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장우선(Woo-Sun Jang),정지승(Jee-Seung Chung),안영수(Young-Soo Ahn),윤식재(Sik-Jae Yoon),양성돈(Seong-Don Yang),박경준(Gyeong-Jun Park) 한국철도학회 2010 한국철도학회 학술발표대회논문집 Vol.2010 No.7
Tubular member is hollow and is an excellent source of structural member with great buckling resistance and tortional resistance. With its development and simplicity in structure, steel tubular truss has the ability to be structured in long span bridges, without a stiffener. Recently, it has been used in many countries in Europe, Canada, Japan, and the US with the help of international committees such as CIDECT(International Committee for the Development and Study of Tubular Structures and International Institute of Welding). The most important problem when using the tubular member is the fact that it is difficult to test the fatigue stress determined by nominal stress, since geometrical stress concentration occurs due to the welded joint`s nod of complexity. The purpose of this study is to compare and examine current theories and widely applied Hot Spot stress determinations through finite element analysis, which is about welded joints of steel tubular truss. We would like to suggest a way of design practice which involves a bridge plan with rarely domestically used steel tubular truss` basic research data as well as considering the future of tubular member.
장우선 ( Woo Sun Jang ),김찬웅 ( Chan Woong Kim ),김성은 ( Sung Eun Kim ),김범준 ( Beom Joon Kim ),김명나 ( Myeung Nam Kim ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.11
Background: Alcohol intake induces complex changes in the human body. However, there has not been much investigation on the interaction between alcohol and human skin. Objective: The aim of this study is to investigate the effects of alcohol intake on the skin`s physiology. Methods: A total 16 Korean males was enrolled in this study and they were divided into two groups (group A and group B). Each group included 8 people. Group A drank alcohol (20.1%, 360 ml) for 90 min and Group B drank 360 ml of normal saline. The body temperature, the skin erythema index, the transepidermal water loss (TEWL), the skin hydration, the skin pH and skin sebum were measured before and 30 min and 120 min after alcohol intake. Results: In group A, the skin erythema index, TEWL, skin hydration and skin pH significantly increased 30 min after alcohol intake, while the body temperature and sebum decreased. All the measurements except sebum recovered 120 min after alcohol intake. However, in group B, all the measurements were not significantly changed. Conclusion: Alcohol intake affects thermoregulation, the skin barrier function and the skin pH. This study showing that physiologic changes are induced by alcohol intake may help investigate the interaction between alcohol and skin disease. (Korean J Dermatol 2010;48(11):948∼954)
NC/Nga 마우스에서의 아토피피부염 유사 병변에 대한 Light Emitting Diode의 치료 효과
임윤영 ( Yun Young Lim ),장우선 ( Woo Sun Jang ),김형미 ( Hyeong Mi Kim ),김인수 ( In Su Kim ),이진웅 ( Jin Woong Lee ),김명남 ( Myeung Nam Kim ),김범준 ( Beom Joon Kim ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.3
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. It is caused by immunological abnormalities, abnormalities of the skin barrier, and environmental/ genetic factors. We did a preclinical trial to identify the effects of the 633-nm light- emitting diode (LED) and 830-nm LED for AD-like lesions in NC/Nga mice. Methods: AD-like skin lesions were induced by topical application of Dermatophagoides farinae extract on the skin of 5-week-old NC/Nga mice for 2 weeks, and then was treated with 630-nm or 830-nm LED for 1 week. We identified any therapeutic effects on AD using modified SCORAD index, skin biopsy, and measurements of both transepidermal water loss (TEWL) and proinflammatory cytokines. Results: Both of 630-nm and 830-nm LED treatment groups showed significantly reduced SCORAD indices and TEWLs at the end of treatment, compared to the non-treatment group. In addition, the levels of proinflammatory cytokine levels in both of the LED treatment groups were significantly decreased compared to those in the non-treatment group. Conclusion: These results show that 633-nm and 830-nm LED treatments can improve -like lesions in NC/Nga mice. (Korean J Asthma Allergy Clin Immunol 2011;31:207-214)
김인수 ( In Su Kim ),장우선 ( Woo Sun Jang ),이진웅 ( Jin Woong Lee ),박귀영 ( Kui Young Park ),이갑석 ( Kap Sok Li ),김범준 ( Beom Joon Kim ),서성준 ( Seong Jun Seo ),김명남 ( Myeung Nam Kim ),홍창권 ( Chang Kwun Hong ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.9
Cutaneous manifestations of secondary syphilis vary widely. Clinicians learn to consider the "great imitator" when confronting a combination of signs and symptoms that cannot be readily explained. A 29-year-old man presented with a 3-month history of well-circumscribed, scale-covered, erythematous plaque on the proximal part of his penis. On the basis of a serologic test for syphilis and skin biopsy, syphilid was confirmed. We report an unusual case of syphilid that presented with localized penile involvement presenting as a sole manifestation. (Korean J Dermatol 2011;49(9):859~861)
손인평 ( In Pyeong Son ),장우선 ( Woo Sun Jang ),이진웅 ( Jin Woong Lee ),김범준 ( Beom Joon Kim ),김명남 ( Myeung Nam Kim ),송계용 ( Kye Yong Song ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.4
Primary cutaneous mucinous carcinoma is a rare epithelial neoplasm that arises from the deepest portion of the eccrine duct. It most commonly occurs on the scalp and face with a preference for on the eyelids. The histopathologic characteristics are large mucinous pools with fibrous septae and clusters of tumor cells. We report here on a case of mucinous carcinoma that developed on the abdomen of a 47-year-old woman. (Korean J Dermatol 2011;49(4):348∼352)
이호(Ho Lee),권오식(O Sik Kwon),장우선(Woo Sun Jang),김승진(Seung Jin Kim) 한국철도학회 2016 한국철도학회 학술발표대회논문집 Vol.2016 No.5
운영중인 정거장 하부를 입체 교차하는 정거장을 계획함에 있어서 기존 정거장으로 인해 단절된 대합실을 연결하는 연결통로와 최단거리 환승을 고려한 승강장은 이용자의 편의성, 기존 정거장 기초의 안정성 및 시공성을 확보하기 위해 비개착공법을 계획하였다. 상세 지반조사 결과 입체적인 지반특성을 분석하고 정거장 기초의 시공현황을 설계에 반영하여 최적의 비개착공법을 적용하였다. 연결통로에 적용한 비개착공법은 이용자의 편의성을 고려하여 구조체 개념의 UPRS공법을 적용하고 승강장에 적용한 비개착공법은 기존 정거장 기초의 안정성 확보와 시공성을 고려하여 지보재 개념의 HUS공법을 적용하였다. 운영중인 정거장과 비개착공법의 안정성 확보를 위해 적용연장은 최단거리로 계획하고, 하중영향, 굴착영향, 지하수영향을 모두 고려한 기초의 안정성 평가를 수행하였으며, 시공단계를 고려한 모형시험, 3차원 수치해석을 수행하여 적정성을 검증하였다. The purpose of this study is planning a station which has a multi-level crossing with the existing station. A passageway to the waiting area and the shortest transfer were considered and to secure convenience of platform users, stability of the existing station’s foundation and constructability, non-open cut method was planned. To apply optimum non-open cut method, 3-dimensional ground properties were analyzed and construction status of station’s foundation was reflected in planning. In consideration of user’s usability, UPRS is applied to non-open cut method for a passageway. HUS is applied to non-open cut method for a platform in consideration of securing constructability and stability of the exiting station’s foundation. In order to procure stability of an operating station and non-open cut method, the shortest extension was designed. For foundation stability evaluation considering load effect, excavation effect and groundwater effect, three-dimensional numerical analysis with the consideration of construction phase and model test were performed.
StoneTouch(R) 적외선조사기를 이용한 동물 모델에서의 피부 안전성 시험과 아토피피부염의 증상개선 효과에 관한 연구
임윤영 ( Yun Young Lim ),김형미 ( Hyeong Mi Kim ),장우선 ( Woo Sun Jang ),서수홍 ( Soo Hong Seo ),안효현 ( Hyo Hyun Ahn ),김명남 ( Myeung Nam Kim ),김범준 ( Beom Joon Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.3
Background: Atopic dermatitis is a chronic inflammatory skin disease. It is caused by immunological abnormalities, abnormalities of the skin barrier, environmental factors and genetic factors. Atopic dermatitis destroys the skin barrier and passes through the skin, triggering an immune response. To treat atopic dermatitis, we anticipate use of hypoallergenic cures to hydrate skin that has been dried by destruction of the skin barrier. Objective: We did a preclinical trial to identify inhibitory effects of the StoneTouch(R) infrared scanner on atopic dermatitis. We conducted skin safety tests, comparing the use of infrared energy to drug treatment. We then confirmed the effects of the StoneTouch(R) infrared scanner through animal tests using Nc/Nga mice as a model of atopic dermatitis in order to identify any inhibition of the immune response in atopic dermatitis. Methods: We irradiated Nc/Nga mice using a StoneTouch(R) infrared scanner under a variety of conditions. During skin safety tests of the StoneTouch(R) infrared scanner on hairless mice, we assessed immune response and burn risk in irradiated mouse skin. We identified any inhibitory effects on atopic dermatitis using Dermoscope assessments, measurements of transepidermal water loss (TEWL) and IgE levels, measurements of pro-inflammatory cytokines, H&E staining and immunofluorescence staining (IF) of substance P and CGRP as neurotransmitters on the backs and ears of Nc/Nga mice irradiated by the StoneTouch(R) infrared scanner. Results: We did not observe any skin abnormalities after using the StoneTouch(R) infrared scanner on Nc/Nga mice. We confirmed the inhibitory effect of the StoneTouch(R) infrared scanner irradiation on atopic dermatitis. We found that irradiated epidermis was thinner than that of the epidermis in Nc/Nga mice in which atopic dermatitis was induced. We observed no significant between groups differences in expression level of substance P. The expression of CGRP in mice with atopic dermatitis was decreased, but, the increased irradiation led to greater expression of CGRP in irradiated skin. Conclusion: The StoneTouch(R) infrared scanner does not as a function of irradiation dosage. It inhibits the development of atopic dermatitis. (Korean J Dermatol 2011;49(3):217∼226)
박복남(Bok-Nam Park),방태환(Tae-Whan Bang),김종룡(Jong-Ryong Kim),장우선(Woo-Sun Jang),최성휴(Sung-Hyu Choe) 한국진공학회(ASCT) 1996 Applied Science and Convergence Technology Vol.5 No.3
서냉법과 용액성장법으로 HgS 및 HgS:Co 결정과 박막을 성장시켜서 결정구조를 조사하고, 광흡수를 측정했다. 이들 결정 및 박막은 육방정계 구조로써 HgS 및 HgS:Co결정의 격자상수는 각각 a。=4.155Å, c。=9.505Å과 a。=4.148Å, c。=9.487Å 이었다. 또한, HgS 및 HgS박막에 대한 격자상수는 각각 a。=4.14Å, c。=9.462Å와 a。=4.135Å, c。=9.422Å으로 주어졌다. 293 K에서 측정된 광학적 에너지 간격은 HgS 및 HgS: Co 결정이 2.040 eV, 1.900 eV 이고, HgS 및 HgS:Co 박막은 2.440, 1.940 eV 로 각각 주어졌다. HgS and HgS:Co crystals and films grown by the slow cooling and the chemical bath deposition method were used to measure their crystal structure and their optical absorption spectra. HgS and HgS:Co crystals are hexagonal structure with the lattice constant a。=4.155Å, c。=9.505Å for HgS and, a。=4.148Å, c。=9.487Å for HgS:Co. HgS and HgS:Co films are also hexagonal structure with the lattice constant a。=4.140Å, c。=9.462Å for HgS and a。=4.135Å, c。=9.442Å for HgS:Co, respectively. The optical energy gap of these crystals are given as 2.040 eV for HgS and 1.900 eV for HgS:Co, and the optical energy gap of these films were 2.440 eV for HgS and 1.940 eV for HgS:Co at room temperature, respectively.