미세먼지의 di(2-ethylhexyl) phthalate가 유도한 피부상피세포 사멸 신호전달기전 연구

박정배,김지윤,성정희,김용웅,이세중,Park, Jeong-Bae,Kim, Ji-Yun,Sung, Junghee,Kim, Yong-ung,Lee, Sei-Jung 한국환경과학회 2020 한국환경과학회지 Vol.29 No.3

Particulate matter with an aerodynamic diameter of less than 2.5 μM (PM_2.5) is one of the major environmental pollutants. Di(2-ethylhexyl) phthalate (DEHP), an endocrine disrupting chemical in PM_2.5, has been utilized for the manufacturing of polyvinyl chloride to increase the flexibility of final products. In the present study, we investigated the ecotoxicological effect of DEHP on the viability of skin keratinocytes (HaCaT). DEHP induced apoptotic cell death mediated by phosphorylation of extracellular signal-regulated kinase through the production of intracellular Reactive Oxygen Species (ROS). Interestingly, we found that DEHP induces the phosphorylation of the nuclear factor-kappa B responsible for the expression of cleaved caspase-3 as an executional cell death protease in HaCaT cells. On the basis of these results, we suggest that DEHP in PM_2.5 induces the apoptotic death of human keratinocytes via ROS-mediated signaling events.

방사선사진과 임상검사에서 하악 대구치 치근의 형태학적 구조 및 치조골 수준에 관한 비교연구

박정배,정진형,Park, Jung-Bae,Chung, Chin-Hyung 대한치주과학회 2004 Journal of Periodontal & Implant Science Vol.34 No.2

Periodontal defects of the furcation are characterized by several inherent anatomic factors that can make successful periodontal therapy difficult and results unpredictable. The severity and rate of occurrence of periodontal disease are directly related to the location of the furcation relative to the cementa-enamel junction and anatomical form of the root by limiting the accessibility and effectiveness of the periodontal instrumentation. This study investigated the reliability and accuracy of panoramic radiograph diagnoses of the periodontal state of mandibular molars, particularly regarding the diagnosis of furcation area periodontal defects, treatment planning, and prognosis prediction. This study examined a total of 110 teeth belonging to 33 subjects (19 male, 14 female) presenting with incipient to moderate periodontitis 4-7mmpocket depth. The alveolar bone level, length and width of the root trunk, and root separation angle were measured using the panoramic radiograph and compared to the results taken directly by retracting a full-thickness flap. The results of the study are as follows: 1. Data regarding the alveolar bone level of the mandibular first molar showed that the directly taken surgical measurements resulted in $5.1{\pm}0.9mm$ that was slightly deeper than the corresponding panoramic measurement resulted in $4.8{\pm}0.8mm$, but these differences were statistically insignificant (p>0.05). 2. The data of the directly taken surgical measurement of the mandibular second molar $(5.1{\pm}1.1mm)$ was slightly deeper than the corresponding panoramic measurement $(4.7{\pm}1.2mm)$, but these differences were statistically insignificant (p>0.05). 3. The measured values of the length and width of the mandibular first molar root trunks were determined to be $4.1{\pm}0.6mm$ and $7.3{\pm}0.9mm$, respectively, while the values of the mandibular second molar root trunks were determined to be $4.6{\pm}1.3mm$ and $7.6{\pm}0.9mm$ respectively. The differences between these values were found to be statistically significant (p<0.01). 4. The measured values of the root separation angle showed that the mandibular first molars averaged $34.5{\pm}4.4^{\circ}$, while the mandibular second molars averaged $23.0{\pm}10.0^{\circ}$. The differences between these values were found to be statistically significant (p<0.01).

Grafting 방법을 이용한 직접메탄올연료전지 애노드 촉매의 성능향상에 관한 연구

박정배(Park, Jung-Bae),한국일(Han, Kook-Il),김하석(Kim, Ha-Suck) 한국신재생에너지학회 2006 한국신재생에너지학회 학술대회논문집 Vol.2006 No.11

PtRu catalyst is most widely used as anode catalyst for a direct methanol fuel cell(DMFC). To promote the efficiency of the catalysts, it Is important to increase the triple phase boundary. In this study, we have tried to increase the triple phase boundaries in preparing electrocatalysts of the fuel cells, based on the process of grafting a proton-conducting agent onto the catalyst This grafted proton-conducting agent can act as an ionomer like Nafion, currently widely used ionomer. First, we have prepared the 80wt% PtRu/Ketjen Black electrocatalyst by an improved colloidal method. And, we have grafted methylsulfonate groups (-CH₂SO₃H) into the catalyst as proton-conducting agents. As results of cyclic voltammety and single cell test of the membrane electrode assembly (MEA), we can conclude that the activity of the grafted electrocatalysts is superior to that of conventional ones, in performance of DMFCs. For our further study, we will investigate the optimum ratio of catalyst/grafted proton conduct Ing agent with maximum performance of a DMFC.

청소년활동 참여동기에 따른 청소년지도자의 효과적인 리더십 형태

박정배(Park Jung-Bae),송병국(Song Byeong-Kug) 한국청소년정책연구원 2010 한국청소년연구 Vol.21 No.1

본 연구는 청소년활동 참여동기 수준이 다른 청소년들이 청소년활동에 지속적으로 참여하는데 영향을 미치는 청소년지도자의 리더십 유형을 실증적으로 밝히고 그 시사점을 찾기 위해 수행되었다. 연구의 목적을 달성하기 위해 서울경기지역 청소년수련관 10곳을 선정하여, 수련관에 소속된 동아리 회원 235명의 응답을 분석에 이용하였으며, SPSSWIN/ver14.0과 AMOS 4.0 통계프로그램을 사용하여 상관관계분석, 다중회귀분석, 경로분석을 통해 분석하였다. 연구결과 자유방임적리더십은 청소년활동 참여동기와 활동지속의지에 영향을 주지 못하는 것으로 나타났다. 또한 거래적리더십의 경우 외적동기를 통한 간접효과만을 갖는 것으로 나타났으며, 변혁적리더십의 경우 내적 동기를 통한 간접효과 뿐 아니라 무동기를 통한 간접효과를 갖는 것으로 나타났다. 특히 청소년활동 지속의지에 대한 효과 크기를 비교해본 결과 거래적리더십보다 변혁적리더십이 효과적인 것으로 나타났다. The purpose of this study was to explore the effective leadership elements of youth leaders which effect the continuance in activities by youth based on motivation. The subjects were 235 youths affiliated with youth centers in Seoul and Kyong-Gi-Do. Pearson Correlation, Multiple Regression, Path Analysis with SPSSWIN 14.0 and AMOS 4.0 were used for the purposes of data analysis. The results indicated that Laissez-faire leadership had no effect on youth activity motivation and continuance. Transactional leadership had an indirect effect on the continuance of the activity by youth when mediated by extrinsic motivation. However, transformational leadership had an indirect effect on the continuance of the activity by youth when mediated by intrinsic motivation and amotivation. As to the degree of effect on the continuance of the activity by youth, transformational leadership was mere effective than transactional leadership.

고속 전철용 단상 PWM 컨버터의 고조파 저감에 관한 연구

박정배(Jung-Bae Park),임훈규(Hoon-Kyu Lim),이광운(Kwang-Woon Lee),여형기(Hyeong-Gee Yeo),유지윤(Ji-Yoon Yoo) 전력전자학회 1998 전력전자학술대회 논문집 Vol.- No.-

In the high speed rail system, the distortion of the voltage and the current waveform of the input power line, increases the power loss and make a several electro-magnetic problems such as EMI or the interference of the communication line.<br/> In this paper, the control scheme of the PWM converter to make a good power factor and to regulate the output voltage as well as to reduce the harmonic component of the input current is proposed. Also a control schem of the PWM converter in the parallel operation to reduce the harmonics of the input current is proposed<br/>

청소년활동몰입 관련요인에 대한 구조분석

박정배(Park, Jung-Bae),송병국(Song, Byeong-Kug) 한국청소년정책연구원 2011 한국청소년연구 Vol.22 No.4

이 연구의 목적은 청소년활동 진행과정에서 청소년활동 참여자의 청소년활동몰입을 설명하는 종합모델을 구안하고, 청소년활동몰입에 영향을 미치는 관련요인들 간의 구조적 인과관계를 밝히는데 있다. 연구의 목적을 달성하기 위해, 청소년수련시설에서 운영하는 청소년활동에 참여한 460명의 중학생을 대상으로 설문조사를 실시하였다. 배포된 설문지 중 417매가 회수되었으며, 분석에 적합하지 않은 설문지를 제외한 301매가 분석에 이용되었다. 수집된 자료는 AMOS 4.0을 사용하여 공변량구조분석을 실시하였으며, 경로계수의 통계적 유의수준은 5%였다. 연구결과에 따르면 가정환경요인은 자기목적적성격에 직접적인 정적영향(β=.61)을 갖고 있었다. 주관적 안녕감을 유의하게 설명하고 있는 변인은 동료관계(β=.25), 가정환경요인(β=.21) 그리고 지도자관계(β=.14)였으며, 매개변인인 자기목적적 성격은 주관적 안녕감에 유의한 영향을 미치지 못하는 것으로 나타났다. 또한 활동진행내용요인(β=.40), 활동진행방법요인(β=.37), 자기목적적 성격(β=.21), 주관적 안녕감(β=.10)은 청소년활동몰입에 직접효과를 갖는 것으로 나타났으며, 독립변인인 가정환경요인(β=.16), 지도자관계(β=.01), 동료관계(β=.02)는 청소년활동몰입에 유의한 간접효과를 갖는 것으로 나타났다. The purpose of this study is to create and evaluate a structural model through the identification of the cause-and-effect relationships among factors that affect the youth activity flow of participants in youth activity programs. The subjects in this study were 460 middle school students who had participated in a youth activity program managed by a youth center. The reliability and validity of the questionnaire used was proven through a preliminary research Exercise. Out of a total of 460 questionnaires, 417 were collected, invalid or otherwise inappropriate questionnaires were exempted and 301 questionnaires were used in the research. AMOS 4.0 was used to examine the covariance and the level of statistical significance was 5%. The results of this research are as follows. Family environment was found to statistically influence autotelic personality(β=.61). Moreover, a positive relationship with teammates(β=.25), family environment(β=.25), and a positive relationship with one’s leader(β=.14) directly affected subjective well-being. However, the family environment did not directly affect subjective well-being. Additionally, the activity content factor(β=.40), the activity method factor(β=.37), autotelic personality (β=.21) and subjective well-being(β=.10) directly affected the level of the participants’youth activity flow. The factor of family environment (β=.16), autotelic personality (β=.01) and the relationship between leader and teammates (β=.02) indirectly affected the level of the participants’youth activity flow.

CH₄ 제트 화염의 NOx 배출 특성에 관한 수치 및 실험적 연구

박정배(Jung Bae Park),김종현(Jong Hyun Kim),이창언(Chang Eon Lee) 한국연소학회 2000 KOSCOSYMPOSIUM논문집 Vol.- No.-

환경 독성 억제효과를 가진 커큐민 나노스피어가 마우스의 사료 효율 및 악취저감에 미치는 영향

박정배 ( Jeong-bae Park ),이영민 ( Young-min Lee ),박문기 ( Moon-ki Park ),민태선 ( Taesun Min ),이세중 ( Sei-jung Lee ) 한국환경과학회 2019 한국환경과학회지 Vol.28 No.2

Curcumin (C₂₁H₂₀O₆) is a hydrophobic polyphenol found in turmeric. Although curcumin has been used as a natural medicine, its major limitation is related to poor absorption from the gut. Therefore, we developed a method for preparation of Curcumin Nanospheres (CN) to improve the aqueous-phase solubility of curcumin and investigate the functional role of CN in promoting feed efficiency and odor reduction in mice. CN showed inhibitory effects on actate dehydrogenase (LDH) cytotoxicity induced by ecotoxic substance toluene in gut epithelial HCT116 cells. In addition, the weights of internal organs (liver, heart, kidneys, and spleen) and the levels of serum Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT), and LDH did not show significant differences between mice administered oral CN for two weeks and compared to the control group. Interestingly, CN not only reduced hydrogen sulfide (H₂S) and ammonia (NH₃) levels and fecal odor, but also improved feed efficiency in mice. These results demonstrate that oral nano-delivery of anti-ecotoxicological CN is a functional system to deliver curcumin to the gut to improve feed efficiency and reduce fecal odor in mice.

청소년 축구동아리 학생들이 지각하는 스포츠용품 브랜드 구매결정요인이 브랜드자산에 미치는 영향

박정배(Park, Jung-Bae),이태용(Lee, Tae-Yong) 한국사회체육학회 2015 한국사회체육학회지 Vol.0 No.61

The purpose of this study is to seek out the relations between concepts through establishes the relation between the brand equity and the purchase decision factors of sports goods by youth football club students based on theoretical backgrounds and also, to provide basic data that is needed to study on the sports goods consumers. This study represents a population of 373 persons who are selected as the subject for the final analysis of this study, by the convenient sampling method, from football club students in 20 high schools located in B Metropolitan city, U Metropolitan city, or K Prefecture. For processing data, Window SPSS 15.0 statistics package is used as follows, and the significance level of all data analysis is a=.05. Factor analysis, reliability analysis, co-relation analysis, frequency analysis, and multiple regression analysis have been done, and the results of these analyses are as follows: First, among sports goods purchase decision factors, advertisement has a positive effect on the brand loyalty. Second, such factors as quality, brand, and purchase place among sports goods purchase decision factors have a positive effect on the brand image. Third, such factors as quality, brand, and purchase place among sports goods purchase decision factors have a positive effect on the brand awareness.

청소년지도자의 효과적인 리더십 형태의 탐색

박정배 ( Jung Bae Park ),김한별 ( Han Byul Kim ) 한국청소년학회 2006 청소년학연구 Vol.13 No.5-2