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용육조위탕(龍肉調胃湯) 증류액이 노화 흰쥐 비장 세포의 면역활성에 미치는 영향
이진욱,장문희,최재송,안택원,Yi, Jin-Wook,Jang, Moon-Hee,Choi, Jae-Song,Ahn, Taek-Won 사상체질의학회 2013 사상체질의학회지 Vol.25 No.3
Objectives The purpose of this study was to investigate the effect of Yongyukjowitang(YJT) distillate on the immune activity of spleen cells of aged SD rats. Methods Spleen cells from 10w, 52w, 72w old rats were stimulated with Concanavalin A(Con A) and treated with Vitamin C(Vit.C) or Yongyukjowitang distillate(YJT). After 24 hours, levels of IL-2, IL-4, IL-10, IFN-${\gamma}$ were measured using ELISA in spleen cells. Results and Conclusions 1. The concentration of IL-2, IL-4 in spleen cells of 52 weeks old SD rats(YJT group) significantly decreased in comparison with ConA group. 2. The concentration of IFN-${\gamma}$ in spleen cells of 72 weeks old SD rats significantly increased in comparison with 10 weeks old SD rats(NT group), but decreased in comparison with 10 weeks old SD rats(YJT group). These results suggest that Yongyukjowitang distillate has an effect on the immune activity of spleen cells of aged SD rats.
이진욱(Jin Wook Yi),정인목(In Mok Jung),이태승(Taeseung Lee),민승기(Seung-Kee Min),민상일(Sang Il Min),박양진(Yang Jin Park),하종원(Jongwon Ha),정중기(Jung Kee Chung),김상준(Sang Joon Kim) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.6
Purpose: Acute ischemia of the arm is uncommon compared with events in the leg and much less attention has been paid to the management of acute arterial thromboembolism of the upper extremities. The aim of this study was to evaluate the clinical aspects and treatment outcomes of acute upper extremity thromboembolism. Methods: From January 2007 to March 2010, seven patients underwent the management of upper extremity thromboembolism in three Seoul National University (SNU)-affiliated hospitals. We retrospectively reviewed the medical records. Results: The mean age was 64.6 years (range 48∼93 years) and 4 patients (57.1%) were female. Distribution of the thromboembolism were 4 in brachial, 1 in axillary plus brachial, 1 in ulnar and radial, and 1 in axillary artery, respectively. Time from symptom onset to presentation was 3.5 days (range 1∼10 days). Primary treatment modality were Fogarty catheter embolectomy in 3 cases, bypass surgery in 1 case, and urokinase thrombolysis in 2 cases. A patient without symptoms was treated conservatively. Patients receiving primary thrombolytic therapy underwent surgical approach due to recurred thromboembolism during admission. In our 11.2 months of mean follow-up, there was recurrence but 1 patient died from cerebral infarction after 1.5 year of discharge. Conclusion: In this study, functional outcome of acute upper extremity ischemia following appropriate treatments was excellent. Key features of treatment are shortening the time interval of diagnosis to primary treatment, proper anticoagulation, and treatment of underlying conditions. Larger-volume, long-term results and meta-analysis of upper extremity thromboembolism are required to establish standardized treatment in Korea.
원격전이가 동반된 미세 침윤형 여포암 환자의 임상병리학적 양상
주영욱(Young Wook Ju),김수진(Su jin Kim),채영준(Young Jun Chai),이진욱(Jin Wook Yi),성찬용(Chan Yong Seong),김종규(Jong Kyu Kim),유형원(Hyeong Won Yu),최준영(June Young Choi),이규언(Kyu Eun Lee) 대한갑상선-내분비외과학회 2016 The Koreran journal of Endocrine Surgery Vol.16 No.4
Purpose: Although minimally invasive follicular thyroid carcinoma (MIFTC) is considered a thyroid tumor with low malignant potential, some MIFTC can spread, metastasize, and eventually lead to death. This study investigates the risk factors for distant metastasis in MIFTC patients. Methods: Between 1981 and 2014, the records of 365 consecutive patients who underwent thyroidectomy for MIFTC at Seoul National University Hospital were reviewed. Univariate and multivariate analyses were performed to identify risk factors associated with distant metastasis. Results: Of 351 patients, 10 (2.9%) presented with distant metastasis. Of these, two (0.6%) were found at the time of thyroidectomy, while eight (2.3%) were detected at later exams, over a median of 7.3 years (range, 0.2∼30.8). In univariate analysis, lymph node metastasis (P<0.001) was significantly associated with distant metastasis. In multivariate analysis, lymph node metastasis (P<0.001) and locoregional recurrence (P=0.008) were significantly associated with distant metastasis. Conclusion: Distant metastasis in MIFTC patients were associated with high-risk clinicopathologic features and more aggressive clinical courses. Further study will be needed to ascertain these results with long-term surveillance.
유상오(Sang Oh Yoo),이진욱(Jin Wook Lee),정석우(Seok Woo Chung),윤성필(Sung Pill Yoon),이재만(Jae Man Lee),이민회(Min Hoe Yi),임성광(Sung Kwang Lee) 한국에너지기후변화학회 2013 에너지기후변화학회지 Vol.8 No.1
Pulverized low rank coal for the utilization of fast fluidized bed gasification is larger in size and higher in moisture content compared to those of entrained bed gasification. So, coal transport might not be stable because of strong possibility of bridging in the injection vessel and plugging in the transport line. In this study we have been trying to develop the new technology to overcome such operational problems. As first step to develop such technology, series of pneumatic transport experiment have been performed using simple transport system which is consist of injection vessel and receiver tank. Characteristics of pneumatic transport of pulverized low rank coal have been studied under various operating conditions such as operating pressure, pressure difference between injection vessel and receive tank and so on.
컴팩트 석탄 가스화기 개발을 위한 이중선회버너 운전 평가
강석환,류재홍,정석우,정우현,유상오,이도연,윤용승,이진욱,김규태,이민회,Kang, Suk-Hwan,Ryu, Jae-Hong,Chung, Seok-Woo,Jung, Woo-Hyun,Yoo, Sang-Oh,Lee, Do-Yeon,Yun, Yongseung,Lee, Jin-Wook,Kim, Gyoo-Tae,Yi, Min-Hoe 한국에너지학회 2013 에너지공학 Vol.22 No.2
석탄가스화 기술은 청정석탄에너지 기술 중에서 아주 중요한 대안으로 인식되고 있으며, 이에 전 세계적으로 차세대 석탄가스화기라고 할 수 있는 고효율 저비용 석탄가스화기를 개발하고 있다. 본 연구에서도 이러한 목적의 달성을 위하여 저비용으로 구현이 가능한 컴팩트 석탄가스화기를 개발하고 있으며, 다수개의 공급부로 이루어진 일체형 이중선회형 버너를 개발하였다. 개발된 버너의 가스화 운전조건을 확보하기 위하여 미분탄 분배기와 함께 기존의 석탄가스화기 몸체에 설치하여 가스화 실험을 수행하였다. 인도네시아산 아역청탄인 ABK 탄을 사용하여 1.5톤/일의 파일럿 규모로 $6.4{\sim}7.2kg/cm^2$, $1170{\sim}1300^{\circ}C$ 조건에서 운전을 수행하였다. 우선 성능평가보다는 안정적인 가스화기 운전조건을 확보하는데 중점을 두었다. 그 결과, 안정적인 운전조건에서 탄소전환율은 84.0%, 냉가스 효율 52.1%를 확보할 수 있었다. Coal gasification is considered as one of the best alternatives among clean coal technology and new concept next generation technologies are under being developed to achieve low cost as well as high efficiency. In this study we have developed double swirl multi-burner as part of the development of low cost compact gasifier. We installed new concept multi-burner with pulverized coal distributor to the body of existing gasifier for burner test. Gasification test was performed under the condition of $6.4{\sim}7.2kg/cm^2$ and $1170{\sim}1300^{\circ}C$ by using Indonesian ABK (sub-bituminous) coal to get operation condition of new concept multi-burner. Our interest was focused to ensure a stable operating condition rather than the gasifier performance evaluation. As a result, we were able to achieve the carbon conversion of 84% and the cold gas efficiency of 52.1% at the stable operating conditions.
김영민(Young Min Kim),김수진(Su jin Kim),이진욱(Jin Wook Yi),성찬용(Chan Yong Seong),김종규(Jong Kyu Kim),유형원(Hyeong Won Yu),채영준(Young Jun Chai),최준영(June Young Choi),이규언(Kyu Eun Lee) 대한갑상선-내분비외과학회 2016 The Koreran journal of Endocrine Surgery Vol.16 No.4
Purpose: Postoperative adhesion after thyroidectomy results in neck discomfort and swallowing difficulty. However, risk factors for adhesive symptom after thyroidectomy have not been well studied. This study evaluated symptoms related to postoperative adhesion after thyroidectomy. Methods: The Glasgow-Edinburgh Throat Scale (GETS) questionnaire was used to evaluate postoperative adhesion. Patients who completed the GETS questionnaire either pre- or post- operatively were enrolled. Patient clinical and pathological details including age, gender, body weight, body mass index (BMI), tumor size, thyroid volume, extent of thyroidectomy, postoperative months, and neck thickness on ultrasonography and computed tomography (CT) were abstracted. Results: Twenty-eight preoperative (22 females, six males) and 101 postoperative (83 females, 18 males) patients were enrolled. The mean age of the pre-operative enrollees was 52.1±11.7, and of post-operative enrollees 51.8±12.4 years. Patients who were within one month post-surgery had higher GETS scores than preoperative patients (27.4±20.1 vs. 6.5±11.1, P<0.001). Two months after surgery, GETS scores of postoperative patients did not differ significantly from the scores of the preoperative patients. There were no significant associations between clinical and pathologic features (age, tumor size, BMI, neck thickness on ultrasonography and CT) and GETS scores. Conclusion: Postoperative adhesive symptoms were most severe at one month after surgery, while questionnaire scores two months after surgery were comparable with preoperative patients. Further studies will be required for better understanding of the natural course of postoperative adhesion after thyroidectomy.