미세각막절개 백내장 수술 후 낭내 삽입한 일체형 비구면 인공수정체의 임상 결과

김윤전,전미현,고동아,김재용,김명준,차흥원,Yoon Jeon Kim,Mi Hyun Cheon,Dong Ah Ko,Jae Yong Kim,Myoung Joon Kim,Hung Won Tchah 대한안과학회 2013 대한안과학회지 Vol.54 No.4

Purpose: To evaluate the stability and optical performance of the newly developed single-piece aspheric intraocular lens (IOL) by comparing the clinical outcome of the aspheric IOL with the new optic profile design (HOYA iSert, HOYA iMics) and the aspheric IOL (Akreos MI60), which has been proven effective and safe. Methods: iSert, iMics, and MI60 were inserted into 55 eyes, 60 eyes, and 50 eyes, respectively, after microincision phacoemulsification cataract surgery. Best corrected visual acuity (BCVA), refraction in spherical equivalent, anterior chamber depth (ACD), total higher order aberration (HOA), contrast sensitivity, and surgically induced astigmatism (SIA) were measured and each IOL was evaluated on the functional stability, anterior-posterior stability, centration in the capsular bag, and quality of vision. Results: No statistical differences in preoperative and postoperative BCVA among the 3 IOL groups were observed, however, MI60 showed significant myopic shift postoperatively. Anterior-posterior stability assessed with postoperative change in refractive error and ACD was slightly lower in the MI60 group. In terms of vision quality, while total aberration, total HOA, coma aberration, and contrast sensitivity for the 3 IOLs were not different significantly, spherical aberration of the MI60 group was higher than the other groups at 6 months postoperative. SIA was significantly increased in eyes implanted with iSert than in eyes with iMics or MI60 at 1 month postoperatively, however, the differences were no longer evident after 3 months postoperatively. Conclusions: The new aspheric IOLs, iSert and iMics, showed good stability and visual outcome equal to MI60 at the 6-month postoperative follow-up.

중심각막두께와 녹내장성 손상의 상관관계에 대한 연구

김윤전,나정화,이영록,성경림,Yoon Jeon Kim,Jung Hwa Na,Youngrok Lee,Kyung Rim Sung 대한안과학회 2012 대한안과학회지 Vol.53 No.7

Purpose: To evaluate the correlations between central corneal thickness (CCT) and optic disc and retinal nerve fiber layer (RNFL) parameters determined by spectral domain optical coherence tomography (SD OCT) and visual field (VF) global indices. Methods: The present study included 151 eyes diagnosed with open-angle glaucoma (OAG) and 135 glaucoma suspect (GS) eyes. The CCT, RNFL thickness, optic disc parameters, and VF global indices were measured. The relationships between CCT and RNFL thickness, optic disc parameters, and VF global indices were assessed by linear regression analysis. Results: Intraocular pressure (IOP, p < 0.001) and VF mean deviation (p = 0.005) in all participants, age (p = 0.017) and IOP (p = 0.003) in the GS group, and IOP (p = 0.002) and inferior RNFL thickness (p = 0.017) in the OAG group were significantly associated with CCT. Among the optic disc parameters, rim area, average cup/disc ratio, and vertical cup/disc ratio were significantly associated with CCT in all participants in the univariate but not multivariate analysis. Conclusions: Optic disc parameters obtained by SD OCT were not correlated with CCT in the OAG or GS group, while RNFL thickness and VF mean deviation showed associations. J Korean Ophthalmol Soc 2012;53(7):1002-1010

눈과 류마티스질환

김윤전 ( Yoon Jeon Kim ),이주용 ( Joo Yong Lee ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.3

Rheumatic disorders commonly affect the sclera, cornea, retina, and orbit. These disorders range from relatively mild ocular surface problems to a serious threat for the visual sight. The most common ocular manifestations of rheumatic diseases include keratoconjunctivitis sicca, anterior uveitis, and scleritis. The most common entities to causing anterior uveitis and scleritis are seronegative spondyloarthropathies associated with human leukocyte antigen (HLA)-B27 and rheumatoid arthritis, respectively. Patients who developed bilateral or recurrent uveitis, or who have involvement of posterior ocular structures are more likely to have underlying systemic inflammatory diseases. The most significant side effects of the drugs used to treat rheumatic diseases are the maculopathy-associated with anti-malarial agents and cataracts and glaucoma associated with corticosteroid use. Close collaborations between ophthalmologists and rheumatologists are necessary for optimal treatments and the prevention of complications. Understanding the range and patterns of ocular manifestations of rheumatic diseases can provide valuable suggestions for the most suitable diagnosis and optimal management for these patients.

중심와를 침범한 감염성 포도막염에서 발생한 황반원공의 자연폐쇄 1예

김민우(Min Woo Kim),김동윤(Dong Yoon Kim),김윤전(Yoon Jeon Kim),조수근(Soo Geun Joe),이주용(Joo Yong Lee),김중곤(June Gone Kim) 대한안과학회 2016 대한안과학회지 Vol.57 No.1

Purpose: To report a case of macular hole secondary to presumptive infectious posterior uveitis involving the fovea that spontaneously resolved after medical treatment. Case summary: A 33-year-old male visited our clinic for decreased visual acuity in his left eye. He was treated with immunosuppressive therapy including steroid after bone marrow transplantation. Best corrected visual acuity (BCVA) was 0.05 in the left eye. Slit lamp examination showed mild anterior vitritis, and fundus examination showed a macular hole with surrounding whitish infiltration at the fovea. Spectral domain optical coherence tomography (SD-OCT) revealed a full thickness macular hole with surrounding hyper-reflective masses with an infiltration-like appearance involving all retinal layers. Serum anti-toxocara IgG was positive (ELISA), and eosinophil count and immunoglobulin E was elevated. Under diagnosis of presumptive ocular toxocariasis, the patient was treated with albendazole. After medical treatment for toxocariasis, the whitish foveal infiltration became smaller and more discrete. SD-OCT revealed spontaneous closure of the macular hole, and BCVA was improved to 0.4 after a 4-month follow-up. Conclusions: We report a macular hole complicated by presumptive infectious posterior uveitis that experienced spontaneous closure after medical treatment for underlying infection.

안내이물의 임상양상 및 예후인자

심규영,김윤전,김중곤,윤영희,이주용,Kyu Young Shim,Yoon Jeon Kim,MD,June Gone Kim,MD,Young Hee Yoon,MD,Joo Yong Lee,MD 대한안과학회 2013 대한안과학회지 Vol.54 No.3

Purpose: To investigate clinical characteristics of post-traumatic intraocular foreign body (IOFB), which occurred between 2006 and 2010, and prognostic factors associated with final visual outcome. Methods: A retrospective chart review was performed of patients with IOFB who visited our clinic from January 1, 2006 to December 31, 2010, and who were followed up for more than 6 months. Cross tabulation and correlation analyses were conducted to evaluate the predictive factors related to final visual acuity. Results: A total of 36 eyes (35 patients) were included in this study. The mean age was 44.2 years, and 33 patients (94.3%) were male. The most common cause of IOFB was lawnmower-related activity (12 patients; 33.3%) and hammering-related activity (11 patients; 30.1%). Among analyzed prognostic factors, only initial visual acuity was significantly correlated with visual outcomes (p < 0.001). Conclusions: Compared with previous studies, lawnmower and hammering-related activities were still the most common causes of IOFB, however, the incidence of occurrence in the 40’s and 50’s was relatively higher than in previous studies. Considering the poor visual outcome of IOFB even after proper surgical treatment, using proper eye protection should be emphasized in a dangerous work environment to prevent ocular trauma.

한국인에서 개정된 눈 사르코이도시스 진단 기준의 임상적 효용성에 대한 분석

박지민(Jimin Park),김유나(You Na Kim),김윤전(Yoon Jeon Kim),김중곤(June Gone Kim),윤영희(Young Hee Yoon),이주용(Joo Yong Lee) 대한안과학회 2021 대한안과학회지 Vol.62 No.9

목적: 2017년 6차 International Workshop for Ocular Sarcoidosis (IWOS)에서 개정 발표된 눈 사르코이도시스 진단 기준을 2009년 발표된 1차 IWOS 진단 기준과 비교 분석하고, 이를 한국인 눈 사르코이도시스 진단에 활용했을 때의 임상적 효용성을 알아보고자 한다. 대상과 방법: 2007년부터 2018년까지 서울아산병원 안과에서 포도막염으로 진단받은 환자들 중 호흡기내과 및 안과 정밀검진을 시행 후 눈 사르코이도시스로 진단된 환자들의 의무기록을 후향적으로 분석하였다. 내과에서 시행한 혈액검사, 영상학적 검사 및 조직검사 결과와 안과 검진 시 시행한 세극등현미경검사, 안저검사, 형광안저 혈관조영술 결과를 종합하여 2009년 및 2017년 IWOS 진단 기준에 따라 눈 사르코이도시스를 진단하였다. 결과: 눈 사르코이도시스로 진단된 총 34명의 의무기록을 분석하고 두 진단 기준을 활용하여 분류하였다. 조직검사를 시행한 32명의 환자 중 31명이 조직검사상 사르코이도시스로 진단되었다(양성률 96.87%). 31명이 definite ocular sarcoidosis (OS), 2명이 presumed OS로 이전 진단 기준과 개정된 진단 기준에서 동일하게 분류되었고, 1명의 환자만 기존 진단 기준에서는 possible OS, 개정된 진단 기준에서는 presumed OS로 분류되었다. 결론: 조직검사 양성률이 높고, 영상학적 검사의 질이 높은 우리나라의 임상상황에서는 이전 진단 기준과 비교하여 개정된 진단 기준을 활용하였을 때 진단 결과에 큰 차이는 없을 것으로 사료된다. Purpose: To compare differences between the original criteria for diagnosis of ocular sarcoidosis (OS) (first International Workshop for OS [IWOS] 2009) and the revised criteria (sixth IWOS 2017), and their clinical usefulness when assessing OS in Korean patients. Methods: We analyzed patients with suspected OS who visited our tertiary referral ophthalmological and pulmonary clinic from 2007 to 2018. We diagnosed patients using both sets of criteria. Blood test and biopsy data (collected by physicians) and slit-lamp, fundus, and fluorescein angiography data (collected by ophthalmologists) were reviewed. Results: Thirty-four patients were diagnosed using both criteria. Of 32 patients who underwent biopsies, 31 had OS (96.87%). Using either set of criteria, 31 patients were diagnosed with definite OS and two with presumed OS. One patient diagnosed with possible OS using the previous criteria was diagnosed with presumed OS using the revised criteria. The new criteria add the lysozyme level, the CD4/CD8 ratio, and positron emission tomography imaging data to the old criteria and add the descriptors “presumed OS” and “probable OS”. There is no need to use the revised criteria in Korea; the biopsy and imaging data are adequately diagnostic. Conclusions: IWOS revised the OS diagnostic criteria by adding new parameters. However, this was unnecessary for Korea, where the biopsy and imaging data are adequately diagnostic.

고등교육 경쟁력 지표 개발 연구 (1) : 세계대학 경쟁력 지표의 비교 및 시사점

신현석 ( Hyun Seok Shin ),엄준용 ( Joon Yong Uhm ),노명순 ( Myeong Soon Noh ),최보윤 ( Bo Yoon Choi ),김윤전 ( Yoon Jeon Kim ) 한국인력개발학회 2008 HRD연구 Vol.10 No.1