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      • 기업의 직원 교육 프로그램이 구성원의 직무역량에 미치는 영향에 관한 연구

        윤미정(Mi-Jung Yoon),조인희(In-Hee Cho) 한국엔터테인먼트산업학회 2014 한국엔터테인먼트산업학회 학술대회 논문집 Vol.2014 No.5

        현대의 우리나라 경제는 제2의 IMF를 걱정해야 하는 상황에 놓여 있다. 1999년 IMF 사태가 발생했을 때 그 위기를 기회로 삼아 돈을 더 많이 벌었다는 사람들도 있지만 대부분의 국민들은 하루하루를 불안한 마음을 가지고 살아야 했다. IMF사태를 극복하기 위해 가장 먼저 우리나라에서 생긴 일은 각 기업마다 구성원들을 정리하는 구조조정을 실시했다. "금 모으기 운동" 등 많은 시민들의 의지로 잘 극복이 되었지만 약 3년전부터 우리나라 경제는 한 해가 지날때마다 "내년에는 더 어려워진다"는 등의 보도가 나올만큼 불안한 상황 속에 놓여 있다. 그로 인해 각 기업에서는 조직 내 구조조정 및 명예퇴직을 권하고 있고, 사업계획에 있던 여러 프로그램 중 교육 사업에 대한 예산을 감소하면서 각 기업별 교육 시간이 줄어들고 사외강사는 점점 강의가 줄어들고 있는 상황이다. 교육 예산, 즉, 외부 강사료를 줄이는 대신 사내강사를 발굴하여 외부강사가 진행하던 교육을 사내강사가 진행하는 시스템으로 바뀌어가고 있다. 조직의 환경과 상황에 따라 기업에서는 교육에 대한 인식이 달라지고, 추진 계획이 변동이 있을 수 있겠으나 어려운 시기일수록 직원들의 역량개발을 위해 교육 사업에 예산을 더 투자한다면 그 구성원들이 발휘하는 역량으로 기업은 더 성장하게 될 것이다. Modern our country economy is situated in situation that must worry another IMF. When IMF situation happened in 1999 the crisis although there are people that three earned more money by an opportunity most peoples whole day with angst live must . Event that happen in our country firstest to cope IMF situation executed restructuring that retrench constituents in each company. Whenever "Exercise to gather gold" was overcomed well on many citizenses" artificial limbs and so on but year of our country economy passes from about 3nyeonjeon, it is situated in uneasy situation so much so that news of back announces that "Become more difficult on next year". Each company is persuading restructuring and voluntary resignation in formation thereby, and each company education time decreases estimate about educational work of several programs that is in plan of operation as decreasing and Saoegangsa is situation that fortitude is decreasing gradually. Instead of man speaker reduces education estimate, indeed, external speaker fare, is changing to system that it digs man speaker and progress education that external speaker progresses. Cognition about education changes in company according to formation"s environment and situation, and propulsion planning can be fluctuation but if invest more estimate in educational work for employees" capacity development it is difficult time, company is going to grow more by capacity that constituents display.

      • SCOPUSKCI등재

        당근 ( Daucus carota L. ) 배양세포의 DNase 활성에 미치는 Polyamines 의 영향

        윤미정(Mi Chung Yoon),강영희(Young Hee Kang) 한국식물학회 1986 Journal of Plant Biology Vol.29 No.4

        The present study was attempted to investigate the effects of polyamines such as putrescine, spermidine and spermine on protein content and DNase activity in vivo and in vitro in carrot embryos. It was also investigated whether polyamines could replace role of cations required for DNase activity in vitro. The results obtained are as follows. Putrescine, spermidine and spermine increased protein content, although response to spermine reached plateau at the concentration of 0.1 mM. DNase activity was inhibited by polyamines, the inhibition being concentration-dependent and the highest at the concentration of 10 mM. The inhibition of DNase activity was the most prominent with spermine. Similar inhibitory effect of polyamines which was concentration-dependent was found in DNase activity but no change was shown on time-course in vitro. Putrescine and spermidine enhanced the DNase activity at low Mg^2+ and Mn^2+ concentrations, suggesting thet the role of Mg^2+ and Mn^2+ for DNase activity could be, in part, replaced by these polyamines. These results, therefore, suggest that polyamines can modulate DNase activity through binding to DNA rather than direct effect on DNase activity.

      • 흰쥐의 착상기간중 Estradiol이 자궁의 Phospholipase A<sub>2</sub> 활성도에 미치는 영향

        윤미정(Mi-chung Yoon),김창미(Chang-mee Kim),최임순(Rim-Soon Choe),유경자(Kyung-za Ryu) 대한약리학회 1991 대한약리학잡지 Vol.27 No.2

        본 연구에서는 흰쥐의 수정란 착상시기에 estradiol이 prostaglandins(PGs) 합성의 전구체인 arachidonic acid를 생성하는데 관여하는 phospholipase A<sub>2</sub>(PLA<sub>2</sub>)의 활성도를 조절하므로써 PGs의 합성을 촉진하는가를 조사하여 다음과 같은 결과를 얻었다. 자궁의 PLA<sub>2</sub> 활성도는 수정란이 착상하는 시기인 임신 제 5일에 증가되었으며, 비착상부위에서보다는 착상부위에서 더 높은 것으로 나타났다. Delayed implantation model에서, PLA<sub>2</sub> 활성도는 estradiol을 투여한 지 11시간후에 증가되었으며, dbcAMP를 투여한지 8시간후에 증가되었다. 또한 estradiol을 투여하기 2시간전에 phosphodiesterase inhibitor인 theophylline을 투여하면 estradiol만 투여한것에 비하여 PLA<sub>2</sub> 활성도가 증가되었다. Estradiol 또는 dbcAMP와 함께 indomethacin을 투여하면 자궁의 PGs합성은 억제되었으나 PLA<sub>2</sub> 활성도에는 영향을 주지않았다. 이상의 결과로 보아 흰쥐의 착상시기에 estradiol은 cAMP를 매개로하여 자궁의 PLA<sub>2</sub> 활성도를 촉진하므로써 PGs의 합성을 증가시키는 것으로 생각된다. The present study was performed to determine whether estradiol, via cAMP mediation, induces prostaglandin synthesis by modulating phospholipase A<sub>2</sub> activity which hydrolyzes phospholipids into arachidonic acids, a precursor for prostaglandin synthesis, during the implantation process in rats. Uterine phospholipase A<sub>2</sub> activity was elevated on day 5 of pregnancy when implantation normally occurs in rats. Moreover, phospholipase A<sub>2</sub> activity was higher in the implant sites than in the non-implant sites of uterus on day 6. In delayed implantation model, phospholipase A<sub>2</sub> activity was increased at 12 hrs after estradiol administration and at 8 hrs after dbcAMP administration. In addition, higher activity of phospholipase A<sub>2</sub> was induced by the treatment of estradiol plus theophylline, compared with estradiol-only treated group. The simultaneous treatment of indomethacin with estradiol or dbcAMP did not alter phospholipase A<sub>2</sub> activity compared with estradiol or dbcAMP-only treated group although significant suppression was observed in uterine PGE and PGE<sub>2α</sub> concentrations. These results suggest that estradiol or cAMP stimulates uterine phospholipase A<sub>2</sub> activity, thereby increasing prostaglandin synthesis during the implantation process in rats.

      • SCIESCOPUSKCI등재
      • KCI우수등재

        신속대응팀이 병동 환자의 심폐소생술 임상 결과에 미치는 영향

        윤미정(Yoon, Mi-Jung),박진희(Park, Jin-Hee) 기본간호학회 2021 기본간호학회지 Vol.28 No.4

        Purpose: This study investigated differences in the clinical outcomes of cardiopulmonary resuscitation (CPR) of patients hospitalized in general wards according to the operation of a rapid response team. Methods: This retrospective study included 122 patients over the age of 19 who were admitted to general ward of a hospital located in Suwon, between July 1, 2015 and December 31, 2019, and received CPR during the operating hours of the rapid response team. The collected data were analyzed by descriptive statistics, the x2 test, Fisher’s exact test, and one-way analysis of variance using SPSS for Windows version 25.0. Results: The proportion of nurses who were the initial responders to cardiac arrest was 79.1% during the extended-operation period. 41.2% during the pre-operation period, and 42.2% during the limited-operation period (p<.001). The rate of good neurological recovery at discharge post-CPR was 25.0% in patients who received CPR during the pre-operation period, 36.4% during the limited-operation period, and 87.5% during the extended-operation period (p=.042). Conclusion: This study identified clinical outcomes in patients who received CPR according to the operation status of the rapid response team. These results are expected to help in the further implementation of rapid response teams.

      • SCIESCOPUSKCI등재
      • KCI등재
      • KCI등재

        The Role of Angiogenesis in Obesity

        Michung Yoon(윤미정) 한국생명과학회 2014 생명과학회지 Vol.24 No.5

        혈관신생은 모든 조직의 성장과 발달, 그리고 상처회복 등에 매우 중요하다. 지방조직은 우리 몸에서 가장 혈관이 발달된 조직으로서 각 지방세포들은 모세혈관에 둘러싸여 있으며 신생혈관들은 지방세포에 영양분과 산소를 공급한다. 혈관의 내피세포들은 파라크린 신호경로, 세포외 성분, 세포들 간의 직접적인 작용을 통해 지방세포와 교류한다. 활성화된 지방세포들은 VEGF, FGF-2, leptin, HGF와 같은 혈관신생인자들을 생성하며, 이들은 단독으로 혹은 협력하여 혈관신생을 증가시키고 지방조직의 성장과 대사를 촉진한다. 따라서 혈관신생 억제제들은 비만과 비만관련 질환을 치료하는데 유용할 것으로 생각된다. Angiogenesis, the formation of new capillary blood vessels, is a tightly regulated process. Under normal physiological conditions, angiogenesis only takes place during embryonic development, wound healing, and female menstruation. Dysregulation of angiogenesis is associated with many diseases, such as cancer, rheumatoid arthritis, psoriasis, and proliferative retinopathy. The growth and expansion of adipose tissue require the formation of new blood vessels. Adipose tissue is probably the most highly vascularized tissue in the body, as each adipocyte is surrounded by capillaries, and the angiogenic vessels supply nutrients and oxygen to adipocytes. Accumulating evidence shows that capillary endothelial cells communicate with adipocytes via paracrine signaling pathways, extracellular components, and direct cell-cell interactions. Activated adipocytes produce multiple angiogenic factors, including VEGF, FGF-2, leptin, and HGF, which either alone or cooperatively stimulate the expansion and metabolism of adipose tissue by increasing adipose tissue vasculature. Recently, it was demonstrated that antiangiogenic herbal Ob-X extracts and Korean red ginseng extracts reduce adipose tissue mass and suppress obesity by inhibiting angiogenesis in obese mice. Thus, angiogenesis inhibitors provide a promising therapeutic approach for controlling human obesity and related disorders.

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