유방의 당원성 투명세포암종의 세침흡인 세포학적 소견 - 2예 보고 -

김완섭,이원미,홍은경,박문향,이중달,Kim, Wan-Seop,Lee, Won-Mi,Hong, Eun-Kyung,Park, Moon-Hyang,Lee, Jung-Dal 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.2

Glycogen-rich clear ceil carcinoma of the breast is an unusual variant of carcinoma with a recorded incidence of $1.4{\sim}3%$ of breast carcinomas. The cytologic characteristics have not been well described. We report two cases of glycogen-rich clear cell carcinoma with corresponding fine needle aspiration(FNA) cytologic findings and compare them to infiltrating ductal carcinoma and other clear ceil malignancies with a review of literature. One was a 62-year-old woman exhibiting a palpable mass of the right breast. The smears showed atypical tight cell clusters and individually scattered single cells containing leanly or clear abundant cytoplasm with well defined cytoplasmic margins. Mild to moderate nuclear pleomorphism and a prominent nucleolus were present. The other was a 42-year-old woman who was admitted with a right breast mass. The smears showed moderately cellular, tightly cohesive tumor cells. The cytoplasmic outline was generally well demarcated. The tumor cells Contained foamy to clear abundant cytoplasm with large and small vacuoles. The nuclear pleomorphism was marked. Both tumors resected by modified radical mastectomy, were diagnosed as glycogen-rich clear cell carcinoma. Histologically, the clear cell nature of tumor cells were not characteristic enough to predict this type of the tumor. Some cytologic features can be distinguished other clear cell breast cancer from glycogen-rich carcinoma. Recognition of these unusual patterns in a breast FNAC should raise the suspicion of a clear cell carcinoma including glycogen-rich subtype. Cytological localization of glycogen using PAS and D-PAS staining may permit the correct Identification and differential diagnosis of this tumor.

폐에 발생한 염증성 가성종양의 세침흡인 세포학적 소견 - 선암종으로 오진한 1예 보고 -

김완섭,홍은경,박문향,Kim, Wan-Seop,Hong, Eun-Kyung,Park, Moon-Hyang 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.2

Cytologic features of inflammatory pseudotumor of the lung have not been described frequently. We report fine needle aspiration cytologic(FNAC) finding of a case of inflammatory pseudotumor misdiagnosed as adenocarcinoma in a 63-year-old man. The FNAC displayed a mixture of histiocytes, myofibroblasts, pneumocytes, and plasma cells. Some histiocytes and myofibroblasts had large nuclei with irregular nuclear membrane and prominent nucleoli, which mislead the diagnosis on adenocarcinoma on FNAC. The heterogeneous cell population is the unique cytologic features of inflammatory pseudotumor, which are helpful to distinguish it from other circumscribed benign and malignant lesions. Familiarity with these features is essential to avoid misdiagnosis and possible overtreatment.

폐암의 세포진단: 진단의 정확도와 함정

김완섭,Kim, Wan-Seop 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.1

The role of respiratory cytology is to detect and classify pulmonary disease, with an emphasis of neoplastic disease, so that proper therapy can be instituted. As in many branches of cytology, the recognition of malignancy in the cells obtained from the respiratory tract is more straightforward than identifying the type of tumor cell. It is important to accurately determine the true cytopathological cell type in cases of primary lung cancer and to know the accuracy of the diagnosis achieved by the cytological procedures. The well differentiated tumors have characteristic cytoplasmic and nuclear abnormalities that enable physicians to firmly categorize these lesions, as in squamous cell or adenocarcinoma, but some moderately and most poorly differentiated tumors show few distinctive features. This article reviews the malignant and reactive pulmonary cytologic findings and we also report on some of their pitfalls and the cytologic criteria.

폐로 전이한 Wilms 종양의 세침흡인 세포학적 소견 - 2예 보고 -

김완섭,김남훈,고영혜,박문향,이중달,Kim, Wan-Seop,Kim, Nam-Hoon,Koh, Young-Hyeh,Park, Moon-Hyang,Lee, Jung-Dal 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2

We describe two cases of metastatic Wilms' tumor in the lung with emphasis on the cytologic features of specimens obtained by needle aspiration. One of them was extrarenal Wilms' tumor. The findings were correlated with the histopathologic features of the primary lesion. Cellular components in the fine needle aspiration cytology (FNAC) slides included blastemal, epithelial, stromal and inflammatory cells with immature tubular differentiation and rosette formation. Recognition of these cellular components in FNAC smears help in establishing FNAC diagnosis of Wilms' tumor. The blastemal cells were represented by small to medium sized cells with scanty cytoplasm having ill-defined borders and round to slightly oval nuclei with evenly dispersed chromatin and small marginated nucleoli. They were seen in our two cases. The differential diagnosis includes neuroblastoma, malignant lymphoma, malignant rhabdoid tumor, clear cell sarcoma, Ewing's sarcoma and embryonal rhabdomyosarcoma. In conclusion, making a definite cytologic diagnosis of metastatic Wilms' tumor may be possible by light and electron microscopy and immunohistochemical staining. The above findings may contribute to the diagnosis of FNAC of metastatic Wilms' tumor.

경구개에 발생한 다형성 저등급 선암종의 세침흡인 세포학적 소견 - 1예 보고 -

김완섭,전석훈,홍은경,박문향,이중달,Kim, Wan-Seop,Jeon, Seok-Hoon,Hong, Eun-Kyung,Park, Moon-Hyang,Lee, Jung-Dal 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.2

Polymorphous low grade adenocarcinoma(PLGA) is a rare malignant tumor of the salivary gland. It is characterized by diverse histology, bland-locking cytology indolent behavior and favorable prognosis. The fine needle aspiration cytologic features of PLGA are described. The aspirates from the hard palate in a 33-year-old woman showed cellular smear composed of monotonous small round to oval cells with scanty cytoplasm. Papillary, tubular and cell ball arrangements with characteristic dense stromal spheres were recognized. PLGA could be suggested by fine needle aspiration cytology, if one encountered cellular smear with various architectures and uniform bland-locking cytologic feature.

데이터마이닝을 이용한 신혼여행상품의 시장세분화

김완섭(Wan Seop Kim),강미라(Mi Ra Kang),류시영(Si Young Ryu) 한국관광연구학회 2010 관광연구저널 Vol.24 No.3

In tourism marketing promotion, it is important to know the tourists purchase pattern and target market. The purpose of this study is to investigate the tourism market segmentation of honeymoon tourists and the factors influencing the decision making patterns. 5,482 samples of honeymoon packages transaction data were obtained from the travel agency. In this paper, empirical analysis of secondary data applying data mining techniques is presented. Data mining is a technique for extracting interesting knowledges from a large set of data. The model employs the decision tree algorithm. The CHAID analysis shows that the most important factors for decision making patterns are `travel agency location` and `price of honeymoon packages`. And the CART analysis shows that the most important factors is `price of honeymoon packages`. In addition to providing useful implication for tour planners and marketers of travel agencies, this study also give a theoretical contribution to tourism marketing research. And this paper represents the effective database marketing strategy by applying the data mining technique to the travel agencies` marketing system. Based on these significant findings, theoretical implications and limitations of the study are discussed.

의사결정트리를 이용한 교육성과 요인에 관한 연구

김완섭(Wan Seop Kim) 한국공학교육학회 2010 공학교육연구 Vol.13 No.4

대학에서 운영되는 강좌를 효과적으로 관리하고 교육성과를 향상시키기 위해서는 각 클래스의 현재의 교육성과를 진단하고 교육성과에 영향을 미치는 요인들을 파악하는 과정이 요구된다. 요인을 발견하는 연구에는 연관성 분석, 회귀분석 등의 통계기 법들이 많이 사용되고 있으며 최근에는 데이터마이닝의 결정트리 분석도 사용되고 있다. 결정트리 분석은 결과 모델을 이해하기 쉽고 의사결정에 적용하기 쉽다는 장점이 있지만, 다중공선성 등의 입력 데이터의 특성에 견고하지 못한 문제점이 있다. 본연구에서는 기존의 결정트리 분석의 문제점들을 정리하고, 이 문제점들을 보완하기 위한 하나의 실험적 해결책으로 다중 결정 트리를 이용한 요인의 발견 방법을 제안한다. 실험을 통해 다중 결정트리를 수행이 다중 결정트리를 적용할 때보다 신뢰할 수있는 요인을 발견하고 각 변수의 중요성을 발견할 수 있음을 보였다. In order to manage the lectures efficiently in the university and improve the educational outcome, the process is needed that make diagnosis of the present educational outcome of each classes on a lecture and find factors of educational outcome. In most studies for finding the factors of the efficient lecture, statistical methods such as association analysis, regression analysis are used usually, and recently decision tree analysis is employed, too. The decision tree analysis have the merits that is easy to understand a result model, and to be easy to apply for the decision making, but have the weaknesses that is not strong for characteristic of input data such as multicollinearity. This paper indicates the weaknesses of decision tree analysis, and suggests the experimental solution using multiple decision tree algorithm to supplement these problems. The experimental result shows that the suggested method is more effective in finding the reliable factors of the educational outcome.

구매 데이터에 적합한 아이템 기반의 협력적 추천 기법

김완섭(Wan-Seop Kim),윤찬식(Chan-Sik Yune),이수원(Soowan Lee) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1B

협력적 추천 알고리즘의 성능향상을 위한 많은 연구들이 진행되고 연구 결과로 다양한 협력적 추천 기법들이 제안되고 있다. 이러한 연구에서는 EachMovie, MovieLens등의 선호도(Rating) 값을 기반으로 하는 데이터를 대상으로 추천의 효율을 높이고자 하고 있다. 그러나 실세계에서 우리가 얻을 수 있는 원 거래 데이터(Raw Transaction Data)는 선호도 값을 갖고 있지 않다. 따라서 실세계의 구매 데이터에 효과적인 추천을 하기 위해서는 기존의 선호도 기반 알고리즘이 아닌 구매 정보만을 기반으로 하는 변경된 협력적 추천 알고리즘이 필요하다. 본 논문에서는 연관규칙 탐사 기법에서 사용하는 확신도(confidence)를 유사도식에 사용하고 이를 기반으로 선호도를 예측하는 구매 기반의 협력적 추천 알고리즘을 제안한다.

주거침입죄에 관한 고찰

김완섭 ( Wan Seop Kim ) 순천향대학교 사회과학연구소 2004 사회과학연구 Vol.10 No.3

개괄적 고의에 관한 고찰

김완섭 ( Wan Seop Kim ) 순천향대학교 사회과학연구소 2003 사회과학연구 Vol.9 No.1