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귀밑샘에 발생한 점액 화생을 동반한 만성 경화침샘염의 세침흡인 세포소견 -증례 보고-
석재연,정우희,허상범,김진,홍순원,Seok, Jae-Yeon,Jung, Woo-Hee,Fan, Xu Xiang,Kim, Jin,Hong, Soon-Won 대한세포병리학회 2005 대한세포병리학회지 Vol.16 No.2
Chronic sclerosing sialadenitis, also known as Kuttner tumor, is a benign chronic inflammatory lesion of the salivary gland. Here, we describe a case of chronic sclerosing sialadenitis with mucinous ductal metaplasia in a parotid gland, which was confused with low-grade mucoepidermoid carcinoma on aspiration cytology.
안소연 ( So Yun An ),정재연 ( Jae Youn Cheong ),김순선 ( Soon Sun Kim ),이다미 ( Da Mi Lee ),석재연 ( Jae Yeon Seok ),김영배 ( Young Bae Kim ),조성원 ( Sung Won Cho ) 대한내과학회 2010 대한내과학회지 Vol.78 No.4
백선은 봉삼, 봉황삼이라고 불리는 것으로, 비교적 쉽게 구할 수 있고 한약재료나 민간요법에 많이 사용된다. 현재까지 국내에서 백선을 복용한 후 소수의 예에서 독성 간염을 일으킨 것으로 보고되었으나 이로 인한 전격성 간부전으로 사망한 예는 보고된 바 없었다. 저자 등은 57세 여자에서 백선의 뿌리를 달인 물을 마시고 독성 간염을 보였으며 광범위한 간세포의 괴사로 인한 간부전으로 진행하여 사망한 예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. We report a case of fulminant hepatic failure related to ingesting Dictamnus dasycarpus. The patient had taken D. dasycarpus for 8 weeks after boiling down the root of D. dasycarpus in water, to promote health. The main symptoms and signs were general weakness and jaundice. Serology found no evidence of hepatitis A, B, or C infections. Imaging studies, including abdominal ultrasonography and abdominal computed tomography, did not reveal any bile duct structural abnormalities. Based on the RUCAM score (8 points), D. dasycarpus was the probable cause for the drug-induced liver injury. Despite meticulous monitoring and supportive care, the patient died by a progression to fulminant hepatic failure. This case indicates that D. dasycarpus can cause lethal outcomes by fulminant hepatic failure. (Korean J Med 78:490-494, 2010)
이준호 ( Jun Ho Lee ),이유미 ( Yu Mie Rhee ),석재연 ( Jae Yeon Seok ),박영년 ( Young Nyun Park ),차봉수 ( Bong Soo Cha ),이현철 ( Hyun Chul Lee ),임승길 ( Sung Kil Lim ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-
부신우연종은 부신과 무관한 문제로 시행한 영상학적 검사 도중에 우연히 발견된 부신의 종양을 말한다. 1980년대초 이후 고해상도 영상촬영술의 광범위한 이용의 결과로 부신우연종은 흔한 임상적인 문제가 되었다. 그러나 가성부신종양으로 불리는 몇 가지 경우는 부신종양으로 오인되는 수가 있는데, 대개 좌측에 위치하는 경우가 보고되어 있지만 우측 가성부신종양은 국내에서는 아직까지 보고된 바가 없다. 이에 저자 등은 우측에 위치한 부신종양으로 오인된 간세포암종 환자를 경험하게 되어 보고하는 바이다. Adrenal incidentalomas are adrenal masses discovered incidentally at the time of imaging procedures performed for nonadrenal problems. Since the early 1980s, incidentally discovered adrenal masses have become a common clinical problem as a result of the more idespread use of high resolution imaging procedures such as computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography. However, several conditions, called pseudoadrenal masses, can be occasionally misdiagnosed as an adrenal mass. Pseudoadrenal masses are usually located at the left side, but we have experienced a right-side pseudoadrenal mass. We report a patient with a hepatocellular carcinoma simulating a right adrenal mass. To our knowledge, this is extremely rare and the first case reported in Korea. It was possible to make a final diagnosis only after ultrasound-guided liver biopsy. (Korean J Med 69:S793-S797, 2005)
대장암 간전이 환자에 대한 간 절제시 선행화학요법이술 후 합병증에 미치는 영향
박지민(Ji Min Park),김봉완(Bong Wan Kim),석재연(Jae Yeon Seok),김영배(Young Bae Kim),백옥주(Ok Joo Paek),오승엽(Seung Yeop Oh),서광욱(Kwang Wook Suh) 대한외과학회 2011 Annals of Surgical Treatment and Research(ASRT) Vol.80 No.1
Purpose: Controversies regarding preoperative versus postoperative chemotherapy for patients having hepatic metastases of colorectal primary made us elucidate the safety of chemotherapy. By examining the histopathologic changes in the liver following preoperative chemotherapy and analyzing the relation between surgical outcomes and preoperative chemotherapy, we were able to answer whether preoperative chemotherapy is safe. Methods: We analyzed 38 patients who underwent chemotherapy before resection of hepatic metastasis from colorectal primary, retrospectively. Types of chemotherapy regimen were FL (5-FU+leucovorin), FOLFOX4 (oxaliplatin+5-FU+leucovorin), and FOLFIRI (irinotecan+5-FU+leucovorin). Results of liver function tests were compared before and after preoperative chemotherapy. One pathologist reviewed the degree of hepatic injury from resected specimens. Associations between the histological findings of hepatic injury and surgical outcomes and chemotherapeutic agents were examined. Results: Histopathologic analysis revealed severe liver injury was present in 12 patients (31.6%). In further detail, moderate to severe sinusoidal dilatation was found in 3 patients (25%), steatosis of more than 30% was identified in 9 patients (75%), and steatohepatitis Kleiner score of ≥4 in 5 patients (41.7%). Preoperative chemotherapy did not affect the biochemical profiles of liver function. The overall perioperative complication rate was 5.3% (n=2). There was no difference in postoperative morbidity or mortality from reported results following hepatectomy. Conclusion: We found preoperative chemotherapy definitely induced histopathologic changes of hepatotoxicities. Even so, preoperative chemotherapy did not increase morbidity or mortality after hepatic metastasectomy. Preoperative chemotherapy seems to be safe in performing curative hepatic resection for the metastases.