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고삼이 항암제 cisplatin의 췌$\cdot$심장 부작용 감소에 미치는 영향
김진철,임성철,정태영,서정철,한상원,Kim, Jin-Cheo,Lim, Seong-Chul,Jung, Tae-Young,Seo, Jung-Chul,Han, Sang-Won 대한동의생리학회 2005 동의생리병리학회지 Vol.19 No.3
The objective of this study is to investigate the inhibitor effects of an traditional oriental herb, Sophora flavescens on the pancreatic & cardiac side effects of chemotherapy were studied by using Bl6-BL6 melanoma-injected C57BL6 mouse tumor model. In this study, the effects of an traditional oriental herb, Sophora flavescens, on the side effects of chemotherapy were studied using B16 melanoma-injected C57BL6 mouse tumor model. Anticancer drugs widely used in clinical situation. Sophora flavescen has significant effect on the reduction of the side effects of chemotherapy. Water extract of Sophora flavescens significantly inhibited cisplatin-induced increase of amylase (AMY) which is a good indicator of pancreatic toxicity. Sophora flavescens extract does not decrease the anti-tumor activity of cisplatin showing that it can selectively inhibit side effects of anticancer drugs preserving beneficial effect. Theses results suggest a possibility that Sophora flavescens extract can be used for cancer patients for the reduction of the side effects and improving the quality of life during chemotherapy of cancer patients.
모바일 인터넷 전화 서비스의 예방적 서비스 품질 관리 체계 구축을 위한 품질 측정 소프트웨어 개발 및 신뢰성 검증
김진철,김범준,Kim, Chin-Chol,Kim, Beom-Joon 한국정보처리학회 2011 정보처리학회논문지 C : 정보통신,정보보안 Vol.18 No.2
스마트폰의 등장으로 모바일 인터넷 전화 서비스의 보급이 활발하게 이루어지고 있는데 반하여 이의 품질 관리 체계에 대한 대비는 상대적으로 미흡한 상황이다. 향후 모바일 인터넷 전화 서비스가 성공적으로 정착되어 활성화되기 위해서는 철저한 품질 관리가 요구되는데 전통적인 계측기를 이용하는 방법으로는 실시간 모니터링이 불가능함으로 인한 여러 가지 한계점이 발생할 수 있다. 따라서 본 논문에서는 모바일 인터넷 전화의 예방적인 서비스 품질 관리 체계를 제안하고 이의 구현을 위한 소프트웨어를 개발하였다. 상용 소프트웨어와의 비교를 통한 개발된 소프트웨어의 검증을 위한 시험 절차가 진행되었고 시험 결과 개발된 소프트웨어의 측정 결과가 상당히 신뢰할 수 있음을 확인하였다. Although a mobile Internet telephony service becomes popular with the rapid propagation of smart phones, its service quality management system has not been prepared enough yet. For successful settlement and deployment of the mobile Internet telephony service in future, a strict service quality management is required. The service quality management using a specific measurement equipment has limitations that real-time monitoring is impossible. In this paper, therefore, we propose a proactive service quality management system for the mobile Internet telephony service and develop a software for its implementation. The developed software is verified by comparing the measurement results from the developed software to those from the softwares commonly used, and it is proved that the developed software is quite reliable.
라식 수술 후 압평안압계와 비접촉성 안압계 측정치간 큰 차이를 보인 1예
김진철,정태영,기창원.Jin Chul Kim. M.D.. Tae Young Chung. M.D.. Chang Won Kee. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.6
Purpose: To report the case of a glaucoma patient with a history of LASIK surgery who presented with a wide discrepancy in intraocular pressure between the Goldmann applanation tonometry and non-contact tonometry. Methods: A 20-year-old male glaucoma patient was referred to our clinic with a chief complaint of blurred vision in his right eye. The patient had a history of uneventful bilateral LASIK surgery. Upon our initial examination, his best-corrected visual acuity in the right eye was 0.04 and his right eye IOP was 14 mmHg by Goldmann applanation tonometry and 40 mmHg by non-contact tonometry. A slit lamp examination showed corneal epithelial edema with diffuse interface opacities. The central corneal thickness in the right eye was 587 ?m. An ultrabiomicroscopy demonstrated an interface fluid accumulation between the LASIK flap and the stromal bed. The patient was diagnosed with juvenile open-angle glaucoma and was scheduled for a trabeculectomy. Results: Seven days after trabeculectomy, the patient`s vision in the right eye improved to 0.7 and his IOP was 12 mmHg by Goldmann applanation tonometry and 14 mmHg by non-contact tonometry. In addition, the corneal epithelial edema, interface opacities, and fluids had all resolved and the central corneal thickness was reduced to 489 ?m. Conclusions: In eyes that have undergone LASIK surgery, the IOP measured by Goldmann applanation tonometry may underestimate the true pressure due to fluid accumulation under the LASIK flap. In such cases, non-contact tonometry can be a convenient and a reliable method for determining treatment plan.