and SRK/T formulas. Methods: A prospective comparative study was conducted on 365 uneventful, cataract surgeries performed at a tertiary care center by one surgeon. The IOL power was calculated using both the Hoffer Q and SRK/T formulas with A-scan biometry. For a selected IOL power, the expected disparity between the 2 formulas (EDF) was measured and the EDF value was used to categorize the cases. The resultant error associated with each formula was determined at postoperative 6 weeks. KAL was defined as the product of mean corneal power (K) and axial length (AL). Postoperative errors of both formulas were calculated and their association with preoperative biometry measurements analyzed. Results: In 17.8% of the cases, the EDF was larger than 0.4 D, possibly leading to different IOL diopter recommendations. The EDF value and the product of corneal curvature and axial length were significantly correlated (R2 = 0.855, p < 0.001). Multiple regression analysis of causative preoperative biometric factors on the postoperative formula errors showed that astigmatism, anterior chamber depth (ACD), and lens thickness (LT) were significantly associated with Hoffer Q error and SRK/T error. Conclusions: Overall, both formulas performed very well when recommending the correct IOL power. The cause of disparity between the predicted refraction for the 2 formulas was more associated with KAL than K or AL alone. Astigmatism, ACD, and LT were the causative factors for the postoperative errors in both formulas. J Korean Ophthalmol Soc 2014;55(1):85-92

긴 앞쪽 수정체 소대 및 색소 분산 증후군 1예

정진호,김성곤,이혜진,이선호,차동민,Jin Ho Jeong,Sung Gon Kim,Hye Jin Lee,Sun Ho Lee,Dong Min Cha 대한안과학회 2014 대한안과학회지 Vol.55 No.1

Purpose: To report a case of long anterior lens zonule and pigment dispersion syndrome. Case summary: A 67-year-old female visited our clinic with complaint of visual disturbance in the left eye. She had no history of nyctalopia. Visual acuity was 0.6 in the right eye and 0.4 in the left eye. Intraocular pressure was 12 mm Hg in the right eye and 16 mm Hg in the left eye. Nuclear sclerosis was observed in the left lens. There was no pseudoexfoliative material observed. In the left eye, long anterior zonules with brown pigmented lens striae were spotted irregularly in every direction of the anterior lens. On gonioscopy, the angle was open, and dense, uniform, trabecular meshwork pigmentations were observed at the interior 120 degrees. On fundus examination, cup-to-disc ratio was 0.4 in the right eye, 0.3 in the left eye, and multiple hard exudates were observed in both retinas. Axial length was 22.03 mm in the right eye and 21.84 in the left eye. Anterior chamber depth was 2.71 mm in the right eye and 2.47 mm in the left eye. Defects in the retinal nerve fiber or visual field examination were not observed and pigment dispersion syndrome was diagnosed. The patient showed no significant change at the 9-month follow-up. Conclusions: We diagnosed atypical pigment dispersion syndrome associated with long anterior zonules and pigmented lens striae. Late onset retinal degeneration should be ruled out with chromosomal analysis if patients show nyctalopia, retinal pigment epithelium atrophy, or family history. J Korean Ophthalmol Soc 2014;55(1):133-137

봄철 산행 전 꼭 알아두어야 할 스트레칭

정진호,Jeong, Jin-Ho 한국건강관리협회 2008 건강소식 Vol.32 No.5

봄의 기운이 완연하고 황사마저 잠시 주춤하면 건강을 위해 운동을 시작하려는 사람이 많아진다. 특히 4-5월에는 여기저기에서 걷기대회, 마라톤대회 등 각종 운동관련 대회가 많이 열리고, 가족이나 직원들끼리 산행을 계획하기도 한다. 그런데 평상시 체력관리를 하지 않고 주변에서 각종 대회에 참가한다고 아무런 준비 없이 따라 출전하여 심각한 부상을 입고, 고생하는 이들이 많다.

레이져 레이 트레이싱 방식 수차계와 쉑-하트만 방식 수차계의 임상 비교

정진호,김명준,차흥원,Jin Ho Jeong,Myoung Joon Kim,Hung Won Tchah 대한안과학회 2006 대한안과학회지 Vol.47 No.12

Purpose: To compare ocular aberrations measured with a laser ray tracing aberrometer (iTrace?, Tracey technology) or a Shack-Hartmann aberrometer (ZywaveTM, Bausch & Lomb). Methods: A total of 68 eyes were included in this study. After manifest refraction (MR) and pupil dilation, aberrations and phoroptor predicted refraction (PPR) were measured with the ZywaveTM and iTrace? devices. The study group was subdivided into a more myopic group (<-4.33 Diopter (D)) and a less myopic group (>-4.33 D). The root mean square (RMS) errors of the total high order, spherical, coma and 3rd~5th order aberrations were compared. Results: The mean and SE of MR was -4.33±2.03 diopter (D), and that of the PPR was -4.20±2.13 D in iTrace? and -4.42±2.23 D in ZywaveTM. A paired-t test of the PPR and MR indicated that they were not statistically different. Zernike coefficients were expressed in the opposite sign in the 2nd and 4th order. The coma and spherical aberrations were larger in ZywaveTM. In a scattergram of each Zernike coefficient, the coefficient of determination (R2) was very low with higher order aberrations, with an exception for coma and spherical aberrations. The correlation of RMS error was greater in the less myopic group. Conclusions: Taking PPR values as a good reference of MR was a reliable method. For the HOA, only coma and spherical aberrations showed good correlations between ZywaveTM and iTrace?, and the correlations for HOA were decreased for the high myopic eyes.

가열용융 방법에 의한 Ge-BPSG 마이크로렌즈 어레이 제작

정진호,오진경,최준석,최기선,이형종,배병성,Jeong, Jin-ho,Oh, Jin-Gyeong,Choi, Jun-Seok,Choi, Gi-Seon,Lee, Hyeong-Jong,Bae, Byeong-Seong 한국광학회 2005 한국광학회지 Vol.16 No.4

화염가수분해 증착법(FHD : Flame Hydrolysis Deposition)으로 제작된 Ge이 첨가된 BPSG(Boro-Phospho-Silicate-Glass)막의 표면을 절단톱(dicing saw)을 이용하여 일정한 깊이로 절단함으로써 각 단위 마이크로렌즈 셀들을 형성시켰다. 또한 절단된 각 단위 마이크로렌즈 셀들을 가열용융(thermal reflow) 방법을 이용하여 $1200^{\circ}C$에서 가열용응시킴으로써 직경이 $53.4{\mu}m$인 마이크로렌즈 어레이를 제작할수 있었다. 이 때 렌즈간 간격은 $70{\mu}m,$ 렌즈 두께는 약 $28.4{\mu}m$이었다. 제작된 마이크로렌즈 어레이의 형상을 이미지-프로세스로 분석하였으며. 초점거리는 $62.2{\mu}m$이었다. 본 제작방법은 일반적인 사진식각 공정을 이용한 마이크로렌즈 제작보다 간단하면서도 저렴한 비용으로 제작이 가능하다. 또한 곡률반경의 조절이 용이하고, 보다 정밀하며 다양한 마이크로렌즈 어레이를 구현할 수 있다. Microlens cells of Ge-doped BPSG (Boro-Phospho-Silicate Glass) are fabricated by dicing the film produced by FHD (Flame Hydrolysis Deposition). Microlens arrays of $53.4{\mu}m$ square unit are produced by the thermal reflow of the diced unit cells at $1200^{\circ}C$. The gap between the microlenses was about $70{\mu}m,$ and the thickness of the produced lens was about $28.4{\mu}m$. We analyzed the reflowed shape of the microlens cell by an image-process technique, and the focal length was about $62.2{\mu}m$. This method of fabricating a microlens is simple and inexpensive compared to the conventional method using the photolithographic process. Also, the control of the radius of curvature of the microlens is easier and a more precise microlens way of various types can be fabricated using this method.

봄을 맞이하는 기지개 같은 스트레칭

정진호,Jeong, Jin-Ho 한국건강관리협회 2008 건강소식 Vol.32 No.3

황사를 피해 실내에서 가볍게 할 수 있는 스트레칭

정진호,Jeong, Jin-Ho 한국건강관리협회 2008 건강소식 Vol.32 No.4

"초정밀 조립기술 및 평가기술 확보통해 광학선진국 진입 앞당겨야"

정진호,Jeong, Jin-Ho 한국광학기기산업협회 2006 光學世界 Vol.106 No.-

국내 광학산업에서 필자가 아쉬워하는 분야는 초정밀 조립분야이다. 아무리 부품을 잘 만들어도 초정밀 조립을 통하지 않으면 총정밀 시스템이 완성되지 않는다. 이러한 시스템의 가격은 몇 억, 몇 십억, 몇 백억, 심지어 위성카메라와 같은 광학시스템은 몇 천억원을 호가한다. 불과 몇 백원,몇 천원,몇 만원짜리 렌즈를 대량생산하며 대한민국 광산업 기술을 논하는 시대는 가고 있다. 이제 수백만원, 수천만원을 논하는 광학계로 눈을 돌려야 한다.