애드 혹 네트워크에서 인접 행렬 기반의 라우팅 연구

이성수,김정미,박희주,김종근,Lee, Sung-Soo,Kim, Jeong-Mi,Park, Hee-Joo,Kim, Chong-Gun 한국정보처리학회 2008 정보처리학회논문지 C : 정보통신,정보보안 Vol.15 No.6

애드 혹 네트워크의 동적인 환경에서는 네트워크 토폴로지의 변화로 잦은 경로 단절과 이로 인한 전송 지연이 일어난다. 따라서 전송 지연에 민감한 애드 혹 네트워크의 실시간 환경에서는 효율적인 라우팅 방법이 주요 관심이 될 수밖에 없다. 그래프를 이용하는 통신 관련 이론의 주요 관심 중 하나는 주어진 노드들 중에서 어떠한 노드들이 연결되어 있으며, 최소 비용을 가진 경로는 어떻게 쉽게 찾을 것인가 하는 것 들이다. 애드 혹 네트워크에서 노드간의 연결은 인접 행렬로 나타낼 수 있다. 본 논문에서는 이러한 인접 행렬에 기반한 일련의 행렬 연산을 이용한 경로 검색 기법을 제안한다. 인접 행렬의 연산을 통해 구해진 연결 행렬을 이용하여 목적지로부터 소스까지 경로를 구하는 방법이다. 최단 경로를 검색하기 위한 인접 행렬 기반의 역검색 방법과 노드-비중첩 다중 경로를 검색하기 위한 인접 행렬 기반의 노드-비중첩 다중 경로 역검색 방법을 제안한다. With the dynamic and mobile nature of ad hoc networks, links may fail due to topology changes. So, a major challenge in ad hoc network is dynamically to search paths from a source to destination with an efficient routing method, which is an important issue for delay-sensitive real-time application. The main concerns of graph theory in communications are finding connectivity and searching paths using given nodes. A topology of the nodes in ad hoc networks can be modeled as an adjacency matrix. In this paper, based on this adjacency matrix, we propose new path search algorithms using a sequence of matrix calculation. The proposed algorithms can search paths from a destination to a source using connectivity matrix. Two matrix-based algorithms for two different purposes are proposed. Matrix-Based Backward Path Search(MBBS) algorithm is designed for shortest path discovery and Matrix-Based Backward Multipath Search(MBBMS) algorithm is for multipath search.

톨루엔 사용 근로자의 폭로량과 요중 마뇨산 배설량

이성수,안규동,이병국,남택승,Lee, Sung-Soo,Ahn, Kyu-Dong,Lee, Byong-Kook,Nam, Taik-Sung 대한예방의학회 1989 예방의학회지 Vol.22 No.4

The objective of this study was to examine the correlation between personal exposure of toluene at workplace and the concentration of hippuric acid in urine of male solvent workers. The study groups are 60 toluene exposed workers who worked at video tape factory and printing factory. The results are as follows : 1. The coefficient of correlation between toluene concentration of personal exposure and concentration of urinary hippuric acid was 0.649 (regression equation Y=0.015X+0.936, Y=urinary hippuric acid concentration, X=Toluene concentration of personal exposure). 2. Urinary hippuric acid concentration of workers with TLV 100 ppm of toluene was calculated 2.44 g/L by the regression equation (Y=0.015X+0.936).

영유아에서 담즙정체성 황달의 진단과 치료

이성수,Lee, Sung Soo 대한소아소화기영양학회 2008 Pediatric gastroenterology, hepatology & nutrition Vol.11 No.suppl2

Jaundice is common in breast-fed infants. Any infant noted to be jaundiced at 2 weeks of age need to be evaluated for cholestasis with measurement of total and direct serum bilirubin. The most common causes of cholestatic jaundice in infants are biliary atresia and neonatal hepatitis. Genetic causes of the neonatal hepatitis syndrome are increasingly recognized and idiopathic neonatal hepatitis is decreasing. Cholestasis should be investigated using a structured protocol. Early detection and timely, accurate diagnosis is important for successful treatment and a favorable prognosis. In particular, a Kasai portoenterostomy for biliary atresia has the best outcome if performed before the infant is 8 weeks of age. The management of cholestasis is mainly supportive, including nutritional support and alleviation of symptoms to improve the quality of life. Specific treatments are available for some causes of neonatal hepatitis syndrome and should be started as soon as possible. For decompensated liver disease, liver transplantation yields a better outcome.

양성 기관, 기관지 질환에서 확장성 금속 스텐트 사용에 관한 임상적 고찰

이성수,김도형,백효채,이두연,Lee Sung Soo,Kim Do Hyung,Paik Hyo Chae,Lee Doo Yun 대한기관식도과학회 2004 大韓氣管食道科學會誌 Vol.10 No.2

Background Insertion of tracheal stent in the treatment of benign tracheal & bronchial disease has increased since the introduction of expandable metallic stent. Material & Methods : Between Jan, 1995 and Feb. 2004, eight patients who had benign tracheo-bronchial disease underwent insertion of expandable metallic tracheal stent. We retrospectively analyzed stent insertion indications, complications, and following the result. Results : Surgical indications were post-intubation tracheal stenosis (1 case), tracheal stenosis following tracheal surgery (2 cases), tracheo-esophageal fistula (2 cases), broncho-pleural fistula(1 case), left main bronchus stenosis following bronchoplasty (1 case), and left main bronchus stenosis due to mediastinal repositioning (1 case). Expandable metallic tracheal stent was inserted in five patients to resolve dyspnea caused by airway obstruction, and to prevent recurrent pneumonia in three patients. The complication developed in 6 patients $75\%$; 3 cases of distal stenosis due to growth of granulation tissue, and one case each of tearing of posterior membrane, aggravation of tracheo-esophageal fistula, and airway partial obstruction due to stent migration. The stent was removed in 5 patients and tracheal surgery (tracheal resection and end to end anastomosis with primary repair of esophagus, pericardial patch tracheo-bronchoplasty, tracheal repair and omental wrapping) was performed in 3 patients. Conclusion Insertion of self expandable metallic stent in benign tracheo-bronchial disease is an effective means of relieving dyspnea for only a short period, and it did not increase the long term survival. Better means of treatment of benign tracheo-bronchial stenosis in necessary.

3세 이하 Mycoplasma pneumoniae 폐렴환자의 임상적 고찰

이성수,윤경림,강현호,조병수,차성호,Lee, Sung-Soo,Youn, Kyung-Lim,Kang, Hyeon-Ho,Cho, Byoung-Soo,Cha, Sung-Ho 대한소아감염학회 1999 Pediatric Infection and Vaccine Vol.6 No.1

Purpose : Mycoplasma pneumoniae pneumonia has been to be developed frequently in school age children and adolescence and hard to see under 3 year-old children. But it seems to be increased in number of patients with Mycoplasma pneumoniae pneumonia under 3-year old in clinical practice in these days. We have aimed to examine the characteristics of clinical findings of Mycoplasma pneumonia under 3 year-old children. Methods : We had performed retrospective review of medical records of 30 patients with Mycoplasmal pneumonia under 3-year old children who admitted to Department of Pediatrics, Kyunghee University Hospital from Jan. 1994 to Dec. 1997. The diagnostic criteriae was Cold agglutinin titer>1:64 or Mycoplasma antibody titer>1:80. Results : Mycoplasmal pneumonia was 30 out of 235 cases(12.7%) of total pneumonia under 3 year old children. Male female ratio was 1.3 : 1 and age distributions were 0~1y : 0, 1~2y : 8, 2~3y : 22 cases. Clinical symptoms and signs were cough(100.0%), sputum(83.3%), fever(80.0%) rhinorrhea(33.3%), vomiting(33.3%), moist rale(86.7%), decreased breathing sound(26.7%), wheezing(20.0%), and pharyngeal injection(30.0%). Thirteen out of 30 cases(43.3%) had unilateral infiltration, 10 cases(33.4%) had bilateral infiltration, 1 case(3.3%) had pleural effusion, and 6 cases(20.0%) had negative findings on chest radiography and there was no cases of atelectasis. On laboratory findings, 6 out of 30 cases(20.0%) had leukocytosis, 1 case(3.3%) had neutrophilia, 10 cases(30.0%) had eosinophilia, 17 cases(56.7%) had increased ESR, and 18 cases(60.6%) had positive CRP. Positive cold agglutinin titers(>1 : 64) were 19 cases(63.3%), and positive mycoplasma antibody(M-ab) titers(>1 : 80) were 27 cases(93.3%). Mycoplasma antibody test was more valuable than cold agglutinin test for the diagnosis of Mycoplasmal pneumonia and there was no correlation between cold agglutinin titer and mycoplasma antibody titer. Mycoplasma-polymerase chain reaction(M-PCR) was done with 13 cases, 12 out of 13 cases(92.3%) were positive. M-PCR test was valuable to the diagnosis of Mycoplasmal pneumonia but it will be needed to further study for their clinical application. Among 30 cases, 5 cases(16.7%) had complications, 3 cases(10.0%) had skin rash, 1 case(3.3%) had pleural effusion, 1 case(3.3%) had arthralgia, but all complications were mild and recovered without residual sequelae. Conclusion : The occurrence of Mycoplasmal pneumonia under 3 year-old children was not rare from this study. Clinical characteristics of Mycoplasmal pneumonia under 3-year old were normal radiologic findings in many cases, low complication rate, mild clinical course, and tend to rapid recovery compared with general manifestations of Mycoplasmal infectionsin children and adolescence. There were likely to be missed patients with Mycoplasmal pneumonia which did not diagnose by conventional serologic tests that had low sensitivity and specificity. We have to pay attention to the Mycoplasmal infection of the young children with pneumonia during epidemic periods of Mycoplasmal infection. 목 적 : 3세 이하에서 Mycoplasma pneumoniae 폐렴은 드문 것으로 알려져 있으나 최근 영유아에서도 Mycoplasma pneumoniae 폐렴이 많이 발생되고 있어서 3세 이하에서의 Mycoplasma pneumoniae 폐렴의 임상적 특성을 알아보고자 하였다. 방 법 : 1994년 1월부터 1997년 12월까지 4년간 경희대학교 부속병원 소아과에 입원한 환아 중 Mycoplasma pneumoniae 폐렴으로 진단된 3세 이하 환아 30명을 대상으로 의무기록 을 후향적으로 조사하여 임상양상, 혈청학적 소견, 방사선 소견, 합병증 및 치료 효과를 비교 분석 하였다. 결 과 : 1) 3세 이하에서 폐렴으로 입원한 환아 235명중 30명(12.7%)이 Mycoplasma pneumoniae 폐렴이었고 남녀비는 1.3 : 1로 남아에서 다소 높았다. 2) 발생시기는 여름 및 가을, 초겨울에 걸쳐 넓게 분포하였고 1994년과 1997년에 호발하였다. 3) 임상증상은 기침, 객담, 발열 순이었고, 그 외 콧물, 구토 증세도 나타났으며, 청진소견 상수포음이 26례(86.7%)로 가장 많았고, 그 외에 천명, 호흡음 감소가 나타났다. 4) 방사선 소견상 24례(80.0%)에서 폐침윤을 보였고, 일측성이 13례(43.3%), 양측성이 10 례(33.4%)였고, 흉막삼출이 있었던 경우는 1례(3.3%)였으며, 무기폐를 보인 경우는 없었고, 정상 소견이 6례(20.0%)였다. 6) 혈액검사당 백혈구 수는 정상인 경우가 24례(80.0%)였고, 호중구 증가를 보인 경우는 1례(3.3%)에 불과했으며, 호산구 증가는 10례(33.3%)에서 보였으며, 혈침속도 증가는 56.7%, CRP 양성률은 60.0%였다. 7) 냉응집소치가 양성인 경우는 19례(63.3%)였으며, Mycoplasma 항체치가 양성인 경우는 27례(90.0%)로 Mycoplasma 항체치가 더 높은 양성률을 보였으며 두 검사간 상관관계는 없었다. 또한 13례를 대상으로 시행한 Mycoplasma PCR 검사상 12례(92.3%)에서 양성반응을 보여 Mycoplasma pneumoniae 폐렴의 진단에 유용한 검사로 생각되나 이에 대한 임상적용 은 앞으로 더 연구되어야 할 것으로 사료된다. 8) 합병증으로는 피부발진 3례(10.0%)와 흉막삼출 1례(3.3%), 관절통 1례(3.3%)가 발생되었으나 경증이었고 후유증 없이 모두 완쾌되었다. 결 론 : Mycoplasma pneumoniae 폐렴은 3세 이하에서도 드물지 않게 발생되고 있으며, 임상양상의 특징으로는 방사선상 폐침윤이 없는 경우가 많고 합병증 발생이 적으며 증세가 경미하여 회복이 빠른 것 등이다. 3세 이하 폐렴 환아 중 진단되지 않고 누락된 환아가 다수 있을 것으로 생각되며 이 환아들을 포함하면 실제 발생률은 더 높을 것으로 사료된다.

정맥영양 관련 간기능 장애에서 조기 주기성 정맥영양법의 유용성

이성수,장주영,양혜란,고재성,최경희,서정기,Lee, Sung Soo,Chang, Ju Young,Yang, Hye Ran,Ko, Jae Sung,Choi, Kyung Hee,Seo, Jeong Kee 대한소아소화기영양학회 2004 Pediatric gastroenterology, hepatology & nutrition Vol.7 No.1

목 적: 담즙울체를 포함한 간기능 이상은 총정맥영양법을 시행받는 환자에게서 자주 나타나는 합병증 중 하나이며 이를 해소하기 위한 방법의 하나로서 주기성 정맥영양법이 있으나 소아에서는 이에 대한 연구가 미흡한 상태이다. 본 연구에서는 소아에서 총정맥영양법의 합병증으로 생긴 간기능 이상의 발생초기에 주기성 정맥영양법을 시행하여 그 유용성을 평가하고자 하였다. 방 법: 연구대상은 미숙아를 제외한 유소아로 총정맥영양법에 의한 담즙울체 및 간효소치의 증가를 보이고 혈역학적, 대사적으로 안정되었으며 주기성 정맥영양법이 간기능 이상을 보이는 초기에 시도되었던 12례의 환아들이었다. 주기성 정맥영양법의 중단시간은 3개월 미만에서는 2시간 이하, 그 이상에서는 4시간으로 하였다. 환아들의 의무기록지를 후향적으로 검토하였고 진단명, 지속성과 주기성 정맥영양법의 시행기간과 방법, 대사성 혹은 감염성 합병증 유무, 병행된 경관영양유무 및 정맥영양법을 시행하기 전후의 혈청 총 빌리루빈과 간효소치의 변화를 비교하였다. 결 과: 1) 환아들의 정중연령(median age)은 주기성 정맥영양법 시작시 4세(생후 2개월에서 17세)였고 기저질환은 만성가성장폐색증 4례를 비롯하여 다양하였다. 2) 동일 예에서는 대부분에서 투여된 단백과 포도당, 지방의 투여량에 차이가 없었다(p<0.05). 주기성 정맥영양법을 시행하는 동안 1례에서 잘 조절되지 않는 고혈당이 나타나 포도당의 감량이 필요하였으나 다른 대사성 및 정맥관의 감염과 관련된 합병증은 없었다. 3) 혈청 총빌리루빈은 총 5례에서 상승하였고 주기성 정맥영양법 시행 후 전 증례에서 정상화되었다(p<0.05). 주기성으로 전환시 혈청 빌리루빈은 3.6 mg/dL였으며 정상화된 때까지 걸린 기간은 8일이었다. 4) AST/ALT의 상승은 12례에서 모두 관찰되었고 주기성 정맥영양법 시행 후 전례에서 정상화되었다. 주기성으로 전환시 혈청 ALT는 200 IU/L였으며 주기성 정맥영양 시행 후 정상화된 때까지 걸린 기간은 34일이었다. 결 론: 저자들은 장기간의 총정맥영양법으로 인해 발생한 간기능 이상을 보인 유소아에서 주기성 정맥영양법으로의 조기전환이 효과적인 치료적 대안이 될 수 있으며 부작용이 적은 안전한 방법임을 관찰하였다. 향후 주기성 정맥영양법은 총정맥영양을 시행받는 소아들에서 간기능 이상을 방지하고 삶의 질을 높이기 위한 일차적인 방법으로 더욱 연구되어야 할 것으로 생각된다. Purpose: Liver function test abnormalities have been reported frequently in patients receiving total parenteral nutrition (TPN). In adults, it is known that liver complications decrease with the use of cyclic parenteral nutrition (CPN), especially if the shift to cycling was not too late. However, there are few studies about the effects of cycling on liver injury in children beyond the neonatal period. The aim of this study is to evaluate the effect of the early use of CPN on total parenteral nutrition induced hepatic dysfunction. Methods: Twelve sets of CPN in 11 children (2 months to 17 years) were included in this study. Data on underlying diseases, age, length of time on TPN, macronutrient intake, complications, and biochemical parameters were collected from clinical records. All children had received CPN in the early period of persistent transaminase elevation or cholestasis complicated by previous continuous PN. The duration of infusion off-time in CPN was 2 hours in patients less than 3 months of age and 4 hours in the older children. Results: All 12 cases showed elevated aminotransferase and 5 of them also showed cholestasis. Serum total bilirubin concentration was normalized in all 5 cases with median periods of 8 days (p<0.05) after initiation of CPN. ALT either decreased significantly or was normalized in all cases with median periods of 30 days (p<0.05) on CPN. The CPN was well tolerated without significant complication except for one case of hyperglycemia. Conclusion: The early use of cyclic parenteral nutrition had a beneficial effect in improving hepatic dysfunction complicated by TPN in children.

한우 종모우의 지방괴사증에 대한 Isoprothiolane 투여효과

이성수,임연수,정준,장윤호,박종관,박노형,원유석,김상근,Lee, Seoung-soo,Lim, Yeoun-su,Jeong, Joon,Jang, Yun-ho,Park, Jong-kwan,Park, No-hyoung,Won, You-seog,Kim, Sang-keun 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.3

The effect of isoprothiolane(di-isopropyl-1,3-dithiolan-2-ylidenemalonate) aganist fat necrosis in Hanwoo(Korean Cattle) sire was evaluated. The 10 heads of Hanwoo sire suffering from fat necrosis were given 50mg/kg body weight of isoprothiolane(0.2g/kg of Fujix, Japan) orally once a day for 8 weeks. In 30% of these, the size of the necrotic fat masses had decreased significantly 7 months after the adminstration. Isoprothiolane did not affect on live body weight and semen characteristics. However the sire affected with fat necrosis had higher MCHC(Mean corpuscular hemoglobin concentration) than normal sire in hematologic values 10 weeks after administration. Number of RBC(red blood cell) and PCV(packed cell volume) 10 weeks after administration had been increased than those before administration(p < 0.05). The serum concentrations of creatinine, triglyceride, and total cholesterol 10 weeks after administration were higher than those before administration while the concentration of glucose was vice versa. The isoprothiolane may reduce the oxidation of glucose, increase the glucose transfer to lipids, and increase blood supply to necrotic masses. These results indicate that isoprothiolane may be useful as the therapeutic agent aganist fat necrosis.

“근대불교 강맥(講脈)의 사자상승 연구 - 석전 박한영을 중심으로”

이성수 ( Lee Sung-soo ) 동국대학교 전자불전문화콘텐츠연구소 2023 전자불전 Vol.25 No.-

한국불교는 전통적으로 참선 수행을 중시해왔다. 근대에 들어서도 비슷한 양상이 이어졌지만, 근대학문을 수용하면서 교학을 확장 시켰다. 특히 20세기 전반 석전 박한영(石顚 朴漢永, 1870~1948)을 비롯해 진응혜찬(震應慧燦, 1873∼1941), 금봉병연(錦峰秉演, 1869~1916), 진호석연(震湖錫淵, 1880~1965), 퇴경상로(退耕相老, 1879~1965), 포광영수(包光映遂, 1884~1967) 등이 대강백으로 활약했다. 이들은 제자 가운데 교학에 밝고 후학을 양성할 만한 자격을 갖추었을 때 강맥(講脈)을 전했다. 석전 박한영은 “교육을 진흥시키는 자는 마땅히 불도(佛道)를 이루리라”며 인재 양성을 강조했다. 근현대 한국불교의 주요 강사를 배출한 박한영은 일제강점기 조선불교의 정체성을 수호하며, 독립운동가들과 교유한대표적인 선지식이다. 석전 박한영의 전강 제자는 운기성원(雲起性元, 1898~1982), 운허용하(耘虛龍夏, 1892~1980), 운성승희(雲惺昇熙, 1910~1995), 고봉태수(高峰泰秀, 1905~1968), 성능복문(性能福文), 철운종현(鐵雲宗玄, 1906∼1989), 명봉(明峯), 학봉 등이 있다. 이들 8명을 비롯해 손제자 26명, 증손제자 108명, 고손제자 23명 등 모두 165명이 석전 박한영의 강맥을 이었다. 이 가운데 상당수는 동국대 총장, 중앙승가대 교수, 해인사 승가대학장, 통도사 승가대학장, 동화사 승가대학장, 운문사 승가대학장, 봉녕사 승가대학장 등 종단의 주요 교육기관에서 후학을 양성했다. 또한 종정, 총무원장, 중앙종회의장, 총무원 집행부, 교구본사 주지 등 종단의 주요 소임을 본 사례도 상당수이다. 석전 박한영의 제자들은 교학 발전은 물론 근현대 한국불교에 큰 영향을 끼쳤다. Korean Buddhism has traditionally placed great importance on Ganhwaseon(看話禪). A similar pattern continued in modern times, but modern studies were accepted to expand teaching. In particular, Park Han-young, Jin Eung-hyechan, Geum Bong-yeon, Jin Ho Seok-yeon, Toekyung-ro, and Fogwang Young-soo took on the role of teachers. In the first half of the 20th century, they took on the role of teaching their disciples. And they passed on their Gangmaek (講脈) to those who were qualified to cultivate future generations. Park Han-young emphasized nurturing talent, saying, “Education is more important than anything else.” Park Han-young, who produced major scholars of modern and contemporary Korean Buddhism, is a representative monk who maintained the identity of Joseon Buddhism and communicated with independence activists during the Japanese colonial period. Park Han-young's disciples include Ungi Sung-won, Un Yong-ha, Unseong Seung-hee, Go Bong Tae-soo, Sung Neung Bok-mun, Cheol Un Jong-hyun, Myeongbong, and Hakbong. Park Han-young's students have been identified so far, with a total of 165. Among his disciples, he taught students at major educational institutions, including the president of Dongguk University, a professor at Chung-Ang University, the president of Haein Temple Sangha University, the president of Donghwa Temple Sangha University, the president of Donghwasa Sangha University, the president of Unmun Temple Sangha University, and the president of Bongnyeong Temple Sangha University. There are also many disciples who held important positions in the Jogye Order of Korean Buddhism. The disciples of Seokjeon Park Han-yeong had a great influence on the development of modern Korean Buddhism and Buddhist studies.

연폭로 남자 근로자들의 신기능 지표에 관한 연구

이성수,황보영,안규동,이병국,김정순,Lee, Sung-Soo,HwangBo, Young,Ahn, Kyu-Dong,Lee, Byung-Kook,Kim, Joung-Soon 대한예방의학회 1995 예방의학회지 Vol.28 No.2

The influence of lead exposure on renal function was studied. Eighty nine lead exposed workers who worked in 2 storage battery factories, and seventy one control workers were chosen for this study. Blood lead(PbB) and zinc protoporphyrin in whole blood(ZPP) were selected as indicators of lead exposure. As indicators of renal function, urinary N-acetyl-$\beta$-D-glucosaminidase(NAG), blood urea nitrogen(BUN), serum creatinine(S-Cr), total protein in urine(U-TP),and serum uric acid(S-Ua) were selected. The results obtained were as follows: 1. While the mean values of lead exposure indicators of lead workers were significantly different from non-exposed ones, the mean values of NAG, U-TP, BUN and S-Cr of renal function indicators of exposed were also significantly different from non-exposed but their mean values were all within normal limits. 2. BUN, logarithmic U-TP, logarithmic NAG and S-Cr showed statistically significant correlation with PbB. 3. The proportion of workers whose values of renal function indicators were over the normal limits(NAG7.5 U/g Cr ; U-TP10.9 mg/dl ; BUN20 mg/dl ; S-Crl.2 mg/dl ; S-Ua7.0 mg/dl) by the level of lead absorption in terms of PbB and ZPP were calculated. The proportion of workers with over the normal limits of U-TP among total workers showed the dose-response relationship. When age is adjusted, U-TP showed significantly strong dose-response relationship with the level of PbB and ZPP.

수정란 착상에 영향을 미치는 자궁내인자에 관한 연구

이성수,권종국,Lee, Sung-soo,Kwun, Jong-kuk 대한수의학회 1992 大韓獸醫學會誌 Vol.32 No.4

The present study was performed to identify the factors influencing on early pregnacy and embryo implantation in rabbit. Serum, uterine fluid, and uterine tissue were collected on day 0, 3, 5, 7 and 9 of pregnancy. The intrauterine environment of receptive phase and refractory phase was compared by measuring protein synthetic capacity of endometrium, amino acid composition and concentrations of lipids(phospholipid, cholesterol). The results obstained were as follows : 1. The concentrations of total protein were significantly increased (p<0.01) on day 5 ($7.00{\pm}0.55$), 7($6.29{\pm}0.65$), and 9($6.34{\pm}0.61$), compared to those on day 0($5.50{\pm}0.12g/100m{\ell}$) in serum. The concentration of albumin on day 0 was $0.81{\pm}0.05$ and reached maximum on day 5 ($1.59{\pm}0.07g/100m{\ell}$) in serum. The concentrations of total protein were significantly increased(p<0.01) on day 5($1.56{\pm}0.10$), 7($1.99{\pm}0.22$), compared to those on day 0($0.38{\pm}0.02g/100m{\ell}$) in uterine fluid. The concentration of albumin on day 5($0.78{\pm}0.05g/100m{\ell}$) was higher than those on the other days in uterine fluid. 2. The incorporation rates of [$^3H$]-leucine into protein were significantly increased(p<0.01) on day 5 ($919.6{\pm}97.5$), 7($1445.4{\pm}95.9$) and 9($450.38{\pm}28.71$), compared to those on day 0($328.2{\pm}38.9cpm/mg$ protein) in endometrium. The incorporation rates in colehicine-treated endometrium on day 5 ($1341.9{\pm}73.8$), 7($1729.4{\pm}63.3cpm/mg$ protein) were significantly higher(p<0.01) than those on the other days. 3. The compositions of amino acid were not distinctly changed during early pregnancy in serum. The composition ratios of methione, lysine were distinctly decreased on day 3, compared to those on day 0 in uterine fluid. Those of glycine, alanine were increased on day 9, compared to those on other days but his tidine decreased in uterine fluid. 4. The concentrations of total phospholipid and total cholesterol were significantly decreased(p<0.01) on day 3($77.9{\pm}15.5$, $61.5{\pm}21.2$), compared to those on day 0($164.0{\pm}33.9$, $167.2{\pm}46.2mg/100m{\ell}$)in serum. The concentrations of total phospholipid and total cholesterol on day 9 ($47.3{\pm}13.4$, $37.7{\pm}9.6mg/100m{\ell}$) were significantly higher(p<0.01) than those on the other days in uterine fluid. 5. Total phopholipid/total cholesterol ratios were not significantly changed during early pregnancy in serum. However, total phospholipid/total cholesterol ratios on day 5 ($2.00{\pm}0.42$), 7 ($1.11{\pm}0.77$) and 9 ($1.47{\pm}0.30$) were higher than those on day 3($0.84{\pm}0.41$) in uterine fluid. 6. The concentrations of phosphatidylcholine and phosphatidylserine were significantly increased (p<0.01) on the other days, compared to those on day 0 during early pregnancy in serum. The concentrations of phosphatidylcholine were significantly increased(p<0.01),compared to those on day 0 and those of phosphatidyl-ethanolamine were consistently increased but not significant in early pregnancy in uterine fluid.