파노라마방사선사진을 이용한 연령별 하악 피질골 두께에 관한 연구

김윤숙,김경아,고광준,Kim, Yun-Suk,Kim, Kyoung-A,Koh, Kwang-Joon 대한영상치의학회 2010 Imaging Science in Dentistry Vol.40 No.2

Purpose : This study was to determine the relationship between age and the mandibular cortical bone thickness on panoramic radiograph. Materials and Methods : Panoramic radiographs of 360 patients (180 men and 180 women) over 20 years old, who visited the Chonbuk National University Hospital from January to December in 2007, were assessed. The subjects were divided into 5 age groups. Five indices such as cortical bone thickness at the gonion (GI), antegonion (AI), and below the mental foramen (MI), the panoramic mandibular index (PMI), the mandibular cortical index (MCI) were measured on panoramic radiographs. Results : All five indices including GI, AI, MI, PMI, and MCI showed significant differences between third decade and over 8 decade groups (p<0.05). PMI, MI and GI showed significant differences with gender statistically (p<0.05). Conclusion : The mandibular cortical bone thickness showed negative correlation with age, and the value of the thickness (PMI, MI, and GI) was greater in men than in women.

저지방 육제품개발에 대한 연구동향

김윤숙,유익종,Kim, Yun-Suk,Yu, Ik-Jong 한국식품연구원 1994 食品技術 Vol.7 No.3

저지방 육제품 개발에 대한 연구동향

김윤숙,유익종,Kim, Yun-Suk,Yu, Ik-Jong 한국육가공협회 1994 肉加工 Vol.10 No.-

일부 야생 및 배양 버섯 중의 sterol 및 vitamin $D_2 함량

김윤숙,Kim, Yun-Suk 한국식품연구원 2002 食品技術 Vol.15 No.2

일부 야생 및 배양 버섯중의 sterol 및 vitamin $D_2함량을 측정하였다. 야생버섯의 부위별 이들 성분의 분포 또한 평가되었다. 또 야생버섯의 자실체의 vitamin $D_2함량의 변화도 연구되었다. vitamin $D_2는 비누화 및 반예비 순상 HPLC 정제를 포함하는 방법을 사용한 후 HPLC법을 사용하여 측정하였는데, 내부 표준품을 이용한 분석용 역상컬럼을 이용한 정량을 하였다. Sterol 함량은 GC로 분석되었으며, 내부표준품을 사용하였다. 비누화 후에 sterol을 trimethylsily1 ester로 유도체화하여 분석의 시료로 하였다. 질량분석이 sterol류의 동정을 확인하기 위하여 사용되었다. 배양 버섯에서는 vitamin $D_2는 거의 존재하지 않았으나, 일부 야생 버섯은 이들 vitamin을 다량(4.7- 194$\mug$/ 100g 건물중) 함유하고 있었다. Ergosterol은 버섯류 중에 가장 많이 존재하는 sterol이었으며, 야생버섯류(296-489 mg/ 100g 건물중)보다 배양버섯류(602.1-678.6 mg/ 100g 건물중)에서 높은 함량을 보였다. Vitamin D2와 ergosterol의 함량은 버섯류의 부위에 따라 아주 다양하거나 적당한 변화를 보였으며, 자루부위에서 가장 낮은 함량을 보였다. 더욱이 개체별 자실체간의 vitamin $D_2함량간에도 많은 차이를 보였다.

국내 산과 전문의의 임신 중 고혈압성 질환 임상진료패턴 분석

안태규 ( Tae Gyu Ahn ),김연희 ( Yeon Hee Kim ),김윤숙 ( Yun Sook Kim ),신재은 ( Jae Eun Shin ),오영림 ( Young-Lim Oh ),이순애 ( Soon Ae Lee ),이민아 ( Mina Lee ),이귀세라 ( Gui Se Ra Lee ),김석영 ( Suk Young Kim ),김수미 ( Su-Mi Ki 한국모자보건학회 2021 한국모자보건학회지 Vol.25 No.3

Purpose: The purpose of this study was to investigate the clinical practice patterns of Korean obstetricians and gynecologists the diagnosis and management of hypertensive disease in pregnant women. Methods: From April 2015 to October 2015, questionnaire was distributed via email to obstetricians who were members of the Society for Maternal and Fetal Medicine. The survey consisted of 37 questions in 6 categories. Responses to the questions on the management of hypertensive disorders of pregnancy, from diagnosis to treatment, were evaluated. Results: A total of 93 obstetricians and gynecologists responded to the survey. High blood pressure was allocated the highest priority as an index mainly used when deciding to hospitalize patients with hypertensive disease during pregnancy, followed by pregnancy symptoms, proteinuria, and blood test results. Calcium channel blocker (CCB) for oral administration and hydralazine for injection were preferred as antihypertensive drugs mainly used to control severe hypertension. Regarding the delivery method for hypertensive disease during pregnancy, in cases of preeclampsia, 63% of the respondents chose the delivery method according to the cervical status, and in cases of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome and eclampsia, which increased in severity, 52% and 31% responded that the delivery method was determined according to the cervical status, respectively. In cases of mild preeclampsia, the 70% of respondents preferred 37-38 weeks of gestation for the delivery time. Regarding the use of aspirin in patient with hypertension during pregnancy, 52% of the respondents occasionally administered aspirin, and in patients with a history of hypertensive disease during pregnancy, only 43% were administered prophylactic aspirin. Conclusion: Domestic obstetricians regarded blood pressure as the most meaningful factor when treating women with hypertension during pregnancy and considered blood pressure control as important. The preferred antihypertensive agents were oral CCB and hydralazine injections, and the choice of delivery method was determined according to the condition of the cervix and severity of the disease. Even in women with high risk factors for preeclampsia, prophylactic aspirin was administered in as low as 50%, of patients, possibly may due to the absence of domestic guidelines for aspirin use during pregnancy. Korean guidelines for prophylactic aspirin administration during pregnancy is needed based on additional research on the efficacy of aspirin for domestic women in the future.

흰쥐 삼차신경감각핵에서 $P2X_3$와 TRPV1의 공존에 관한 연구

문용석,류창현,조이슬,김홍태,박매자,백상규,문제일,김윤숙,배용철,Moon, Yong-Suk,Ryoo, Chang-Hyun,Cho, Yi-Sul,Kim, Hong-Tae,Park, Mae-Ja,Paik, Sang-Kyoo,Moon, Che-Il,Kim, Yun-Sook,Bae, Yong-Chul 한국현미경학회 2008 Applied microscopy Vol.38 No.3

삼차신경계에서 $P2X_3$와 TRPV1 면역양성 일차들신경섬유는 통각정보의 전달에 중요한 역할을 한다. 본 연구에서는 삼차신경절 및 삼차신경꼬리핵에서 $P2X_3$와 TRPV1 면역양성 신경세포의 형태학적 특성 및 투사양식을 이해하기 위하여, 흰쥐 삼차신경절 및 삼차신경꼬리핵에서 $P2X_3$와 TRPV1에 대한 항체를 사용하여 형광면역염색법 및 형태계측학적인 기법을 시행하여 다음과 같은 결과를 얻었다. $P2X_3$ 면역양성 신경세포중 77.4%의 신경세포에서 (1,401/1,810) TRPV1이 동시에 발현되었으며, TRPV1 면역양성 신경세포중 51.9% (1,401/2,698)의 신경세포에서 $P2X_3$와 공존을 보였다. $P2X_3$와 TRPV1에 동시에 면역양성반응을 보이는 신경세포는 중간크기의 신경세포에서 주로 관찰되었으며, $P2X_3$ 혹은 TRPV1 면역양성 신경세포중 아주 작거나 큰 신경세포에서는 공존하지 않았다. 삼차신경꼬리핵에서 $P2X_3$ 면역양성 신경섬유 및 신경종말들은 제1층과 제2층에 분포하는데 주로 제2층의 안쪽부위에서 밀도가 높게 관찰되었으며, TRPV1 면역양성 신경섬유 및 신경종말들은 제1층과 제2층의 바깥쪽에서 밀도가 높게 관찰되었다. $P2X_3$와 TRPV1이 공존하는 신경섬유 및 신경종말들은 제2층의 안쪽과 바깥쪽의 경계부위에서 관찰되었다. 이러한 연구결과는 $P2X_3$와 TRPV1을 동시에 발현하는 신경세포는 구강안면영역에서 통각정보의 처리에 독특한 역할을 수행할 것이라는 것을 시사한다. Trigeminal primary afferents expressing $P2X_3$ or transient receptor potential vanilloid 1 (TRPV1) are involved in the transmission of nociceptive information. In order to characterize $P2X_3$- and TRPV1-immunopositive neurons in the trigeminal ganglion (TG) and trigeminal caudal nucleus (Vc), we performed immunofluorescence experiments using anti-$P2X_3$ and anti-TRPV1 antisera and a morphometric analysis. 77.4% (1,401/1.801) of all the $P2X_3$-postive neurons coexpressed TRPV1 and 51.9% (1,401/2,698) of all the THFV1-immunopositive neurons also costained for $P2X_3$ in the TG. Immunoreactivity for both $P2X_3$ and TRPV1 were present in medium-sized neurons but not in small- and large-sized neurons. $P2X_3$ and/or TRPV1-immunopositive fibers were observed in the primary afferents and their associated axons in the Vc. These fibers and terminals were distributed in the superficial lamina of Vc: $P2X_3$-immunopositive fibers and terminals were distributed in the lamina I and II, expecially in the inner part of lamina II (lamina IIi), whereas TRPV1-immunopositive ones were densely detected in the lamina I and outer part of lamina II (lamina IIo). Immunopositive fibers and terminals for both $P2X_3$ and TRPV1 were observed on the border between lamina IIi and IIo. These results suggest that terminals coexpressing $P2X_3$ and TRPV1 are involved in specific roles in the transmission and processing of orofacial nociceptive information.

사과 신품종 ‘썸머킹’, ‘아리수’, ‘그린볼’의 저장방법 및 기간에 따른 품질변화

정은호(Eun Ho Jeong),강남대(Nam Dae Kang),김우일(Woo Il Kim),김종원(Jung Won Kim),심순애(Soon Ae Sim),김윤숙(Yun Sook Kim),박은지(Eun Jee Park),심재석(Jae Suk Shim),이상대(Sang Dae Lee),권순일(Soon Il Kwen),신용억(Yong Uk Shin) 한국원예학회 2016 한국원예학회 학술발표요지 Vol.2016 No.10

2010 년 수입식품 현황

오금순(Keum Soon Oh),최은주(Eun Ju Choi),유선영(Sun-Young Yoo),김윤숙(Yun-Suk Kim),홍헌우(Heon-Woo Hong) 한국식품과학회 2011 식품과학과 산업 Vol.44 No.4

Complete Freund Adjuvant에 의한 피부염증에서 통각과민현상의 기전

남택상(Taick Sang Nam),백광세(Kwang Se Paik),정용(Yong Jeong),임중우(Joong Woo Leem),정승수(Seung Soo Chung),김윤숙(Yun Suk Kim),윤덕미(Duck Mi Yoon) 대한통증학회 2000 The Korean Journal of Pain Vol.13 No.2

N/A Background: After an injury to tissue such as the skin, hyperalgesia develops. Hyperalgesia is characterized by an increase in the magnitude of pain evoked by noxious stimuli. It has been postulated that in the mechanism of hyperalgesia (especially secondary hyperalgesia) and allodynia, a sensitization of central nervous system such as spinal dorsal horn may contribute to development of hyperalgesia. However, the precise mechanism is still unclear. In the present study, we investigated the roles of N-methyl-D-aspartate (NMDA) receptor and nitric oxide (NO) system in the mechanism of hyperalgesia, and their relations with c-fos expression. Methods: Inflammation was induced by injection of complete Freund adjuvant (CFA) into unilateral hindpaw of Sprague-Dawley rat. Behavioral studies measuring paw withdrawal responses by von Frey filaments and paw withdrawal latencies by radiant heat stimuli and stainings of nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase and c-fos immunoreactivity were performed. The effects of MK-801, an NMDA receptor blocker and Nw-nitro-L-arginine (L-NNA), a nitric oxide synthase (NOS) inhibitor were evaluated. Results: 1) Injection of CFA induced mechanical allodynia, mechanical hyperalgesia and thermal hyperalgesia. And it increased the number of NADPH-diaphorase positive neurons and c-fos expression neurons. 2) MK-801 inhibited mechanical hyperalgesia and thermal hyperalgesia induced by CFA and reduced the number of NADPH-diaphorase positive neurons and c-fos expression neurons. 3) L-NNA inhibited the thermal hyperalgesia and reduced the number of NADPH-diaphorase positive neurons, but did not affect the number of c-fos expression neurons. Conclusions: These results suggest that in the mechanism of mechanical hyperalgesia, NMDA receptor but not NO-system is involved and in the case of thermal hyperalgesia both NMDA receptor and NO system are involved. NO system did not affect the expression of c-fos, but c-fos expression and NOS activity were dependent on the activity of NMDA receptor.