버섯복합물의 항산화 효과

전동하(Dong Ha Jun),김희영(Hui Yeoug Kim),한상익(Sang Ik Han),김영훈(Young Hun Kim),김세기(Se Gie Kim),이진태(Jin Tae Lee) 한국생명과학회 2013 생명과학회지 Vol.23 No.3

이 연구에서는 동충하초, 영지, 상황 버섯 복합물의 항산화 효과를 평가하였다. 3가지 버섯을 각각 70% 에탄올 추출하여 80:10:10의 비율로 혼합하여 평가를 실시하였다. DPPH radical을 이용한 전자공여능 측정에서는 버섯 복합물이 500 μg/ml의 농도에서 66%의 효과를 나타내었고, ABTS radical cation decolorization 측정은 50 μg/ml에서 73%, 500 μg/ml에서 대조군인 BHA와 유사한 효과를 나타내었다. Superoxide anion radical 소거능 측정은 버섯 복합물 10 μg/ml에서 41%로 대조군인 BHA에 비해 3배 이상의 높은 효과가 있었고, 50 μg/ml, 100 μg/ml에서도 BHA 보다 효과가 높았으나, 500 μg/ml에서는 낮은 효과를 나타내었다. Lipid oxidation 측정 결과 Cu<SUP>2+</SUP>군보다 Fe<SUP>2+</SUP>군이 지방 산패 억제능이 뛰어났다. SOD 유사활성능 측정은 500 μg/ml에서 13%의 낮은 효과를 나타내었다. 이 결과, 버섯 복합물의 항산화 효과가 아주 우수했으므로, 항산화 소재로서의 가능성을 확인할 수 있었다. In this study, we evaluated the antioxidant effects of Cordyceps, Ganoderma lucidum (Curtis) P. Karst and Phellinus linteus complexes. Three mushrooms were extracted using 70% ethanol, respectively, in ratios of 80:10:10(?). The electron-donating ability was measured using the DPPH radical mushroom complexes and showed effects of 66% in 500 μg/ml. ABTS radical cation decolorization measured 73% in 50 μg/ml and had an effect similar to BHA in 500 μg/ml. In their superoxide anion radical scavenging ability, the mushroom complexes showed an effect of 41% in 10 μg/ml. The effect on the control of BHA was more than three times as high as BHA in 50 μg/ml and 100 μg/ml concentration. The results showed that lipid oxidation is an excellent inhibitor of lipid oxidation Cu<SUP>2+</SUP>, compared to the Fe<SUP>2+</SUP> group. The results of superoxide dismutase (SOD) activity in the mushroom complexes showed a low effect of 13% in 500 μg/ml. Thus, the results of this study showed that the antioxidant effect of the mushroom complexes was excellent, indicating their potential as an antioxidant material.

에볼라 바이러스 감염의 전신 및 구강내 소견

김민지(Min Ji Kim),김희영(Hui Young Kim),김성민(Soung Min Kim),명훈(Hoon Myoung),이종호(Jong Ho Lee) 대한치과의사협회 2016 대한치과의사협회지 Vol.54 No.1

Ebola virus disease is a lethal viral hemorrhagic fever that has been boiling in sub-Saharan Africa since 1970s. Last year, The Ebola virus epidemic that has spread not only mainly in West Africa, but also in locals such as USA, Europe and the Antipodes via infected travelers, was brought up. Human-to-human transmission of Ebola virus disease is known only through direct contact with the blood, secretions, tissues or other bodily fluids, including saliva. Although there has not been reported infection cases in the dental healthcare settings, the fact that the infection of the Ebola virus may be made from human secretions such as saliva suggests that there is a high risk of infection for the Ebola virus of dental healthcare workers. Therefore, it is important dental healthcare workers to identify infection-suspected patients through the oral findings for infection prevention. This article will review the oral signs and symptoms of Ebola virus disease and discuss the pathogenesis, treatment and prevention. Furthermore, Infection control guidelines for oral healthcare workers are also proposed.

단기 기억력에 대한 자침의 효과

이봉효 ( Bong Hyo Lee ),김희영 ( Hee Young Kim ),박지하 ( Ji Ha Park ),양태영 ( Tae Young Yang ),장은영 ( Eun Young Jang ),전호성 ( Ho Seong Jeon ),추희영 ( Hui Yeong Chu ) 대구한의대학교 제한동의학술원 2015 東西醫學 Vol.40 No.3

Objectives:This study was performed to know whether acupuncture on acupoints GB20, GV20-GV21-GV22, Tonifying Pericardium Meridian, BL10, ST4 that are known to calm spirit and used frequently in clinic could be effective on improvement of short term memory. Materials & Methods:29 adults were subjected to Digit span test, Wechsler Adult Intelligence Scale test, and Nonsense syllable test. Subjects were assigned to control group and the five acupuncture groups randomly. Results:In the Digit span test, GV20-GV21-GV22, Tonifying Pericardium Meridian, BL10, and ST4 groups have shown significant predominance compared to the control group;while in the nonsense syllable test, GB20 exerted significant effect compared to the control group. However, in the Wechsler Adult Intelligence Scale test, there was no significant difference. Conclusions:Results of this study suggest that GB20, GV20-GV21-GV22, Tonifying Pericardium Meridian, BL10, ST4 acupunctures may be an effective treatment for the improvement of short term memory. However, the difference of effectiveness should be considered in the clinical treatment.

율피추출물의 사람 비만세포주 사이토카인 발현 억제 효과

전동하 ( Dong Ha Jun ),장영아 ( Young Ah Jang ),김희영 ( Hui Yeong Kim ),김수진 ( Su Jin Kim ),김진철 ( Jin Chul Kim ),김세현 ( Sea Hyun Kim ),권대준 ( Dae Jun Kwoen ),한상익 ( Sang Ik Han ),이진태 ( Jin Tae Lee ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.2

Objectives: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczematous inflammtion of the skin. The chestnut inner shell extracts (CI) has been used as a cosmetic material for a long time in Korea. However, the precise anti-allergy effects of CI have yet to be clearly elucidated. In this study, we attempted to evaluate the effect of CI on mast cell-mediated allergy inflammation. Methods: To find the anti-allergy and inflammatory effect of CI, we investigated the inhibitory effect of CI on the production of inflammatory mediators using by enzyme-linked immunosorbent assay in phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore (A23187) stimulated-human mast cell (HMC-1). Results : In this study, we found that CI did not show cytotoxic effect at up to 10 ug/ml on HMC-1. CI inhibited the production of tumor necrosis factor (TNF)-a, interleukin (IL)-6 and IL-8 in stimulated HMC-1. Maximal rate of TNF-a, IL-6 and IL-8 inhibition by CI (10 ug/ml) were about 47.6%, 44.1% and 22.5% respectively. In addition, we showed that Fr.3 isolated from n-Butyl alcohol layer of CI attenuated the production of TNF-a, IL-6 and IL-8 in HMC-1. Conclusion: Taken together, the findings of this study provide us with a novel insight action of CI as a potential molecule for use in the treatment of allergic inflammation diseases.

C-밴드 완전 편파 측정용 스캐터미터 시스템 보정 기술 검증

박신명(Sin-Myeong Park),고주석(Joo-Seoc Go),주정명(Jeong-Myeong Joo),김희영(Hee-Young Kim),김주희(Ju-Hui Kim),황지환(Ji-Hwan Hwang),권순구(Soon-Gu Kwon),신종철(Jong-Chul Shin),오이석(Yisok Oh) 한국전자파학회 2012 한국전자파학회논문지 Vol.23 No.10

본 논문에서는 미소 뮬러 행렬 보정법(differential Mueller matrix calibration technique: DMMCT)을 이용하여 C-밴드의 지상운용용 HPS(Hongik Polarimetric Scatterometer) 시스템을 보정한 연구 결과를 선보인다. 스캐터미터 시스템 보정을 위해 금속구를 이용하여 안테나 주빔에서의 편파 측정한 안테나 패턴을 챔버에서 측정하고, DMMCT를 이용하여 지상운용용 HPS의 왜곡 정도를 분석하여 정확하게 보정한다. 단일 편파 시스템과는 다르게 완전 편파 시스템에서는 후방 산란 계수뿐만 아니라 위상 변수들도 중요하다. 보정된 지상운용용 HPS를 이용하면 논, 맨땅, 작물밭 등의 지표면에 대한 정확한 Mueller 행렬을 얻을 수 있으므로, 후방 산란 계수뿐만 아니라 동일 편파와 교차 편파의 위상 변수들도 정확하게 측정하게 된다. 보정의 정확도는 산란 모델을 이용해 계산한 후방 산란 계수와 측정한 후방 산란 계수의 비교로 확인할 수 있다. 따라서 측정으로 쟁기질 한 밭의 편파 응답특성을 얻었으며, 이 결과를 이론 모델로 얻은 편파 응답 특성과 비교하여 보정 기술을 검증하였다. This paper presents a study on the calibration of a C-band HPS(Hongik Polarimetric Scatterometer) system using the DMMCT(Differential Mueller Matrix Calibration Technique). For calibration of the polarimetric scatterometer system, a fully-polarimetric antenna pattern(magnitudes and phase-differences) of the antenna main-beam is measured using a conducting sphere at anechoic chamber. The polarimetric scatterometer system could be accurately calibrated after retrieving its distortions using the DMMCT. Unlike a single-polarimetric system, in a fully-polarimetric system, not only backscattering coefficients but also phase differences are important parameters. This calibrated HPS system can be used to measure accurate Mueller matrices of bare soil surfaces, rice paddies, and vegetation fields. The phase-difference parameters as well as the backscattering coefficients for co- and cross-polarizations can then be obtained. The accuracy of calibration was verified by comparing the measured backscattering coefficients with a scattering model. The measured polarization response of a plowed bare field was also compared with the polarization response which was synthesized using a polarimetric scattering model for verifying the calibration technique.