돋보기- DB BSI 및 CSI 조사결과

김정미,Kim, Jeong-Mi 한국데이터베이스진흥원 2004 디지털콘텐츠 Vol.5 No.-

2분기 DB산업 기업경기가 완만한 회복세를 보일 것으로 전망됐다. 한국데이터베이스진흥센터(KDPC)가 최근 발표한 2분기 DB산 업 기업경기(BSI) 조사결과에 따르면 DB BSI 실적은 지난해 3분기를 최저점으로 확연히 상승세(2003년 3분기 39 → 2003년 4 분기 46 → 2004년 1분기 80)로 돌아섰으며, 2분기 전망 또한 1분기에 이어 평년수준(100)를 넘어설(119) 것으로 전망했다.

Molecular Diversity of Chrysoviruses in Korean Isolates of A New Fungal Species, Cryphonectria nitschkei

김정미,Jung-Ae Kim,Jin-Ah Park,박승문,차병진,Moon-Sik Yang,김대혁 한국미생물학회 2009 The journal of microbiology Vol.47 No.4

Genetic diversity of the chrysovirus within the four fungal strains was analyzed by comparing the full- length sequences of cloned chrysoviral genes encoding the RNA-dependent RNA polymerase (RdRp) and capsid protein (CP). Because the morphological characteristics of four chrysovirus-infected Cryphonectria spp. strains were different, strain identification was conducted via sequence comparison of the internal transcribed spacers (ITSs) of the fungal rRNA gene. Phylogenic analysis of the ITS regions revealed that the four strains were closely clustered with the reference strain of Cryphonectria nitschkei, while they were more distantly related to other common Cryphonectria species, indicating that they were likely C. nitschkei. Sequence comparison among chrysoviruses from Korean C. nitschkei strains revealed that similarities of the RdRp and CP genes ranged from 98% to 100% and from 95% to 100%, respectively, at the protein level. Their corresponding nucleotide sequences showed 97% to 100% and 84% to 100% identities, respectively. Compared to RdRp, the CP gene had more divergence, suggesting the presence of genes possessing different evolutionary rates within the chrysovirus genome. Sequence comparisons with other known chrysoviruses showed that the four Korean chrysoviruses were clustered together at the next lineage level. Discovering why two strains (bs131 and bs132) containing identical ITS sequences and chrysoviruses display different phenotypes should prove interesting.

The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults

김정미,김보현,이현기,Eun Heui Kim,김미진,Jong-Ho Kim,Yun Kyung Jeon,김상수,김인주,김용기 대한당뇨병학회 2019 Diabetes and Metabolism Journal Vol.43 No.6

Background: Thyroid disease and metabolic syndrome are both associated with cardiovascular disease. The aim of this study was to investigate the correlation between thyroid hormones and obesity sub-phenotypes using nationwide data from Korea, a country known to be iodine replete. Methods: This study was based on data obtained from the sixth Korea National Health and Nutrition Examination Survey, administered from 2013 to 2015. A total of 13,873 participants aged ≥19 years were included, and classified into four groups: metabolically healthy non-obesity (MHNO), metabolically healthy obesity (MHO), metabolically unhealthy non-obesity (MUNO), and metabolically unhealthy obesity (MUO) by body fat on the basis of body mass index and metabolic health. Results: At baseline, serum free thyroxine (fT4) values were significantly higher in the MHNO phenotype (MHNO, 1.27±0.01 ng/dL; MHO, 1.25±0.01 ng/dL; MUNO, 1.24±0.01 ng/dL; MUO, 1.24±0.01 ng/dL, P<0.001) in total study population. However, this significant association no longer remained after adjustment for age, urine iodine concentration, and smoking (P=0.085). After adjustment for confounders, statistically significant association was observed between lower thyroid stimulating hormone (TSH) and MHNO phenotype (P=0.044). In men participants (not women), higher fT4 values were significantly associated with MHNO phenotype (P<0.001). However, no significant association was observed between thyroid function (TSH or fT4) and obesity phenotypes in groups classified by age (cutoff age of 55 years). Conclusion: Although there was a difference by age and sex, we found that the decrease of TSH and the increase of fT4 values were associated with MHNO.

AMC G-Box를 이용한 영상유도장치의 효율적인 정도관리

김정미,Kim, Chong Mi 대한방사선치료학회 2014 대한방사선치료학회지 Vol.26 No.2

목 적 : 최근 영상유도 방사선치료의 급증에 따라 영상유도장치의 정도관리를 철저히 시행할 필요가 있다. 특히 영상유도 방사선치료는 장치의 정확성을 기본 전제로 하기 때문에 이에 대한 정도관리가 필수적으로 행해져야 한다. 본원에서는 영상유도장치의 정도관리를 기존의 팬텀(Phantom)보다 효율적인 팬텀을 자체 제작하여 정확하고 효율적인 정도관리를 이행하고자 한다. 대상 및 방법 : 영상유도장치의 정도관리 항목으로 매우 중요한 5가지를 설정하고, 그 항목에 대하여 효율적이고 정확한 정도관리가 이루어 질 수 있는 팬텀(AMC G-Box)을 자체 제작하였다. 정도관리 항목은 Iso-center와 영상유도장치의 중심 일치성, 구현된 영상의 실측 정확성, 4 방향의 중심일치성, 영상유도 이동의 정확성 및 CBCT(Cone Beam CT)에서 구현된 HU(Hounsfield Unit)의 재현성으로 설정하였다. 이 항목에 대하여 $10cm{\time}10cm{\time}10cm$의 정사각형 팬텀을 1 cm두께의 아크릴로 제작하였으며 CBCT HU을 측정하기 위해 팬텀안에 각각 밀도가 다른 3개의 물질을 삽입하였다. 팬텀에는 중심과 일정한 위치를 가리키는 표식을 만들어서 중심과 일치성 검사를 할 수 있도록 하였다. 실험은 기존 각각의 팬텀을 이용한 정도관리를 실시하고, 새로 제작된 AMC G-Box로 실시한 후 그 결과 값을 비교하고 소요되는 시간과 문제점을 분석하였다. 사용된 치료기는 Varian사의 4개의 모델이고, 1주 간격으로 2회 측정하였다. 결 과 : 완성된 AMC G-Box를 이용한 영상유도장치의 정도관리를 시행하였을 때, 기존 개별로 구성된 팬텀을 이용한 정도관리 결과를 보았을 때, $0.2mm{\pm}0.1$이내에서 결과 값이 같았다. 또한 기존의 방법일 경우 최소 30분에서 45분이 소요되었으나, AMC G-Box를 이용하였을 때는 15분~20분이 소요되어 50%이상 시간을 감소하였다. 결 론 : 영상유도장치는 사용기간이 지남에 따라 일치성과 정확성이 떨어지는 경향이 있다. 따라서 관련된 정도관리를 주기적으로 철저하게 할 필요성이 있다. 특히 일치성 검사는 매일 점검해야하는 항목이다. 이러한 정도관리를 AMC G-Box를 이용할 경우 정확한 정도관리를 효율적으로 실시함으로써, 장치와 환자 치료의 안정성과 정확성을 높일 수 있었다. Purpose : According to the rapid increase recently in image-guided radiation therapy, It is necessary to control of the image guidance system completely. In particular for the main subject to the accuracy of image guided radiation therapy device to be done essentially the quality assurance. We made efficient phantom in AMC for the management of the accurate and efficient. Materials and Methods : By setting up of five very important as a quality assurance inventory of the Image guidance system, we made (AMC G-Box) phantom for quality assurance efficient and accurate. Quality assurance list were the Iso-center align, the real measurement, the center align of four direction, the accuracy of table movement and the reproducibility of Hounsfield Unit. The rectangular phantom; acrylic with a thickness of 1 cm to $10cm{\time}10cm{\time}10cm$ was inserted the three materials with different densities respectively for measure the CBCT HU. The phantom was to perform a check of consistency centered by creating a marker that indicates the position of the center fixed. By performing the quality assurance using the phantom of existing, comparing the resulting value to the different resulting value using the AMC G-Box, experiment was analyzed time and problems. Therapy equipment was used Varian device. It was measured twice at 1-week intervals. Results : When implemented quality assurance of an image guidance system using AMC G-Box and a phantom existing has been completed, the quality assurance result is similar in $0.2mm{\pm}0.1$. In the case of the conventional method, it was 45 minutes at 30 minutes. When using AMC G-Box, it takes 20 minutes 15 minutes, and declined to 50% of the time. Conclusion : The consistency and accurate of image guidance system tend to decline using device. Therefore, We need to perform thoroughly on the quality assurance related. It needs to be checked daily to consistency check especially. When using the AMC G-Box, It is possible to enhance the accuracy of the patient care and equipment efficiently performing accurate quality assurance.

학령기 단순언어장애아동의 이해모니터링 능력

김정미,Kim Jung-Mee 대한음성학회 2004 말소리 Vol.51 No.-

Comprehension monitoring is a process of message evaluation and a very important skill of communication. Comprehension monitoring is a necessary language skill in classroom, as it is important for children to assess their own understanding of task instructions and teaching content. The present study investigated comprehension monitoring skill of children with Specific Language Impairment(SLI) compared to age-matched children and language-matched children. 18 vignettes and 6 displays were constructed. Children were asked to choose one object or 'DK' card from a display after the children listened to the vignettes. The results showed that children with SLI didn't have problem in comprehending unambiguous utterance and using prior statement. However, they had problem in monitoring comprehending ambiguous utterance compared age-matched children. Their performance were similar to language matched younger children. With respect to their performance, several possible explanations were discussed.

아로마테라피용 배초향(Agastache rugosa) 줄기의 방향성 정유 성분

김정미,Kim, Jeong-Mee 한국식생활문화학회 2021 韓國食生活文化學會誌 Vol.36 No.3

This study was carried out to investigate the flavoral essential oil components in the stems of Agastache rugosa. These components were analyzed using gas chromatography-mass selective detector (GC-MSD). The stems of Agastache rugosa were contained alcohols, aldehydes, ketones, fatty acid esters, and terpenoids. The peak area (%) of estragole was highest among its oil components and the next were pulegone and menthone. The terpenoid alcohols found were 1-octen-3-ol, chavicol, spatulenol, 3-hexen-1-ol, 2-cyclohexen-1-ol, methyl eugenol, and octaethyllene glycol. The stems also contained ketones such as pulegone, menthone, cis-isopulegone, 2-cyclohexene-1-one, 3-octanone, 1-cyclohexanone, isoindole-1-one, t-ionone, inden-2-one, as well as the aldehydes of 4-methoxycinnam and benzaldehyde. The following esters were also detected 1-isopulegone-3-yl acetate, caryophyllene oxide, acetate and benzendicarboxylic acid ester. The terpenoids in the stems were identified as caryophyllene, limonene, cyclohexasiloxane-D, germacrene-D, anethole, cadinene, muurolene, and bourbonene. Overall Agastache rugosa contained several functional oil components including phenylpropanoids and terpenoids as flavoral essential oil components for natural aromatherapy.

청둥오리의 가슴샘 내분비세포에 대한 면역조직화학적 연구

김정미,이재현,구세광,이형식,Kim, Jeong-mi,Lee, Jae-hyun,Ku, Sae-kwang,Lee, Hyeung-sik 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.2

Endocrine cells in the thymus of duck(Anas platyrhynchos platyrhyncos, Linne) were studied immunohistochemically from 23 days of incubation to 32 weeks of age. Somatostatin-, growth hormone(GH)-, gastrin/cholecystokinin(Gas/CCK)-, polypeptide YY(PYY)-, S-100 protein(S-100 P)-, dopamine-, serotonin(5-HT)-, and bovine chromogranin (BCG)-immunoreactive cells were detected in the duck thymus by the PAP techniques. These immunoreactive cells were observed in the medulla and in the juxtacortical medulla. No immunoreactivity of calcitonin and bovine pancreatic polypeptide(BPP) antiserum were observed. The argyrophil cells by Grimelius techniques were observed from 23 days of incubation to 32 weeks of age and peaked in 5 weeks of age. In the early develpmental stage, the argyrophil cells were distributed only in the medulla, while these cells were distributed mainly in the medulla and a few cells were distributed in the corticomedullary junction from 3 weeks of age. These immunoreactive cells were generally round, oval and elliptical and occasionally spindle, polygonal and polymorphous with the long cytopslasmic processes in shape. The present study suggests that the intrathymic endocrine cells may associate with the functional maturation of T-lymphocytes on the establishment of immunity. The further study will be needed to elucidate the function of these thymic endocrine cells.

CONTENT PRISM / 3/4분기 DB산업 전망 '맑음'

김정미,Kim, Jeong-Mi 한국데이터베이스진흥원 2003 디지털콘텐츠 Vol.8 No.-

2003년도 국내 DB관련 업체를 대상으로 종합경기, 내수판매, 수출, 투자, 자금사정, 채산성, 고용 등 7영역에 대해 DB산업 경기실사지수(DB_BSI)를 조사한 결과, 1/4분기에 비해 2/4분기 경기실적은 다소 회복된 것으로 조사됐다. 이와 같은 호전세는 3분기에도 지속될 전망이나 세계경제의 부진, 중증급성호흡기증후군(SARS)으로 인한 중국시장 부진, 북핵문제를 둘러싼 지정학적 위협, 가계 부채 증가 등에 따른 시장부진 등의 악재로 인해 보합세(100)에는 미치지 못할 것으로 전망된다.

가물치 위장관 내분비세포에 관한 면역조직학적 관찰

김정미,이재현,Kim, Jeong-mi,Lee, Jae-hyun 대한수의학회 1992 大韓獸醫學會誌 Vol.32 No.3

The regional distribution and relative frequency of occurrence of endocrine cells in nine segments of the gastrointestinal(GI) tract of snakehead(Ophicephalus argus) were investigated by immunohistochemical methods using specific antisera against 5- hydroxyptrytamine(5-HT), somatostatin, gastrin/cholecystokinin(GAS/CCK), glucagon, bovine chromogranin, porcine chromogranin and insulin. Four types of immunoreactive cells for 5-HT, somatostatin, GAS/CCK and glucagon were observed in the GI tract. These cells were generally appeared in the mucosal epithelia or located at the interface of the mucosal epithelial layer and intestinal glandular region. 5-HT-immunoreactive(IR) cells were found in segment II, III, IV, V and VI, and the most numerous in segment IV. Somatostatin-IR cells were found in segment II, III, IV and V, and the most numerous in segment III. GAS/CCK-IR cells in segment VI, VII and glucagon-IR cells in segment III, IV, V were detected but a few in these segments. No bovine chromogranin-, porcine chromogranin- and insulin-IR cells were detected throughout the GI tract of the snakehead.

보리순 분말을 첨가한 쿠키의 품질특성

김정미,Kim, Jung-Mi 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.5

This study examined the quality characteristics of cookies comprised of various amounts of barley-sprout powder by analyzing the physico-chemical characteristics of the cookies and investigating a sensory evaluation. For the study, the cookies were cooked with the following levels of barley-sprout powder: 0%, 3%, 6%, 9%, and 12%. The results show that the moisture content of the cookies was increased in accordance with the level of barley-sprout powder and this result is the same as the spreadability factor of the cookies (p<0.001). Also, the pH and brix values of the samples decreased in accordance with the level of barley-sprout powder (p<0.001). Regarding hunter's colors, the values of L (lightness), a (redness), and b (yellowness) are significantly decreased, increasing the quantity of barley-sprout powder (p<0.001). For the textural characteristics, the results show that the hardness of the cookies decreased in accordance with the addition of the barley-sprout powder; furthermore, the results indicate a tendency whereby the DPPH-radical-scavenging activity and the total polyphenol content of the cookies were increased, thereby increasing the quantity of the barley-sprout powder (p<0.001). For the sensory evaluation, the cookies that were made with 6 % barley-sprout powder received the highest scores in terms of appearance, taste, and overall preference (p<0.05, p<0.001). This study suggests that barley-sprout powder is an excellent ingredient for improving the acceptability and functionality of cookies, and that, in relation to the flour quantity the ideal proportion of barley-sprout powder is 6%.