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윤장욱,박상훈,김은정,홍지현,이형석,오길찬,박철희,한태호,이동근,김종혁,박혜림,박충기 대한간학회 2003 Clinical and Molecular Hepatology(대한간학회지) Vol.9 No.3
Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disease of unknown cause associated with circulating autoantibodies and high serum globulin level. Systemic lupus erythematosus (SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complex, affecting multiple organs including the liver, kidney, and CNS. The difference between the hepatic involvement of SLE and autoimmune hepatitis has not been clearly defined in the past due to similarities in clinical and biochemical features. A scoring system for the diagnosis of AIH has been established, and AIH and SLE associated hepatitis have been defined as two different entities, although both have the same autoimmune features such as polyarthralgia, hypergammaglobulinemia and circulating autoantibodies. AIH has been considered to occur infrequently in SLE. We report two cases of AIH which simultaneously satisfied the criteria of SLE.(Korean J Hepatol 2003;9:231-235)
백승훈,장대영,김규원,이영철,이재영,장기택,박혜림 대한내과학회 2003 대한내과학회지 Vol.65 No.5
저자들은 식욕부진 및 복부동통을 주소로 내원한 51세 여자 환자에서 복부컴퓨터단층촬영에서 불균질한 조영증강을 보이며 광범위하게 전체 췌장에 전이된 파터 유두부종양 1예를 경험하였기에 문헌고차로가 함께 보고하는 바이다. Carcinoma of ampulla of Vater is a papillary neoplasm arising in the last centi meter of the common bile duct (CBD) where it passes through the wall of the duodenum and ampulla of Vater. We report the case of an ampulla of Vater cancer with the characteristic extensive invasion to the whole pancreas. A 53-year old female ws admitted to our hospital with chief complaint of epigastric pain, steatorrhea, and weight loss for 2 months. On physical examination, epigastric tenderness was detected. Gastroduodenoscopic biopsy from the mass revealed well differentiated adenocarcinoma. Abdominal CT demonstrated intraduodenal protruding mass with diffuse invasion to the whole pancreas. Arterial phase helical CT scan revealed intense heterogenous enhancement of entire pancreas. She underwent the Whipple procedure with total pancreatectomy. Final pathologic diagnosis was adenocarcinoma of ampulla of Vater with invasion of the whole with invasion of the whole pancreas and metastasis to the large number of regional lymph nodes.