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우리나라 접촉 피부염의 역학적 연구 ( 1986 - 1993 ) - 공동연구 -
문기찬(Kee Chan Moon),은희철(Hee Chul Eun),김형옥(Hyung Ok Kim),김계정(Kea Jeung Kim),홍창권(Chang Gwun Hong),이철헌(Cheol Heon Lee),허충림(Choong Rim Haw),함정희(Jeong Hee Hahm),원영호(Young Ho Won),장승호(Seung Ho Chang) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.3
Background : The first multicenter study on standard patenest results(1983-1986) was tried in Korea. Since then 10 years have elapsed and epidemiologi al data need be updated continuously. Objective : To register and compile the results of patch the ig throughout the country and to compare the positivity ard trend with those of previous study. Methods : Standard patch testings were performed using irachamper on Scanpor tape. The results were analysed by a personal computer program. Results : A total of 2326 patch tested cases(male 539, f male 1787) were compiled and analysed. The highest ag distribution was 3rd decade. As the job distribution, housewives and office workers were the mast frequent consisting 33.4% and 12.1% respectively. The face was the most frequently affected site comprising 49.6%. The highesteritization rates were foud with nickel(17.9%), cobalt(13.8%), fragrance mix(12.9%), potass ur dichromate(11.3%), ammoniated mercury(8.7%), neoaycin(7.2%). The lowest positivity inclured black rubber mix(1.0%), primin (1.2%), ethylenediarnine(1.3%), carba mix(1.4%), While nicel epoxy resin and 4-t-butylphenol formaldehyde resin showed increased reactivities, PPD, bacrubber mix, balsam of Peru, quaternium 15, ammceniatct mercury and captan showd a deceased tendency when compared with those of previous study. Conclusion : The large scale studies of epidemiology in cortat dermatitis have been performed and they need to be updated and analysed consecutively in the future. (Kor J Dermatol 1995;33(3): 445-452)
문기찬(Kee Chan Moon),김수남(Soo Nam Kim),김종일(Jong Il Kim),김창규(Chang Kew Kim) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.5
This study was undertaken to investigate some mechanical properties of the skin with special relatio to pH. The abdomenal skin of guinea pig was prepared and cut into appropriate skin strips(1.5mm*15mm). The pieces of skin strips were then suvject to measurement (stretching and vreaking load) using a rheometer after treatment in various pH vuffers and humectant solutions (lactic acid, PCA, citric acid). The result are summarized as follows ; 1. Treatment of the skin in the extreme acidic (pH3) solution showed significant deformity (swelling and shrinkage in length). 2. The overall measurements after treatment in the humectant solutions were not significantly different from those in standard vuffer solutions. 3. The stretching was maxiaml at pH7 and minimal in the extreme ranges of pH(pH 3 and pH11). 4. The measurement of vreaking load showed minimal value at acidic pH3 and revealed linear increments as pH increased.
CambisonR 안연고에 의한 알레르기성 접촉 피부염
장경애,최지호,문기찬 ( Kyung Ae Jang,Jee Ho Choi,Kee Chan Moon ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
Cambison ophthalmic ointment is an easily available topical medicament in Korea, However, the allergic contact dermatitis lo Cambison ophthalmic ointment has not been reported in Korean dermatology literature. We report, a case of allergic contact dermatitis in a 28-year-old female who suffered from itchy, erythematous patches on both periorbital areas. She wore contact lenses and for the last year, she hac applied Cambison ophthalmic ointment to both periorbital areas. The skin lesions were aggravated gradually. A patch test showed positive reactions to Cambison ophthalmic ointment, neomycin, mercury and thimerosal. We suspect neomycin contained in Cambison ophthalmic ointment to be the etiologic agent. When contact dermatitis occurs on periorbital areas, topical ophthalmic ointment or lens cleaner may be considered as a causative agent. (Kor J Dermatol 1997;36(2): 368-361)
Pruritic Urticarial papules and Plaques of Pregnancy ( PUPPP ) 3예
홍진호(Jin Ho Hong),문기찬(Kee Chan Moon) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.5
We roport herein three cases of pruritic urticarial papules and plaques of pregnancy in two primigravidas and one multigravida in erythematous papules and urticarial plaques on both thighs, buttock and upper extremites. In the second case, lesions initially developed on both thighs and then preaded on abdomen, back and exter ities. Abdomen, thighs and extremites were involved in the third case. Histopathologic findings revealed acanthosis orfocal spongiosis in epidermis and lymphocytic perivascular infiltration with or without eosinophilsn dermis. They were treated with systemiror topical steroids and, mtihistamines. Itching was relieved within a few days after therapy and skin lesions resolved spontaneously after delivery. (Kor J Dermatol 1992;30(5):659-664)
장경애,최지호,성경제,문기찬,고재경 ( Kyoung Ae Jang,Jee Ho Choi,Kyung Jeh Sung,Kee Chan Moon,Jai Kyoung Koh ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
We report a case of histiocytoid hemangioma(angiolymphoid hyperplasia with eosinophilia) in a 60 year-old female patient who was effectively treated with dapsone. The therapeutic effect of dapsone may support the hypothesis that immunologically mediated reactive process plays a role in the pathogenesis of histiocytoid hemangioma. (Kor J Dermatol 1997;35(2): 350-353)
문혜림 ( Hye Rim Moon ),원광희 ( Kwang Hee Won ),윤우진 ( Woo Jin Yun ),원종현 ( Chong Hyun Won ),장성은 ( Sungeun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),문기찬 ( Kee Chan Moon ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.3
Fixed drug eruption is a pattern of a drug-induced cutaneous reaction. It is characterized by skin erythematous plaques that recur at the same site each time the drug is administered. Now, we report the case of a 26-year-old woman who presented with 2 ill-defined erythematous patches on her back with itching sensation. The patient had a history of ciprofloxacin medication. The patch test with suspected drugs showed negative reactions, but intradermal tests were positive reactions. The patient was diagnosed with fixed-drug eruption due to ciprofloxacin. (Korean J Dermatol 2013;51(3):192∼195)
박현철(Hyun Chul Park),문기찬(Kee Chan Moon),김수남(Soo Nam Kim) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.5
A 21-year-old male suffered from generalized anhidrosis and heat intolerance for about 15 years. Other clinical features included multiple angiokeratoma on the back, scrotum and extremities, together with ocular involvement. The electronmicroscopic studies of the skin demonstrated laminated intracytoplamic inclusions in the endothelial cells, pericytes of dermal vessels, fibroblasts and eccrine glandular cells. a Galactosidase assay of leukocytes from the patient and his uncle showed nearly absence of the activity,
김일환(Il Hwan Kim),문기찬(Kee Chan Moon),김수남(Soo Nam Kim) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.5
We report a case of toxic shock syndrome in 17-year-old female patient with skin abscess. She had a skin abscess on left inner thigh about 6th days ago, but no treatment was done. And then she presented with the features of high fever, hypotension, generalized rash, myalgia and diarrhea. After the treatment with anti-shock rneasures, skin wound dressing and systemic antibiotics adminstration, she was completely recovered with generalized desquamation on 10th hospital day.
홍승민(Seung Min Hong),문기찬(Kee Chan Moon) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.5
A case of cutaneous cartilaginous tumor was diagnosed from solitary nadular skin lesion on a toe of 59-year old female. Lack of information about cartilage tumors in the dermatologic literature suggest that they rarely develop as supeficial lesions. General clinico-pathologic feature of the tumor is reviewed.