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Diagnosis of Systemic Lupus Erythematosus During Medical Follow-up After Urinary Screening
윤소진,송지은,신재일,정일천,이재승,심효섭,정현주,Yoon, So-Jin,Song, Ji-Eun,Shin, Jae-Il,Jeong, Il-Cheon,Lee, Jae-Seung,Shim, Hyo-Sup,Jeong, Hyeon-Joo Korean Society of Pediatric Nephrology 2008 Childhood kidney diseases Vol.12 No.2
16세 여아가 학교 소변 검사에서 단백뇨와 현미경적 혈뇨가 나타났으며 신생검에서 감염 후 사구체 신염으로 추정되었다. 그러나 단백뇨는 안지오텐신 효소 억제제 치료에도 반응하지 않았다. 6개월 후 경부 림프절염이 나타났고 목 주위 림프절생검에서 아급성 괴사성 림프절염 소견을 보였다. 이후 2개월 후, 환아는 얼굴의 발진과 혈소판 감소증을 보였다. 재 신생검에서 루프스 신염 class IV 소견을 보였다. 환아는 충격 methylprednisolone(500 mg/일) 3일간 정주 후 경구 deflazacort로 유지하였으며, 이와 함께 cyclophosphamide(1 g/$m^2$)를 월 1회 정주 충격 요법을 6회 실시하였다. 이에 본 저자들은 학교 집단 요 검사 이상으로 추적검사 중 전신 홍반 루푸스로 진단이 되었던 증례를 보고하는 바이다. A 16-year-old girl presented with proteinuria and microscopic hematuria detected through mass urinary screening and was diagnosed as having suspected postinfectious glomerulonephritis by renal biopsy. However, heavy proteinuria did not respond to angiotensin converting enzyme inhibitor therapy. After 6 months, cervical lymphadenitis developed and a neck node biopsy showed subacute necrotizing lymphadenitis. After an additional 2 months, she developed facial erythema and thrombocytopenia. A repeat renal biopsy demonstrated lupus nephritis class IV. She was treated with pulse methylprednisolone(500 mg/day intravenously for 3 consecutive days) followed by oral deflazacort and monthly intravenous cyclophosphamide pulse(1 g/$m^2$) for 6 months. We report a case diagnosed as systemic lupus erythematosus(SLE) during medical follow-up after urinary screening.
이상국 ( Sang Kook Lee ),이상훈 ( Sang Hoon Lee ),김송이 ( Song Yee Kim ),이우경 ( Woo Kyung Lee ),신동호 ( Dong Ho Shin ),방우대 ( Woo Dae Bang ),노송미 ( Song Mi Noh ),심효섭 ( Hyo Sup Shim ),박병훈 ( Byung Hoon Park ),이경종 ( 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.70 No.2
We report a case of Caplan`s Syndrome, which presented as multiple pulmonary nodules. A 58-year-old male was admitted to hospital due to multiple pulmonary nodules. In addition, the patient presented with multiple arthritis, and dyspnea on exertion. Rheumatoid arthritis had been diagnosed 35 years ago. The patient had worked as a stonemason for 20 years. Computed Tomography (CT) revealed numerous well-defined tiny nodules scattered in both lungs, which was suspicious of miliary tuberculosis or malignancy. The patient was started on antituberculous medications and referred to our hospital. First, a transbronchial lung biopsy was performed, which showed no evidence of granuloma. It was our opinion that the biopsy was insufficient, and a follow-up video-associated thoracoscopy was performed. The pathological report determined necrotizing granulomatous inflammation and silicosis on background. According to imaging studies, pathologic reports, and clinical symptoms, we concluded that the patient had Caplan`s syndrome. We controlled his rheumatic medications, and instructed him to avoid exposure to hazardous dust.
김송이 ( Song Yee Kim ),이경종 ( Kyung Jong Lee ),이상훈 ( Sang Hoon Lee ),이상국 ( Sang Kook Lee ),박병훈 ( Byung Hoon Park ),정지예 ( Ji Ye Jung ),손지영 ( Ji Young Son ),윤여운 ( Yoe Wun Yoon ),심효섭 ( Hyo Sup Shim ),강영애 ( 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.1
We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe which was detected on the chest radiography being examed due to recurrent cough for 1 year. The computed tomography (CT) revealed a spiculated nodule containing air-bronchogram, which was suspicious of malignancy. We performed transbronchial biopsy and the pathology showed granulomatous inflammation with caseous necrosis. Under the presumptive diagnosis of pulmonary tuberculosis, we started anti-tuberculous medication including isoniazid, rifampin, ethambutol, and pyrazinamide. In one month, however, the sputum culture was positive for Mycobacterium intracellulare. The follow-up chest CT showed slight aggravation of the previous lesions. Under the final diagnosis of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule, we changed the regimen to rifampin, ethambutol, and clarithromycin. The follow-up chest CT after the completion of treatment, revealed resolution of the previous lesions.
가로쓰기 한글의 글자꼴과 글줄이 인지속도에 미치는 영향
이병근,이진호,심효섭 東西大學校 1997 동서논문집 Vol.3 No.1
This study investigated the effect of character form and the Numbers of characters per line on Readability of Hangul characters and words horizontal printing. The results were as follows. In canceling tests. (1) the speeds of character canceling were faster in the order of elongated form condensed form and original form conditions, and (2) the speeds of word canceling were in the order of elongated, original and condensed form conditions. But in a reading task, (3) the order of the Readability were [40>35>30] in number of characters per line condition and [original>elongated>condensed] in character form conditions. The above indicates that original form with 40 characters per line is the best combination for horzontal Haugul printing.