http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이부길 ( Bu Ghil Lee ),정필문 ( Pil Moon Jung ),김현수 ( Hyun Soo Kim ),김익용 ( Ig Young Kim ),조미연 ( Mee Yon Cho ),이종국 ( Chong Kook Lee ),강태영 ( Tae Young Kang ) 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.4
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease of unknown cause, and is characterized by appearance of various autoantibodies and multiple organ involvement. Some of the systems commonly involved in SLE include the muscle and joints, brain and peripheral nervous system, lungs, heart, kidneys, skin, serous membranes, and component of blood. The clinical manifestations of SLE is protean, overlap with other illnesses, and are often subtle. However there are few documented reports on SLE associated with Crohn`s disease in other countries and no reporting case in Korea. We experienced a 30-year-old female patient who was admitted for right leg swelling and diagnosed as SLE with Crahn`s disease.
이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),노진규 ( Jin Kyu Noh ),이민수 ( Min Su Lee ),이남석 ( Nam Seok Lee ),이부길 ( Bu Ghil Lee ),리원연 ( Won Yeon Lee ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ),김상하 ( Sa 대한천식알레르기학회 2008 천식 및 알레르기 Vol.28 No.4
Occupational allergic rhinitis caused by rabbit fur has been reported in Korea. However, occupational asthma due to rabbit fur has not yet reported in Korea. We report a suspected case of allergic asthma caused by rabbit fur on occupational exposure. A 35-year-old male developed dyspnea, chest discomfort related to rabbit fur. He has been worked for a spinning factory. He presented with a history of allergic rhinitis and asthma. Peripheral blood eosinophil count was 690/mm3. Bronchodilator response was positive, the results of skin prick test were positive for house dust mite, cockroach and rabbit fur. The level of specific IgE for rabbit fur was 8.39 KU/L. The methacholine challenge test was positive (PC20 1.96 mg/mL). These findings suggest that the rabbit fur could induce occupational asthma. We could not perform bronchoprovacation test with rabbit fur due to patient`s refusal. He is in a well controlled state with the use of a combination of inhaled corticosteroid and long acting β2 agonist after the avoidance of rabbit fur. (Korean J Asthma Allergy Clin Immunol 2008;28:309-312)
김신태 ( Shin Tae Kim ),이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),정필문 ( Pil Moon Jung ),박홍준 ( Hong Jun Park ),신명상 ( Myung Sang Shin ),김종환 ( Chong Whan Kim ),이부길 ( Bu Ghil Lee ),김상하 ( Sang Ha Kim ),리원 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.6
Mycoplasma pneumoniae (M. pneumoniae) is the leading cause of pneumonia in older children and young adults. Normally, it does not progress to a condition requiring hospitalization but improves spontaneously or has a mild clinical course. We report two cases of M. pneumoniae pneumonia with different clinical manifestations from the normal course. The patients were young healthy individuals. The diagnoses were made by serology. However, it could not be determined beforehand that they had M. pneumoniae pneumonia. Based on the empirical treatment strategy of severe community acquired pneumonia, the patients were treated with broad-spectrum antibiotics including cephalosporin, quinolone and macrolide. After administering the antibiotics, they showed a gradually favorable clinical course and recovered without residual complications. A M. pneumoniae infection should be considered as a cause of severe community acquired pneumonia, and empirical treatment targeting this organism might be helpful in treating patients with the severe manifestation. (Tuberc Respir Dis 2007;63:515-520)
수술적 제거로 완치된 순수적혈구 무형성을 동반한 흉선종
김은미 ( Eun Mi Kim ),김상하 ( Sang Ha Kim ),권우철 ( Woo Cheol Kwon ),김호영 ( Ho Young Kim ),김종환 ( Chong Whan Kim ),이부길 ( Bu Ghil Lee ),정순희 ( Soon Hee Jung ),이종국 ( Chong Kook Lee ),용석중 ( Suk Joong Yong ) 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.5
Thymomas are associated with different paraneoplastic syndromes, with the most clinically important association being with myasthenia gravis, hypogammaglobulinemia, and pure red cell aplasia (PRCA). The optimal therapy for PRCA that complicates a thymoma is unknown, given the rarity of the clinical situation. It has been suggested that remission following surgery alone is uncommon and most patients will require some other form of therapy. We report a case of PRCA with a thymoma in a 59-year-old man who remained in complete remission of the PRCA after surgical resection of the thymoma. (Tuberc Respir Dis 2007;63:454-457)
흉수의 감별에 있어서 procalcitonin과 C-반응성단백의 유용성
김상하 ( Sang Ha Kim ),박주영 ( Joo Young Park ),박현숙 ( Hyun Sook Park ),서희석 ( Hee Seok Seo ),김신태 ( Shin Tae Kim ),김종환 ( Chong Whan Kim ),이부길 ( Bu Ghil Lee ),이석정 ( Seok Jeong Lee ),이선녕 ( Shun Nyung Lee ),노진규 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.4
연구 배경: 흉수의 감별을 위해 염증지표로 알려진 procalcitonin과 CRP를 흉수와 혈청에서 각각 측정하여, 삼출액과 여출액의 감별과 삼출성 흉수의 다양한 원인들에 대한 감별에 유용한지 확인하고자 하였다. 대상 및 방법: 2005년 10월 1일부터 2006년 9월 30일까지 흉수로 입원하였거나 입원 중에 흉수가 발생하였던 총 198명을 전향적으로 연구하였으며, 원인 질환으로 한 가지의 정확한 진단이 가능하였던 178명을 분석하였다. 악성 흉수 57명, 결핵성 흉수 51명, 부폐렴성 흉수 31명, 농흉 5명, 기타 원인의 양성 흉수 7명과 여출성 흉수 27명이었으며, 대상 환자의 혈청과 흉수에서 procalcitonin과 CRP를 포함한 측정값을 비교 분석하였다. 결과: 흉수 procalcitonin과 CRP는 여출액과 비교하여 삼출액에서 유의한 증가를 보였고, 흉수 CRP가 2.06 mg/dL 이상일 때 특이도 96.3%, 민감도 45.0%로 삼출액을 감별할 수 있었다. 악성 흉수와 비교하였을 때에도 흉수 procalcitonin과 CRP는 양성 흉수에서 유의한 증가를 보였고, 흉수 CRP가 2.28 mg/dL 이상일 때 특이도 86.0%, 민감도 53.2%로, 흉수 procalcitonin이 0.11 ng/mL 이상일 때 특이도 84.2%, 민감도 40.4%로 양성 흉수를 감별할 수 있었다. 또한 흉수 procalcitonin은 비결핵성 흉수에서 유의한 증가를 보였다. 결론: 흉수에서 CRP와 procalcitonin을 측정하는 것은 삼출액과 여출액의 감별뿐 아니라 삼출성 흉수의 다양한 원인들 감별 등에 보조적으로 사용하기에 유용하다. Background: Malignancies are a common and important causes of exudative pleural effusions. Several tumor markers have been studied because the pleural fluid cytology and pleural biopsy specimens do not provide a diagnosis in a high percentage of malignant effusions. In an attempt to overcome this limitation, procalcitonin and C-reactive protein (CRP) in pleural effusions and serum, which are known to be inflammation markers, were measured to determine if they can differentiate an exudate from trasndate as well as the diverse causes of exudative pleural effusion. Methods: 178 consecutive patients with pleural effusion (malignant 57, tuberculous 51, parapneumonic 31, empyema 5, miscellaneous benign 7, transudative 27)were studied prospectively. The standard parameters of pleural effusion and measured serum and pleural procalcitonin were examined using in immunoluminometric assay. The level of CRP in serum and pleural fluid was determined by turbidimetric immunoassay. Results: The pleural procalcitonin levels in the exudate were significantly higher than those in the transudate, 0.81±3.09 ng/mL and 0.12±0.12 ng/mL, respectively (p=0.007). The pleural CRP levels were significantly higher in the exudate than the transudate, 2.83±3.31 mg/dL and 0.74±0.67 mg/dL, respectively (p<0.001). The pleural procalcitonin levels in the benign effusion were significantly higher than those in the malignant effusion, 1.15±3.82 ng/mL and 0.25±0.92 ng/mL, respectively (p=0.032). The pleural CRP levels were significantly higher in the benign effusion than in the malignant effusion, 3.68±3.78 mg/dL and 1.42±1.54 mg/dL, respectively (p<0.001). The pleural procalcitonin levels in the non-tuberculous effusion were significantly higher than those in the tuberculous effusion, 1.16±3.75 ng/mL and 0.13±0.37 ng/mL, respectively (p=0.008). Conclusion: Measuring the level of procalcitonin and CRP in the pleural fluid is helpful for differentiating between transudates and exudates. In addition, it is useful for differentiating between benign and malignant pleural effusions. (Tuberc Respir Dis 2007; 63: 353-361)