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김완태(Kim, Wan-Tai),정관옥(Chung, Kwan-Ogg),김윤선(Kim, Yoon-Sun),조용문(Cho, Yong-Moon),정원근(Chung, Won-Keun),남기용(Nam, Kee-Yong) 대한생리학회 1970 대한생리학회지 Vol.4 No.1
Erythropoietic activity in anemic Plasma of chronic posthemorrhagic anemic men was studied in rats after subcutaneous injection of anemic plasma. Anemic plasma was obtained from blood donors who sold their blood once or twice a week for one or two years to blood bank. Hemoglobin concentrations of 8 blood donors ranged between 4.6 and 8.4 gm/100 ml. Pooled plasma was treated by acidification-boiling method and adjusted to pH 7.5 by adding 0.1 N NaOH. 7ml/kg and 15ml/kg of anemic plasma filtrate was injected to 2 groups of rats respectively for 7 and 8 days. Hemoglobin concentrations, red blood cell counts and reticulocyte counts were observed before and after injection of anemic plasma and no change was induced by the injection. Subsequently, it was concluded that there was no erythropoietin of high titer in the plasma of chronic post-hemorrhagic anemic men.
카드륨 독성에 대한 부추 (Allium Odorum L.) 의 방어효과
안령미(Ryoung Me Ahn),김완태(Wan Tai Kim),이희성(Hi Sung Lee) 한국환경보건학회 1991 한국환경보건학회지 Vol.17 No.2
This study aimed to find out the effect of freeze -drying leek against cadmiurn poisoning on the cholesterol and enzyme activities in serum and superoxide radical, SOD and catalase in liver and kidney of the rnale rats during the administrered period. ln this experiment, male rats of SPragμe-Dawley strain were used. The rats were divided into 3 groups which were fed different1y either for 5 weeks or for 10 weeks : basal diet, basal diet and cadmium in water and 3 % leek added diet and cadmium in water. Cadmium was administered ad libltum 100 ppm CdCh in water. The followings are the results of this experiment. l. Leek reduced the cholesterol and the activities of GPT increase resulted from cadmium treatment. 2. Leek reduced the rate of cadmium in liver and kidney. 3. Leek reduced the activities of SOR and catalase in liver and kidney, while it enhanced the activities of SOD. 4. Leek reduced the necrosis and swelling in liver and kidney casused by cadmium treatment. This experiment showed that leek -addition group had protective effect agair:st cadmium pois oning and increased ALPase activities in serum. Leek alleviated GPT activities m serum and cad•rnium concentration, necrosis, and swelling in liver and kidney, Therefore, this experiment con c1uded that leek has defenslve power against cadmium poisoning.