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치성상피종양으로부터 상악에 발생한 치성유령세포암종의 치험례
김진학(Jin-Hak Kim),김문기(Moon-Key Kim),차인호(In-Ho Cha),김진(Jin Kim),김현실(Hyun-Sil Kim),최희수(Hee-Soo Choi),김형준(Hyung-Jun Kim) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.3
The neoplastic variant of calcifying odontogenic cyst has various designation, and its malignant counterpart has been reported as aggressive epithelial ghost cell tumor or odontogenic ghost cell carcinoma. Odontogenic ghost cell carcinoma(OGCC) is a rare carcinoma first documented in 1985. It is composed of varying sized islands of anucleated cells with homogenous, pale eosinophilic cytoplasm, so called ghost cells, were admixed with nucleated cells. We report a case of maxillary OGCC developed from odontogenic epithelial tumor in a 25-year-old man with literature review.
꽈배기 모자반 물 추출물의 항산화능과 물리적 특성에 대한 감마선 조사의 영향
김아람(Ah-Ram Kim),송유진(Eu-Jin Song),김미정(Mi-Jung Kim),이소영(So-Young Lee),김꽃봉우리(Koth-Bong-Woo-Ri Kim),김진희(Jin-Hee Kim),김서진(Seo-Jin Kim),홍용기(Yong-Ki Hong),박진규(Jin-Gyu Park),김재훈(Jae-Hun Kim),이주운(Ju-Woon Lee) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.3
본 연구에서는 꽈배기모자반 물 추출물에 식품산업에서 사용이 확대되고 있는 감마선 조사기술을 이용하여 항산화능의 변화를 알아보고, 꽈배기모자반 물 추출물의 높은 점성과 짙은 색상으로 인한 문제점을 개선하고자 하였다. 꽈배기모자반 물 추출물의 감마선 조사에 따른 항산화능의 변화를 알아보기 위해 총 페놀화합물 함량을 측정하고 DPPH radical 소거능을 측정하였다. 그 결과, 3~20 kGy의 감마선을 조사한 꽈배기모자반 물 추출물은 조사선량이 증가할수록 총 페놀화합물 함량이 증가하였고, DPPH radical 소거능도 증가하여 감마선 조사에 의해 항산화능이 증진되었다. 그리고 꽈배기모자반 물 추출물에 감마선 조사 시 물리적 특성 변화를 알아보기 위해 색상과 점도를 측정한 결과, 감마선 조사선량이 증가할수록 색이 옅어지고 점성이 감소하는 것으로 나타났다. 이를 통해 꽈배기모자반 물 추출물에 감마선을 조사한 후 식품에 적용 시 가공특성을 개선시킬 수 있을 것으로 사료된다. 따라서 감마선 조사는 꽈배기모자반 물 추출물의 물리적 특성을 개선시키고 항산화능 또한 증진시키므로 식품산업에 적용 시 기존의 천연 항산화제의 단점을 개선시킬 수 있는 기술로서 사용이 확대될 수 있을 것으로 사료된다. In this study, the antioxidant properties and physical characteristics of irradiated Sargassum siliquastrum water extract were evaluated. Samples were irradiated with Co<SUP>60</SUP> γ-ray at doses ranging from 3 to 20 kGy. They were then analyzed to investigate antioxidant properties, including total phenolic compound content and DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. In addition, physical properties such as viscosity and color were evaluated. The results demonstrated that total phenolic compound content and DPPH radical scavenging activity were significantly improved (p<0.05) by irradiation. In terms of physical properties, viscosity and color were reduced in the irradiated extracts as compared to non-irradiated samples. In conclusion, gamma irradiation improved the antioxidant properties of Sargassum siliquastrum water extract, improving its original weak point as a natural antioxidant when applied in the food industry.
김진동(Jin-Dong Kim),차종호(Jong-Ho Cha) 한국산학기술학회 2017 한국산학기술학회논문지 Vol.18 No.12
세월호 사고는 우리나라 정치, 경제, 사회 등 다양한 분야에 지금까지 영향을 미치고 있으며, 세월호 사고를 계기로 안전에 대한 국민의 의식이 강화되고 있다. 따라서 본 연구는 세월호 사고 이전연도와 이후연도 간에 소방서비스 환경의 변화가 있었는지 실증적으로 검증하고자 한다. 만약 세월호 사고 이후 소방서비스 환경의 변화가 나타난다면 주민의 안전의식의 변화, 정부의 지원 등을 판단할 수 있는데, 이를 위하여 본 연구는 연구가설 5개를 설정하여 채택여부를 검증하고자 한다. 본 연구에서는 세월호 사고 이전연도는 2013년로, 세월호 사고 이후연도는 2015년도로 하였으며, 주요한 통계기법은 t검정이다. 본 연구의 주요한 결과는 다음과 같다. 첫째, 소방수요는 이전연도와 이후연도 간에 유의미한 차이가 발생하지 않았다. 둘째, 소방예산은 이전연도와 이후연도 간에 유의미한 차이를 보였다. 셋째, 지역자원시설세는 두 연도 간에 유의적인 차이를 보였다. 넷째, 소방수요를 고려한 소방예산은 유의미한 차이를 보이지 않았다. 다섯째, 소방관 1인당 소방수요는 구조, 구급의 경우 모두 이전연도와 이후연도 간에 유의미한 차이를 보였으나, 화재발생의 경우에는 유의미한 차이가 없었다. 여섯째, 소방장비 1개당 소방수요는 모두 두 연도 간에 유의적인 차이를 보이지 못했다. The effects of the Sewol ferry disaster have infiltrated into various fields, such as politics, the economy, and social fields in Korea, and the population"s consciousness of the importance of safety has been strengthened by the disaster. The purpose of, this study is to empirically verify whether there has been any change in the fire service environment following the Sewol ferry disaster. Such a change would be expected to have produced a change in the consciousness of the government about safety and increased the level of support. This study sets out five research hypotheses and verifies their adoption. The years studied are those before and after the accident occurred, viz. 2013 and 2015, respectively, and the main statistical technique is the t-test. The main results of this study are as follows. First, there was no significant difference in the fire-service demand between the two years. Second, the fire-service budget showed a significant difference between the two years. Third, the regional resources facilities tax showed a significant difference between the two years. Fourth, the fire-service budget considering the fire-service demand showed no statistically significant difference. Fifth, the fire service-demand considering (the number of) fire-fighters was significantly different in the rescue and emergency medical services between the two years. Sixth, the fire service-demand considering fire-equipment showed no significant difference between the two years.
국민건강보험 12년 표본코호트자료에 근거한 국내 프로톤펌프저해제 사용 현황
김종주(Jong Joo Kim),장은진(Eun Jin Jang),김대현(Dae Hyun Kim),박한우리(Hanwoori Park),손현순(Hyun Soon Sohn) 대한약학회 2018 약학회지 Vol.62 No.3
This study was conducted to identify the overall PPI usage from 2002 to 2013 (12 years) in real world settings using the sample cohort data from the National Health Insurance Service. The number of PPI users increased by about 10.6 times over 12 years and the average annual growth rate was 26.5%. Annual PPI drug expenditure increased by 16.8 times during the period, with an average annual growth rate of 31.6%. PPI products mainly were prescribed in clinics, as primary medical institutions, accounting for 65% of overall prescriptions. Rabeprazole was the most frequently prescribed ingredient among the seven PPIs available in Korea, accounting for about 51% of all PPI users. Although rabeprazole accounted for more than half of the prescriptions in clinic (rabeprazole 55.5%, esomeprazole 21.0%), it was used at similar levels to esomeprazole in general hospitals (rabeprazole 31.1%, esomeprazole 29.8%). Taking into account rapid increase of PPI usage over 12 years, it is necessary to further discussion to establish strategy for safe use of PPI.
자궁내막종의 감별진단을 위한 난소낭종 환자의 혈청 Macrophage Migration Inhibitory Factor (MIF) 농도의 진단적 유용성에 대한 연구
김만기,김유래,홍승화,박연진,지일운,정은환,김학순,Kim, Man Ki,Kim, Yu Re,Hong, Seong Hwa,Park, Yeon Jin,Ji, IL Woon,Jeong, Eun Hwan,Kim, Hak Soon 대한생식의학회 2005 Clinical and Experimental Reproductive Medicine Vol.32 No.3
Objective: To evaluate the usefulness of serum concentrations of macrophage migration inhibitory factor (MIF) of patients with ovarian cysts for differential diagnosis of endometrioama. Method: From Jan. 2003 to Dec. 2004, preoperative serum MIF levels were assessed in 28 women with endometrioma, 32 with benign epithelial tumor, 23 with functional and simple cysts, 22 with benign mature cystic teratoma, and 25 women without ovarian tumor as control. MIF levels were determined using an ELISA (Quantikine Human MIF immunoassay, R&D Systems, Inc., USA). Results: Mean MIF levels were higher in all groups with benign tumors than control (all p<0.01), but there was no significant difference between benign tumor groups (p=0.95). There was no significant correlation between MIF levels and tumor volume, body mass index (BMI) (p=0.635, 0.674 respectively) Serum MIF level had significant correlation with count of WBC and neutrophils (p=0.008, 0.024 respectively), but had no correlation with count of lymhocytes and monocytes (p=0.688, 0.294 respectively). Conclusions: This study showed a marked increase in MIF concentrations in the peripheral blood of patients with endometrioma, but there was no significant difference with other benign tumors. Serum MIF level had significant correlation with count of WBC and neutrophils. These suggest serum MIF level has no usefulness for differential diagnosis of endometrioma from other benign ovarian cysts.
김진(Kim, Jin),정영진(Jung, Young-Jin),김준호(Kim, Jun-Ho),이현준(Lee, Hyun-Joon),홍성언(Hong, Sung-Eon) 한국산학기술학회 2015 한국산학기술학회논문지 Vol.16 No.1
본 연구에서는 현행 국공유지 필지 관리에 관한 현황 및 문제점을 분석하고, 이를 기초로 국공유지 필지의 효율적 관리를 위한 개선방안을 제시하고자 하였다. 이를 위해 국공유지 관리의 현황과 문제점을 분석하였다. 분석된 문제점으로, 필지 관리 미흡에 따라 필지 수가 지속적으로 증가하고 있는 것으로 나타났다. 증가량은 2008년 기준으로 매년 평균적으로 128,520필이 증가하고 있는 것으로 분석되었다. 그리고 현황과 지적공부의 토지이용상황이 불일치하는 문제가 나타나고 있는것으로 분석되었다. 이와 같은 문제점에 기초해 군소필지가 난립되고, 이는 필지 관련 통계자료 조사 산정시 오류가 포함되어 통계정보의 신뢰성에 문제가 있을 수 있는 것으로 나타났다. 연구에서는 이러한 문제점을 개선하기 위한 방안으로 합병을 통한 필지수 감소, 지적확정측량을 통한 지적정보 관리의 신뢰성 확보, 현황 중심의 국공유지 필지의 등록· 관리를 제시하였다. This study analyzes the status and problems of current parcel management in the public land, and it suggests measures for improvement based on the analysis. For this, it looked into the status and problems of the public land’s parcel management. One of the major problems was that the number of parcels was continuously increasing due to insufficient parcel management. The study found that the number was increasing every year by 128,520 parcels on average as of 2008. It also found that there was also non-coincidence between the status and the land use conditions in the cadastral records. An increasing set of minute parcels (minute polygon) has appeared because of these outstanding issues, and these errors have been included in the statistics survey on parcels, negatively influencing the credibility of the data. This study suggests ways to improve these issues including reduction in the number of parcels through annexation, enhancement of credibility of cadastral information through cadastral confirmation survey, and registration and management of public land parcels in consideration of the current status.
정상체중 중년 남성의 내장지방이 증가할 경우 혈중 염증지표는 어떻게 나타나는가
김기진(Kim, Ki Jin) 계명대학교 생활과학연구소 2014 科學論集 Vol.40 No.-
The aim of the current study was to examine the associations of visceral adiposity with C-reactive protein, IL-6, and TNF-α in 110 middle-aged male subjects selected from the non-obese population. Subjects were divided into 2 groups as non-obese and visceral obese based upon VSR and visceral adiposity for using a cross-sectional approach. I measured anthropometric factors (BMI, percent body fat, WHR, and abdominal fat area by CT scanning), blood levels of fibrinogen, CRP, IL-6, adiponectin, and TNF-α. The measures of adiposity (BMI, percent body fat, WHR) and physical fitness showed no significant difference between two groups. Abdominal fat area and VSR of visceral obese group showed the significant higher values than non-obese group. Blood levels of hsCRP and fibrinogen were significantly (p<0.05) increased concentrations in visceral obese group. Visceral fat area was a significant risk factor for blood level of hsCRP and fibrinogen in spite of middle-aged non-obese male subjects.