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      • KCI등재

        신문혈(神門穴) 침자극(鍼刺戟)이 모성분리(母性分離) 흰쥐의 대뇌(大腦) 변연계(邊緣系)의 c-Fos 발현(發顯)에 미치는 영향(影響)

        임사비나,황세희,류연희,이혜정,박히준,Lim, Sabina,Hwang, Se-Hee,Ryu, Yeun-Hee,Lee, Hye-Jung,Park, Hi-Joon 경락경혈학회 2004 대한침구의학회지 Vol.21 No.3

        Acupuncture has been shown to have therapeutic effects on many mental disorders such as depression, anxiety, and substance abuse in human and animal studies. Maternal separation (MS) is a risk factor in the development of mood-related disorders such as depression. This study investigated the effects of acupuncture during MS by evaluating locomotion as behavioral markers of depression and by observing changes in c-Fos expression in the limbic system (hippocampus, amygdala and cingulate cortex) to elucidate the mechanism of the therapeutic effect. The employed acupoint, Shinmun (HT7), has been clinically used to treat mental disorders. MS for 7 days beginning on postnatal day 14 induced a significant decrease in locomotion, while acupuncture treatment at acupoint HT7 resulted in a significant increase in locomotion. c-Fos immunoreactive cells in area dentate gyrus (DG) of the hippocampus were increased in the MS group, but significantly decreased in the acupuncture group. These findings suggest that acupuncture has an effect on the depression-like disorder caused by MS, possibly by modulating c-Fos expression in DC of the hippocampus.

      • KCI등재

        영추·경맥편 수태음폐경 유주의 한글번역에 대한 고찰

        정혜진,임사비나,Jung, Hyejin,Lim, Sabina 경락경혈학회 2016 Korean Journal of Acupuncture Vol.33 No.3

        Objectives : It aims to establish a basic rule in Korean translation of the pathway of lung meridian in Miraculous Pivot Meridian vessel. Based on the rule, We tried to make standard translation of the pathway of lung meridian in Miraculous Pivot Meridian vessel. Methods : Books needed for this study were collected through searching Kyunghee University Library(http:// khis.khu.ac.kr). Keywords included "Miraculous Pivot of Huangdi's Internal Classic". We also include the book which is generally used as a textbook in Colleges of Korean Medicine. Results : In five Chinese books, the word-spacing was used differently in four phrases. Six Korean-translated books had the different translation in three phrases. We suggested a standard Korean translation of the pathway of lung meridian in Miraculous Pivot Meridian vessel. Conclusions : This result of the study would be expected to not only be published in Korean Journal of Acupuncture but be studied more about Korean translation by experts in this field.

      • KCI등재

        식이섬유 수준이 유색육용계의 육질에 미치는 영향

        김미숙,문윤희,임사비나,김대진,Kim, Mi-Suk,Moon, Yoon-Hee,Lim, Sabina,Kim, Dae-Jin 한국생명과학회 1997 생명과학회지 Vol.7 No.4

        This study was conducted to investigate the effect of dietary fiber(DF) levels on the meat quality in colored broiler. Colored broiler were fed on containing corn-soy basal diet(DF 5%) and high level(DF 6,7 and 8%) of dietary fiber diets for 7 weeks. Dietary fiber level of diet was make up by adding some alffalfa meal. Colored broiler meats were stored at 3$\circ$ for 24hr after skaughter, and used to analyze physico-chemical properties. Proximate component, pH, shear force value, myofibril fragmentation index, water holding capacity, cooking loss, protein extractability, fatty acid composition, Hunter's L, a value and palatability of cooked meat were not significantly affected by dietary fiber levels, whereas the Hunter's value of meat was significantly affected bty dietary fiber levels for the final period of feeding. Crude protein content, myofibril fragmentation index, water holding capacity, protein extractability and Hunter's b value of breast meat's were higher than thigh meat's, but crude fat content, pH, shear force value, cooking loss, palmitoleic acid, linolenic acid, and Hunter's a value were lower, regardless of dietary fiber level.

      • KCI등재

        The Effects of Herbal Acupuncture on Immuno-regulatory Action of the Hypothalamus in Rats

        이태후,박히준,임사비나,Lee Tae-Hoo,Park Hi-Joon,Lim Sabina 경락경혈학회 2003 Korean Journal of Acupuncture Vol.20 No.2

        목적 : 본 연구는 염증유발 내독소인 LPS 자극을 통한 면역 스트레스에 대한 약침의 치료효과와 기전을 알아보기 위해 설계되었다. LPS를 통한 염증반응은 다양한 기전을 통해 이루어지는 데 특히, 산화질소(NO)를 생성하는 효소인 iNOS의 활성은 시상하부에서 NO의 생성을 촉진함으로써 염증반응을 발현시키는 중요한 역할을 하는데 약침이 LPS로 인해 활성화된 iNOS의 발현에 어떠한 영향을 미치는지 알아보고자 하였다. 실험방법 : 흰쥐에 LPS를 투여하고 2시간 경과한 후 약침 (소염방, 대한약침학회)을 경혈 (합곡, 족삼리)에 좌,우 각각 0.2cc 씩 피하 투여하고 RT-PCR 방법을 통하여 면역활성에 중요한 역할을 하는 시상하부에서의 iNOS의 mRNA 발현을 알아 보았다. 실험결과 : LPS 투여로 인하여 증가하였던 iNOS mRNA가 약침치료를 통해 현저하게 감소하였다. 그러나 비경혈점 (미추부위 임의혈)에 약침을 투여한 군 경혈점에 생리식염수를 투여한 군에서는 iNOS mRNA 가 감소하지 않았다. 이는 약침이 LPS를 투여한 흰쥐의 시상하부에서 iNOS의 mRNA 발현에 조절작용을 가지고 있는 것을 보여주는 결과로 약침이 면역활성에 중요한 역할을 하는 NO의 생성을 억제함으로써 면역 스트레스에 치료효과를 나타내는 것으로 보여진다. 결론 : 본 연구는 약침치료가 면역반응의 중추기관인 시상하부에서 면역반응의 중요한 조절인자인 NO의 생성을 조절하는 기전을 통해 그 치료효과를 나타내는 것을 밝혔고 더 나아가 약침에 대한 현대과학적 연구에 중요한 발판을 마련했다는 점에서 그 의의를 가지고 있다고 사료된다.

      • KCI등재

        영추·경맥편 수태음폐경 유주의 한글번역에 대한 고찰

        정혜진 ( Hyejin Jung ),임사비나 ( Sabina Lim ) 대한경락경혈학회 2016 Korean Journal of Acupuncture Vol.33 No.3

        Objectives : It aims to establish a basic rule in Korean translation of the pathway of lung meridian in Miraculous Pivot · Meridian vessel. Based on the rule, We tried to make standard translation of the pathway of lung meridian in Miraculous Pivot · Meridian vessel. Methods : Books needed for this study were collected through searching Kyunghee University Library(http:// khis.khu.ac.kr). Keywords included “Miraculous Pivot of Huangdi’s Internal Classic”. We also include the book which is generally used as a textbook in Colleges of Korean Medicine. Results : In five Chinese books, the word-spacing was used differently in four phrases. Six Korean-translated books had the different translation in three phrases. We suggested a standard Korean translation of the pathway of lung meridian in Miraculous Pivot · Meridian vessel. Conclusions : This result of the study would be expected to not only be published in Korean Journal of Acupuncture but be studied more about Korean translation by experts in this field.

      • KCI등재후보
      • KCI등재

        보건의료용어표준 경혈명에 대한 고찰

        정혜진(Hyejin Jung),임사비나(Sabina Lim) 대한한의학회 2018 대한한의학회지 Vol.39 No.1

        Objectives: This study aims to investigate on the nomenclature of acupoints for the Healthcare Terminology Standard. Methods: We investigated the name of acupoints in 『Standard Acupuncture Nomenclature (Second Edition)』 of WHO, 『WHO Standard Acupuncture Point Locations in The Western Pacific Region』, 『Principles of Meridians & Acupoints』, 『Details of Meridians & Acupoints』 and 『Acupuncture Medicine』. Results: In books, we found that the name of acupoints was used differently in LI19, TE22, HT3, SI8, ST16, SI16, GB16 and BL8 acupoints. Conclusions: 口禾髎(LI19), 耳和髎(TE22), 少海(HT3), 小海(SI8), 膺窗(ST16), 天窗(SI16), 目窗(GB16), 絡卻(BL8) and 淵腋(GB22) in confused acupoints have been established as the terms of acupoints for the Healthcare Terminology Standard.

      • KCI등재

        신문혈(神門穴) 침자극(鍼刺戟)이 모성분리(母性分離) 스트레스로 야기된 섭식(攝食) 장애(障碍)와 시상하부 neuropeptide Y 발현에 미치는 영향

        박히준,류연희,홍미숙,김승태,임사비나,Park, Hi-joon,Ryu, Yeon-hee,Hong, Mee-suk,Kim, Seung-tae,Lim, Sabina 대한침구의학회 2003 대한침구의학회지 Vol.20 No.4

        Objective: The purpose of this study is to find out the effect of acupuncture at HT7 (Shinmun) on the feeding behavior and hypothalamic neuropeptide Y(NPY) expression in the maternally separated rat pups. Methods: To show the effect of acupuncture, we performed maternal separation(MS) for 7 days beginning on postnatal day 14, and observed body weight, food intake, and NPY immunoreactivity in the paraventricular nucleus (PVN) of hypothalamus after acupuncturing at HT7, the end of the transverse crease of the ulnar wrist of the forepaw. Results: MS induced a significant decreases in body weight and food intake, while acupuncture treatment at acupoint HT7 showed much more improvement in those evaluations. NPY-immunoreactivity in area PVN were decreased in the MS group, but significantly increased in the HT7 group. Conclusions: These findings suggest that acupuncture has an effect on the feeding disorders caused by MS, possibly by modulating NPY expression in the PVN.

      • KCI등재

        국내와 대만의 전통약제제 생산 · 허가 · 보험등재 관련 제도 비교 분석

        손지형(Son Chi-Hyoung),임사비나(Lim Sabina),이은경(Lee Eun-Kyoung),김동수(Kim Dong-su),김윤지(Kim Yun-Gi),정홍강(Huan-Chiang Cheng),김용호(Kim Yong-Ho) 대한한의학회 2012 대한한의학회지 Vol.33 No.3

        Objectives: Systems related to the production, authorization, and listing for insurance of herbal medicine products were compared between South Korea and Taiwan to illuminate herbal medicine products system issues in South Korea. Methods: Papers, and laws and policies related to the production, authorization, and listing for insurance of herbal medicine products in South Korea and Taiwan are analyzed to create the primary documents. The documents from South Korea were screened with the advice of a specialist, while those from Taiwan have been verified through local investigation and with the help of a related specialist. The screened documents were then compared and analyzed in the order of the systems related to the production, authorization, and listing for insurance of herbal medicine products. Results: The systems related to the production of herbal medicine products satisfy GMP requirements in both countries, while Taiwan has more specialized systems related to the production of herbal medicine products and a more strict authorization program as compared to South Korea. While South Korea has most of the herbal medicine products classified as non-prescription drugs, Taiwan has them as prescription drugs. And while South Korea does not allow new herbal medicine products to be listed for insurance, Taiwan allows for once-a-year application toward listing for insurance. Conclusions: In order to ensure the safe and effective use of herbal medicine products, systems related to the production, authorization, and listing for insurance of herbal medicine products are to be established, while the categorization of medicine products principally used by Korean medicine doctors should be prepared. Furthermore, prescription by a Korean medicine doctor for new drugs made with natural products and their listing for insurance need to be encouraged.

      • KCI등재

        만성두통 환자의 성격유형 A 행태, 스트레스, 우울 및 두통영향정도의 관계 연구

        차남현(Cha Nam-Hyun),임사비나(Lim Sabina),정인태(Jung In-Tae),김수영(Kim Su-Young),안경애(An Kyung-Ae),김건식(Kim Keon-Sik),이재동(Lee Jae-Dong),이상훈(Lee Sang-Hoon),최도영(Choi Do-Young),이윤호(Lee Yun-Ho),이두익(Lee Doo-Ik) 한국성인간호학회 2005 성인간호학회지 Vol.17 No.4

        Purpose: To examine an estimate factor and grasp the relation of difference for Type A Behavior Pattern(TABP), Perceived Stress Questionnaire, Depression and HIT-6 in the Chronic headache client. Method: Data collected by self-reported questionnaires from 38 client in S city who were selected by criteria of IHS, from the 19<SUP>th</SUP> of October to 10<SUP>th</SUP> of December, 2004. Result: 1) Differences between biographical data by TABP was significant by SaSang constitutions, by Stress was significantly influenced by age, and by Depression were significantly influenced health status and SaSang constitutions. 2) Correlations Coefficients among Study Variables were Stress and Depression(r=.494, p=.002) and Depression and HIT-6(r=.432, p=.010). 3) In regression analysis, HIT-6 were significantly influenced by Depression and Type A Behavior Pattern(TABP). These variables explained 38% and 34% respectively. Conclusion: The result suggest that chronic headache management with psychological aspect, as well as physical aspect should be a focus to enhance the quality of life.

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