소아 연령에서 발견된 medullary sponge kidney

정우영,조민현,구영란,임선희,정해일,Chung, Woo Yeong,Cho, Min Hyun,Gu, Young-Ran,Leem, Sun-Hee,Cheong, Hae Il 대한소아신장학회 2012 Childhood kidney diseases Vol.16 No.2

Medullary sponge kidney disease (MSK)는 신장 수질 피라미드부위에서 야기되는 희귀질환으로 collecting precalyceal duct의 낭종성 확장(dilatation)과 ectasia을 특징으로 한다. MSK 환자의 발생 빈도에 대해서는 명확히 알려진 바가 없으며, 특히 소아 청소년 연령에서는 매우 드물게 발견된다. 연구자들은 국내 소아신장학회 회원들을 대상으로 MSK 환자의 전수 조사를 실시하였고 현재까지 문헌상으로 보고된 관련 유전자들인 GDNF, ATP6V1B1, ATP6V0A4 유전자에 대한 분석을 실시하였기에 이를 보고하는 바이다. Purpose: Medullary sponge kidney (MSK) is a rare congenital disease characterized by diffuse ectasia or dilatation of precalyceal collecting tubules. MSK incidence and prevalence in the general population is uncertain and only a few patients are reported especially in the pediatric age. There has been increasing reports of patients with MSK who have other malformative disorders. Also several case reports concerning about etiological association of some genes. Methods: Collaborative study through nation-wide survey was done to investigate the incidence and etiological association of some genes such as GDNF gene, ATP6V1B1, ATP6V0A4 gene in developing MSK in Korean children. Results: Four cases of MSK who have various other malformative disorders were collected. There are no mutations of GDNF gene, ATP6V1B1, ATP6V0A4 gene in all patients. Conclusion: MSK is one of the very rare diseases in pediatric age. The etiological association of GDNF gene, ATP6V1B1, ATP6V0A4 gene in developing MSK in Korean children is not proved.

사구체신염에서 MIB-1을 이용한 Ki-67 항원의 발현

정우영,송민섭,김영주,Chung, Woo-Yeong,Song, Min-Seop,Kim, Young-Ju 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.2

목 적 : 증식성 핵 항원인 Ki-67의 발현은 조직 표본에서 세포증식의 활성도를 나타내어 주는 매우 유용한 표식자로 이용되고 있다. MIB-1은 포르말린에 고정되고 파라핀 포매된 조직에서 Ki-67항원을 인식해 낼 수 있는데, 단클론성 항체 MIB-1을 이용하여 각종 사구체신염에서 사구체 및 신세뇨관의 MIB-1발현 정도를 알아보고, 특히 메산지움의 증식을 가지는 사구체신염의 진단에 도움이 될 수 있는지를 조사하기 위하여 본 연구를 실시하였다. 대상 및 방법 : 1994년 1월부터 1996년 12월 사이에 인제의대 부산백병원 소아과에 입원하여 신질환이 의심되어 신생검을 시행한 환자 중 사구체신염으로 진단된 15세 이하의 환자 41례를 대상으로 하였다. 면역조직화학적 염색은 Ki-67에 대한 MIB-1(Immunotech, 505)항체를 이용하였으며, 판정은 모든 사구체의 세포수에 대해서 세포의 핵에 적갈색의 과립이 보이는 세포수를 백분율로 구하여 MIB-1 표지지수로 난타내었다. 결과 : 1. 미세변화 신염과 막성 신염에서는 전례에서 사구체 및 신 세뇨관에서 MIB-1의 발현은 관찰되지 않았다. 2. IgA 신증의 경우에는 18례에서 단지 2례 ($11.1\%$)에서만 사구체의 메산지움 세포와 신 세뇨관 세포에서 MIB-1이 발현되었으며, 7례에서는 신 세뇨관 세포에서만 MIB-1이 발현되었다. 3. 막증식성 사구체신염에서는 4례중 2례에서 사구체내에 MIB-1이 발현되었다. 4. 연쇄상 구균 감염 후 사구체신염의 경우에서는 5례중 4례에서 사구체 와 신 세뇨관 세포에서 MIB-1항원이 발현되었다. 결 론 :각종 신질환에서 사구체내 MIB-1의 발현은 사구체 및 신 세뇨관 세포의 증식상태를 어느 정도 반영한다고 생각된다. 그러나 IgA 신증의 경우에서 나타난 바와 같이 메산지움 세포에서의 발현율은 낮아서, 메산지움의 증식을 보이는 사구체신염의 진단에 도움을 줄 수 있는 지표로서의 의미는 제한적인 것으로 사료된다. Purpose : The proliferative nuclear antigen Ki-67, present in all cell cycle phases except G0, is a useful marker for the detection of proliferative cells in vivo. MIB I has been found to recognize an antigen in formalin-fixed and wax-embedded material. The aim of this study was to assess the efficacy of MIB-1 expression as a marker of representing the status of mesangial cell proliferation in renal tissues. Methods : Immunohistochemical staining for Ki-67 Ag using monoclonal antibody MIB-1 (Immunotech,505) were performed in 41 renal tissuses which were obtained by percutaneous renal biopsy done between January 1994 and December 1996. Results : In both glomeruli and renal tubules, MIB-1 expression was observed only in 2 of 18 ($11.1\%$) cases of IgA nephropathy, in 2 of the 4 ($50\%$) cases of mebranoproliferative glomerulonephritis, in 4 of the 5 ($80\%$) cases of poststreptococcal glomerulonephritis. But MIB-1 expression was not detected in all cases of minimal lesion and membranous nephropathy. Renal tubules In another 7 cases of IgA nephropathy were MIB-1 positive. Conclusion : MIB-1 expression in renal tissues may relate to the cell proliferation in glomeruli and renal tubules. But the efficacy of MIB-1 expression as a marker of mesangial cell proliferation may reveal a limited value because of it's lower positive rate in IgA nephropathy.

중,고등학교 운동선수들의 스트레스 요인과 대처방안 인과모형 검증

정우영(Woo Young Chung) 한국사회체육학회 2013 한국사회체육학회지 Vol.0 No.53

The purpose of this study was to analyze the effect on stress factors and coping of student athletes. The data was collected from 390 student(male: 282, female: 108) athletes in seoul, Gyeonggi-do. Sports Stress Source Questionnaire(SSSQ) and Korea Athlete Sport Coping Scale(KASCS) as the investigation tools were used for the data collection. The data, which was collected by using AMOS 20.0, was analysed with confirmatory factor analysis(CFA) and structural equation modelling(SEM). The results of study were as follows. First, Major stress factor consisted of fear of failure, competition demands, senior-junior conflicts, and worry of injury. Major coping factor consisted of problem focused, emotional focused, avoidance. Second, social stress factor(senior-junior conflicts) had direct effect on 3 stress coping strategies(problem focused, emotional focused, avoidance). Mediating effect of 3 stress coping strategies was supported, and fitness of model was good.

스포츠교육 관찰행동분석연구에 있어서 컴퓨터 소프트프로그램의 활용

정우영(Woo-Young Chung) 한국코칭능력개발원 2006 코칭능력개발지 Vol.8 No.1

『初發心自警文諺解』 연구

정우영(Chung Woo Young) 동악어문학회 2008 동악어문학 Vol.51 No.-

이 연구는 『初發心自警文諺解』의 두 판본인 전라도 순천의 송광사판(1577)과 경기도 용인의 서봉사판(1583)을 대상으로 상호 대조ㆍ비교 검토하여 두 판본의 특징과 위상을 문헌학적 관점에서 밝히고, 두 판본에 나타난 언어의 차이를 국어사(방언사)의 관점에서 해석하여 1580년경의 전라도와 경기도 방언의 윤곽을 파악하려는 데 목적이 있다. 이를 위해 전체를 4장으로 구성하였다. 제2장에서는 두 판본에 나타난 大文의 分節, 구결문과 언해문의 체재, 번역 양상, 주석 등을 문헌학적 관점에서 검토하였다. 두 판본의 체재가 어디서 영향을 받았는지는 알 수 없으나, 대체로 16세기 초반 관판문헌의 체재와 유사하다. 송광사판의 구결문은 국한혼용체로 한자음 병기 방식이고 언해문은 순한글체이며, 서봉사판은 구결문 및 언해문 모두 국한혼용체로 한자음을 병기하였는데, 해당 지역의 독자층을 고려한 선택으로 해석된다. 번역에 있어서, 송광사판은 의역이 섞인 직역이고, 서봉사판은 송광사판보다 좀 더 엄격한 직역의 경향을 보인다. 서봉사판은 독립적으로 이루어진 것이 아니라 송광사판을 저본으로 하여 협주를 추가하고, 오류를 수정ㆍ보완하였으며 일부 구결을 바꿔 개역함으로써 통일성 있는 번역을 하였다. 제3장에서는 두 판본의 비교에서 드러나는 두 판본의 언어의 차이를 문자와 표기법, 음운ㆍ음운현상, 어휘의 측면에서 분석하여 국어사(방언사)의 관점에서 해석하였다. 15세기에 ‘ㅿ’으로 표기되던 단어가 송광사판에서 ‘ㅿㆍㅇㆍㅅ’로 다양하게 반영된 것은 전라도 방언의 특수성과 중앙어형 표기의 중압감에 영향을 받은 결과로 해석하였다. 두 판본의 한자음과 고유어 표기에 대한 분석 결과, 1580년대 초기까지 경기도 용인 지역은 구개음화가 일어나지 않았으나, 1570년 대 후반 전라도 순천 지역은 ‘ㄷ’ 구개음화가 상당히 진행된 것으로 추정된다. 또한 15세기에는 필수규칙이었던 ‘ㄱ’ 약화현상이 1580년경에는 전라도 방언과 경기도 방언에서 극히 축소되었으며, 오히려 ‘j’계 하향이중모음 또는 ‘ㄹ’ 아래에서 ‘ㅇ→ㄱ’과 같은 복구현상이 폭넓게 확산되어 가고 있음을 확인하였다. 송광사판의 어휘를 현대 전라남도 방언과 비교한 결과, 다음과 같은 어휘가 여전히 사용되고 있음을 확인하였다. 골[州], 그림재[影], 니서[連], 무뤂[膝], ?조[자주], ??거리고곰[학질] 등. 송광사판은 전라도 방언을 반영하고, 서봉사판은 경기도와 중앙어를 반영한 문헌으로, 16세기 후반기 전라도-경기도의 방언사를 재구하는 데 가치가 높은 자료들이다. 중세한국어 방언사 재구를 위해 지방에서 간행된 한글문헌 자료의 지속적인 자료분석과 검토가 요구된다. The paper investigates the Songgwang Temple edition (1577) and the Seobong Temple edition (1583) of Chobalsimjagyeongmun-eonhae(初發心自警文諺解) and elucidates their characteristics and importance in philological aspects. It sheds lights on the better understanding of the Gyeonggi and Jeolla dialects of around 1580 by comparing their manifestations in the two editions of the text in view of historical dialectology. The paper consists of 4 chapters. The chapter 2 provides a philological study of paragraph segmentation, the construction of Gugyeol and eonhae sentences, the aspects of translation and annotation, etc. The chapter 3 offers a historicodialectological analysis of the differences between the two editions of the text with regard to the alphabets used, orthography principles, phonetic and phonological phenomena, and lexical uses. The study of Sino-Korean pronunciations and the native language orthography in the two editions reveals that palatalization did not occur to the Gyeonggi dialect until around 1580, while /ㄷ/-palatalization was widely applied in the Jeolla dialect in the late 1570s. It is also revealed that /ㄱ/-weakening lost its force, while the falling diphthongs of /-j/ series and the reconstruction of /o/ to /ㄱ/ after /ㄹ/ were widely applied in both dialects of that time. The comparison between the words in the Songgwang Temple edition of the text and those in modern Jeolla dialect shows that the following words were used at that time: 골[州], 그림재[影], 니서[連], 무뤂[膝], ?조[자주], ??거리고곰[학질], etc. The words in the Seobong Temple edition corresponding to those in the Seobong Temple edition are 고올, 그림매, 니어, 무롶, ?로, ??머리고곰, etc, respectively. It is noteworthy that the latter have similar forms to those in the texts published in Hanyang in late 16C. Still, more works are in need to reconstruct dialects in the middle Korean period by examining carefully the then literature published in Korean.

Laser Surface Texturing을 이용한 STD61강에 대한 마찰특성에 관한 연구

정우영(Woo Young Chung),민준원(Joon Won Min),김상호(Sang Ho Kim),한형욱(Hyung Wook Han),이명호(Meung Ho Rhce),송종호(Jong Ho Song),정원용(Won Young Jeung) 한국트라이볼로지학회 2008 한국트라이볼로지학회 학술대회 Vol.2008 No.11

Laser texturing technology produces shallow dimples that serve as reservoirs for fluid media and trap the wear debris on material faces, so increase the lubrication efficiency of the materials. STD6l steel specimen has been fabricated by using laser texturing method to investigate friction characteristics through gap, depth and diameter. Marking laser system for laser texture showed reasonable results to modify dimple depth and size of steel. On specific lubricant condition. laser textured materials kept longer low friction characteristic than non treated material. After laser texturing, polishing process is positively necessary to remove the spatters attached on the surface. When used on well-controlled dimple surface. the test process results in substantial reductions in friction.

『訓民正音』언해본의 성립과 원본 재구

정우영(Chung Woo-Young) 국어국문학회 2005 국어국문학 Vol.- No.139

This paper is to find out the publishing periods of the Korean version of Hunminjeongeum (訓民正音 諺解本) in the beginning parts of Worinseokbo (月印釋譜), Volumes 1 and 2 published in 1459 (currently kept in Loyola Library at Sogang University) and reconstruct its original texts published in each period.<br/> Chapter 2 performed the textual analysis of the Korean transcription system and the handwriting system and examined Sejong Sillok (the Chronicles of King Sejong : 世宗實錄). It is found that the Korean version of Hunminjeongeum underwent three stages of changes: (i) translation, (ii) addition and (iii) revision of its original texts, thereby establishing itself to the present text.<br/> It is supposed that by translating the main parts of the Chinese version of Hunminjeongeum (訓民正音 漢文本) into Korean, the first version of the Korean version of Hunminjeongeum was published in book form during the period from September to the end of December in 1446, but not later than April 1447.<br/> By translating the system of transcribing the Chinese dental sounds and adding it to the first volume, the second version of Hunminjeongeum was published as a part that precedes Seokbosangjeol (釋譜詳節), Volume 1 in July 1447, the same time when Seokbosangjeolseo (the Preface of Seokbosangjeol : 釋譜詳節序) was, it is supposed.<br/> The third version of Hunminjeongeum is a prefacing volume in Worinseokbo published in 1459, that has been passed down on to us. By appending to the head title〈世?솅宗종御?엉製?졩〉after the death of King Sejong and by adding annotations to the second version, the third version had the lines 1-4 of page 1 established in present form.<br/> Chapter 3 reconstructed the original texts of Hunminjeongeum on the basis of the previous researches into the 15th century Korean and what we found in Chapter 2. Section 3.1 reconstructed the beginning parts of Worinseokbo, Volume 1, which have been handed down in damaged form. Section 3.2 reconstructed the prefacing volume of Seokbosangjeol. Finally, Section 3.3 reconstructed the first Korean version of Hunminjeongeum. The reconstructed material is reduced and presented in photograph.

유아체육에 대한 학부모의 인식도 차이분석

정우영(Chung Woo-Young),이재형(Lee Jae-Hyoung) 한국체육과학회 2005 한국체육과학회지 Vol.14 No.2

The purpose of this study is to research and analyze parents' perception on the effect of children's physical sducation on children's congnitive, emotional, and socal deveopment. It sought to provide basic data for more active children's physical education in children's educational environment. Data and the study results for this study were obtin through survey on 629 parent's with 5-7 years old children. the surveys were crried out on 12 private kindergartens, registered at Nlambeth borough council of Seoul, Which conduct children's physical education programs. For data analysis, statistical methods, Manova were used, operated on SPSS Window verson 11.0 program, the result of this study is as followed. different parents' perception were confirmed for children's gender, years and parent's career, a monthly income, whereas no discrepancy was found for parent's gender and years.

체육교사의 가치지향성에 따른 수업행동과 학생의 내적동기분석

정우영 ( Woo Young Chung ) 한국스포츠심리학회 2006 한국스포츠심리학회지 Vol.17 No.2

재활승마가 발달장애아동의 내적동기와 부모의 양육 스트레스에 미치는 영향

정우영(Chung, Woo-Young) 한국사회체육학회 2016 한국사회체육학회지 Vol.0 No.64

The purpose of this study was to examine the change of intrincs imotivation of disabled children of hippotherapy participations and parenting stress of parents. This sutdy will offer basic research materials of strategy of intrinsic motivation improvement of disabled children of hipotherapy participations and parenting stress management of parents. The sample of this study were 15 disabdle children and their parents. Forth is analysis, paired sample t-test was used by SPSS window 17.0 program on the quantitative analysis. Area analysis technique and classification system were used by records of training and in-depth interviews on the qualitative analysis. The finding soft his study were as follows; First, 8 weeks hippotherapy participations had positive influence on interest-enjoyment, tension-pressure and effort-importance among intrinsic motivation of disabled children. However, 8weeks-87-hippotherapy participations had not significantly influence on perceived competence among intrinsic motivation. For the quality data analysis, 8weeks hippotherapy participations had positive influence on interest-enjoyment(never lose their sense of smile, laughing faces and having to sings )t,ension-pressure (relieve anxiety and a fear of animals) and effort-importance (actively participate and challenge themselves) among intrinsic motivation of disabled children. Moreover, perceived competence had not significantly influence on the quantitative analysis also had positive changes on the qualitative analysis. Second 8, weeks hippotherapy participations had positive influence on a parent field and a child field among parenting stress of parents. For the quality data analysis, parents’ emotion variation, enjoying culture life and having hopes for the future disabled children, had positive influence on ade crease in parenting stress of parent