신속대응팀이 병동 환자의 심폐소생술 임상 결과에 미치는 영향

윤미정(Yoon, Mi-Jung),박진희(Park, Jin-Hee) 기본간호학회 2021 기본간호학회지 Vol.28 No.4

Purpose: This study investigated differences in the clinical outcomes of cardiopulmonary resuscitation (CPR) of patients hospitalized in general wards according to the operation of a rapid response team. Methods: This retrospective study included 122 patients over the age of 19 who were admitted to general ward of a hospital located in Suwon, between July 1, 2015 and December 31, 2019, and received CPR during the operating hours of the rapid response team. The collected data were analyzed by descriptive statistics, the x2 test, Fisher’s exact test, and one-way analysis of variance using SPSS for Windows version 25.0. Results: The proportion of nurses who were the initial responders to cardiac arrest was 79.1% during the extended-operation period. 41.2% during the pre-operation period, and 42.2% during the limited-operation period (p<.001). The rate of good neurological recovery at discharge post-CPR was 25.0% in patients who received CPR during the pre-operation period, 36.4% during the limited-operation period, and 87.5% during the extended-operation period (p=.042). Conclusion: This study identified clinical outcomes in patients who received CPR according to the operation status of the rapid response team. These results are expected to help in the further implementation of rapid response teams.

기업의 직원 교육 프로그램이 구성원의 직무역량에 미치는 영향에 관한 연구

윤미정(Mi-Jung Yoon),조인희(In-Hee Cho) 한국엔터테인먼트산업학회 2014 한국엔터테인먼트산업학회 학술대회 논문집 Vol.2014 No.5

현대의 우리나라 경제는 제2의 IMF를 걱정해야 하는 상황에 놓여 있다. 1999년 IMF 사태가 발생했을 때 그 위기를 기회로 삼아 돈을 더 많이 벌었다는 사람들도 있지만 대부분의 국민들은 하루하루를 불안한 마음을 가지고 살아야 했다. IMF사태를 극복하기 위해 가장 먼저 우리나라에서 생긴 일은 각 기업마다 구성원들을 정리하는 구조조정을 실시했다. "금 모으기 운동" 등 많은 시민들의 의지로 잘 극복이 되었지만 약 3년전부터 우리나라 경제는 한 해가 지날때마다 "내년에는 더 어려워진다"는 등의 보도가 나올만큼 불안한 상황 속에 놓여 있다. 그로 인해 각 기업에서는 조직 내 구조조정 및 명예퇴직을 권하고 있고, 사업계획에 있던 여러 프로그램 중 교육 사업에 대한 예산을 감소하면서 각 기업별 교육 시간이 줄어들고 사외강사는 점점 강의가 줄어들고 있는 상황이다. 교육 예산, 즉, 외부 강사료를 줄이는 대신 사내강사를 발굴하여 외부강사가 진행하던 교육을 사내강사가 진행하는 시스템으로 바뀌어가고 있다. 조직의 환경과 상황에 따라 기업에서는 교육에 대한 인식이 달라지고, 추진 계획이 변동이 있을 수 있겠으나 어려운 시기일수록 직원들의 역량개발을 위해 교육 사업에 예산을 더 투자한다면 그 구성원들이 발휘하는 역량으로 기업은 더 성장하게 될 것이다. Modern our country economy is situated in situation that must worry another IMF. When IMF situation happened in 1999 the crisis although there are people that three earned more money by an opportunity most peoples whole day with angst live must . Event that happen in our country firstest to cope IMF situation executed restructuring that retrench constituents in each company. Whenever "Exercise to gather gold" was overcomed well on many citizenses" artificial limbs and so on but year of our country economy passes from about 3nyeonjeon, it is situated in uneasy situation so much so that news of back announces that "Become more difficult on next year". Each company is persuading restructuring and voluntary resignation in formation thereby, and each company education time decreases estimate about educational work of several programs that is in plan of operation as decreasing and Saoegangsa is situation that fortitude is decreasing gradually. Instead of man speaker reduces education estimate, indeed, external speaker fare, is changing to system that it digs man speaker and progress education that external speaker progresses. Cognition about education changes in company according to formation"s environment and situation, and propulsion planning can be fluctuation but if invest more estimate in educational work for employees" capacity development it is difficult time, company is going to grow more by capacity that constituents display.

통합 미술교육프로그램의 효과에 관한 메타분석-유아의 창의성에 미치는 효과를 중심으로-

최미정 ( Choi Mi-jung ),정정희 ( Chung Chung-hee ),윤미승 ( Yoon Mi-seung ) 한국어린이문학교육학회 2017 어린이문학교육연구 Vol.18 No.1

본 연구는 통합 미술교육프로그램이 유아의 창의성에 미치는 효과를 메타분석하기 위한 목적으로 실시되었다. 이를 위해 2006년부터 2016년까지 발표된 일반대학원 석사 및 박사학위 논문, 학술지게재 논문 총 35편을 분석대상으로 하여 통합 미술교육프로그램이 유아의 창의성에 미치는 효과를 종합적으로 분석하고, 효과크기에 영향을 미치는 조절변인들을 검토하였다. 연구결과는 다음과 같다. 첫째, 통합 미술교육프로그램이 유아의 창의성에 미치는 전체 효과크기는 1.53으로 Cohen의 효과크기 기준으로 볼 때 매우 크다. 둘째, 통합 미술교육프로그램이 유아의 창의성에 미치는 효과크기는 프로그램 유형에 따라 유의한 차이가 나타났고, 연령, 집단구성 유형, 처치횟수에 따른 유의한 차이는 나타나지 않았다. 본 연구의 결과를 바탕으로 통합 미술활동의 효과성과 교육적 당위성을 뒷받침하는 근거가 제시되었으며 향후 미술교육이 나아가야 할 방향성을 제언하였다. The purpose of this study was to analyze the effect of early childhood integrated art education programs on the creativity of young children. A meta-analysis of related domestic Master`s and Doctor`s dissertations and journal papers from 2006 to 2016 was conducted, and 38 samples of effect size from 35 dissertations were collected for this study. The findings of this study are as follows. First, the overall effect size for integrated art education programs designed for improving the creativity of young children was 1.53, which confirmed that they produced large effects. Second, there was a significant difference in the effect size. The type of program in experimental groups proved to be the moderating variables which explain the difference in the effect size for the influence of the early childhood integrated art education programs on the creativity of young children. As a result, integrated art education programs are educationally significant in improving the creativity of young children.

한의학적 치료로 호전된 전이성 대장암 환자의 복통에 대한 증례보고

윤미정,김나연,최홍식,김승모,김경순,Yoon, Mi-jung,Kim, Na-yeon,Choi, Hong-sik,Kim, Seung-mo,Kim, Kyung-soon 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.4

Objectives: The aim of this case report is to present abdominal pain relief in a patient diagnosed with colorectal cancer with several organ metastases. Methods: The patient was treated with herbal medicine, acupuncture, and moxibustion. The effect of the treatment was measured by a numeric rating scale (NRS). Results: The NRS of the patient's abdominal pain was reduced after Korean medicine treatment. Conclusions: This case report suggests that Korean medicine may be effective for treating abdominal pain in cancer patients. However, additional study is needed to confirm interactions between Korean medicine and the control of abdominal pain.

수술실 간호사의 조직시민행동 영향요인

윤미정,임여진,Yoon, Mi Jung,Im, YeoJin 경희대학교 동서간호학연구소 2022 동서간호학연구지 Vol.28 No.2

Purpose: This study aimed to identify the factors related to the organizational citizenship behavior of nurses in the operating room (OR). These factors include positive psychological capital, perceived organizational culture, and job characteristics. Methods: A descriptive correlational study design was used. A total of 185 OR nurses from nine general and advanced general hospitals across three metropolitan areas in South Korea completed the questionnaires. The questionnaires included items on organizational citizenship behavior, positive psychological capital, organizational culture, and job characteristics. Descriptive statistics and multiple regression analysis were conducted using SPSS/WIN 21.0. Results: The mean score for organizational citizenship behavior was 3.62 out of 5. Positive psychological capital, relationship-oriented organizational culture, and feedback on job characteristics were verified as influencing factors of OR nurses' organizational citizenship behaviors. The explanatory power of this regression model was 48.2%. Conclusion: Reinforcement of positive psychological capital of individual OR nurses and organizational efforts to endorse relationship-oriented organizational culture is required. It follows that OR nurses' organizational citizenship behavior can be enhanced based on mutual trust, cohesiveness, and feedback on their work performance.

비소세포성 폐암의 척추 전이로 발생한 암성통증에 대한 초오 약침을 포함한 한방 치료 1례

윤미정,조나경,이유리,최홍식,김승모,김경순,Yoon, Mi-jung,Cho, Na-kyung,Lee, Yu-Ri,Choi, Hong-sic,Kim, Seung-Mo,Kim, Kyung-soon 대한암한의학회 2019 大韓癌韓醫學會誌 Vol.24 No.2

Objectives : The purpose of this case report is to examine clinical application of Traditional Korean medicine including aconitum ciliare decaisne pharmacopuncture for cancer pain caused by bone metastasis of non small cell lung cancer. Methods : The patient diagnosed as non small cell lung cancer was treated with pharmacopuncture, acupuncture, electroacupuncture and herbal medicine. We used NRS(Numeric rating scale) and ECOG PS(Eastern Cooperative Oncology Group Performance Status) to observe the effect of the treatment. Results : After the treatment, NRS of cancer pain and ECOG PS score decreased. Also, the frequency of using rapid-onset opioids decreased. Conclusions : This study suggests Traditional Korean medicine treatment including aconitum ciliare decaisne pharmacopuncture is effective in cancer pain control caused by metastasis to bone with multiple organs with non small cell lung cancer.

동씨침을 포함한 한방치료로 호전된 정계정맥류로 인한 통증 치험 1례

김나연,윤미정,최홍식,김승모,김경순,Kim, Na-yeon,Yoon, Mi-jung,Choi, Hong-sik,Kim, Seung-mo,Kim, Kyung-soon 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5

Objectives: This study investigated the effectiveness of Dong's acupuncture for pain associated with a varicocele. Methods: A 23-year-old male patient visited for pain due to varicocele that occurred on March 2 and was treated with acupuncture and moxibustion three times on March 16, 17, and 19. The Numerical Rating Scale (NRS) was used to evaluate the patient's pain. Results: After the three treatments, the NRS scores decreased, and the patient's subjective symptoms improved. Also, the patient required no medication for a week from the date of treatment start. Conclusions: These findings demonstrate that Korean medicine may be an option for treating a painful varicocele, but further research is required for confirmation.

Action Mechanism of Antiestrogens on Uterine Growth in Immature Rats

이중빈,윤미정,김창미,홍사석,유경자,Lee, Jung-Bin,Yoon, Mi-Chung,Kim, Chang-Mee,Hong, Sa-Suk,Ryu, Kyung-Za The Korean Society of Pharmacology 1990 대한약리학잡지 Vol.26 No.2

비스테로이드성 항에스트로젠제는 표적기관에서 estrogen 수용체와 상경적으로 결합하므로써 estrogen의 작용을 억제하는 것으로 알려져 있다. 비스테로이드성 항에스트로젠제는 대체로 triphenylethylene계로서 tamoxifen, clomiphene, LYl17018등이 있으며 표적기관에서 estrogen의 작용을 억제하기 때문에 estrogen과 관련된 질환을 치료하는데 이용되어 오고 있다. 본 연구에서는 생후 21-23일된 미성숙 흰쥐를 재료로 항에스트로젠제중 tamoxifen과 LY117018이 자궁세포 성장에 어떠한 영향을 미치며 어떠한 기전으로 estrogen의 작용을 길항하는지를 규명하고자, 항에스트로젠제가 estrogen작용의 중요 지포에 미치는 영향을 비교 관찰하여 다음과 같은 결과를 얻었다. Tamoxifen과 LY117018은 자궁세포에서 estrogen의 영향이 없는 경우에는 estrogen agonist로, estrogen작용하에서는 estrogen antagonist로서 작용하였다. Estrogen 작용의 여러 가지 지표에 대해 tamoxifen이 LY117018보다 agonistic effect는 더 컸으나, antagonistic effect는 LY117018이 더 큰 것으로 나타났다. Estrogen 수용체에 대한 결합능은 LY117018이 estradiol보다는 약간 낮았으나 용량에 비례하여 estrogen 수용체와 결합하였다. 그러나 tamoxifen은 estrogen 수용체에 대한 결합이 아주 낮았다. Estrogen 수용체에 대한 binding affinity는 estradiol(100%), LY117018(77%), tamoxifen(6.3%) 순으로 나타났다. 항에스트로젠제의 생체내 투여는 estrogen 존재 유무에 따라 estrogen 수용체 농도에 agonist 또는 antagonist로 작용하였다. 항에스트로젠제의 단독투여는 progesterone 수용체 생성을 증가시키나, estrogen에 의하여 유도된 progesterone 수용체 생성을 억제하였다. 이상의 결과로 보아, tamoxifen과 LY117018은 estrogen유무에 따라 흰쥐 자궁세포에서 estrogen antagonist로서 뿐만 아니라 agonist로서도 작용함을 알 수 있다. 그러나 estrogen수용체와의 결합능력이 아주 낮은 tamoxifen은, 용량에 비례하여 estrogen수용체에 결합하므로써 작용하는 LY117018과는 다른 기전으로 작용하는 것으로 생각된다. In the present study, we examined the effects of tamoxifen and LY117018 on various parameters for the estrogenic actions in order to understand the mechanism by which tamoxifen and LY117018 act on the uterine cells in 21-23 day old immature rats. Tamoxifen and LY117018 stimulated uterine weight and uterine contents of DNA, protein, and peroxidase activity in the absence of estradiol while inhibited above parameters in the presence of estradiol. Both cytosolic and nuclear progesterone receptors were increased by the treatment of tamoxifen and LY117018 as well as estradiol, but estradiol-induced increase in the progesterone receptors were reduced by the treatment of antiestrogens. These effects were enhanced by the multiple injections of antiestrogens. It seemed that tamoxifen was more agonistic than LY117018 but less antagonistic than LY117018, judged by their effects on various parameters for the estrogenic action. The affinities of estradiol, tamoxifen, and LY117018 for the estrogen receptor were $0.17{\pm}0.01nM(100%)$, $1.10{\pm}0.01nM(6.3%)$, and $0.23{\pm}0.01nM(77%)$, respectively. Furthermore, LY117018 was the competitive ligand for the estrogen receptor in dose-related manner but tamoxifen was not. Following estradiol treatment, nuclear estrogen receptor was sharply increased by 1 h, reaching the maximum by 16 h, while tamoxifen and LY117018 slightly increased nuclear estrogen receptor by 1 h and then decreased thereafter. It is therefore concluded that LY117018 is a competitive antagonist for the estrogen receptor with less estrogenic activity, compared to tamoxifen with low affinity to the estrogen receptor, and tamoxifen may act through other binding site than the estrogen receptor.

광, 온도, GA₃ 및 KNO₃ 처리가 산국 종자발아에 미치는 영향

백정애(Jung Ae Baik),강승원(Seung Won Kang),노아란(A Ran Rho),윤미정(Mi Jeong Yoon),박천호(Chun Ho Pak) 한국원예학회 2000 원예과학기술지 Vol.18 No.2

자궁세포 성장에 미치는 항에스트로젠제의 작용기전

이중빈(Jung Bin Lee),윤미정(Mi-chung Yoon),김창미(Chang-mee Kim),홍사석(Sa Suk Hong),유경자(Kyung-za Ryu) 대한약리학회 1990 대한약리학잡지 Vol.26 No.2

비스테로이드성 항에스트로젠제는 표적기관에서 estrogen 수용체와 상경적으로 결합하므로써 estrogen의 작용을 억제하는 것으로 알려져 있다. 비스테로이드성 항에스트로젠제는 대체로 triphenylethylene계로서 tamoxifen, clomiphene, LYl17018등이 있으며 표적기관에서 estrogen의 작용을 억제하기 때문에 estrogen과 관련된 질환을 치료하는데 이용되어 오고 있다. 본 연구에서는 생후 21-23일된 미성숙 흰쥐를 재료로 항에스트로젠제중 tamoxifen과 LY117018이 자궁세포 성장에 어떠한 영향을 미치며 어떠한 기전으로 estrogen의 작용을 길항하는지를 규명하고자, 항에스트로젠제가 estrogen작용의 중요 지포에 미치는 영향을 비교 관찰하여 다음과 같은 결과를 얻었다. Tamoxifen과 LY117018은 자궁세포에서 estrogen의 영향이 없는 경우에는 estrogen agonist로, estrogen작용하에서는 estrogen antagonist로서 작용하였다. Estrogen 작용의 여러 가지 지표에 대해 tamoxifen이 LY117018보다 agonistic effect는 더 컸으나, antagonistic effect는 LY117018이 더 큰 것으로 나타났다. Estrogen 수용체에 대한 결합능은 LY117018이 estradiol보다는 약간 낮았으나 용량에 비례하여 estrogen 수용체와 결합하였다. 그러나 tamoxifen은 estrogen 수용체에 대한 결합이 아주 낮았다. Estrogen 수용체에 대한 binding affinity는 estradiol(100%), LY117018(77%), tamoxifen(6.3%) 순으로 나타났다. 항에스트로젠제의 생체내 투여는 estrogen 존재 유무에 따라 estrogen 수용체 농도에 agonist 또는 antagonist로 작용하였다. 항에스트로젠제의 단독투여는 progesterone 수용체 생성을 증가시키나, estrogen에 의하여 유도된 progesterone 수용체 생성을 억제하였다. 이상의 결과로 보아, tamoxifen과 LY117018은 estrogen유무에 따라 흰쥐 자궁세포에서 estrogen antagonist로서 뿐만 아니라 agonist로서도 작용함을 알 수 있다. 그러나 estrogen수용체와의 결합능력이 아주 낮은 tamoxifen은, 용량에 비례하여 estrogen수용체에 결합하므로써 작용하는 LY117018과는 다른 기전으로 작용하는 것으로 생각된다. In the present study, we examined the effects of tamoxifen and LY117018 on various parameters for the estrogenic actions in order to understand the mechanism by which tamoxifen and LY117018 act on the uterine cells in 21-23 day old immature rats. Tamoxifen and LY117018 stimulated uterine weight and uterine contents of DNA, protein, and peroxidase activity in the absence of estradiol while inhibited above parameters in the presence of estradiol. Both cytosolic and nuclear progesterone receptors were increased by the treatment of tamoxifen and LY117018 as well as estradiol, but estradiol-induced increase in the progesterone receptors were reduced by the treatment of antiestrogens. These effects were enhanced by the multiple injections of antiestrogens. It seemed that tamoxifen was more agonistic than LY117018 but less antagonistic than LY117018, judged by their effects on various parameters for the estrogenic action. The affinities of estradiol, tamoxifen, and LY117018 for the estrogen receptor were 0.17 ± 0.01nM(100%), 1.10 ± 0.01nM(6.3%), and 0.23 ± 0.01nM(77%), respectively. Furthermore, LY117018 was the competitive ligand for the estrogen receptor in dose-related manner but tamoxifen was not. Following estradiol treatment, nuclear estrogen receptor was sharply increased by 1 h, reaching the maximum by 16 h, while tamoxifen and LY117018 slightly increased nuclear estrogen receptor by 1 h and then decreased thereafter. It is therefore concluded that LY117018 is a competitive antagonist for the estrogen receptor with less estrogenic activity, compared to tamoxifen with low affinity to the estrogen receptor, and tamoxifen may act through other binding site than the estrogen receptor.