제2수지-제4수지 길이 비율과 대뇌 편측화 관계 연구

김아영,김성균,윤진영,정재승,이주호,채정호,이유상,Kim, Ah-Young,Kim, Seong-Kyun,Youn, Jin-Young,Jeong, Jae-Seung,Lee, Joo-Ho,Chae, Jeong-Ho,Lee, Yu-Sang 대한생물정신의학회 2011 생물정신의학 Vol.18 No.1

Objectives : Cerebral laterality is thought to be an important marker for neurodevelopment. Prenatal testosterone could influence both cerebral laterality and 2nd to 4th finger length ratio(2D : 4D). EEG coherence and 2D : 4D were examined to investigate the relationship between prenatal testosterone level and cerebral laterality. Methods : EEG was recorded in 24 healthy subjects in the eyes closed resting state. Differences in 2D : 4D finger ratio were used to discriminate "masculine finger type" and "feminine finger type" groups. The 2D : 4D ratio was lower and greater than one for the "masculine finger type" group and "feminine finger type" group, respectively. We used coherence analysis to estimate the cortical functional connectivity. Results : There were statistically meaningful relationships among cerebral functional connectivity, sex and finger ratio. Man and masculine finger type group showed higher intra-hemispheric coherence than those of woman and feminine finger type group. Woman and feminine finger type group showed higher inter-hemispheric coherence than those of man and masculine finger type group. Conclusions : These results imply that prenatal testosterone might act as important determinants of cerebral laterality. Further examination of the relationship between 2D : 4D and EEG coherence in schizophrenia could give some clues for the neurodevelopmental hypothesis of schizophrenia genesis.

A new record of the Genus Pachyserica Brenske, 1897 (Coleoptera, Melolonthidae) in Korea

김아영,박상욱,Kim, A Young,Park, Sang Wook Korean Society of Applied Entomology 2020 한국응용곤충학회지 Vol.59 No.1

한국산 미기록속 비늘우단풍뎅이속(신칭)의 미기록종인 제주비늘우단풍뎅이(Pachyserica yanoi)를 보고한다. We recognized Pachyserica yanoi Nomura which belongs to the genus Pachyserica Brenske, 1897 (Coleoptera, Melolonthidae) in Korea for the first time. A key to the genera of Korean Sericini, diagnosis and photographs of this species are provided.

A New Species of the Genus Euseius (Acari: Phytoseiidae) from Ulleungdo Island in Korea

김아영,서홍렬,류면옥,Kim, A Young,Seo, Hong Yul,Ryu, Myon Ok Korean Society of Applied Entomology 2019 한국응용곤충학회지 Vol.58 No.1

신종인 울릉이리응애(Euseius ulleungensis) (신칭)를 기재한다. 이 신종은 울릉도 섬쑥부쟁이에서 채집되었다. A new species, Euseius ulleungensis sp. nov. is described from Korea. The new species was collected on Aster glehni Fr. Schm. at Jeodong, Ulleung-up, Ulleung-gun, Gyeongsangbuk-do.

Chlorantraniliprole 저항성 초파리 계통 확립과 저항성 특성 구명

김아영,권덕호,정인홍,특안판,트란비느안,이시혁,고영호,Kim, A-Young,Kwon, Deok Ho,Jeong, In Hong,Thuc, Ahn Phan,Tran, Vi Ngan,Lee, Si Hyeock,Koh, Young Ho 한국응용곤충학회 2016 한국응용곤충학회지 Vol.55 No.4

Chlorantraniliprole은 곤충 근육의 $Ca^{2+}$ 농도를 조절하는 Ryanodine 수용기(RyR)에 작용 하는 diamide계통의 작물보호제이다. 최근에 보고된 chlorantraniliprole 저항성 배추좀나방 계통은 RyR에 돌연변이를 가지고 있다. 본 연구에서는 초파리를 모델 곤충으로 저농도와 고농도의 chlorantraniliprole로 도태된 두 종류의 저항성 계통을 확보하였다. 두 종류의 저항성 계통은 접촉독성과 섭식독성 평가법을 활용하여 저항성 지수를 산출하였다. 접촉 독성 평가에서 두 종류의 저항성 계통은 대조군과 비교하여 95% 신뢰구간에서 저항성 발달에 차이가 없었지만, 섭식 독성 평가의 경우에서는 고농도 저항성 계통과 저농도 저항성 계통에서 대조군 대비 각각 2.1배와 8.1배의 통계적으로 유의한 저항성 증가가 나타났다. 작용점 유전자인 RyR 발현량 비교 결과, 두 종류의 저항성 계통에서 RyR의 발현량이 유의하게 감소하였고, 주요 약제 관련 효소인 Acetylcholinesterase와 Glutathione-S-transferase 활성은 조직 특이적으로 증가하는 것을 확인하였다. 이러한 결과들은 초파리에서 chlorantraniliprole에 대한 섭식독성 저항성의 발달에는 주요 해독 관련 효소의 과활성도 관여할 것 임을 보여주고 있다. Ryanodine receptors (RyRs) regulate the contractions of insect muscles by altering intracellular $Ca^{2+}$ concentration and are the targets of chlorantraniliprole. Recently, a chlorantraniliprole-resistant strain was reported in the diamondback moth Plutella xylostella by obtaining point mutations on the RyRs. In the present study, we established two resistant strains from Drosophila melanogaster, which were treated with low or high concentrations of chlorantraniliprole, and their resistance levels were determined on the basis of contact and ingestion toxicities. Compared with the control strain, the two resistant strains did not show any significant differences in contact toxicity. However, they showed significantly increased resistance ratios in ingestion toxicity than that by the control strain. The low and high concentration resistant strains exhibited 2.1- and 8.1-fold increased resistance ratios, respectively, compared with that by the control strain. Moreover, we found that the resistant strains had altered expression levels of RyRs and more enhanced Acetylcholinesterase and Glutathione-S-transferase activities than that by the non-selected strain. These results suggested that the resistance development of chlorantraniliprole in the two strains might be mediated by the activation of detoxification pathways in D. melanogaster.

자동차 엔진룸용 전장품 유무연 솔더 접합부의 열화특성

김아영,홍원식,Kim, A Young,Hong, Won Sik 대한용접접합학회 2014 대한용접·접합학회지 Vol.32 No.3

Due to environmental regulations (RoHS, WEEE and ELV) of the European Union, electronics and automotive electronics have to eliminate toxic substance from their devices and system. Especially, reliability issue of lead-free solder joint is increasing in car electronics due to ELV (End-of-Life Vehicle) banning from 2016. We have prepared engine control unit (ECU) modules soldered with Sn-40Pb and Sn-3.0Ag-0.5Cu (SAC305) solders, respectively. Degradation characteristics of solder joint strength were compared with various conditions of automobile environment such as cabin and engine room. Thermal cycle test (TC, $-40^{\circ}C$ ~ ($85^{\circ}C$ and $125^{\circ}C$), 1500 cycles) were conducted with automotive company standard. To compare shear strength degradation rate with eutectic and Pb-free solder alloy, we measured shear strength of chip components and its size from cabin and engine ECU modules. Based on the TC test results, finally, we have known the difference of degradation level with solder alloys and use environmental conditions. Solder joints degradation rate of engine room ECU is superior to cabin ECU due to large CTE (coefficient of thermal expansion) mismatch in field condition. Degradation rate of engine room ECU is 50~60% larger than cabin room electronics.

Food Choice Questionnaire 방법을 적용한 식품선택 동기요인 분석

김아영,이슬기,이민아,Kim, A Young,Lee, Seul Ki,Lee, Min A 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.3

The purpose of this study was to analyze the motives for food choice using a Food Choice Questionnaire (FCQ). A FCQ, an instrument that measures the reported importance of nine factors underlying food choice, was administered to a representative sample of 157 adult respondents from 21 to 27 October 2013. Statistical analyses such as Descriptive statistics, Factor analysis, Reliability analysis, Pearson correlation, independent samples t-test, and analysis of variance (ANOVA) were performed on the data using the SPSS PASW Statistics 18.0 for Windows. According to the results, five food choice motivation factors were discerned: health, sensory and mood, convenience, price, and familiarity. The most important factors reported were price, sensory and mood, convenience, health and familiarity. We found that food choice motivation is distinguished by age, frequency of eating out, and consumption of HMR. Females in this study gave higher importance scores to health, sensory and mood, and familiarity. There were higher correlations between 'health' and 'sensory appeal and mood'.

자동차 전장품용 무연솔더 접합부의 시리즈 시험 유효성

김아영,오철민,홍원식,Kim, A Young,Oh, Chul Min,Hong, Won Sik 대한용접접합학회 2015 대한용접·접합학회지 Vol.33 No.3

Due to environmental regulations (RoHS, WEEE and ELV) of the European Union, electronics and automotive electronics have to eliminate toxic substance from electronic devices and system. Specifically, reliability issue of lead-free solder joint have an increasing demand for the car electronics caused by ELV banning. The authors prepared engine control unit and cabin electronics soldered with Sn-3.0Ag-0.5Cu (SAC305). To compare with the degradation characteristics of solder joint strength, thermal cycling test (TC), power-thermal cycling test (PTC) and series tests were conducted. Series tests were conducted for TC and PTC combined stress test using the same sample in sequence and continuously. TC test was performed at $-40{\sim}125^{\circ}C$ and soak time 10 min for 1000 cycles. PTC test was applied by pulse power and full function conditions during 100 cycles. Combined stress test was tested in accordance with automotive company standard. Solder joint degradation was observed by optical microscopy and environment scanning electron microscopy (ESEM). In addition, to compare with deterioration of bond strength of quad flat package (QFP) and chip components, we have measured lead pull and shear strength. Based on the series test results, consequently, we have validated of series test method for lifetime and reliability of Pb-free solder joint in automotive electronics.

온라인 음원유통 동향

김아영,박찬우,채원석,서정혜,이준우,양웅연,Kim, A.Y.,Park, C.W.,Chae, W.S.,Suh, J.H.,Lee, J.W.,Yang, U.Y. 한국전자통신연구원 2015 전자통신동향분석 Vol.30 No.4

스마트 기기와 네트워크 인프라의 발전을 바탕으로 음원시장의 디지털화가 빠르게 진행되고 있으며, 온라인 음원유통 방식이 다양화됨에 따라 온라인 음원에 대한 체계적인 관리와 효율적인 유통체계 구축의 필요성이 증대되고 있다. 본고에서는 온라인 음원유통에 사용되는 국내외 식별체계에 대해 설명하고, 온라인 음원유통을 위한 플랫폼과 표준화 동향에 대해 설명하고, 향후 온라인 음원유통의 발전방향에 대해 기술하고자 한다.

항로표지 관리 및 배치 의사결정 지원을 위한 항로표지 운용 소프트웨어 개발에 관한 연구

김아영,이영주,박세길,오재용,김연규,Kim, Ah-Young,Lee, Yeong-Ju,Park, Se-Kil,Oh, Jae-Yong,Kim, Yeon-Gyu 해양환경안전학회 2014 海洋環境安全學會誌 Vol.20 No.5

본 연구에서는 항로표지 시뮬레이터에서 구축된 항로표지 데이터베이스를 쉽게 관리하고 활용할 수 있는 방안과 항로표지 배치에 대한 의사결정을 지원하기 위한 방안을 모색하고자 하였다. 시나리오와 같은 계층 구조와 이력카드, 상태 부여 등을 통해 항로표지 데이터베이스를 관리하는 방안을 검토하고 항로표지 배치안에 대하여 시각적, 청각적, 정량적인 검증을 할 수 있도록 돕는 항로표지 운용 소프트웨어를 구현함으로써 본 연구의 목적을 달성한다. 항로표지 운용 소프트웨어는 항로표지 신설, 이설 등과 같이 자유로운 제어뿐만 아니라 조건 검색, 가상운항 및 정량 평가 결과 전시 등의 다양한 기능을 통해 항로표지 배치계획에 대한 의사결정을 돕는다. 이를 활용하여 여러 설계안에 대해 선박이나 선원에게 미칠 수 있는 영향을 예측하거나 설계안의 효율성 및 적절성 여부를 판단하는데 도움을 주고, 수월해진 검증 방법을 통해 더 다양한 설계안을 비교할 수 있기 때문에 항로표지 설계 및 배치 계획 시에 발생 할 수 있는 실패비용과 항로표지 관리비용을 감소시킬 것으로 기대된다. This study has searched to find a program in order to manage simply and practically use the expelled AtoN database from the AtoN Simulator and to support the idea decision for the AtoN placement. It examines a program that manages AtoN database through the hierarchy structure, history card and endowment with condition same as a scenario. And accomplishes this study's goal owing to realizing AtoN operational software that helps for visual, hearing sense, fixed amount verification upon AtoN placement project. The AtoN operational software contributes not only flexible control like a newly establishment, relocation etc, but also supports idea decision for AtoN placement plan through many functions such as condition search, virtual sailing and fixed amount appraisal result exhibition, etc. Through utilization of this, it is to help upon the presupposition of the impact to ship or sailor about many designs and in addition, upon the judgment of whether or not for the efficiency and appropriation of the design. It is expected to reduce possible failure costs and management costs due to AtoN design and placement plans, because to compare more various designs thru the easier verification method.

소나무재선충[Bursaphelenchus xylophilus (Steiner and Buhrer) Nickle]의 GaLectin에 대한 특이적인 단클론 항체 제작과 진단에의 활용

김아영,김영하,최보혜,트랑뉴겐,윤경재,이시혁,한혜림,고영호,Kim, A-Young,Kim, Young Ha,Choi, Bo-Hye,Nguyen, Trang,Yoon, Kyungjae Andrew,Lee, Si Hyeock,Han, Hye-Rim,Koh, Young Ho 한국응용곤충학회 2018 한국응용곤충학회지 Vol.57 No.1

소나무재선충(pine wood nematode, PWN) 감염 소나무를 현장에서 신속하게 진단을 할 수 있는 방법은 현재 없다. 본 연구에서는 PWN특이적인 항원으로 알려진 PWN-GaLectin을 baculovirus발현체계로 발현시켜서 총 1,464개의 fusion hybridoma 세포 주 라이브러리를 제작 하는 항원으로 이용하였다. 총 1,464개의 fusion hybridoma 세포 주 중, PWN-GaLectin에 대한 높은 반응을 보이는 62개의 fusion hybridoma 세포 주를 선별했다. 이들 중, 표준 PWN 감염소나무 PBS추출물과 PWN 단백질 추출물에 강한 반응을 보이는 세포 주 12개를 선별하여 단클론 항체(monoclonal antibody, Mab) 분비세포 주 확립을 위한 limited dilution을 실시하였다. Mab분비세포 주 확립을 위해서 표준 PWN 감염소나무 추출물에 대한 반응이 표준 정상 소나무 추출물 보다 높은 세포 주들을 선별했다. 그리고 추가로 PWN 단백질 추출물에 대해서 3종의 비 병원성 선충 단백질 추출물 보다 높은 반응을 보이는 세포 주들도 선별, 확립했다. 본 연구에서 확립된 Mab들을 우리는 현장과 실험실에서 사용할 수 있는 신속진단키트의 개발에 이용할 수 있을 것이다. Currently, there is no available tool that rapidly diagnoses pine wood nematode (PWN)-infected pine trees in the field. In this study, we synthesized and purified PWN Galectin, which might be an antigen specific to PWN, using the Baculovirus expression system. We used PWN Galectin as an antigen for generating 1,464 fusion hybridoma cell lines secreting monoclonal antibodies (Mabs). Among them, we selected 62 fusion hybridoma cell lines showing high reactivity to PWN Galectin. We further selected 12 fusion hybridoma cell lines showing high reactivity to the standard PWN-infected pine tree phosphate buffered saline (PBS) extract. Additionally, two fusion hybridoma cell lines showing no or extremely low reactivity were used as controls. The selected fusion hybridoma cell lines were subjected to limiting dilutions for selecting and establishing Mab-secreting cell lines showing higher reactivity to the standard PWN-infected pine tree extract than to the standard normal pine tree PBS extract. Moreover, the selected fusion hybridoma cell lines were further selected based on their higher reactivity to PWN protein extracts than to three non-pathogenic nematode protein extracts. The Mab-secreting cell lines established in this study could be used to develop rapid diagnostic tools that can be used in the field or in laboratories for detecting PWN-infected pine trees or PWN.