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중심-측두엽 극파를 보이는 양성 소아 간질 환자에서 항경련제 투여의 유효성
오미혜,김수영,서원희,피대훈,최병민,은백린,Oh, Mee Hye,Kim, Soo Young,Seo, Won Hee,Pee, Dae Hun,Choi, Byung Min,Eun, Baik-Lin 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.9
목 적 : 중심-측두엽 극파를 보이는 양성 소아 간질은 소아간질의 6-16%를 차지하며 2-13세 사이에 발병하나 사춘기 이후에는 자연 소실된다. 이들 환아들에게 항경련제를 투여하는 것에 대해 효과 및 효율성에서 상이한 결과가 많이 보고되고 있다. 이에 본 연구는 항경련제를 투여한 군과 항경련제를 투여 받지 않은 군에서 그 약물 효과 및 효율성에 관해 조사하였다. 방 법 : 고대의료원 소아신경클리닉에서 임상 증상 및 뇌파 검사상 중심-측두엽 극파를 보이는 양성 소아 간질로 진단된 환아 56명을 대상으로 하였다. 대상 환아들을 항경련제 투여군과 항경련제 비투여군으로 분류한 후 의무기록지 분석을 통한 후향적 조사로 두 군간의 인구역동학, 항경련제 투여의 기준, 임상양상 등을 확인하였다. 결 과 : 양 군간 성별, 지역별, 연령별 차이는 없었다. 첫 경련이 시작된 연령, 경련의 주, 야간 비율, 경련 지속 시간 등에 있어서도 양 군간 차이는 보이지 않았다. 항경련제 투여군이 항경련제 비투여군에 비해 경련의 빈도가 줄었으나(P<0.05) 항경련제 비투여군과 투여군간의 장기적 예후 차이는 볼 수 없었다. 결 론 : 중심-측두엽 극파를 보이는 양성 소아 간질 환아들은 항경련제의 투여 여부와 무관하게 양성 예후를 보이며 경련 지속 기간에도 뇌 손상이나 신체 상해를 입을 만한 합병증을 나타내지 않으므로 이 질환에 대한 본인 혹은 보호자의 충분한 이해가 선행된다면 항경련제를 1차 치료로 선택하지 않아도 무난하다고 여겨진다. Purpose : Benign childhood epilepsy with centrotemporal spikes(BECT) is characterized by an excellent prognosis. Therefore, the necessity for the use of antiepileptic drugs is controversial. The object of this study is to know about the long-term follow-up of BECT, comparing daily treatment with antiepileptic drug(AED) versus no medication. Methods : We retrospectively studied 56 cases of BECTs, examined at Pediatric Neurology Clinic, Korea University Medical Center as reference study time, August 2002. Thirty-eight patients didn't have mediation(group I), while eighteen patients received one or two AED(group II). We evaluated demographics, clinical manifestations at diagnosis, EEG findings and clinical courses in groups I & II. Results : There was no significant differences of sex, age, seizure frequency, seizure type, seizure onset time, family history and EEG findings between group I & II. The reasons to start AED were : parents' anxiety(three cases), frequent seizure(12 cases) and daytime seizure(three cases). There was no evolution of status epilepticus and no difficulty in school performance. Conclusion : AED treatment was of no advantage and long-term prognosis was good regardless of treatment strategy. So it is advisable not to choose AED as the first line of therapy, provided that the patient himself/herself or the family understands the benign nature of BECT.
대퇴부의 횡문근내에서 발생한 과립세포 종양의 세침흡인 세포학적 소견 - 1 증례 보고 -
오미혜,강신광,Oh, Mee-Hye,Khang, Shin-Kwang 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.1
Granular cell tumor is mostly benign and thought to be of Schwann ceil origin. The head and neck, particularly tongue, breast, and upper respiratory tract are frequently involved. Recently, we have experienced a case of granular cell tumor of the right thigh in a 30-year old male, diagnosed by fine needle aspiration cytology which revealed distinct cytologic features The smear revealed cellular aspirates with clear back-ground. The tumor cells showed uniform small nuclei and abundant eosinophilic, granular cytoplasm with hazy cell border. Mitoses were not found.
자동차 경량 대체소재로서의 Polycarbonate Grazing의 특성에 관한 연구
오미혜(Mee-Hye Oh),윤여성(Yeo-Seong Yoon),강민경(Min-Kyung Kang),이춘범(Chun-beom Lee),신재섭(Jae-Sup Shin),지영존(Young-Jon Ji) 한국자동차공학회 2005 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2005 No.5_2
Polycarbonate is a highly versatile material that offers unique properties for to styling, design-driven challenges and reduces the weight compared to glass in today's highly competitive automotive market. In this study, to use polycarbonate for automobile window, we studied hard coating on polycarbonate and checked over application possibility in automobile. We formed coating layer using sol-gel process then we found the compound condition which have the superior property. We examined property of coating layer as various ratio, selectivity of solvent, aging time, etc. As a result of this sol-gel process, we have good coating layer. In this work, also we preferentially tried to manufacture automobile window.
이하선의 선방세포암종의 세침흡인 세포학적 소견 - 1예 보고 -
이원애,전이경,오미혜,강신광,Lee, Won-Ae,Chun, Yi-Kyeong,Oh, Mee-Hye,Khang, Shin-Kwang 대한세포병리학회 1992 대한세포병리학회지 Vol.3 No.2
Acinic cell carcinoma is a rare salivary gland tumor of low-grade malignancy. It comprises only about 2.5% of all salivary gland tumors. We recently experienced a case of fine needle aspiration cytology of acinic cell carcinoma of the parotid gland. The characteristic cytopathologic features were 1) cellular aspirate consisting of monomorphic cells in large sheets or singly, 2) formation of acini and/or microcysts, 3) abundant granular cytoplasm with sharp cytoplasmic borders, 4) bland nuclei with micronucleoli, and 5) clear background.
A Case of Mediastinal Cavernous Hemangioma
이석열,박경배,오미혜,이승진,이철세,Lee, Seock-Yeol,Park, Kyung-Bae,Oh, Mee-Hye,Lee, Seung-Jin,Lee, Cheol-Sae Korean Association of Pediatric Surgeons 2009 소아외과 Vol.15 No.2
We report a case of cavernous hemangioma of the anterior mediastinum that was incidentally detected by chest radiography taken at a routine health check-up. A mass lesion was seen in the anterior mediastinum on computed tomography and magnetic resonance imaging. Direct surgical removal was performed for diagnosis and treatment through right thoracotomy. Histopathology confirmed the mass as a cavernous haemangioma. Post-operative course was uneventful.
문유진,김준혁,이영만,오미혜,조현득,Moon, Yoo-Jin,Kim, Jun-Hyuk,Lee, Young-Man,Oh, Mee-Hye,Cho, Hyun-Deuk 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.1
Purpose: Carcinosarcomas are rare neoplasms in which both malignant epithelial and mesenchymal elements are identified. We have found only twenty one cases of primary cutaneous carcinosarcoma in the English language literature. Therefore it has been difficult to diagnosis because its unclear etiology and low frequency. Methods: A 31-year-old young man with a protruding mass on his ankle dorsum was examined. The tumor was $7{\times}6{\times}3\;cm$ sized and arose from a burn scar. The mass was wide excised and applied split thickness skin graft. Characteristic pathologic finding was a mixture of squamous cell carcinoma and malignant fibrous histiocytoma. Results: Three months after the operation, the patient died of multiple metastasis to the liver, lung and finally of sepsis despite adjuvant chemotherapy and adjuvant radiotherapy. Conclusion: If a metastatic cutaneous carcinosarcoma is diagnosed, wide excision is required. There should be more aggressive management to minimize the risk of recurrence. Further research into the etiology and pathophysiology of the disease and a more careful differential diagnosis may allow improvement in treatment.