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만성 C형 간염에서 B형 간염 바이러스의 잠재감염: 단순 방관자 아니면 어떤 역할?
이준성 ( June Sung Lee ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6
Occult hepatitis B virus (HBV) infection is defined as the presence of HBV DNA in the liver (with or without detectable HBV DNA in serum) for individuals testing HBV surface antigen negative. Until recently, the clinical implication of occult HBV infection was unclear. Several studies suggest a high prevalence of occult HBV infection among patients with chronic liver disease. Occult HBV infection is a complex entity comprising many conditions and situations that may be widely different from the biological point of view and clinical consequences. Data regarding natural course and therapy in chronic hepatitis C patients with occult HBV are limited and based on small case numbers. These considerations imply the need for a critical re-evaluation of this field to define better strategies to diagnose and treat this infection. (Korean J Med 2012;83:728-730)
만성 간질환 치료의 최신 지견 ; 간세포암종 치료의 최신 지견
이준성 ( June Sung Lee ) 대한내과학회 2009 대한내과학회지 Vol.77 No.3
There have been recent advances in the treatment of hepatocellular carcinoma (HCC). There has been a clear change in the presentation of HCC, with an increased detection of tumors <2 cm in diameter as result of surveillance programs. In addition, the development of effective local treatment methods has led to the necessity for the selection of base therapeutic modalities on each patient`s characteristics. New promising image-guided therapies and new drugs, such as sorafenib, may address the enormous need for expanded treatment options for patients with HCC. Tailored therapies are needed to improve the treatment response and, ultimately, patient survival. Here, we review these advances in the management of HCC. (Korean J Med 77:290-297, 2009)
이준성 ( June Sung Lee ) 대한내과학회 2013 대한내과학회지 Vol.84 No.3
Cystic lesions of the liver in the adult can be classified as developmental, neoplastic, inflammatory, or miscellaneous. They occur in symptomatic or asymptomatic patients with or without preexisting liver disease. Many of the lesions represent a diagnostic dilemma for the clinician and usually a single imaging study is not diagnostic. The physician must understand the clinical, radiologic, and pathologic characteristics of these cystic lesions including benign lesion such as simple (bile duct) cyst, autosomal dominant polycystic liver disease, biliary hamartoma, Caroli disease, congenital hepatic fibrosis, and premalignant lesion such as biliary cystadenoma and cystadenocarcinoma. In this review, we review the clinical, radiological, and histologic features of the most common benign cystic liver disease and also present current management options. An understanding of these facts will allow more definitive diagnosis and shorten the diagnostic workup for focal cystic liver lesions. (Korean J Med 2013;84:341-345)
이준성 ( June Sung Lee ),김경아 ( Kyung Ah Kim ),이우진 ( Woo Jin Lee ),전영빈 ( Young Bin Jeon ),이정환 ( Jung Whan Lee ),김유선 ( You Sun Kim ),문정섭 ( Jeong Seop Moon ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.2
Backgrounds/Aims: The diagnosis of tuberculous peritonitis, particularly in patients with chronic liver disease, is usually difficult since liver cirrhosis obscures the clinical features and alters the biochemical characteristics of ascites. The aim of th
이준성 ( June Sung Lee ) 대한간학회 2012 Postgraduate Courses (PG) Vol.2012 No.-
Ascites is of Greek derivation ("askos") and refers to a bag or sack. Although the diagnosis of ascties may be suspected on the basis of the history and physical examination, final confirmation is based on successful abdominal paracentesis or detection of ascites on imaging. Determination of the cause of ascites is based on the result of the history, physical examination, and ascitic fluid analysis. In general, few other tests are required. This article will highlight the various methods for differential diagnosis for ascites with an emphasis on how to differentiate the underlying cause of ascites.
장게실염에 병발한 간문맥과 장관막정맥 내 가스 및 혈전증
이준성(June Sung Lee),홍창권(Chang Kwon Hong),김경철(Kyung Chul Kim),홍성표(Sung Pyo Hong),황성규(Seong Gyu Hwang),박필원(Pil Won Park),임규성(Kyu Sung Rim),김종우(Jong Woo Kim),김희진(Hee Jin Kim) 대한소화기학회 2000 대한소화기학회지 Vol.36 No.3
The diagnosis of acute colonic diverticulitis and the assessment of its severity may be difficult. Especially, in the elderly patients with it, immediate diagnosis and initiation of therapy greatly influence the outcome. Pericolonic abscess and fistula formation, perforation, luminal obstruction, and peritonitis are well- known complications of diverticulitis. Rarely, the inflammatory process can extend into the venous drainage of the affected portion of the colon. Ultrasonography is a newly used imaging modality in patients under the suspicion of acute colonic diverticulitis and its complications. We experienced a case of colonic diverticulitis of which delayed diagnosis resulted in the development of portal and mesenteric vein gas and thrombosis. The literature on portal and mesenteric venous gas associated with colonic diverticulitis is reviewed, and the usefulness of ultrasound as a rapid, noninvasive tool to diagnose this rare condition is discussed. (Kor J Gastroenterol 2000;36:408 - 412)