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신준한(Joon Han Shin),오제열(Je Yol Oh),박효진(Hyo Jin Park),정준표(Jun Pyo Chung),이관식(Kwan Sik Lee),이상인(Sang In Lee),박인서(In Suh Park),최흥재(Heung Jae Choi) 대한내과학회 1993 대한내과학회지 Vol.45 No.1
N/A Background: Gastric cancer associated with pregnancy is rare. Because of the similarity of symptoms between gastric cancer and preganancy, limitations in diagnostic approaches and difficulties in saving both mother and fetus, the prognosis is poor. Therefore, we analyzed the clinical features of gastric cancer associated with pregnancy, appropriated diagnostic approaches and practical guidlines for treatment. Method: We collected 23 cases of gastric cancer detected during pregnancy or within 12 months after delivery from January, 1980 to June, 1992. And age of patients, approaches of diagnosis, stage of cancer, pre- dominant histological features, results of surgical and obstetric treatment, and prognosis were analyzed according to the stage of pregnancy. Results: 1) Mean age of the patients at the time of diagnosis of the gastric cancer was 29.0±3.0 years old. Age range was 20-29 years old in 14 cases and 30-39 years in 9 cases. 2) The common presenting symptoms and signs were vomiting (52.2%), nausea (47.8%) and epigastric pain (47.8%). Mean duration from symptom onset to diagnosis was 6.5±7.8 months. 3) The percentages of patients diagnosed by endoscopic examination and barium study was 91.3% and 8.7%, respectively. In 5 cases, the distant metastases were found incidentally and then the primary focus was diagnosed by endoscopic examination or barium study. 4) Early gastric cancer was detected in 13.0% and advanced gastric cancer in 87.0%. In early gastric cancer, one case was found during pregnancy. 5) The histological features of gastric cancer were adenocardinoma in all cases and the types were poorly differentiated cell type (38.1%) and signet ring cell type (69.1%) 6) The treatment for gastric cancer was performed by surgery only in 21.7% and by combined surgery and chemotherapy in 21.7%. 7) The obstetric outcomes in patients diagnosed during pregnancy were normal spontaneous delivery in one case, preterm vaginal delivery in two cases, induced abortion in four cases and spontaneous abortion in one case. Conclusion: As the results show most of the gastric cancers associated with pregnancy was found in advanced state and their prognosis were grave. But same cases were early gastric cancers and in some cases complete resection was possible. Therefore, in order to improve the prognosis of gastric cancer associated with pregnancy, early diagnosis by endoscopy and appropriate treatment are emphasized.
외삽기법을 이용한 안테나의 원 ${\cdot}$ 근역장 절대이득 측정시스템 개발
신준,강찬구,김정환,정낙삼,Shin, Joon,Kang, Chan-Koo,Kim, Jeong-Hwan,Chung, Nak-Sam 대한전자공학회 1990 전자공학회논문지 Vol. No.
외삽기법을 시용하여 실내의 소형 안테나 레이지에서 안테나 이득을 측정할 수 있는 시스템을 개발하였다. 외삽기법은 안테나의 절대이득 측정에 보통 사용되는 2-안테나 방법과 유사한데 가까운거리 구간에서 수신되는 신호의 크기를 거리의 함수로 연속적으로 측정한 후 외삽법을 사용한 신호처리로 무한거리에서 수신되는 신호의 크기를 계산함으로써 안테나의 원역장 이득을 구할 수 있다. 또한 원역장 이득과 근역보정인자를 결합하여 근역장 이득을 안테나로부터의 거리의 함수로 구하는 것도 가능하다. 이 외삽기법을 사용하여 측정한 표준이득 혼 안테나와 OEC 안테나의 이득 측정결과를 고찰하였다. An antenna gain measurement system using an extrapolation technique is described. The technique is similar to the usual two-antenna method for absolute gain measurement system, but involves the measurement of the received signal as a function of seperation in short distances, and the signal-versus-seperation data is processed in a way that allows an extrapolation of the signal to "infinite" seperation. In this technique it is possible to obtain the near field gain as function of distance by combining the far field gain and a proximity correction factor. The results of gain measurements of standard gain horn antennas and OEG (open ended waveguide) antennas are also presented.
신준,오재응,Shin, Joon,Oh, Jae-Eung 대한기계학회 1992 대한기계학회논문집 Vol.16 No.10
본 연구에서는 자동차의 발달에 따른 정비 전문가의 상대적인 능력 감퇴를 보 완하고 진단의 정확성을 높일 수 있도록 소음계측에 의한 인공 지능적 뉴로-퍼지 진단 기법을 연구하였다. 이를 위하여 진단결과에 영향을 미치는 많은 작용변수와 다양한 차량상태 등을 고려함으로서 보다 신뢰성 있는 결과를 산출해내기 위한 퍼지(fuzzy) 추론 방식의 판단법을 도입하였으며, 진단이 실패했을 경우나 입력된 데이터가 충분하 지 못할 경우에 시스템 자체의 지식을 확장시켜 나갈 수 있도록 해밍네트(hamming net )에 의한 패턴인식 기법을 적용하였다. 그리고 컴퓨터 시뮬레이션과 자동차를 대상 으로 고장진단 실험을 실시하여 기존의 진단기법과의 비교를 통한 뉴로-퍼지 진단기법 의 효율성과 알고리즘의 타당성을 검증하였다. In the diagnostic process for automobile, Neuro-Fuzzy technique was compared with the conventional diagnostic method for the verification of performance, and proto-type system was developed. For the utilities of the system, 1/3 octave filter(band-pass filter) and A/D converter were used for data acquisition and then data were analyzed using octave band processing and pattern recognition using hamming network algorithm. In order to raise the reliability of the diagnostic results by considering many operating variables and condition of automobile to be diagnosed, fuzzy inference technique was applied in combining several information. The validation of this diagnostic system was examined through computer simulation and experiment, and it showed an acceptable performance for diagnostic process.
진동법에서 가변 특성 비를 이용한 혈압 추정 알고리즘의 개발
신준,Shin, Joon 대한의용생체공학회 2009 의공학회지 Vol.30 No.6
In this paper, variable characteristic ratio algorithm based on oscillometric method is proposed to enhance the accuracy of blood pressure measurement. We combined the slope-based approach and fuzzy inference technique to change the characteristic ratios of height-based method. The proposed algorithm was assessed on 255 measurements from 85 subjects and compared with the conventional height-based algorithm. The testing results showed that the developed algorithm achieved an overall grade A for both systolic and diastolic blood pressures according to the BHS protocol. And, mean standard deviation between the observers and the developed algorithm were 5.71mmHg and 6.29mmHg for systolic and diastolic pressures respectively, which also fulfilled the AAMI criteria. In conclusion, this algorithm was successfully developed and recommended for further clinical trials with the wider adult population.
신준,김흥섭,오재응,Shin, Joon,Kim, Heung-Seob,Oh, Jae-Eung 대한기계학회 1994 대한기계학회논문집 Vol.18 No.9
With the improvement of standard of living, requirement for comfortable and quiet environment has been increased and, therefore, there has been a many researches for active noise reduction to overcome the limit of passive control method. In this study, active noise control is performed in a duct system using intelligent control technique which needs not decide the coefficients of high order filter and the mathematical modeling of a system. Back propagation algorithm is applied as an intelligent control technique and control system is organized to exclude the error microphone and high speed operational device which are indispensable for conventional active noise control techniques. Furthermore, learning is performed by organizing acoustic feedback model, and the effect of the proposed control technique is verified via computer simulation and experiment of active noise control in a duct system.
양호연,신준한,최종훈,안형준,Yang, Ho-Yeon,Shin, Jun-Han,Choi, Jong-Hoon,Ahn, Hyoung-Joon 대한안면통증구강내과학회 2005 Journal of Oral Medicine and Pain Vol.30 No.1
As people prefer to use right or left hand, some have preferred chewing side while others do not. Totally, 82 volunteers composed of students and staffs from Dental Hospital College of Dentistry Yonsei University participated in this study for the investigation of influence of preferred chewing habit, that has lasted for more than a year, on electromyographic(EMG) activity of masticatory muscles and bite force. Among the 82 volunteers, 46 had preferred chewing habit while the other 36 did not. Prior to the investigation, those with factors that could affect the study, such as, general disease, irregular dentition and malocclusion, were screened and excluded by questionnaire and clinical examination. The results were as follows: 1. There was no significant difference in EMG activities between chewing side and non-chewing side of preferred chewing subjects at rest as well as maximal voluntary contraction(MCV)(p>0.05). 2. Asymmetrical coefficient of temporal and masseter muscle EMG activities between preferred chewing subjects and non-preferred chewing subjects at rest was not significantly different(p>0.05). 3. Asymmetrical coefficient of masseter EMG activity was significantly higher(p<0.05) than that of non-preferred chewing subjects at MCV, whereas that of anterior temporal muscle showed no difference(p<0.05). 4. In preferred chewing subjects, there was no significant difference in average bite force and occlusal contact area between chewing side and non-chewing side(p>0.05). 5. There was no significant difference in Asymmetrical coefficients of average bite force and occlusal contact area between preferred chewing subjects and non-preferred chewing subjects (p>0.05). Consequently, preferred chewing habit can be considered as physiological asymmetry with normal function rather than to have influence on EMG muscle activity of masticatory muscles, average bite force and occlusal contact area. Objective standardization to differentiate preferred chewing subjects and non-preferred chewing subjects should be established in the further study.
신정숙 ( Jeoung Sook Shin ),김기찬 ( Ki Chan Kim ),김동훈 ( Dong Hoon Kim ),김세란 ( Sei Rhan Kim ),박진주 ( Jin Ju Park ),신준한 ( Joon Han Shin ),황교승 ( Gyo Seung Hwang ) 전북대학교 의과학연구소 2011 全北醫大論文集 Vol.35 No.2
J wave syndrome is a deflection with the dome or the hump morphology in the same direction as R wave and immediately followed the QRS complex on the surface ECG. It is known as an abnormalities in the manifestation of the transient outward current (Ito)-mediated J wave. It includes Brugada syndrome, early repolarization syndrome, arrhythmia associated hypothermia and the ST-segment elevation myocardial infarction. Several lines of evidence have suggested that J wave syndrome closely associated with idiopathic Ventricular tachycardia (VT) and Ventricular fibrillation (VF). We report one case of J wave syndrome in a 50 years old male who was a survivor of sudden cardiac death. He had suffered 2 times sudden cardiac death previously. At the visiting day, his electrocardiography (ECG) exhibited J waves in precordial leads (V1-V6), II, II, aVF and J-ST elevation at the same leads. Considering, recurrent sudden cardiac arrest, J wave on inferior, lateral lead on ECG, we conclude he has a J wave syndrome.
급성심근경색에서 Troponin T 와 경색의 크기와의 상관관계
서창희(Chang Hee Suh),김한수(Han Soo Kim),강한걸(Han Geol Kang),신준한(Joon Han Shin),탁승제(Seung Jae Tahk),이승호(Seong Ho Lee),최병일(Byung Il William Choi) 대한내과학회 1997 대한내과학회지 Vol.52 No.1
N/A Objectives: The estimation of infarct size has been important in evaluation of prognosis of the patients who had acute myocardial infarction. The infarct size estimated by the thallium-201 SPECT has been known to correlate with the prognosis of patient. The enzymatic estimation by the total release of creatine kinase isoenzyme MB(CK-MB) has been widely used in estimating infarct size clinically, but inconvienent and not cardiospecific. Recently, serum troponin T, cardiospecific myofibrillar protein, has been used in the diagnosis of acute myocardial infarction, and used in the estimation of reperfusion following myocardial infarction. To assess the role of the late troponin T peak concentration on the estimation of infarct size, this prospective study was carried out. Methods: The patients with acute myocardial infarction who were admitted, within 48hours after the onset of chest pain, to Ajou University Hospital between April 1995 and August 1995 were evaluated. All patients were divided into anterior and inferior infarct and checked serum troponin T and CK-MB serially, and underwent stress Thallium-201 SPECT 1 week after infarction, In each group, we assessed the correlation of the late toponin T peak concentration, the total release of CK-MB, and the infarct size estimated by thallium-201 single photon emission computed tomography(SPECT). Results: 1) The eligible subjects consisted of 22 patients (17 men and 5 women), and age ranged from 29 to 77 years(mean 57.8±12.5 years). 2) The mean arrival time to the hospital after the onset of chest pain was 15.5±13.2 hours. The 19 patients had at least one risk factor for coronaryartery disease. 3) The late troponin T peak concentration and the total release of CK-MB in patients with anterior infarction were not different from those with inferior infarction. The infarct size estimated by the thallium-201 SPECT in patients with anterior infarction was larger than patients with inferior infarction The left ventricular ejection fraction in anterio infarction was lower than inferior infarction. 4) The late troponin T peak concentration ha: positive correlation with the infarct size estimated by the thallium-201 SPECT in the total patients, and both patients with anterior infarction and inferio infarction. 5) The total release of CK-MB correlated with the infarct size estimated by the thallium-20 SPECT in the total patients, and the patients of inferior infarction. Conclusion: The late troponin T peak concentration was more accurate than the total release o CK-MB in the estimation of infarct size. Therefore, when the patient arrived to the hospital less than 48hr after the onset of chest pain, the late troponin T peak concentration is useful in the decision and evaluation of therapeutic intervention and in the prediction of prognosis.
운동부하검사 중 과도한 수축기 혈압상승을 보이는 환자에서 Nitric Oxide/cyclic-GMP경로를 통한 내피세포 기능의 장애
박인휘 ( In Whee Park ),장혁재 ( Hyuk Jae Chang ),정재훈 ( Jae Hoon Chung ),신준한 ( Joon Han Shin ),최태영 ( Tae Young Choi ),최소연 ( So Yeon Choi ),윤명호 ( Myung Ho Yoon ),황교승 ( Gyo Seung Hwang ),탁승제 ( Seung Jae Tahk 대한내과학회 2003 대한내과학회지 Vol.65 No.1
Background : The diagnostic and prognostic implication of exaggerated blood pressure response to exercise has not been well characterized. Endothelial dysfunction has been demonstrated in patients with atherosclerosis or with risk factors for coronary art
박인서(In Suh Park),이상인(Sang In Lee),이관식(Kwan Sik Lee),박효진(Hyo Jin Park),신준한(Joon Han Shin),최홍재(Heung Jai Choi),권선옥(Seon Og Kweon),정준표(Jun Pyo jeong) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.2
Percutaneous endoscopic gastromy (PEG) and percutaneous endoscopic jejunostomy (PEJ) are used commonly for enteral feeding. Rut there were some reports of using PEG as an alternative to naso-gastrointestinal tube for decompression in parients with mechanical obstruction, particularly obstraction with malignancies involving the upper gastrointesrinal tract. Palliation is usually achieved by the placement of a nasogastric or nasointestinal tube. Hower these tubes tend to have some disadvantages which can be overcome with drainage PEG. In our experience, a 65 years old male patiert with pyloric obstruction due to advanced gastric cancer was successfly decompressed by drainage PEG. Thus, we present this case with supporting literatures.