미니돼지에서 Acellular dermal matrix에 배양된 치주인대섬유모세포을 이용한 자가치아이식술: 치주인대로써의 잠재력에 대한 조직학적 평가

유상준,김병욱,박주철,장현선,Yu, Sang-Joun,Kim, Byung-Ock,Park, Joo-Cheol,Jang, Hyun-Seon 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.1

The aim of this study was to examine the possibility of periodontal ligament regeneration when autotransplantation was used by the periodontal ligament fibroblasts cultured on the acellular dermal matrix in teeth without a periodontal ligament. One minipig was used in this study. The mandibular and maxillary permanent incisors were ex-tracted for the culture of the periodontal ligament cells. The roots of the unextracted teeth were classified into a positive control group, in which the normal periodontal ligament was preserved. The roots of the extracted teeth were divided into the following two groups: The negative control group, in which the periodontal ligament had been removed and the acellular dermal matrix was not applied; and an experimental group, in which the periodontal ligament had been removed and periodontal ligament fibroblast cultured on an acellular dermal matrix was applied. The prepared teeth were transplanted, and completely submerged using physical barrier membranes. The animal was sacrificed 4 weeks after the autotransplant. The transplanted teeth were examined histologically. In this study, the periodontal ligament was normal in the positive control group, and ankylosis was discovered on the denuded root surface in the negative control group. Periodontal ligament-like connective tissue was found adjacent to the denuded root and the new cementum-like layer of hard tissue was formed in the experimental group. These results suggest that the periodontal ligament fibroblasts cultured on the acellular dermal matrix may play a role in regenerating the periodontal ligament-like tissue with new cememtum-like tissue formation.

임플란트식립을 위한 치조제증대술

유상준(Sang-Joun Yu) 대한치과의사협회 2019 대한치과의사협회지 Vol.57 No.12

Alveolar bone resorption are unpredictable and always occur after tooth extraction. Such bone resorption causes insufficient alveolar ridge which make implant placement difficult. There are many techniques to increase the alveolar ridge. Representative procedures include ridge split, guided bone regeneration, bone graft using autogenous block bone, and alveolar distraction. In each procedure, there are indications and complications. Depending on the shape and the width of bone defects, we can choose procedures for horizontal bone augmentation and vertical bone augmentation.

임플란트 주위 치간유두의 보존 및 재건술

정민구 ( Min Gu Jung ),유상준 ( Sang Joun Yu ) 조선대학교 구강생물학연구소 2012 Oral Biology Research (Oral Biol Res) Vol.36 No.1

Currently, with increased esthetic demands, implantologists must establish a harmonious gingival contour and an intact papilla. Height and contour of peri-implant papilla are infl uenced by a position of the implant, an osseous support, a volume of gingival embrasure, and a biotype of interdental gingiva. Various hard and soft tissue surgical techniques for preservation and reconstruction of papilla have been introduced. Preservation and reconstruction of alveolar bone under an area of interdental papilla is the foundation for the presence of papilla by socket preservation, guided bone regeneration. Soft tissue grafting can be used to enhance esthetic outcomes. For preservation and reconstruction of peri-implant papilla, a multidisciplinary approach involving both the restorative dentist and surgeon should be followed.

치과 임플란트 주위질환의 진단 및 분류: 문헌고찰

이화선 ( Hwa Sun Lee ),유상준 ( Sang Joun Yu ),김영준 ( Young Joon Kim ),김병옥 ( Byung Ock Kim ) 조선대학교 구강생물학연구소 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.1

This review study was performed to summarize previous studies concerning biologic findings of implants compared to natural teeth, diagnostic tools, and classifications of peri-implant disease. Peri-implant tissue has been proven to have a different biologic attachment system, which causes a weaker barrier to plaque or bacterial infection. Further, formation of biologic width following engagement of the transmucosal part of the implant should be considered before surgery, and clinicians should invest stable tissue conditions around the implant. Although various risk factors are involved in peri-implant disease, plaque deposition, history of periodontitis, and smoking showed strong evidence of disease. Peri-implant disease can be diagnosed by probing with proper pressure (0.25 N), and bleeding on probing is highly related to peri-implantitis. Further, radiographic examination such as intaoral x-ray, panoramic view, and cone-beam computed tomography can help to diagnose disease and classify the state of peri-implantitis. The classification of peri-implantitis can be diverse. Until now, three-stage classification by Froum & Rosen (early, moderate, and advanced), diagnosed by probing depth, bleeding upon probing, and percentage of remaining bone, is useful as a clinical approach.

상피하 결합조직 이식술을 이용한 치근피개술: 증례보고

이민재 ( Min Jae Lee ),이상준 ( Sang Jun Lee ),이창규 ( Chang Kyu Lee ),김병옥 ( Byung Ock Kim ),유상준 ( Sang Joun Yu ) 조선대학교 구강생물학연구소 2011 Oral Biology Research (Oral Biol Res) Vol.35 No.2

Surgical procedures used in the treatment of recession defects have been introduced. These procedures can be devided into pedicle soft tissue graft procedures and free soft tissue graft procedures. The former procedures include advanced procedures which consist of coronally advanced flap and rotational flap procedure. The latter procedures include epithelialized graft and subepithelial connective tissue graft. The purpose of this case report is to introduce the short term outcome of subepithelial connective tissue graft for root coverage. Treatments for root coverage were performed for 3 patients who visited the department of periodontics in Dental Hospital of Chosun University with gingival recession as chief complain with or without hypersensitivity. These patients belonged to Miller class I. Advanced flap procedures were performed and subepithelial connective tissue graft was done for 3 patients. Pre and post operative clinical evaluations were performed to patients. All patients treated showed complete root coverages and there was no other complications. Advanced flap procedures and subepithelial connective tissue graft may be options in treatment for Miller class I gingival recession.

교습 간격 및 방법이 치면세균막 관리능력 향상에 끼치는 영향

박도영 ( Do Young Park ),이병진 ( Byoung Jin Lee ),김병옥 ( Byung Ock Kim ),유상준 ( Sang Joun Yu ) 대한예방치과·구강보건학회 2015 大韓口腔保健學會誌 Vol.39 No.2

Objectives: This study aimed to evaluate the effect of oral health education interval and toothbrushing instruction, the difference between the demonstration-only method and the demonstration with chairside practice toothbrushing instruction method, and the effect of initial patient plaque control ability on the plaque index. Methods: Patients (n=60) were randomly assigned to receive a 1-week, 2-week, or 3-week interval of oral health education and toothbrushing instruction. Each group was further subdivided into the demonstration-only group and the demonstration with chairside practice group. Patients were categorized as having “good”, “fair”, or “poor” initial plaque control ability, based on the Turesky modification of the Quigley-Hein plaque index (TQHI). Patients attended five sessions during which they received oral health education and toothbrushing instruction of the modified Bass technique. Plaque evaluation was performed at each visit using the TQHI. Results: The plaque index tended to improve from the first visit to the fifth visit, but there were no significant differences between the 1-week, 2-week, and 3-week education interval. The demonstration with the chairside practice group showed significantly greater improvements in the plaque index, compared to the demonstration-only group. In the good, fair, and poor plaque control ability groups, the plaque index improved gradually from the first to the fifth visit. When plaque control was poor, the improvement in the plaque index increased to a greater degree after oral health education and toothbrushing instruction. Conclusions: The results of this study may be helpful for suggesting appropriate individualized oral hygiene management methods to improve plaque control ability.

변형된 의도적 재식술을 통한 병적 이동된 치아들의 치료

김현수(Hyun-Soo Kim),이원표(Won-Pyo Lee),유상준(Sang-Joun Yu),김병옥(Byung-Ock Kim) 대한치과의사협회 2016 대한치과의사협회지 Vol.54 No.8

Pathologic tooth migration (PTM) caused by periodontal disease is a relatively common disease with a prevalance rate of 30~55%. It is one of the reasons for periodontal treatment of patients. PTM occurs when various factors related to the position of the tooth are altered and clinical features of PTM include facial flaring, diastema, proximal tilting, rotation, and extrusion of teeth. The purpose of this study was to assess the treatment of teeth of hopeless prognosis through the practice of modified intentional replantation on pathologic migrated tooth. This study presents cases using modified intentional replantation for the treatment of pathologic tooth migration caused by severe periodontitis. Modified intentional replantation is a technique that prepares extraction socket by using an implant drill. Based on 3 cases performed with modified intentional replantation, an improvement of clinical periodontal indicators such as probing pocket depth, bleeding on probing, tooth mobility, and pathologic teeth migration was observed after surgery. Also, the patients were satisfied with the functional and esthetic improvement.

위축된 하악 구치부 치조정에 치조제 분리술을 이용한 임플란트 동시식립: 증례보고

박도영 ( Do Young Park ),한정균 ( Jeong Gyun Han ),유상준 ( Sang Joun Yu ),김병옥 ( Byung Ock Kim ) 조선대학교 구강생물학연구소 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.2

When the width of the alveolar ridge is insufficient, bone augmentation procedures are routinely performed before dental implant placement. Several techniques for this procedure, such as guided bone regeneration, block bone grafting, and ridge-splitting for bone expansion, can be performed. Lateral augmentation is a traditional grafting procedure that uses particulate materials, solid block bones, autogenous bone, allografts, xenografts, or barriar membranes. However, this method is characterized by increased costs, membrane exposure, a second surgical site, failed fusion of the graft bone to the basal bone, and an extended healing period. On the other hand, segmental ridge-split technique constitutes a quicker method wherein an atrophic ridge can be predictably expanded, thereby eliminating the need for a second surgical site. Simultaneously, dental implants are placed within the split ridge. This article presents cases in which ridge-split technique is applied with simultaneous implant placement when the width of the mandible is insufficient.

치아재식술을 통한 치주 조직 재생의 가능성 문헌고찰

박도영 ( Do Young Park ),김병옥 ( Byung Ock Kim ),유상준 ( Sang Joun Yu ) 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.2

Periodontitis is caused primarily by dental plaque microorganism. Periodontitis is characterized by the destruction of the periodontium. Sometimes for the patients with severe periodontal diseases who have advanced bone destruction, both surgical and non-surgical methods may not be successful. In these cases, intentional replantation may be an alternative choice at least for a period of time. The following applications are needed for successful periodontal regeneration of replanted teeth. First of all, mechanical, environmental, inflammatory trauma need to be minimized to protect the periodontal tissue on the root surface and alveolar bone surface in the extraction socket. Second, root surface treatment is needed to remove infected tissue and conserve as much cementum as possible. Third, growth factors can be applied to promote the regeneration of periodontal tissue. Fourth, various cell-based approaches can be applied for periodontal tissue regeneration in severe compromised periodontal defect.

임플란트 2차 수술 시 porcine collagen matrix 이식을동반한 근단변위판막술의 임상적 평가 증례보고

신희종 ( Hee Jong Shin ),이원표 ( Won Pyo Lee ),정명진 ( Ming Zhen Zheng ),송현종 ( Hyun Jong Song ),유상준 ( Sang Joun Yu ),김병옥 ( Byung Ock Kim ) 조선대학교 치의학연구원 2014 Oral Biology Research (Oral Biol Res) Vol.38 No.1

The significance of keratinized mucosa in implant maintenance is a controversial issue. As such, there is no consensus regarding the relationship between the width of keratinized mucosa and the health of peri-implant tissue. However, clinicians prefer to provide enough keratinized mucosa around implants for long-term implant maintenance and stabilization of the gingival margin position. The purpose of this case report is the clinical evaluation of an apically positioned flap with a porcine collagen matrix to provide keratinized mucosa and deepen the vestibule around implants during second stage implant surgery. In this case report, a clinically relevant amount of keratinized mucosa was achieved around implants and the vestibule was deepened. Thus, an apically positioned flap with a porcine collagen matrix is an available technique for providing keratinized mucosa and deepening the vestibule around implants during second stage implant surgery. This technique could be potentially used in routine autogenous or another graft procedures to provide keratinized mucosa around implants.