전신조사방사선치료 시 Isodose Structure를 이용한 Field-in-Field Technique의 유용성 평가

이윤희,반태준,이우석,강태영,백금문,Lee, Yoon Hee,Ban, Tae Joon,Lee, Woo Seok,Kang, Tae Young,Back, Geum Mun 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 본원에서는 전신조사방사선치료 시 양 팔을 몸에 붙이고 누워있는 환자에게 좌우 양방향으로 방사선을 조사한다. 누운 자세는 기준점 두께에 대하여 신체 다른 부위와 두께 차이가 크기 때문에 보상체의 제작이 필요하고, 기준 깊이(Umbilicus) 처방선량에 대하여, 양팔(Arms)로 가려지지 않은 흉부와 복부 전면(Anterior)은 최대 20%까지의 선량차이가 나는 고 선량 영역이 된다. 이에 본 연구에서는 전신조사방사선치료 시 고 선량 영역과의 선량 차이를 줄일 수 있는 Isodose Structure를 이용한 Field-in-Field (FIF) Technique의 유용성을 평가 하고자 한다. 대상 및 방법: 인체모형등가팬텀(Rando Phantom, Alderson Resarch Laboratories Inc. Stamford. CT, USA, With Arm)으로 전산화단층촬영모의치료기의 영상을 획득하여 FIF와 납(Pb) 보상체를 이용한 전산화치료계획(Eclipse, version 10.0, Varian, USA)을 수립하였다. 두 치료계획의 흉부와 복부 부위의 선량분포를 비교하고, 수립된 치료계획을 이용하여 인체모형등가팬텀에 선량을 조사한 후, 열형광선량계(thermoluminescence dosimeter, TLD)와 필름(Film)을 이용하여 측정하였다. 결 과: 두 치료계획을 비교해 본 결과 기준깊이 처방선량에 대하여 팔로 가려지지 않은 흉부와 복부 전면의 선량차이는 FIF에서는 106~107%, 납 보상체를 이용한 치료계획에서는 114~124%였다. 열형광선량계를 분석한 결과로 FIF에서는 104~107%, 납 보상체를 이용한 치료계획에서는 110~117%의 기준깊이 처방선량과의 선량차이가 나왔다. 결 론: 본 실험에서 인체모형등가팬텀에 양 팔을 제작하여 치료 계획 및 선량을 조사해 보았다. 양 팔의 투과 유무에 따라 약 7~17%의 선량차이가 발생 하였다. 4단계의 FIF 기법으로 3차원 치료계획을 수립하여 전신에 약 95~107%의 균등한 선량 분포를 확인하였고 ${\pm}10%$ 이내의 선량 균일성을 유지 할 수 있을 것으로 분석 되었다. FIF 기법을 이용한 3차원 치료 계획은 환자 전신에 조사되는 선량을 미리 분석 할 수 있는 치료 계획으로 기존 치료 방법보다 균등한 선량의 전달이 가능할 것으로 사료된다. Purpose: In Asan Medical Center, Two parallel opposite beams are employed for total body irradiation. Patients are required to be in supine position where two arms are attached to mid axillary line. Normally, physical compensators are required to compensate the large dose difference for different parts of body due to the different thicknesses compared to the umbilicus separation. There was the maximum dose difference up to 30% in lung and chest wall compared to the prescription dose. In order to resolve the dose discrepancy occurring on different body regions, the feasibility of using Fieid-in-Field Technique is investigated in this study. Materials and Methods: CT scan was performed to The RANDO Phantom with fabricated two arms and sent to Eclipse treatment planning system (version 10.0, Varian, USA). Conventional plan with physical lead compensator and new plan using Field-in-Field Technique were established on TPS. AAA (Anisotropic Analytical Algorithm) dose calculation algorithm was employed for two parallel opposite beams attenuation. Results: The dose difference between two methods was compared with the prescription dose. The dose distribution of chest and anterior chest wall uncovered by patient arms was 114~124% for physical lead compensator while Field-in-Field Technique gave 106~107% of the dose distribution. In-vivo dosimetry result using TLD showed that the dose distribution to the same region was 110~117% for conventional physical compensator and 104~107% for Field-in-Field Technique. Conclusion: In this study, the feasibility of using FIF technique has been investigated with fabricated arms attached Rando phantom. The dose difference was up to 17% due to the attached arms. It is shown that the dose homogeneity is within ${\pm}10%$ with the CT based 3-dimensional 4 step FIF technique. The in-vivo dosimetry result using TLD was showed that 95~107% dose distribution compared to prescription dose. It is considered that CT based 3-dimensional Field-in-Field Technique for the total body irradiation gives much homogeneous dose distribution for different body parts than the conventional physical compensator method and might be useful to evaluate the dose on each part of patient body.

소아 요로감염의 진단

이윤희,김규찬,Lee, Yun-Hui,Kim, Gyu-Chan 대한소아감염학회 1995 Pediatric Infection and Vaccine Vol.2 No.1

흉막 삼출액을 동반한 전염성 단핵구증 1례

이윤희,노재호,박일성,정경식,김춘동,김창휘,Lee, Yoon Hee,Noh, Jae Ho,Park, Il Sung,Jeoung, Kyung Sik,Kim, Chun Dong,Kim, Chang Hwi 대한소아감염학회 2006 Pediatric Infection and Vaccine Vol.13 No.2

저자들은 임상적 소견과 검사실 소견에서 전염성 단핵구증으로 확진한 환아에게서 폐렴과 흉막 삼출액이 동반된 드문 1례를 경험하였다. 이에 문헌고찰과 함께 보고하는 바이다. Infectious mononucleosis(IM) is a clinical syndrome characterized by fever, exudative tonsillitis, gerneralized lymphadenopathy(90% of cases), splenomegaly(50% of cases), and hepatomegaly(10% of cases). It is mainly caused by Epstein-Barr virus(EBV) and usually recovered completely in the majority of cases. The complications of IM are splenic rupture, pancreatitis, hematologic problems such as hemolytic anemia, aplastic anemia, and thrombocytopenia, neurologic problems such as meningitis, encephalitis, and Guillian-Barr$\acute{e}$ syndrome, myocarditis, parotitis, orchitis, and interstitial pneumonitis, etc. Pulmonary involvement with EBV infection is rare condition reported frequency of 3% to 5%, in addition pleural effusion has been very rarely reported, especially in the pediatric population. We herein report a case of IM with pleural effusion in 3 years old boy with fever, cervical lymphnodes enlargement, and hepato-splenomegaly. And the pleural effusion is spontaneously resolved for a hospitalization period. A brief review of literature is included.

PWR 사용후핵연료의 Li 환원과정 모사 프로그램 개발

이윤희,신희성,장지운,김호동,윤지섭,Lee, Yun-Hee,Shin, Hee-Sung,Jang, Ji-Woon,Kim, Ho-Dong,Yoon, Ji-Sup 한국방사성폐기물학회 2006 방사성폐기물학회지 Vol.4 No.4

In this paper a computer program was developed, which simulates the Li reduction process of PWR spent fuel, and the amount of a produced metal or chloride compound was calculated at the various amount of Li with the program. It establishes a database, which is composed of some characteristics related to a chemical reaction equation and thermodynamic data, and it calculates the transformed rate of PWR spent fuel oxide at the certain amount of Li by using the database as input data. As the results of the performance test of the program, it was validated that the transformed values of oxides, except for $Eu_2O_3$ and $Sm_2O_3$, were almost the same to within about a 6 % error with those calculated by the previous code and that the calculated amount of Li was also exactly consistent with the theoretical one, which is used for a complete reaction of each oxide in a single chemical reaction. A relationship between Li and the transformed metal of each oxide was analyzed on the basis of the quantities calculated with the verified development program. Of the results, when the amount of Li was given to be 250 mole, the 83.73 percentage of $UO_2$ was transformed into U while the remainder was still to be $UO_2$. In addition, it was appeared that the 297 mole of Li was needed to completely convert $UO_2$ into U.

중의치험례(中醫治驗例)를 중심(中心)으로 살펴본 암성(癌性) 동통(疼痛)의 외치법(外治法)

이윤희,신민규,변준석,Lee, Yoon-Hee,Shin, Min-Kyu,Byun, Joon-Seok 대한암한의학회 2000 大韓癌韓醫學會誌 Vol.6 No.1

Carcinous pain is severe and continuous so difficult to alleviate. Western drugs give rise to reaction such as anorexia, constipation, vomiting, general weakness and dyspnea, And they cause tolerence. External treatment is a way to put a patch or rub a liquid on the skin. The patch and liquid are made from herb medicine. In china, they have a good effect of alleviating carcinous pain to make use of external treatment. Usually they use the medicine with effect of reprecussion (消腫), removing obstruction(散結), activating blood flow and removing blood stasis (活血化瘀) such like Borneloum(?片). Bufonis Venenum (蟾?), Aconiti ciliane Tubber(草烏), Arisaematis Rhizoma(南星), Asari herba cum Radice (細辛) etc. We can get the alleviating effect more quickly and prevent reaction through external treatment.

근대 건축물에 사용된 서양식 목조 지붕 트러스의 구조요인 및 기타 영향요인에 관한 연구 - 공공기관이 관리하는 문화재 중 근대건축물 기록을 중심으로 -

이윤희,유혜란,권기혁,Lee, Yoon-Hee,Yu, Hye-Ran,Kwon, Ki-Hyuk 한국건축역사학회 2011 건축역사연구 Vol.20 No.4

Western style timber roof trusses used as typical roof structures of buildings during a modern period have been developed with the interactions with their facade and functionality. The shapes of trusses and member sizes have been diversely changed by the purposes of architects, historical circumstances, and structural characteristics. For this reason, the change in the shapes of western style timber trusses along the times is one of important technology assets demonstrating the development of their structures during the modern period. Therefore, the purpose of this paper is to find out their structural characteristics throughout parametric analysis of which parameters were determined from the collected and classified documents on western style timber roof structure built in the modern period carefully obtained from public institutions. Results of the parametric analysis are as follows. The number of king-post trusses and modified king-post trusses built between 1920 and 1937 reaches almost half of the total number of truss types investigated. The mean values of their spans, distances, tributary areas, and height are respectively, 10.5m, 2.4m, $24.37m^2$and 3.24m. The cross-section areas of trusses tend to reduce since the city construction law was enacted in 1920. Also, this study found that western architects usually used larger structural members than eastern architects and usages and finishing materials of roof trusses are not always considered as one of the important design parameters.

임대주택(賃貸住宅)의 내재적(內在的) 특성(特性)에 관(關)한 연구(硏究) - 서울의 공동거주형(共同居住型) 임대주택(賃貸住宅)의 사례(事例)를 중심(中心)으로 -

이윤희,정재국,Lee, Yun-Hee,Jung, Jae-Kook 한국주거학회 2010 한국주거학회 논문집 Vol.21 No.4

In the modernization process of the city, urbanization raised a variety of social issues. Urbanization brought noticeable changes in dwelling patterns, such as drastic changes in the housing lifestyle, that revolved around the metropolitan areas of Seoul and Busan etc. before and after the expansion of economic growth. Especially in 1985, when 23.8% of the country's population was concentrated in Seoul, the imbalance of housing supply and demand caused a vast range of housing shortage. The shortage, that resulted from public sector mishandling of natural housing demand, lead to the occurrence of private sector rental housing. The occurrence of this abnormal rental housing supply, became a major cause of Korea's typical lease system called 'Co-dwelling', where the leaseholder and tenant physically lives in the same residence. The leaseholder and tenant's 'Co-dwelling' started from partial renting of traditional Korean-style housing and transformed with the transition of dwelling form and time. However, after 1985, legalization of multi-family housing, Korean rental housing started to be planned in the beginning of it's housing construction and to be produced as an independent space with separate circulation. Also in terms of facility, it changed from partial renting of a space within the residence to an assembly of small individual spaces. However, the background of this deep-rooted 'Co-dwelling' lease system, in different forms and periods of residence, is still based on the lack of public sector rental housing supply and private sector supply of rental space to utilize extra space, 'Jeonsei' payment.

변이계수에 대한 영향함수

이윤희,김홍기,Lee, Yun-Hee,Kim, Hong-Gie 한국통계학회 2008 Communications for statistical applications and me Vol.15 No.4

본 논문에서는 변이계수에 대한 영향함수를 유도한다. 경험적 영향함수와 표본영향함수를 이용하여 유도된 영향함수의 타당성을 입증하고 이를 위하여 정규분포 $N(20,1^2)$와 $N(20,5^2)$에서 각각 확률표본을 추출하여 시뮬레이션을 수행한다. 시뮬레이션 결과로부터, 유도된 변이계수에 대한 영향함수가 한 개의 관찰치가 제거되었을 때 변이계수의 변화량을 매우 정확히 추정하는 것을 확인하였다. We derive the influence function on the coefficient of variation. Empirical influence function and Sample influence function are used to verify the validity of the derived influence function. To show the validity of the influence function, we carry out simulations with random samples from normal distribution $N(20,1^2)$ and $N(20,5^2)$, respectively. The simulation result proves that the derived influence function is very accurate in estimating changes in the coefficient of variation when an observation is deleted.

교류자기장에 의한 유도가열체를 이용한 평판 디스플레이용 COG (Chip On Glass) 접속기술

이윤희,이광용,오태성,Lee Yoon-Hee,Lee Kwang-Yong,Oh Tae-Sung 한국마이크로전자및패키징학회 2005 마이크로전자 및 패키징학회지 Vol.12 No.4

교류자기장에 의한 유도가열체를 이용하여 LCD 평판 디스플레이 패널의 가열을 최소화하면서 IC 칩을 실장시킬 수 있는 COG 접속기술에 대해 연구하였다. 크기 5mm${\times}$5mm, 두께 $600{\mu}m$의 Cu 도금막으로 제조한 유도가열체에 14 kHz, 230 Oe의 교류자기장을 인가시 60초 이내에 유도가열체의 온도가 Sn-3.5Ag 무연솔더의 리플로우에 필요한 $250^{\circ}C$에 도달하였으며, 유도가열체로부터 2 mm 떨어진 부위에서부터 기판의 온도는 $100^{\circ}C$ 이하로 유지되었다. 이와 같은 Cu 도금막 유도가열체에 14 kHz, 230 Oe의 교류자기장을 120초 동안 인가하여 Sn-3.5Ag 솔더범프를 리플로우 시켜 COG 실장을 하는 것이 가능하였다. Chip-on-glass technology to attach IC chip directly on the glass substrate of flat panel display was studied by using induction heating body in AC magnetic field. With applying magnetic field of 230 Oe at 14 kHz, the temperature of an induction heating body made with Cu electrodeposited film of 5 mm${\times}$5 mm size and $600{\mu}m$ thickness reached to $250^{\circ}C$ within 60 seconds. However, the temperature of the glass substrate was maintained below $100^{\circ}C$ at a distance larger than 2 mm from the Cu induction heating body. COG bonding was successfully accomplished with reflow of Sn-3.5Ag solder bumps by applying magnetic field of 230 Oe at 14 kHz for 120 seconds to a Cu induction heating body of 5mm${\times}$5mm size and $600{\mu}m$ thickness.

나노 압입곡선의 이론적 분석을 통한 박막의 잔류응력 평가

이윤희,장재일,권동일,Lee, Yun-Hee,Jang, Jae-Il,Kwon, Dong-Il 대한기계학회 2002 大韓機械學會論文集A Vol.26 No.7

Residual stress is a dominant obstacle to efficient production and safe usage of device by deteriorating the mechanical strength and failure properties. Therefore, we proposed a new thin film stress-analyzing technique using a nanoindentation method. For this aim, the shape change in the indentation load-depth curve during the stress-relief in film was theoretically modeled. The change in indentation depth by load-controlled stress relaxation process was related to the increase or decrease in the applied load using the elastic flat punch theory. Finally, the residual stress in thin film was calculated from the changed applied load based on the equivalent stress interaction model. The evaluated stresses for diamond-like carbon films from this nanoindentation analysis were consistent with the results from the conventional curvature method.