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인간 치주인대 유래 섬유모세포에 대한 흡수성 교원질 차폐막의 생체적합성
권용대(Yong-Dae Kwon),이백수(Baeksoo Lee),주성숙(Sung-Sook Jue) 대한구강악안면외과학회 2006 대한구강악안면외과학회지 Vol.32 No.3
Purpose: This study is designed to evaluate biocompatibility of three types of absorbable collagen GBR membrane in vitro. Material and Method: The human PDL fibroblasts culture was obtained through typical way and the cells used in the experiment was forth passage. The membranes examined were Experimental group A, B, C. All the 3-experimental groups were made of bovine pericardium and the membranes were excised into 5×5mm respectively. The samples of the membranes were fixed on the 24-well plate with the double-sided adhesive tape. Then, 2ml of cell suspension which included 2×104cells was inoculated into the 24-well plate, and the cells were cultured for 1 week. Cellular viability and the alkaline phosphatase activity were measured with ELISA. The membranes in the culture were processed to examine with SEM. Results: The survival rate was highest in control and Experimental group A is the next, group B and group C in order of the value. The values are analyzed for statistical difference using Wilcoxon test. All the values of experimental groups are significantly lower than those of control, and the vaules among the experimental groups significantly differ from each other. Alkaline phosphatase level was identical order with the viable cell rate. SEM examination revealed that the PDL fibroblasts adherent on culture dish (control) and group A were spindle-shaped, but on group B and C, the cells were round-shaped without processes.
경구용 비스포스포네이트 관련 악골괴사의 합병증로 발생한 상악동염;
김영란,권용대(Yong-Dae Kwon),이백수(Baeksoo Lee),최병준(Byung-Joon Choi),Christian Walter,Bilal Al-Nawas 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.35 No.1
Maxillary sinusitis is an infectious disease which can arise from odontogenic etiology and a maxillary osteomyelitis can spread into the sinus and consequently develop maxillary sinusitis. In this case report, a mid eighty’s lady was diagnosed as BRONJ with maxillary sinusitis as a complication. The patient was managed successfully in collaboration with a endocrinologist. Through serial follow-up of serum CTX, we could decide the timing of surgical intervention