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자궁내막증과 자궁선근증에서 금속단백효소 및 금속단백효소 저해자의 발현 - 에스트로겐 수용체 및 프로게스테론 수용체 발현과의 비교
엄대운 ( Dae Woon Eom ),강길현 ( Gil Hyun Kang ),박한뫼 ( Han Moie Park ),이상수 ( Sang Su Lee ),손우석 ( U Seog Son ),이옥준 ( Ok Jun Lee ),김정란 ( Jung Ran Kim ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10
목적 : 자궁내막증과 자궁선근증에서 월경주기에 따른 금속단백효소-2 (matrix metalloproteinase 2, MMP-2)와 금속단백효소 저해자 (inhibitor of metalloproteinase 2, TIMP-2)의 발현양상을 에스트로겐 수용체 (estrogen receptor, ER), 프로게스테론 수용체 (progesterone receptor, PR)의 발현양상과 비교함으로써 두 질환의 발생기전에 있어서 MMP-2와 TIMP-2의 Objective : This study was aimed to investigate the role of matrix metalloproteinase-2 (MMP-2) and inhibitor of metalloproteinase-2 (TIMP-2) for pathogenesis of endometriosis and adeonomyosis by the comparison of their expressions with those of ER (nuclea
Low-grade Mucinous Cystic Tumor Associated with Endo-metriosis in the Cecum
Dae-Woon Eom(엄대운),Gil Hyun Kang(강길현),Sang Wook Yi(이상욱),Seung Mun Jung(정승문),Jin Ho Kwak(곽진호),Hyuk Jai Jang(장혁재),Kun Moo Choi(최건무),Myung Shick Han(한명식) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.1
We report here on an unusual case of mucinous cystic tumor that was associated with endometriosis in the cecum. A 45-year-old woman was admitted to the hospital due to her 5 day history of right lower quadrant abdominal pain with a mild fever. A laparotomy was performed under the clinical impression of the tubo-ovarian abscess. A relatively well defined a multi-locular cystic mass (8.0×8.0×7.0 cm) filled with white-to-yellow thick mucoid material was found in the wall of the cecum. The right ovary and fallopian tube showed marked fibrous adhesion to the external surface of the cecal mass. A right hemicolectomy and salpingo-oophorectomy were performed. Histologically, the tumor was similar to those of ovarian borderline mucinous tumor, the intestinal type, and the mucinous epithelium of the tumor was merged with the endometriotic epithelium and stroma. On immunostaining, the CK20 positive mucinous epithelium was well demarcated from the CK7 endometriotic epithelium. This is the first case of low-grade mucinous cystic tumor intimately associated with intestinal endometriosis in the cecum.
유방의 낭성과다분비관내암종의 세침흡인 세포학적 소견 - 2예 보고 -
차희정,엄대운,서재희,Cha, Hee-Jeong,Eom, Dae-Woon,Suh, Jae-Hee 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.1
Cystic hypersecretory carcinoma of the breast is a rare variant of ductal carcinoma of breast, first described in 1984 by Rosen and Scott. Histologically, it is characterized by the formation of dilated ducts and cysts containing an eosinophilic secretory product resembling thyroid colloid. Cytologic findings show a few clusters of atypical ductal epithelial cells in amorphous proteinaceous material with clacking artifact. Differential diagnosis include mucinous carcinoma and benign mucocele-like tumor. We present two cases of fine needle aspiration cytology of cystic hypersecretory intraductal carcinoma of the breast with a review of the literature.
정선미 ( Son Mi Chung ),이은영 ( Eun Young Lee ),이창근 ( Chang Keun Lee ),엄대운 ( Dae Woon Eom ),유빈 ( Bin Yoo ),문희범 ( Hee Bom Moon ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.1
Cryptococcosis, a disseminated illness due to Cryptococcus neoformans in most case, is an opportunistic systemic fungal infection that frequently infects the immunosuppressed host. Although it can cause disease in immunocompetent as well as immunocompromised hosts, the later group, particulary those with cell-mediated immune defects, are the greatest risk for severe disseminated disease. Cryptococcal tenosynovitis is extremely rare, with only 2 cases previously documented in the English literature. In this paper we report a case of cryptococcal tenosynovitis with multiple lung nodules in the setting of cryptococcemia in a patient with Wegener`s granulomatosis who has been treated with steroid, oral cyclophosphamide for one year.
최건무(Kun Moo Choi),박기영(Ki Young Park),엄대운(Dae Woon Eom) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.6
Traditionally, it has been emphasized that hemolytic disease was the primary cause of gallstones (cholelithiasis) in most young patients. In recent years, gallstones and common bile duct calculi have been increasingly diagnosed in infants and children, unrelated to hemolytic diseases. On the matter, the World Health Organization (WHO) classified intraepithelial neoplasia (dysplasia) of gall bladder as one of the precursor lesions of invasive cancer. The following article describes the case of a 2-year-old girl who had a laparoscopic cholecystectomy due to cholelithiasis and the pathologic diagnosis was chronic cholecystitis with diffuse, mild mucosal dysplasia.
정재락 ( Jae Rak Chung ),윤제헌 ( Je Hyun Yoon ),이상곤 ( Sang Gon Lee ),엄대운 ( Dae Woon Eom ),우영주 ( Young Joo Woo ),최승원 ( Seung Won Choi ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.3
Primary Sjogren`s syndrome is a chronic autoimmune disorder characterized by xerostomia and keratoconjunctivitis sicca result from lymphocytic infiltrations of salivary and lacrimal glands. It may accompany by the wide spectrums of extraglandular symptoms, such as musculoskeletal, pulmonary, renal, intestinal, hematologic, and nervous system. However, overt cardiac manifestations are very rare and are documented only a few cases sporadically. We report a patient with primary Sjogren`s syndrome who developed reversible congestive heart failure as part of a myocarditis. A 39-year-old woman with primary Sjogren`s syndrome developed fatigue, dyspnea, and abdominal discomfort. An echocardiography revealed global hypokinetic left ventricle with markedly decreased ejection fraction (EF=39%), abnormal restrictive filling pattern, secondary tricuspid valve insufficiency and no pericardial effusion or thickening. A myocardial biopsy disclosed myocardial degeneration with lymphocyte infiltration. Following treatment with digitalis, diuretics, ACE inhibitor and corticosteroid, the symptoms of congestive heart failure improved. A repeat echocardiography showed an improved ventricular contractility and recovered both diastolic (normalized E/A ratio) and systolic (EF=50%) functions.