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RISS 인기검색어
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- 저자 : 임석병(Seok-Byung Lim) (검색결과 4 건)
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Sae Byul Lee(이새별),Seok-Byung Lim(임석병) 대한종양외과학회 2012 Korean Journal of Clinical Oncology Vol.8 No.2
목적 : 근치적절제술을 시행 받은 결장직장암 환자의 폐 전이의 진단 및 치료에 있어서 흉부방사선촬영과 흉부 및 복부골반컴퓨터단층촬영의 임상적 가치에 대한 평가를 알아보고자 하였다. 대상 및 방법 : 근치적절제술을 받은 후 흉부컴퓨터단층촬영을 통해 폐 전이가 최종 확진된 247명의 환자를 대상으로 하였다. 흉부방사선촬영 및 복부골반컴퓨터단층촬영을 통해 폐 전이를 진단받은 환자들의 정확한 폐 전이 양상을 확인하기 위해 흉부컴퓨터단층촬영을 시행하였다. 결과 : 흉부방사선촬영의 폐 전이 진단율과 정확도는 각각 64.4%, 49.0%였으며 복부골반컴퓨터단층촬영의 폐 전이 진단율과 정확도는 각각 54.3%, 37.9%였다. 폐 전이의 절제율과 3년 생존율은 폐 전이의 양상에 따라 유의한 차이를 보였다. (절제율 : 단일 74.8%, 다중 14.2%, p<0.001, 3년생존율 : 단일 67.9%, 다중 27.1%, p<0.001). 결론 : 흉부컴퓨터단층촬영을 통해 폐 전이에 대한 정확한 정보를 얻어 진단 및 예후에 활용할 수 있다. 근치적절제술을 시행 받은 결장직장암 환자에 있어 흉부컴퓨터단층촬영을 포함한 추적관찰이 권유된다. Purpose : To evaluate the clinical value of chest CT compared to chest X-ray and abdominopelvic CT in diagnosis and management of pulmonary metastasis for colorectal cancer patients underwent curative resection. Materials and methods : The records of 247 patients with pulmonary metastasis confirmed by chest CT after curative surgery were reviewed. On the basis of chest CT findings, the detection and the accuracy rates for diagnosis of patterns of pulmonary metastasis [single (unilateral single) vs. multiple (unilateral > 2 or bilateral)] of chest X-ray and abdominopelvic CT were compared. The management methods and oncologic results according to the pattern were analyzed. Results : The detection and the accuracy rates for diagnosis of the pattern of metastasis of chest X-ray were 64.4% and 49.0%, respectively. Those of abdominopelvic CT were 54.3% and 37.9%, respectively. The rates of surgical resection for pulmonary metastasis and 3-year oveall survival rates were different according to the pattern of metastasis (resection : single 74.8%, multiple 14.2%, p<0.001, 3-year OS : single 67.9%, multiple 27.1 %, p<0.001). Conclusion : Chest CT could provide more accurate information on pulmonary metastasis, and it could affect the management methods and the prognosis. A follow-up program including chest CT should be considered after curative resection in colorectal cancer patients.
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절제 불가능한 전이가 동반된 4기 대장암 환자의 고식적 복강경 대장절제
양관모(Kwan Mo Yang),임석병(Seok-Byung Lim),윤용식(Yong Sik Yoon),김찬욱(Chan Wook Kim),박인자(In Ja Park),유창식(Chang Sik Yu),김진천(Jin Cheon Kim) 대한종양외과학회 2013 Korean Journal of Clinical Oncology Vol.9 No.2
Purpose: This study aimed to evaluate role of palliative laparoscopic colorectal resection for patients with stage IV colorectal cancer with unresectable metastasis. Methods: We reviewed 248 patients with stage IV colorectal cancer who underwent palliative bowel resection of the primary tumor during the period from January 2008 to December 2010 at Asan Medical Center. The short-term and oncologic outcomes of those with laparoscopic resection were reviewed and comparison was made between patients with laparoscopic and open resection. Results: A total of 248 patients were identified and of these patients, 50 underwent laparoscopic resection and conversion was required in six patients (12.0%). There was no differences in the gender, age, the location of primary tumor. But in the open group, peritoneal seeding was more (31.8% vs. 14.3%) and lung metastasis was less (28.3% vs. 48.0%; P=0.023) than laparoscopic group. The length of postoperative hospital stay in the laparoscopic group was significantly shorter than that in the open group (10.4 days vs. 6.7 days; P=0.048), and the postoperative complications were no significant difference in the both groups (13.1% vs. 8.0%; P=0.466) The overall survivals were similar in the both groups (mean survival, 758 days vs. 851 days; P=0.278). Conclusion: Considering of the patient’s general condition and distant metastasis, laparoscopic palliative bowel resection for stage IV colorectal cancer with unresectable metastasis is effective and safe.
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자기공명영상 기반의 임상병기 T3N0 직장암 환자에서 수술 전 항암방사선 치료의 무작위적 사용은 적절한가?
김지연(Jee Yeon Kim),박인자(In Ja Park),유창식(Chang Sik Yu),임석병(Seok-Byung Lim),이종률(Jong Lyul Lee),윤용식(Yong Sik Yoon),김찬욱(Chan Wook Kim),김진천(Jin Cheon Kim) 대한종양외과학회 2014 Korean Journal of Clinical Oncology Vol.10 No.1
Purpose: Preoperative chemoradiotherapy (PCRT) has been widely adopted. However, benefit of PCRT for patients with clinically T3N0 (cT3N0) rectal cancer is doubtful. We analyzed oncologic outcome in patients with magnetic resonance image (MRI) staged cT3N0 rectal cancer according to receipt of PCRT. Methods: Between January 2006 and December 2010, one hundred twenty four patients were MRI-based T3N0 rectal cancer. In patients who received PCRT the median dose of given radiotherapy was 5,040 Gy, and either 5-fluorouracil/leucovorin, capecitabine or S-1/oxaliplatin was delivered. The 3-year disease free survival rate (DFS) and sphincter preservation were compared. Results: Sixty four patients received and sixty patients did not receive PCRT. Rate of complete remission was obtained in 17.2% of PCRT group. Sphincter-preserving surgery was performed in 79.7% of PCRT group and 88.3% of non-PCRT group (P=0.194). In patients with low-lying rectal cancer, sphincter-preservation was also not different; PCRT 70.5% and non-PCRT 66.7% (P=0.761). Overall recurrence occurred in 21.9% in PCRT group and 15.0% in non-PCRT group (P=0.327). Three-year DFS was comparable between PCRT (76.5%) and non- PCRT group (79.7%) (P=0.330). Conclusion: Preoperative chemoradiotherapy in MRI-based cT3N0 rectal cancer had no benefit on sphincter preservation and did not improve DFS. Therefore, the routine use of PCRT in cT3N0 rectal cancer should not be warranted.
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대장암의 근치적 절제술 후 발생한 이시성 간전이에 대한 고주파 온열치료와 절제술의 장기 종양학적 결과 비교
이현구(Hyun Gu Lee),이병철(Byoung Chul Lee),박인자(In Ja Park),김소연(So Yeon Kim),김기훈(Ki-Hun Kim),하태용(Tae Yong Ha),이재훈(Jae Hoon Lee),김찬욱(Chan Wook Kim),이종률(Jong Lyul Lee),윤용식(Yong Sik Yoon),임석병(Seok-Byung Lim),유 대한종양외과학회 2016 Korean Journal of Clinical Oncology Vol.12 No.1
Purpose: We compared oncologic outcomes between surgery and radiofrequency ablation (RFA) in patients with metachronous isolated hepatic metastases from colorectal cancer. Methods: We retrospectively analyzed 123 patients treated with hepatic resection and 82 patients treated with RFA for metachronous hepatic metastases between April 2000 and October 2011. Re-recurrence pattern and 3-year re-recurrence free survival (RFS) rate compared between groups. Factors associated with RFS were evaluated. Results: The patients in the two groups were similar in age, gender, location of primary tumor, disease-free interval to hepatic metastasis, pathological stage of primary disease, number of metastatic lesions. The mean diameter of the biggest hepatic metastatic lesion was significantly larger in the resection group than in the RFA group. The RFS rate after hepatic metastasis treatment was significantly higher in the resection group than in the RFA group (48.6% vs. 33.7%, respectively; P=0.015). Marginal recurrence at the RFA site was observed in 14 of the 82 patients (17.1%). The size and number of metastatic lesions, stage of primary disease, disease-free interval to hepatic metastasis, and modality of treatment were confirmed as re-recurrence-associated factors after hepatic metastasis treatment. Among patients with solitary metastases of ≤3 cm, the RFS rate was not different between the resection and RFA groups (52.4% vs. 53.4%, respectively; P=0.491). Conclusion: Surgical resection for metachronous hepatic metastases achieved higher RFS and lower local recurrence rates. However, the RFS rate in patients with a solitary hepatic metastasis of ≤3 cm was similar between the resection and RFA groups.
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