일측성 성대마비 환자에서 Artecoll을 이용한 성대주입술의 효과 및 안전성

오재원,이승원,김민범,윤영선,김관민,손영익,Oh Jae-Won,Lee Seung-Won,Kim Min-Beom,Yun Young-Sun,Kim Kwan-Min,Son Young-Ik 대한후두음성언어의학회 2005 대한후두음성언어의학회지 Vol.16 No.2

Background and Objectives : Artecoll(R) is an injectable soft tissue filler, which is a suspension of polymethylmethacrylate microspheres in $3.5\%$ bovine collagen solution. The authors aimed to determine the clinical of Artecoll of Artecoll(R) as an injection material into the vocal fold to correct the glottal insufficiency caused by unilateral vocal cord paralysis. Materials and Methods : Forty-one consecutive patients with unilateral vocal cord paralysis received percutaneous Artecoll injections under local anesthesia. Acoustic, aerodynamic and stroboscopic analyses were prospectively provided before, 1 week and 3 months after injection. Perceptual GRBAS grading by speech language pathologists and subjective ratings of the hoarseness and aspiration by the patients were also obtained. Results : Aerodynamic parameter(maximal phonation time) were significantly improved after the injection (p<0.05). Acoustic parameters (jitter and shimmer) were improved at the 3rd month follow-up. GRBAS uading and patients own subjective scaling of hoarseness and aspiration also showed significant improvement (p<0.05). Early or delayed significant side effects were not observed. Conclusion : Vocal fold injection with Artecoll is a convenient, safe and useful method of temporarily correcting the glottal insufficiency. Further long-term follow-up studies will answer the usefulness and safety of the Artecoll injection laryngoplasty.

소프트웨어 패키지 평가를 위한 평가집합의 생성 및 유지를 위한 메타 모델

오재원,이종원,박동철,이병정,우치수,김순용,송기평,Oh, Jae-Won,Lee, Chong-Won,Park, Dong-Chul,Lee, Byung-Jeong,Wu, Chi-Su,Kim, Soon-Yong,Song, Gi-Pyeung 한국정보처리학회 2004 정보처리학회논문지D Vol.11 No.3

오늘날 소프트웨어 산업의 발전은 소프트웨어 패키지 제품들의 양적 팽창을 이루게 하고 있다. 이러한 급속한 소프트웨어 패키지 제품의 증가 추세에 따라서, 사용자가 선택하는 소프트웨어 제품에 대한 품질 인증 요구가 대두되었다. 공산품의 품질 인증과는 달리, 소프트웨어 제품의 경우 아직 인증 역사가 길지 않고 이를 위한 소프트웨어 품질 평가 및 인증 방법 연구는 성숙되지 않았다. 소프트웨어 제품 인증 업무 시 중요한 요소 중의 하나가 평가 집합의 체계적인 생성이다. 평가 집합이란 소프트웨어 제품 유형의 분류에 따라서 소프트웨어 품질 인증을 위한 기준과 메트릭을 명시한 체크리스트를 포함한다. 본 논문에서는 평가 집합의 체계적 생성 및 유지 관리를 위한 베타 모델을 제안한다. 그리고 메타 모델의 유효성을 확인하기 위하여 프로토타입 수준의 평가 집합을 생성한다 Today, the growth of software industry leads to e quantitative expansion of software package products. Due to this rapid increase of software package products, qualify certification has been required fur software products which users select. Unlike the quality certification of industrial products, the history of software product certification has not been so long. For this reason, software quality evaluation and certification methods have not matured yet. When certifying software products, one of most important factors is the systematic generation of evaluation sets. The evaluation sets include checklists with metrics, and criteria for the software quality certification according to the classification of software product type. This paper presents a metamodel for the systematic generation and maintenance of the evaluation sets. Then, we construct prototype level evaluation sets to show the validity of the metamodel.

TRIZ를 활용한 설계VE의 효율적 추진방안

오재원,김광수,Oh, Jae-Won,Kim, Kwang-Soo 한국벤처창업학회 2012 벤처창업연구 Vol.7 No.1

설계VE를 수행함에 있어서 아이디어 발상 단계의 한계사항을 지적하고, TRIZ와 적절한 연계를 통하여 보다 효과적인 방안을 모색하고자 한다. 창의적이고 체계적인 접근과 효율적인 아이디어 발상을 통하여, 보다 최적에 가까운 대안을 도출할 수 있는 설계VE/TRIZ 의 추진절차와 단계별 업무내용을 제시하였다. Design VE is a kind of contradictive administrating that pursue both value improvement and cost reduction, whereas TRIZ is a method used to solve contradiction based on its invention principal. This paper comprehended the problems regarding the object through design VE using function analysis, and presented a number of methods to solve this by using the principal of TRIZ. This study compared the characteristics of Design VE and TRIZ, and suggested a procedure that integrates both Design VE and TRIZ.

ABS 열분해로부터 유용성분 회수를 위한 금속산화물의 효과

오재원,김기홍,김희택,류경옥 ( Jae Won Oh,Ki Hong Kim,Hee Taek Kim,Kyong Ok Yoo ) 한국화학공학회 1995 화학공학의이론과응용 Vol.1 No.2

MEE법으로 성장한 InAs/GaAs 양자점의 발광특성

오재원,변혜령,류미이,송진동,Oh, Jae Won,Byun, Hye Ryoung,Ryu, Mee-Yi,Song, Jin Dong 한국진공학회 2013 Applied Science and Convergence Technology Vol.22 No.2

Migration-enhanced epitaxy 성장한 InAs/GaAs 양자점(quantum dots)의 광학적 특성을 PL (photoluminescence)과 Time-resolved PL 이용하여 분석하였다. InAs 양자점은 In을 9.3초 공급하고 5초 차단한 후 As을 3초, 4초, 6초, 또는 9초 공급하고 5초 차단하는 과정을 3회 반복하여 성장하였다. As을 3초 공급한 시료의 PL 피크는 1,140 nm에서 나타나고, PL 세기는 다른 세 시료에 비해 매우 약하게 나타났다. As 공급시간을 3초에서 증가하였을 때 모든 PL 피크는 1,118 nm로 청색이동하여 나타났으며, PL 세기는 증가하였다. As을 6초 공급한 시료의 PL 세기가 가장 강하게 나타나고, 반치폭(full width at half maximum)도 가장 좁게 나타났다. 이러한 결과는 양자점의 밀도와 균일도(크기변화)로 설명된다. 또한 발광파장에 따른 PL 소멸시간은 PL 피크 근처에서 가장 길게 나타났다. The luminescence properties of InAs/GaAs quantum dots (QDs) grown by a migration enhanced epitaxy method have been investigated by using photoluminescence (PL) and time-resolved PL measurements. The MEE method supplies materials in a series of alternate depositions with migration enhancing time between each deposition. After In source was supplied for 9.3 s, the growth was interrupted for 5 s. Subsequently, As source was open for 3 (AT3), 4(AT4), 6 (AT6), or 9 s (AT9), and the growth was interrupted for 5 s again. This growth sequence was repeated 3 times for the growth of InAs QDs. The PL peak of the AT3 was 1,140 nm and the PL intensity was very weak compared with that of the other three samples. The PL peak of all samples except the AT3 sample was 1,118 nm, which is blueshifted from 1,140 nm, and the PL intensity was increased compared to that of the AT3. These results can be explained by the increased QD density and the improved QD uniformity. The AT6 sample showed the strongest PL intensity and the narrowest full width at half maximum. The PL decay time of AT6 increased with increasing emission wavelength from 940 to 1,126 nm, reaching a maximum decay time of 1.09 ns at 1,126 nm, and then decreased as the emission wavelength was increased further.

다층 성장한 InAs/InAlGaAs 양자점의 광학적 특성

오재원,권세라,류미이,조병구,김진수,Oh, Jae-Won,Kwon, Se-Ra,Ryu, Mee-Yi,Jo, Byoung-Gu,Kim, Jin-Soo 한국진공학회 2011 Applied Science and Convergence Technology Vol.20 No.6

자발형성법으로 InP (001) 기판에 성장한 InAs/InAlGaAs 양자점(QDs, quantum dots)의 광학적 특성을 PL (photoluminescence)과 TRPL (time-resolved PL)을 이용하여 분석하였다. InAs 양자점 시료는 single layer InAs/InAlGaAs QDs (QD1)과 7-stacked InAs/InAlGaAs QDs (QD2)를 사용하였다. 저온(10 K)에서 QD1과 QD2 모두 1,320 nm에서 PL 피크가 나타났으며, 온도를 300 K까지 증가하였을 때 각각 178 nm와 264 nm의 적색편이(red-shift)를 보였다. QD1의 PL 소멸시간은 PL 피크인 1,320 nm에서 1.49 ns이고, PL 피크를 중심으로 장파장과 단파장으로 이동하면서 점차 짧아졌다. 그러나 QD2의 PL 소멸시간은 발광파장이 1,130 nm에서 1,600 nm까지 증가할 때 1.83 ns에서 1.22 ns로 점진적으로 짧아졌다. 이러한 QD2의 PL과 TRPL 결과는 평균 양자점의 크기가 InAs/InAlGaAs 층이 증가함에 따라 점차 증가하기 때문으로 single layer인 QD1에 비해 양자점 크기의 변화가 더 크기 때문으로 설명된다. Self-assembled InAs/InAlGaAs quantum dots (QDs) grown on an InP (001) substrate have been investigated by using photoluminescence (PL) and time-resolved PL measurements. The single layer (QD1) and seven stacks (QD2) of InAs/InAlGaAs QDs grown by the conventional S-K growth mode were used. The PL peak at 10 K was 1,320 nm for both QD1 and QD2. As the temperature increases from 10 to 300 K, the PL peaks for QD1 and QD2 were red-shifted in the amount of 178 and 264 nm, respectively. For QD1, the PL decay increased with increasing emission wavelength from 1,216 to 1,320 nm, reaching a maximum decay time of 1.49 ns at 1,320 nm, and then decreased as the emission wavelength was increased further. However, the PL decay time for QD2 decreased continuously from 1.83 to 1.22 ns as the emission wavelength was increased from 1,130 to 1,600 nm, respectively. These PL and TRPL results for QD2 can be explained by the large variation in the QD size with stacking number caused by the phase separation of InAlGaAs.

Interleukin-10의 기도 과민반응억제와 항염효과

오재원,Oh, Jae Won 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.8

소아천식의 알레르겐 특이 면역요법의 효과

오재원 ( Jae Won Oh ) 대한소아알레르기호흡기학회 2005 소아알레르기 및 호흡기학회지 Vol.15 No.1

RSV나 인플루엔자 A형 바이러스에 감염된 비천식 소아에게 비인두 흡인액의 Interleukin - 11 , Interferon - γ치와 eosinophil cationic protein 치의 비교

오재원(Jae Won Oh),이하백(Ha Baik Lee),박일규(Il Kyu Park),강정옥(Jung Oak Kang) 대한천식알레르기학회 2000 천식 및 알레르기 Vol.20 No.1

N/A Background: Infection with respiratory virus has been shown to exacerbate asthma in humans. However, the role of a respiratory virus in the pathogenesis of chronic asthma and/or wheezing in young children has not been clearly defined. The objective of this study was to determine whether respiratory virus infections such as RSV, and influenza A virus are related to the productions of IL-11, IFN-γ, and ECP levels in nasopharyngeal secretions. Method: We compared IL-11, IFN-γ, and ECP levels in nasopharyngeal secretions from 38 non-asthmatic wheezing children with viral infections (RSV in 21 children, influenza A virus in 17 children), and 16 non-asthmatic healthy children who were included as the controls. IL-11, and IFN-y levels were analysed by ELISA. ECP concentrations were measured by monoclonal antibody-based fluorometric assay. Result. RSV infection in children induced a greater release of IL-11 in nasopharyngeal secretions than in influenza A virus infection, and in the controls. The release of IFN-γ levels in nasopharyngeal secretions from children with influenza A virus infection was significantly higher than in nasopharyngeal secretions from children with RSV. ECP levels of subjects with viral infection were significantly higher than in control children. Conclusion. This study demonstrated that RSV is a potent inducer of IL-11 elaboration in nasal epithelium and that IL-11 is an important mediator in the pathogenesis of RSV infection. Increased IFN-γ production in response to the influenza A virus infection may be related to effective Th1 responses.

비만아에서 천식과 Leptin의 상관성

오재원 ( Jae Won Oh ) 대한소아알레르기호흡기학회 2006 소아알레르기 및 호흡기학회지 Vol.16 No.4