특발성 황반 원공에 대한 수술적 치료 후 2년 경과관찰

노영정 ( Young Jung Roh ),김도현 ( Do Hyun Kim ),유진성 ( Jin Seong Yoo ) 대한안과학회 2003 대한안과학회지 Vol.44 No.1

LASIK 수술에서 각막절편의 크기에 따른 임상결과 비교

노영정 ( Young Jung Roh ),주천기 ( Choun Ki Joo ),김재호 ( Jae Ho Kim ) 대한안과학회 2002 대한안과학회지 Vol.43 No.5

유리체내 트리암시놀론 주입 전 스테로이드 점안 선별검사의 유용성

노영정,김웅재,문정일.Young-Jung Roh. M.D.. Wung-Jae Kim. M.D.. Jung-Il Moon. M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.12

Purpose: To evaluate the efficacy of screening of high risk groups with topical steroids due to increased ocular pressure by intravitreal triamocinolone injection (IVTA). Methods: We selected 96 eyes that had undergone IVTA between January 2003 and December 2004. The screening method used was as follows; We administered 4 drops daily of prednisolone (1%) eye drops for 3weeks and included patients with an intraocular pressure increase of less than 5 mmHg for the procedure. Two groups consisting of the post-screening IVTA group (group A) and non-screening group (group B) were classified, and intraocular pressure was measured using a Goldman applanation tonometer at 1 week, 1 month, 2 months, 3 months and 6 months after the procedure. Results: One patient in group A (3.1%) required glaucoma medication compared with 10 patients in group B (17.9%), and one of these group B patients required surgical intervention. Chi-square analysis showed a statistically significant reduction in glaucoma medication use in group A compared with group B (P<0.05). Group B had a higher percentage of patients with an increase of intraocular pressure over 5 mmHg compared with values before the procedure, particularly in the second and third months after the procedure. Conclusions: IVTA after screening resulted in less use of glaucoma medication and a reduced rate of increase in intraocular pressure. Complications due to increased intraocular pressure by IVTA can be minimized by screening high risk groups.

난치성 포도막염에서 종양괴사인자항체의 치료효과

최석규,노영정,김민호,Suk Kyue Choi,Young Jung Roh,Min Ho Kim 대한안과학회 2007 대한안과학회지 Vol.48 No.2

Purpose: To investigate the effects of Anti-TNF-α (infliximab, Remicade?, Shering-Plough) on refractory uveitis. Methods: A retrospective observational survey was conducted on 12 eyes of 10 patients with refractory uveitis. These patients had no response to immunosuppresants or systemic steroid therapy and were intolerable due to drug toxicity. After an intravenous injection of Anti-TNF-α, best corrected visulal acuity was measured. Improvement in inflammation was then observed at the first, third and last month of follow-up. Results: Patients were observed for a mean period of 15 months. They received anti-TNF-α intravenously, ranging from one to eleven infusions. After infusion with Anti-TNF-α, remission of intraocular inflammation was evident in all patients within 9.7 days. Best corrected visual acuity also improved at the first, third, and last month of follow-up. Two patients were infected by tuberculosis and mumps respectively. Conclusions: There was an effect on refractory uveitis with anti-TNF-α therapy. Many participants may also require further evaluation after treatment.

Nd:YAG 레이저 후낭절개술 후 발생한 황반원공 1예

김인태,노영정,In Tae Kim,Young Jung Roh 대한안과학회 2008 대한안과학회지 Vol.49 No.4

Purpose: To report a case of a macular hole resulting from accidental Nd:YAG laser capsulotomy for cataract, which was treated by vitrectomy. Case summary: A 70-year-old man had decreased visual acuity one day after Nd:YAG laser capsulotomy. By fundus exam, vitreous and macular hemorrhages were observed. After 11 days, intravitreal gas injection was performed, and 3 months later, a macular hole has developed. Pars plana vitrectomy, internal limiting membrane peeling, and gas tamponade were performed, and anatomical occlusion was achieved and maintained for 6 months postoperatively. However, final visual acuity improvement was limited up to 0.08. Conclusions: We experienced an unusual case of macular hole formation from Nd:YAG capsulotomy. Vitrectomy was performed but visual acuity improvement remained limited.

한국인 고혈압 환자에서 고혈압망막병증과 표적기관장애의 동반양상

강승범,노영정,문정일,Seungbum Kang,Young-Jung Roh,Jung-Il Moon 대한안과학회 2010 대한안과학회지 Vol.51 No.9

Purpose: To report the relationship between hypertensive retinopathy and associated target organ damage in Korean hypertensive patients. Methods: A total of 519 hypertensive patients were divided into hypertension retinopathy grades I through IV based on fundus examination. According to the grade of each hypertensive retinopathy, the frequency of target organ damage (cardiovascular disease, chronic kidney disease, and retinal vessel occlusion) and the association with hypertension retinopathy were evaluated. Results: There were 211 patients (40.7%) without hypertensive retinopathy, 226 patients (43.5%) with hypertensive retinopathy grade I, 71 patients (13.7%) with grade II, seven patients (1.3%) with grade III and four patients (0.8%) with grade IV. The numbers of patients with cardiovascular disease were 103 (45.6%) in grade I, 57 (80.3%) in grade II, 3 (42.9%) in grade III, two (50.0%) in grade IV, and 70 (37.4%) in the non-hypertensive retinopathy group. According to four grades, the numbers of patients with cerebrovascular disease were three (1.3%), two (2.8%), zero (0%), and one (25.0%), respectively, with two (0.9%) in the non-hypertensive retinopathy patients. The respective numbers of patients with chronic kidney according to grades I through IV were 14 (6.2%), ten (14.0%), two (28.6%), and four (100.0%), as well as ten (4.7%) in the non-hypertensive retinopathy patients. The respective numbers of patients with retinal vessel occlusion were one (0.4%), two (2.8%), one (14.3%), and one (25.0%), with zero (0%) in the non-hypertensive retinopathy patients. Conclusions: The significance of hypertensive retinopathy should not be overlooked in Korean hypertensive patients due to an association with various target organ damage. J Korean Ophthalmol Soc 2010;51(9):1231-1236

불응성 포도막염에 대한 유리체내 트리암시놀론 주입효과

최석규,노영정,김민호,Suk Kyue Choi,Young Jung Roh,Min Ho Kim 대한안과학회 2006 대한안과학회지 Vol.47 No.3

Purpose: To investigate the effect of intravitreal injection of triamcinolone acetonide (4 mg) on refractory uveitis with cystoid macular edema (CME). Methods: A retrospective observation survey was conducted on 21 eyes of 15 patients with refractory uveitis that had no response to immunosuppresants or systemic steroid therapy. Seven eyes were injected with triamcinolone acetonide intravitreally only, and fourteen eyes were injected during pars plana vitrectomy. At 3 and 12 months after triamcinolone acetonide injection, best corrected visual acuity and thickness of macula were measured by OCT. Results: The average pre-treatment best corrected visual acuity was 0.18±0.08, and the average macular thickness was 534±132 ?m. At 3 months after injection, the results for the same parameters were 0.45±0.18, 345±125 ?m respectively. At 12 months after injection, they were 0.30±0.09, 498±133 ?m respectively. Thus, best corrected visual acuity had improved and macular thickness had decreased at 3 months post-injection for the groups with intravitreal injection of triamcinolone acetonide and intravitreal injection during pars plana vitrectomy. However, these changes in best corrected visual acuity and macular thickness were not observed 12 months after injection. Conclusions: Intravitreal injection of triamcinolone acetonide had a temporary effect on refractory uveitis with cystoid macular edema (CME). However, a study that includes more participants will be necessary for conclusive evaluation.

한국인의 특발성 망막앞막에서 투명각막절개 초음파유화술과 유리체절제술의 병합 및 연속수술

정경인,송민혜,노영정,Kyoung In Jung,Min Hye Song,Young Jung Roh 대한안과학회 2011 대한안과학회지 Vol.52 No.2

Purpose: To evaluate the surgical outcomes on the combined procedures of phacoemulsification, intraocular lens (IOL) implantation, and vitrectomy, and to compare clinical results with sequential surgery results in Korean patients with idiopathic epiretinal membrane. Methods: The present retrospective study included 20 eyes of 19 patients with idiopathic epiretinal membrane who underwent combined phacoemulsification, IOL implantation, and pars plana vitrectomy (combined surgery), and 18 eyes of 18 patients who underwent phacoemulsification and IOL implantation subsequent to vitrectomy (sequential surgery). Postoperative clinical results and intra- and postoperative complications were compared between the 2 groups. Results: Postoperative best corrected visual acuity (BCVA) (logMAR) was 0.41 ± 0.42 in the combined group, and 0.35 ± 0.37 in the sequential group. There was no significant difference in BCVA between the 2 groups (p = 0.675). The mean refractive prediction error was -0.46 ± 0.88 diopters (D) in the combined group, and -0.06 ± 0.68 D in the sequential group, showing no statistically significant difference between the 2 groups (p = 0.147). The present study showed no major differences between the 2 groups in complications such as intraoperative mild corneal edema, postoperative ocular hypertension, and lens capsular opacity. Conclusions: Combined phacoemulsification, IOL implantation, and pars plana vitrectomy as well as the two-step procedure are safe and effective for treating patients with idiopathic epiretinal membrane. J Korean Ophthalmol Soc 2011;52(2):203-209

VKH 증후군과 유사한 양안 다발성 장액성 망막박리를 보인 양측성 부신 림프종

김인태,박혜영,노영정,In Tae Kim,Hae Young Park,Young Jung Roh 대한안과학회 2008 대한안과학회지 Vol.49 No.7

Purpose: To report a case of bilateral adrenal gland lymphoma mimicking symptoms of Vogt-Koyanagi- Harada syndrome. Case summary: A 57-year-old woman complained of decreased visual acuity and metamorphopsia in both eyes. She had no prior medical history, but had experienced headaches in the past week. Fundus examination revealed multiple serous retinal detachment. Fluorescein angiography of the fundus revealed multiple pinpoint leaks in early stages and subretinal dye pooling in the retinal detachment area in late stages. The most likely diagnosis was therefore Vogt-Koyanagi-Harada syndrome. Two days later, mild fever developed and a systemic evaluation was performed. Computed tomography of chest and abdomen showed bilateral adrenal gland T-cell lymphoma. Through prompt combination chemotherapy, the patient’s systemic condition recovered, and her fundus recovered with improved visual acuity. Conclusions: We experienced a rare case of bilateral adrenal lymphoma which masqueraded as Vogt-Koyanagi- Harada syndrome. When there are systemic symptoms such as mild fever and headaches, systemic evaluation should be done so as not to miss more serious systemic pathology. J Korean Ophthalmol Soc 49(7):1198-1202, 2008

실리콘이 충전된 눈에서 부분결합간섭계를 이용한 인공수정체 도수계산

강승범(Seungbum Kang),노영정(Young Jung Roh) 대한검안학회 2012 Annals of optometry and contact lens Vol.11 No.1

목적: 실리콘이 충전된 눈에서 부분결합간섭계를 이용한 인공수정체 도수결정의 정확성을 알아보고자 하였다. 대상과 방법: 실험군은 실리콘이 충전된 눈에서 부분결합간섭계를 이용하여 인공수정체 도수를 정하고 실리콘기름 제거술과 인공수정체 삽입술을 동시에 시행한 10안을 대상으로 하였다. 대조군은 실리콘 기름을 제거한 후 초음파를 이용한 A-scan (Tomey, Nagoya, Japan)으로 인공수정체의 도수를 계산하고 단계적으로 인공 수정체를 삽입한 12안을 대상으로 하였다. 술 후 3개월째 실제 굴절값을 측정하였고, 목표 굴절값과 차이인 굴절예측이상값을 구하여 두 군의 굴절예측이상값의 평균을 비교하였다. 결과: 실험군의 술 후 3개월째 실제 굴절값의 평균은 -1.30±1.57디옵터였고 굴절예측이상값의 평균은 -0.08±1.04디옵터였다. 대조군의 술 후 3개월째 실제 굴절값이 평균은 -1.63±1.75디옵터였고, 굴절예측이상값의 평균은 -0.48±1.27디옵터였다. 두 군의 굴절예측이상값 사이의 평균은 통계적으로 유의하지 않았다(p=0.674). 결론: 부분결합간섭계는 실리콘이 충전된 눈에서 인공수정체 도수를 결정할 경우 유용하게 사용될 수 있다. Purpose: To evaluate the accuracy of intraocular lens (IOL) power calculation in eyes that have been operated on by silicone oil removal combined with IOL implantation using partial coherence interferometry. Methods: 10 eyes of 10 patients with silicone oil tamponade were included in this study. The IOL power calculation for 10 eyes was performed using partial coherence interferometry. 12 eyes of 12 patients with silicone oil tamponade were also included in this study as control group. 12 eyes in control group had IOL implantation after silicone oil removal. The IOL power calculation for control group was performed using conventional ultrasound A-scan (Tomey, Nagoya, Japan). Three months after silicone oil removal combined with IOL implantation, actual refraction was measured. To compare the difference between the actual and target refraction, refractive prediction error was calculated. It is defined as substraction of target refraction from actual refraction. Results: At three months, actual refraction and refractive prediction error of the group using partial coherence interferometry were -1.30±1.57 diopter and -0.08±1.04 diopter, respectively. At three months, actual refraction and refractive prediction error of the control group using ultrasound A-scan were -1.63±1.75 diopter and -0.48±1.27 diopter, respectively. There was no statistically significant difference between two values (p=0.674). Conclusions: Partial coherence interferometry seems to be satisfactory accurate method to calculate IOL power in silicone oil-filled eye.