양방치료를 받고 있는 신경계질환아동에서 한방치료 및 기타 병행치료 이용실태에 관한 조사

정민정,임정화,황보민,김기봉,윤영주,Jeong, Min-Jeong,Lim, Jung-Hwa,HwangBo, Min,Kim, Ki-Bong,Yun, Young-Ju 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.2

Objectives The purpose of this study is to investigate prevalence and the frequency of using Korean medicine, Complementary Alternative Medicine (CAM), and other parallel treatments in children and young adolescence with neurological diseases. Methods From April to July 2011, parents of the children and adolescents patients suffering from neurological disease completed questionnaires. Results 578 parents answered the questionnaires. 310 cases (53.5%) were using Parallel Treatments. Types of the Parallel Treatments being used are as follows. Rehabilitation 166 cases (27.4%), Speech Therapy 169 cases (27.9%), Education (Art, Music, Play) 109 cases (18.0%), Health supplement 72 cases (11.9%), Counselling, Cognitive & Behavioral Therapy 45 cases (7.4%), Herbal Medicine 24 cases (4.0%), Acupuncture, Moxibustion 13 cases (2.1%), Neurofeedback Therapy 1 case (0.2%), Etc 7 cases (1.2%). 257 cases (44.5%) have used Parallel Treatment before. Parallel Treatments being used in the past are as follows. Herbal Medicine 146 cases (35.4%), Acupuncture, Moxibustion 64 cases (15.5%), Education (Art, Music, Play) 54 cases (13.1%), Rehabilitation 47 cases (11.4%), Speech Therapy 46 cases (11.1%), Health supplement 30 cases (7.3%), Counselling? Cognitive & Behavioral Therapy 15 cases (3.6%), Neurofeedback Therapy 4 case (1.0%), Chuna, Manual Massage 2 case (0.5%), Etc 5 cases (1.2%). Conclusions Although patients were on both western medicine and Korean medicine, CAM, and other parallel treatment, the ratio of Korean medicine treatment was not as high as expected. Further studies are required to develop the model of integrative medicine.

Anti-inflammatory Activities of GyejigaChulBuTang on Lipopolysaccharide-stimulated RAW264.7 Cells

정민정,이승연,유선애,강경화,Jeong, Min-Jeong,Lee, Seung-Yeon,Yu, Sun-Ae,Kang, Kyung-Hwa The Association of Korean Oriental Pediatrics 2014 대한한방소아과학회지 Vol.28 No.3

Objectives GyejigaChulBuTang (GCBT) is a prescription used to treat acute and chronic arthritis in Korea, China, and Japan. This study assessed the anti-inflammatory and anti-oxidant activities of GCBT on lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Methods Raw264.7 cells were pretreated with or without GCBT for 1 hour prior to incubation with LPS. Anti-inflammatory activity of GCBT was evaluated with reference to gene expression and production levels of proinflammatory cytokines ($TNF{\alpha}$, IL-$1{\beta}$, IL-6, GM-CSF and $INF{\gamma}$) and inflammatory mediators (iNOS, COX-2, NO and $PGE_2$). In addition, intracellular ROS generation and signal transduction of MAPK family, PI3K/Akt and $I{\kappa}B{\alpha}/NF{\kappa}B$ was investigated. Results Prior treatment with GCBT inhibited elevation of $TNF{\alpha}$, IL-$1{\beta}$, IL-6, GM-CSF, $INF{\gamma}$, NO and $PGE_2$, together with their cognate mRNAs in a dose-dependent manner. Intracellular ROS contents were similarly reduced. These effects were due to inhibition of LPS-induced phosphorylation of MAPK family, PI3K/Akt and $I{\kappa}B{\alpha}$ as well as nuclear translocation of $NF{\kappa}B$. Conclusions GCBT suppresses pro-inflammatory mediators. GCBT has potential in the treatment of juvenile rheumatoid arthritis associated with inflammation.

오령산의 고혈압 치료약물 가능성에 대한 개관

정민정,강기완,강자연,윤지현,최유민,김홍준,선승호,장인수,Jeong, Min-jeong,Kang, Ki-wan,Kang, Ja-yeon,Yoon, Jee-hyun,Choi, Yoo-min,Kim, Hong-jun,Sun, Seung-ho,Jang, In-soo 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent. Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed. Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects. Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.

한약 투여가 사춘기 전 소아의 신장성장에 미치는 영향에 대한 예비 연구

정민정,곡수영,이승연,Jeong, Min-Jeong,Gok, Su-Yeong,Lee, Seung-Yeon 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.3

Objectives : The aim of this study was to evaluate the effect to the height-growth after the administration of herbal medicine to the prepuberty children Methods : This clinical study has been carried out with 18 children, who visited to the Department of Pediatrics, Dong-eui oriental medical center from January 2005 to August 2008. They had been treated for height-growth with herbal medicine more than 6 months. This study has been carried out by chart-review to see the effectiveness. Height percentile, BMI and GV(Growth Velocity) after medication was compared with the ones before medication. Results : 1. This clinical study has been carried out with 18 children, 12 boys(66.7%) and six girls(23.3%). Their average age was 10.30 years old. 2. Generally total children's average height percentile was increased compared to after medication. Especially eight of them has significantly increasd height percentile(44.4%). 3. Total children's average GV/6months was also increased after medication. Especially ten of them has significantly increasd GV/6months (55.6%). 4. Total children's average BMI also increased (17.01 to 17.85) after medication. Conclusions : Herbal medicine affects to the growth of pre-puberty children.

소아 전문 한의사를 대상으로 실시한 하태독법의 인식 및 사용실태 조사

정민정,Jeong, Min Jeong 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.2

Objectives This study is to know the current usage of Ha-Taedok Method in Korean pediatrician. Methods 69 questionnaires were statistically analyzed by using PASW Statistics 18. Results 55 Korean Medicine doctors knew Ha-Taedok Method, but only 2 doctors were using Ha-Taedok Method in their practice. The doctors tend not to use Ha-Taedok Method because it was hard to get permission from the patient's caregiver. 11 Korean Medicine doctors used Ha-Taedok Method to their own children though. The pediatricians felt satisfied from the effect of Ha-Taedok Method especially because it can prevent from disease. They reported no side effect and adverse effect. Coptidis Rhizoma is a preferred herb to use along with Ha-Taedok Method. For a better result from Ha-Taedok Method, it is recommended to start within 3 days old of patient. Conclusions Ha-Taedok Method may be effective as preventive method.

소아복통 환아에 대한 향사육군자탕 가미방의 임상적 효능에 관한 연구

정민정,유선애,이승연,Jeong, Min-Jeong,Lyu, Sun-Ae,Lee, Seung-Yeon 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.3

Objectives This study for evaluating the effects of HyangsayukgunjatangGamibang on childhood with abdominal pain. Methods This clinical study has been carried out with 38 children, who visited to the Department of Pediatrics, $\bigcirc\;\bigcirc$oriental medical center from January 2005 to August 2007, who had been treated for abdominal pain with herbal medicine (HyangsayukgunjatangGamibang). This study had done by chart-review or by telephone research. Results 1. After treating with HyangsayukgunjatangGamibang, 34 children's abdominal pain was improved. (63.2%) 2. After treating with HyangsayukgunjatangGamibang, 13 children eat more than before. 3. After treatment with HyangsayukgunjatangGamibang, children's symptoms-constipation, nausea, headache, anorexia were improved. Conclusions HyangsayukgunjatangGamibang is effective in childhood abdominal pain.

우리나라 학동전기 아동에서 비만진단을 위한 체지방률 백분위수

정민정,윤영주,김봉현,김기봉,Jeong, Min-Jeong,Yun, Young-Ju,Kim, Bong-Hyun,Kim, Ki-Bong 대한한방소아과학회 2011 대한한방소아과학회지 Vol.25 No.1

Objectives: This study was designed to regulate the percentile of body fat percentage by Bioelectrical Impedence Analysis (BIA) in order to detect overweight and obesity in preschool children. Methods 1301 three to six year old children's height, weight, and body fat percentage using BIA was measured. Results: The percent of the boys with 85th percentiles of the body fat percentage were 22.3%(3years), 23.4%(3.5years), 23.9%(4years), 24.8%(4.5years), 22.8%(5years), 24.6%(5.5years) and 23.8%(6years). The percent of the girls with 95th percentiles of the body fat percentage were 24.9%(3years), 27.5%(3.5years), 27.3%(4years), 28.6%(4.5years), 28.1%(5years), 33.3%(5.5years) and 32.7%(6years). For the girls, the percent of girls with 85th percentiles of body fat percentage were 23.3%(3years), 24.4%(3.5years), 23.6%(4years), 23.7%(4.5years), 24.7%(5years), 26.0%(5.5years) and 28.1%(6years). And the 95th percentiles of the body fat percentage were 28.6%(3years), 27.3%(3.5years), 25.4%(4years), 28.0%(4.5years), 31.7%(5years), 33.5%(5.5years) and 36.4%(6years). Conclusions: The 85th percentiles of body fat percentage to classify as overweight and the 95th percentiles of body fat percentage to classify as obesity were accord with the Body Mass Index (BMI) criteria by the Korean pediatrics society in 2007.

주의력부족 과잉행동장애 환아에 대한 임상현황연구

정민정,이승연,Jeong, Min-Jeong,Lee, Seung-Yeon 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.3

Objectives: The purpose of this study is to investigate the present situation for oriental examination and treatment of ADHD by questionnaire. Methods : We surveied oriental clinics which publicized on internet that they run a clinic of ADHD and oriental university hospitals which had a department of Pediatrics or Neurophycholosy. Results : The number of responding that the period of actively attending upon treatment of ADHD children was less than 3 years was 9(60%). The number of responding that in these 3 months, the number of ADHD children visiting clinics were under ten was 8(53.3%). The number of responding that the average age of ADHD children visiting clinics were 7 to 10 years old were 10(66.7%). The number of responding that they assessed diagnosis of ADHD children were 7(46.7%). The number of responding that they assessed oriental medical examination to ADHD children were 9(60%). The number of responding that the most effective treatment to ADHD children was Herbal Medicine was 10(66.7%). The number of responding that the interval of treatment of ADHD was 1 to 3 months was 9(60%). Conclusions : Recently oriental medical treatments for ADHD has been attempted. Treatment methods were herbal medicine, acupuncture, parents education, etc. But further studies are needed.

한방산후조리원 산모를 대상으로 실시한 하태독법의 인식 및 의향 조사

정민정,Jeong, Min Jeong 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.4

Objectives Purpose of this study is to investigate the current usage of Ha-Taedok Method in postpartum women. Methods 36 questionnaires were statistically analyzed by using PASW Statistics 18. Results Only 2 women knew Ha-Taedok Method (5.6%). Women tend not to use Ha-Taedok Method because their children were too young to take herbal medicine (27.8%). However, when being educated about Ha-Taedok Method, they were more likely to take this method than before (13.2%${\rightarrow}$75%). Conclusions The utilization of Ha-Taedok Method will improve up on educating post-partum women.

우리나라 양산지역 학동전기 아동에서 비만 진단을 위한 체지방률의 절단값

정민정,김기봉,Jeong, Min-Jeong,Kim, Ki-Bong 대한한방소아과학회 2010 대한한방소아과학회지 Vol.24 No.2

Objectives The objectives of this study were to evaluate the correlations between the indices of obesity and percentage body fat by bioelectrical impedance analysis(BIA). Also, this study was designed to define the cut off values of percentage body fat by BIA which would represent BMI and degree of obesity in order to detect overweight and obesity in preschool children. Methods The height and weight of 683 children aged four to six years old were measured. Also, percentages of body fat were measured by BIA. Results There were high correlations between the boy's body fat percentages and degree of obesity(r=790). Also, there were high correlations between the girl's body fatpercentages and BMI(r=778). The cut off values of body fat percentage, which would correspond to those of BMI percentiles, were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.55% in boys and 22.35% in girls. For obesity, the cut off values were 28.80% in boys and 27.60% in girls. The cut off values of body fat percentage, which would correspond to degree of obesity were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.75% in boys and 22.35% in girls. For obesity, the cut off values were 29.05% in boys and 28.75% in girls. Conclusions According to the BMI criteria by the Korean pediatrics society in 2007, the most appropriate cut off values of body fat percentage in for four to six years old children were follows; for boys, 19.55% considered as overweight, and 28.80% as obese while for girls, 22.35% considered as overweight and 27.60% as obese. According to suggested degree of obesity criteria, the most appropriate cut off values of body fat percentage in for four to six old children were were follows; For boys, 19.75% was considered as overweight, and 29.05% as obesity. For girls, 22.35% was considered as overweight, and 28.75% as obese.