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습열리(濕熱痢)로 변증한 궤양성 대장염 환자의 작약탕가미방(芍藥湯加味方) 치험 2례
이형호,최기숙,임동석,유형천,이영수,최창원,김희철,서철훈,Lee, Hyung-Ho,Choi, Ki-Suk,Lim, Dong-Seok,Ryu, Hyung-Chun,Lee, Young-Soo,Choi, Chang-Won,Kim, Hee-Chul,Seo, Chul-Hoon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.4
Ulcerative colitis, a diffuse inflammatory disease of the mucosal lining of the colon and rectum, is characterized by bloody diarrhea that waxes and wanes without apparent cause. In oriental medicine, Jakyaktang has been used to treat the disease, diagnosed as Damp-Heat dysentery. We prescribed Jakyaktang-gamibang to two patients who had suffered from ulcerative colitis diagnosed as Damp-Heat dysentery. The two patients were treated with Jakyaktang-gamibang and improved in consciousness of symptoms. We suggest that oriental medicine therapy is effective for treatment of ulcerative colitis.
자음양영탕이 Streptozotocin(STZ)로 유발된 생쥐의 고혈당에 미치는 영향(影響)
이형호,이영수,Lee, Hyung-Ho,Lee, Young-Soo 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3
Objectives : The aim of this study was to investigate the effect of Jaeumyangyung-tang(滋陰養榮場(JY), JA-0.65g/kg;JB-1.3g/kg) on hyperglycemic mice induced with streptozotocin(STZ). Methods : The experiment operated for 6 weeks. The rats were divided into 3 groups : diabetic group(control group), diabetic group treated with JA(0.65g/kg) for 6 weeks, and diabetic group treated with Jb(1.3g/kg) for 6 weeks. Results : In the STZ-induced diabetic group, blood glucose levels significantly increased as well as the loss of body weight. The levels of serum glucose decreased significantly (p<0.05 or p<0.01) in the JA and JB groups compared with the control. According to a tolerance test, intraperitoneal glucose was ameliorated in the JA and JB groups. The blood urea nitrogen (BUN) and creatinine levels slightly decreased. Histologic analyses of the pancreases revealed that the ${\beta}-cells$ on Langerhans' islets were destroyed by STZ, but the ${\beta}-cell$ mass was larger in the JY than in the control mice. Conclusions : These results indicate that JY can exert beneficial effects on diabetes. preservation of in vivo ${\beta}-cell$ function and regeneration of ${\beta}-cell$ dysfunction by STZ.
Caerulein으로 유발된 흰쥐의 급성 췌장염에 대한 은회반총산(銀茴蟠?散)의 효과
이형호,김인수,신민구,이영수,Lee, Hyung-Ho,Kim, In-Soo,Shin, Min-Gu,Lee, Young-Su 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.3
Objectives : In this study, we aimed to investigate the effect of Eunhoebanchong-san (EBS) on caerulein-induced acute pancreatitis (AP) by detecting oxidative stress markers and performing histopathological examination. Methods : Thirty adult male Sprague-Dawley rats were divided into five groups as follows: normal (NOR), caerulein-induced (CON), caerulein+EBS (130 mg/kg, EA), caerulein+EBS (260 mg/kg, EB) and caerulein+EBS (520 mg/kg, EC) groups. Pancreatic tissues of rats from all groups were removed for apoptosis, and light, and electron microscopic examination. Blood of rats from all groups was obtained for oxidative stress markers and pathological examination. Pancreatic oxidative stress markers were evaluated by the measurements of serum amylase, and interleukin-6 (IL-6) levels were determined spectrophotometrically. Results : The ratio of pancreas/body weight increased significantly in the CON compared with the NOR, but decreased significantly in the EA, the EB, the EC groups compared with the CON. Caerulein administration resulted in a significant increase in amylase, but EBS reduced the levels of these enzymes. Interleukin-6 (IL-6) levels increased significantly in CON compared with NOR, but reduced in EA, EB, and EC group at 24 hrs. In the observations of optical microscopy and electron microscopy, the experimental groups showed significant decreases in pancreatic tissue inflammation, edema, vacuolization, necrosis compared to the control group. Altogether, this indicates EBS is potentially capable of limiting pancreatic damage produced during AP by restoring the fine structure of acinar cells and tissue. Conclusions : We concluded that EBS may have beneficial effects in the treatment of caerulein-induced AP.
Robust and Non-fragile H∞ Controller Design for Tracking Servo of Blu-ray disc Drive System
이형호(Hyung Ho Lee),김준기(Joon Ki Kim),김원기(Woon Ki Kim),조상우(Sang Woo Jo),박홍배(Hong Bae Park) 대한전자공학회 2008 電子工學會論文誌-SC (System and control) Vol.45 No.3
본 논문에서는 blu-ray 디스크 드라이버의 트랙킹 서보시스템에 대하여 플랜트와 제어기의 불확실성을 보상하는 견실비약성 H∞ 상태궤환 제어기 설계방법을 제안한다. 플랜트와 제어기의 불확실성을 매개변수화 선형행렬부등식(PLMI : parameterized linear matrix inequality)을 이용하여 구조화된 불확실성의 형태로 표현하며, Lyapunov 함수를 이용하여 구조적인 제어기의 이득섭동을 고려한 견실비약성 H∞ 상태궤환 제어기가 존재할 충분조건 및 제어기 설계방법을 PLMI의 형태로 제안한다. 또한, 완화기법(relaxation technique)을 통하여 PLMI를 유한개의 LMI의 형태로 변환하여 견실하고 최적화된 제어기 이득과 제어기 섭동 범위를 계산하고, 모의실험을 통해서 제시된 제어기의 타당성 및 견실성(robustness)과 비약성 (non-fragility)을 검증한다. In this paper, we describe the synthesis of robust and non-fragile H∞ state feedback controllers for linear systems with affine parameter uncertain tracking servo system of blu-ray disc drive, as well as static state feedback controller with polytopic uncertainty. Similarity any other control system, the objective of the track-following system design for optical disc drives is to construct the system with better performance and robustness against modeling uncertainties and various disturbances. Also, the obtained condition can be rewritten as parameterized linear matrix inequalities (PLMIs), that is, LMIs whose coefficients are functions of a parameter confined to a compact set. We show that the resulting controller guarantees the asymptotic stability and disturbance attenuation of the closed loop system in spite of controller gain variations within a resulted polytopic region.
물체 특징과 실시간 학습 기반의 파티클 필터를 이용한이동 로봇에서의 강인한 물체 추적
이형호(Hyung-Ho Lee),최학남(Xuenan Cui),김형래(Hyoung-Rae Kim),마승완(Seong-Wan Ma),이재홍(Jae-Hong Lee),김학일(Hak-Il Kim) 제어로봇시스템학회 2012 제어·로봇·시스템학회 논문지 Vol.18 No.6
This paper proposes a robust object tracking algorithm using object features and on-line learning based particle filter for mobile robots. Mobile robots with a side-view camera have problems as camera jitter, illumination change, object shape variation and occlusion in variety environments. In order to overcome these problems, color histogram and HOG descriptor are fused for efficient representation of an object. Particle filter is used for robust object tracking with on-line learning method IPCA in non-linear environment. The validity of the proposed algorithm is revealed via experiments with DBs acquired in variety environment. The experiments show that the accuracy performance of particle filter using combined color and shape information associated with online learning (92.4 %) is more robust than that of particle filter using only color information (71.1 %) or particle filter using shape and color information without on-line learning (90.3 %).