화폐상 습진에 병발한 급성 알레르기성 피부염 한방 치험 1례

장인욱,장정현,윤화정,고우신,Jang, In-Wook,Jang, Joung-Hyeon,Yoon, Hwa-Jung,Ko, Wo-Shin 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.4

Objective : The purpose of this report is to know the effect of oriental medical treatments on acute allergic contact dermatitis with multiple nummular eczema. Methods : We treated a 34-years-old woman patient with acute allergic contact dermatitis on face and multiple nummular eczema on both arm, right ankle and left inguinal region by Korean medicine. After Korean medical treatment for 42 days in hospital, we measured the decrease of exudation and pruritis as well as recovery of skin damages. We recorded pictures of changes on symptoms. Results & Conclusion : The symptoms of ACD and nummular eczema were significantly improved except scars. Exudation and pruritis were disappeared and skin damages were almost recovered until discharge from hospital. After 20 days we could confirm the symptoms were clearly disappeared. Thus Korean medical treatments are effective on ACD and nummular eczema.

당뇨 쥐에 대한 한약재복합추출물로 만든 현미율무밥의 혈당강하 효과

이현순 ( Hyeon Sun Lee ),공현주 ( Hyun Joo Kong ),이언희 ( Eon Hee Lee ),황수정 ( Su Jung Hwang ),정현아 ( Hyeon A Jung ),김미림 ( Mi Lim Kim ),최은미 ( Eun Mi Choi ),장정현 ( Joung Hyeon Jang ),양경미 ( Kyung Mi Yang ) 대한본초학회 2014 大韓本草學會誌 Vol.29 No.3

Objectives : The purpose of this study was to evaluate boiled rice made from unpolished rice, Job`s Tears, and extract from medicinal herbs mixture (HGMCJE) for hypoglycemic effect on STZ-induced diabetic rats. Methods : In the response of glucose tolerance, control and diabetic rats groups was intubated with glucose and HGMCJE. Furthermore, boiled 100% polished rice (P rice), boiled unpolished rice mixed with white rice and Job`s tears (polished rice:unpolished rice:Job`s tears=60:25:15, UPJ-rice), and UPJ rice made from HGMCJE (HUPJ-rice) were intubated to control and diabetic rats groups, respectively. Then, blood glucose concentration, incremental blood glucose, and area under the curve (ΔAUC) were analyzed in every experimental groups, and these data were used to evaluate glycemic response. Results : When glucose and p rice were intubated in control and diabetic rats, blood glucose concentration, incremental blood glucose, and incremental response ΔAUC of diabetic groups were significantly increase than control groups. But administraion of a single dose of extract from medicinal herbs mixture and HUPJ-rice in control and diabetic rats inhibited the remarkable increase the level of postprandial blood and ΔAUC at 60, 90, and 120 min Conclusions : These results indicate that when intubation of glucose and P rice were out of control on postprandial glycemic response in diabetic rats. But postprandial glycemic response was well-modulated by administrating a single oral dose of HGMCJE and HUPJ-rice. Therefore, HGMCJE can be developed as an effective hypoglycemic agent.

과체중 및 비만 여성들을 위한 한방 체중조절 프로그램의 교육 효과

양경미 ( Kyung Mi Yang ),장정현 ( Joung Hyeon Jang ) 한국미용학회 2007 한국미용학회지 Vol.13 No.2

This study was conducted in order to investigate the effects of weight control and changes in health-related factors on over weight and obese women. The subjects consisted of 68 women (BMI≥23) who participated in Herbal weight control educational program from Yeong Yang Health center in Gyeongsangbuk-do. Thirty women completed this program. The contents of the program for 10 weeks contained nutrition education, counseling, behavior modification and exercise. The items of surveyed was general characteristics and anthropometric measurement of the over weight and obese women, their eating behaviors, food habits, nutrition knowledge test, and its evaluation comparisons between the before and after the education. The eating behaviors, food habits, and nutrition knowledge were surveyed by using questionnaires. The data were analyzed using SPSS program. The results from this study were as follows. The subjects showed a significant reduction in weight, body fat mass, BMI(body mass index) and waist circumference after body weight control program. Weight, BMI and PIBW(percent ideal of body weight) were 69.6±12.9kg, 28.3±4.31 kg / m2 and 138.8±21.9% at the before education and fell to 67.3±12.0, 27.6±4.1kg / m2, 135.7±21.4% after education(p<0.001). Waist(p<0.001) and hip(p<0.05) circumference were 94.2±11.5 cm and 100.9±7.67cm at the before education and fell to 91.8± 10.9cm and 98.5±8.91cm after education After the education, all subjects` eating behaviors were significantly changed positively. Also the mean nutrition knowledge and food habits scores(p<0.05) were significantly improved after the education. These findings indicate that a well-designed program for Herbal weight control education can help to encourage food habits themselves and change nutrition knowledge. Also body weight, body mass index, weight-hip ratio and waist circumference of pre-education group and post-education were significantly decreased. The performance of an educational program is beneficial for over weight and obese women based on the health-related quality of life.

한방영양교육프로그램을 통한 과체중 및 비만여성에 대한 생화학적 연구

양경미 ( Kyung Mi Yang ),장정현 ( Joung Hyeon Jang ) 한국미용학회 2009 한국미용학회지 Vol.15 No.1

This study was performed to evaluate the effectiveness of nutritional education program conducted to overweight or obese women in public health center, Yeongyang-gun, Gyeonbuk, south korea. The subjects of this study consisted of 33 overweight or obese women(BMI≥23.0) in the age of 35-55 in Yeongyang-gun area, and the educational period was 8 weeks. Before or after carrying out the nutritional education to overweight or obese women, we analyzed the antheropometric parameters, biochemical indices, dietary behaviors, dietary habits and nutrition knowledge through chi-test and student`s t-test using SPSS. Weight, relative body weight(RBW), body mass index (BMI), body fat weight and body fat ratio of overweight or obese women were significantly decreased(p<0.05) after the nutritional education. Moreover, the levels of triglyceride, total cholesterol and LDL-cholesterol in serum were meaningfully decreased after the nutritional education. Furthermore, Their food habits and nutritional knowledge score were highly improved after the nutritional education. However, the nutritional education did not affect the ratio of abdominal fat, the activities of GOT and GTP and the level of albumin or globulin. There were no significant differences in AI((total cholesterol-HDL-cholesterol)/HDL-cholesterol), CRF(total cholesterol/HDL-cholesterol,LHR (LDL-cholesterol/HDL-cholesterol) and HTR(HDL-cholesterol/total cholesterol) between before and after the nutritional education program. In conclusion, the nutritional education program can be applied for the nursing intervention in the overweight or obese women.

홍화씨와 한약재 혼합추출물이 Streptozotocin으로 유도한 흰쥐의 혈당과 혈액 성분에 미치는 영향

양경미(Kyung-Mi Yang),신승렬(Seung-Ryeul Shin),장정현(Joung-Hyeon Jang) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.2

당뇨병은 생체내 당 이용 능력의 이상으로 일어나는 만성대사성 질환으로서 심혈관계 합병증이 일으키는 대표 증상인 고혈당과 지질대사를 치료하기 위하여 많은 환자들이 민간요법에 의존하고 있다. 이에 본 연구는 홍화씨와 한약재혼합 추출물이 혈당강하와 지질상태 개선에 대한 효능을 검증하고자 실시하였다. 당뇨는 streptozotocin(45 ㎎/㎏ B.W.)으로 S.D.계 흰쥐에게 근육주사로 유도시킨 다음 주재료로 볶은 홍화씨 50 g, 100 g 각각에 부재료로 맥문동, 감초, 상엽, 백복령, 숙지황, 비파엽, 독활, 대추, 산수유, 목단피, 천화분, 오미자를 섞어서 만든 한방 혼합 추출물을 당뇨 유도 쥐에게 체중 ㎏ 당 100 ㎎, 200 ㎎의 홍화씨를 섭취할 수 있도록 각각 경구 투여하였다. 당뇨쥐의 고혈당 증상은 100 g의 홍화씨를 넣고 추출한 한약재 혼합추출물의 투여로 정상수준은 아니었지만 34% 낮아졌다(p<0.0.5). 혈장 내 지질과산화물 함량은 정상군과 당뇨 유도군 간에 유의한 차이는 없었으나, 간 마이크로좀의 지질과산화물 함량은 정상군은 6.20±2.25 n㏖/㎎ protein에 비하여 당뇨군은 7.74 n㏖/㎎ protein로 p<0.05 수준에서 높았다. 그러나 100 g의 홍화씨를 첨가하여 만든 한약재 혼합추출물 투여했을 때 5.85 n㏖/㎎ protein 수준까지 낮추어 주었다. 혈액과 간 조직 내 중성지방 함량은 역시 100 g의 홍화씨를 첨가하여 만든 한약재 혼합추출물 투여로 p<0.05 수준에서 저하효과가 현저하였다(p<0.05). 그러나 혈액과 간 조직 내 유리지방산, 총콜레스테롤과 인지질함량은 실험 전 군에서 유의적인 차이를 볼 수 없었고, 정상군에 비하여 당뇨군에서 혈장내 LDL-콜레스테롤과 동맥경화지수가 유의적으로 높은 반면에 HDL-콜레스테롤은 낮았으며 홍화씨와 한약재 혼합추출물이 이들 함량 변화에 미치는 효과는 관찰되지 않았다. 이상의 본 실험결과는 당뇨에 의한 혈당, 지질과산화물 그리고 중성지방 증가는 홍화씨와 한약재 혼합추출물의 투여로 다소 완화되었다. 이러한 결과를 바탕으로 체내 혈당조절에 의한 당뇨병의 예방 및 치유효과가 있는 홍화씨와 같은 천연물질의 기능성 성분에 대하여 향후에 보다 심층 있는 연구를 통하여 건강 기능성 식품 소재로 활용하는 것이 매우 중요할 것으로 여겨진다. The aim of the present study was to investigate the effect of combined extract of safflower seed with herbs on the improvement of blood glucose, lipid peroxides, lipids in the plasma and liver of strpetozotocin-induced diabetic rats. Rats in the experimental group were orally administered with combined extract of safflower seed (100 ㎎, 200 ㎎/㎏ B.W.) with herbs (Ophiopogon japonicus Ker-Gaqler, Glycyrrhiza uralensis Fisch, Mori Folium, Poria cocos, Rehmannia glutinosa, Eriobtrya japonica, Aralia continentalis Kitagawa, Zizyphus jujuba var, Cornus officinalis, Paeonia suffruticosa, Trichosanthes kirilowii Maxim and Schizandra chinensis Baill) for 4 weeks. Body weight gain and food efficiency ratio were significantly lower in diabetic groups than those of control group. These were no protective effect of the supplementation of combined extract of safflower seed with herbs. Concentration of blood glucose was significantly higher in the diabetic groups than those in the control group. Blood glucose concentration was remarkably lower supplementation of combined extract of safflower seed (200 ㎎/㎏ B.W.) with herbs. There was no significant difference of plasma lipid peroxides among experimental groups, while liver lipid peroxides of diabetic group was significantly higher in control group. But supplementation of combined extract of safflower seed with herbs was induced markedly lower in liver lipid peroxides in diabetic rats. Diabetic groups had markedly higher levels in triglycerides, LDL-cholesterol and atherogenic index, while had lower HDL-cholesterol level. Triglyceride levels of plasma and liver were significantly lower with combined extract of safflower seed with herbs. But total cholesterol, phospholipid and free fatty acid were no differing significantly among experimental groups.